Cohen, M.S., Bookheimer, S.Y. (1994). TINS 17(7), 268-77.

Cohen, M.S., Bookheimer, S.Y. (1994). TINS 17(7), 268-77.

500 m

A B C

IVc-

IVc-

III

III

IVa

IVb

VVI

wm

length density

V1 IVc-IVc-

IIIIIIIVaIVb

VVIwm

0 500 1000

[mm/mm³]

III

III

IV

VI

V

A6 A5 A4A3 A2A1 V5 V4V3 V2 V1

500 m

500 m

Macaque superior temporal gyrus

50 m

50 m

20 m

100 m

internal pia and glia limitans

arachnoid space

pial spaceexternal pia

internal arachnoid

upper molecular layer

100 m

50

0

m

glial cell layer

Neuronen

Astrozyten

Dilatation

Konstriktion

BlutgefässGlattmuskelzellen

Arachidonsäure

NONOS

NeuronenGlu

Glu NMDA

mGluR

NeuronenNA

NA

[Ca2+i]

1

(Inter-)Neuronen

GABA

NeuronenHirnstamm

ACh5HT

Neuropeptide(VIP, NZ, SOM)

P450/COX

Prostaglandine

HETE

Cortex

Optik

CCDKamera

Computer

Lichtquelle

AbsorptionStreuung

-5 0 5 10 15 20 25-5

0

5

10

time [sec]

s

ign

al [

%]

HbR

HbO

HbT

BOLD