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Clinical Use of Blood The AIM II Trial Challenges of Near-Live Organisational Blood Use Monitoring
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Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Mar 22, 2020

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Page 1: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Clinical Use of Blood The AIM II Trial

Challenges of Near-Live Organisational Blood Use Monitoring

Page 2: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Goals for AIM

Assist hospitals in complying with timely metric driven standardsCreate an inclusive approach to blood managementTo reduce costs of blood by tracking Key Performance Indicators (KPIs)Providing reports with national (and international) benchmarking to reveal evidence based best practice

Page 3: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

How can we find out how blood is being used at the moment?

Only by time consuming retrospective studies or prospective audit

Or by asking transfusion teams for information

Page 4: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Blood Stocks Management Scheme

Intelligence on blood inventory management gathered from across the blood supply chainStock and wastage levelso Red cells o Platelets

BenchmarkingTransparency of data Significant improvements in inventory management

Better information on stock management and wastage.....

Page 5: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

O Neg

Page 6: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase
Page 7: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Red Cell Demand in England & N Wales

Page 8: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Platelet Demand in England & N Wales

Page 9: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

‘Appropriate Inventory Management’(AIM) OverviewPhase I (Module1)

BSMS source code provided by NHSBTCollaboration between NHSBT/America s Blood Centres (ABC)American name: AIM I (Appropriate Inventory Management Module I)

Phase II (Module 2)

Goal: for vein to vein monitoring of blood components (AIM II)Blood utilisation management requires patient level transfusion data in order to determine meaningful and appropriate use

Page 10: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Trial of AIM II in England: Trial in collaboration with 4 hospitals

Present overview of system to hospital teams to enable evaluation of the resources requiredEvaluate the AIM II system functionality, assessing the fit for collection of blood use dataWork with hospitals to establish data extraction & submission procedures Goal: a monthly data submission and reportingBenchmarking reports provided to hospitals

Page 11: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase
Page 12: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Data Elements for Blood Utilisation Analysis

Transfusion yes or no?Patient ID (encrypted)Date of admission and dischargeYear of birthGenderHealthcare Resource Group (HRG)Date and time of transfusionTransfused componentPre transfusion lab test resultDonation number and product codeExpiry date

Page 13: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Data elements for transfusion outcome evaluation

Mortality FlagOrdering physicianDirectorate

Page 14: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Patient level transfusion data is needed to determine appropriate use:

where are these data?

Page 15: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Data warehouse hosted by ABC (in trial)

Analysis and reports

PAS coded data related to transfusion episode (ICD 10

diagnosis code, OPCS4 procedure code)

Data mining software extracts relevant data (no patient identifiable features)

PAS data related to length of stay,

consultant, specialty

LIMS data related to transfusion episode

Data related to blood use

Data related to blood results

Page 16: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

So, where do you start??

Page 17: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Challenges

Page 18: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase
Page 19: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase
Page 20: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase
Page 21: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Potential future integration:Recording the clinical reason for blood use

The use of HRG is the reason for transfusion o This is less accurate for medical reasons for transfusion

AIM II would be more easily targeted if there were a field in LIMS with a coded reason for clinical useThe code should be from a standardised menu and would be selected by the person requesting the transfusion (ideally by electronic order comms)

Page 22: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Potential benefits of AIM II

Better understanding of where and why blood is being used.Provide hospitals and physicians with benchmarking data.At individual hospital level, will be able to establish baseline performance and how it compares to regional, national or international peersSpringboard for inter-hospital collaborations to identify best practice.

Page 23: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

NHSBT will benefit as knowledge of clinical use will inform strategic planningo Ensure sufficiency of supplyo Maintain appropriate inventory levels

to ensure supply meets demando Information to evaluate safety

decisionso Support emergency planning

Potential benefits of AIM II

Page 24: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Summary

The goal of AIM II is to assist hospitals and physicians together with NHSBT to better manage and use the available blood supply

Wide implementation would potentially offer local, regional, national and international benchmarking

Challenges of data collection and clinical buy-in

Further development will depend on the outcome of the current trial

Page 25: Clinical Use of Blood The AIM II Trial · Clinical Use of Blood The AIM II Trial Challenges of Near-LiveOrganisational ... ‘Appropriate Inventory Management’ (AIM) Overview Phase

Thank you

Thanks to NHSBT