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CIPLUKAN FLOWER By : T.Chrestella Meryl 11.70.0020 Yuni Rusiana 11.70.0055 Yoceline Natania 11.70.0036 Jonathan Ali 11.70.0107 Febby Ernita S 11.70.0054 Tjan, Ivana 12.70.0057 Nora Csillag
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Page 1: Ciplukan flower

CIPLUKAN FLOWER

By :T.Chrestella Meryl11.70.0020Yuni Rusiana 11.70.0055Yoceline Natania 11.70.0036Jonathan Ali 11.70.0107Febby Ernita S 11.70.0054Tjan, Ivana 12.70.0057Nora Csillag

Page 2: Ciplukan flower

Outline

Introduction

Bioactive Compounds & Functions

Application

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INTRODUCTION (2)

The classification of Ciplukan flower Kingdom : Plantae Division : Spermatophyta Class : Dicotyledonnae Ordo : Solanales Family : Solanaceae Genus : Physalis Species : P. angulata L

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BIOACTIVE COMPOUNDS (1) Leaves : physalin B, D, E, F, G, H, I, and K. Root, leaves, flower : saponin, with

angulatin A and flavonol glycoside (example : myrcetin neohesperidoside, pigrin as alcaloid compound)

Fatty acid : palmitic and stearate acid Fruits : 24,5 mg of vitamin C, 6% of

sugar, and 7% of protein in 100 ml of juice and rich in cryophytoxanthin

Terpenes, flavonoid and citric acid.

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BIOACTIVE COMPOUNDS (2)

1. Saponins and alkaloid : bitter taste, efficacious as anti tumor and prevented cancer growth, especially colon cancer whereas flavonoids acted as antioxidant

2. Physalin : prevent the growth of some cancer cells, whereas B physalin was cytotoxic to some of cancer cell and leukemia cancer cells.

3. Etanolic : cytotoxic effect and trigger the apoptosis in breast cancer.

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BIOACTIVE COMPOUNDS (3)4.Antidiabetic : leaf extract with 20% and 40% had the

effect of decreasing glucose concentration on mencit.

5. Myrcetin neohesperidoside : strong cytotoxicity against the three tested cell lines. The strongest action being observed with lymphocytic leukemia P-388 cells

6. Antimicrobial : physalin-containing fractions were effective in against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium kansasii, Mycobacterium malmoense and Mycobacyterium intracellulare

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BIOACTIVE COMPOUNDS (4)

7. Antiinflammatory : 5 mg/kg extract of Physalis angulata L. effective effects to treat the acute and chronic skin inflammatory conditions

not recommended to eat immature ciplukan flower because it had a toxic effect like the other family of solanacea.

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APPLICATION (1)

1. Traditional medicine Laxative Drugulcers bleeding gums Sprains Stomachache Gonorrhea Diabetes Epilepsy Inflammation throat infections Diuretic analgesic (pain relieving) neutralizing toxins activating the body's glandular functions.

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APPLICATION (2)

2. Food ApplicationA. TEAmade from leaves and stem of ciplukan which if consumed three times a day can help to cure influenza,whooping cough, bronchitis, and paroritis

B. TRADITIONAL BEVERAGE boil the ciplukan plant such as leaves, root, flower orstem with water for some minutes.

C. SALAD eaten rawD. DESSERT E. FLAVORING F. FRUIT PRESERVES/ DRIED G. PIE FILLING contain pectin 

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REFERENCES http://kaskushootthreads.blogspot.com/2014/07/ciplukan-tanaman-beribu-manfaat yang.html. Accesed on October

1st, 2014.

BPOM RI. (2007). Acuan Sediaan Herbal, Ed. I. Vol. 3. BPOM RI. Jakarta.

Fitria M., Armandari I., Septhea D.B., Hermawan A., Ikawati M., Meiyanto E. (2009). Ekstrak Etanolik Herba Ciplukan (Physalis Angulata L) Berefek Sitotoksik dan Menginduksi Apoptosis Pada Sel Kanker Payudara MCF-7. Cancer Chemoprevention Research 1-10.

Hall D.W., Vandiver V.V., Sellers B.A. (1991). Cutleaf Ground-cherry, Physalis angulata L. Florida, USA: University of Florida.

Ismail N., Alam M. (2001). A Novel Cytotoxic Flavonoid Glycoside From Physalis angulata. J. Fitoterapia 72 : 676-679.

Kemenkes RI. (2011). Formularium Obat Herbal Asli Indonesia Vol 1. DIPA Satuan Kerja Direktora Bina Pelayanan Kesehatan Tradisional, Alternatif dan Komplementer. Jakarta.

Pietro R.C.L.R., Kashima S., Sato D.N., Januario A.H., Franca C. (2000). In Vitro Antimycobacterial Activites of Physalis angulata L. Phytomedicine Vol 7(4) : 335-338.

Pinto N.B., Morais T.C., Carvalho K.M.B., Silva C.R., Andrade G.M., Brito G.A.C., Veras M.L., Pessoa O.D.L., Rao V.S., Santos F.A. (2010). Topical Anti-Inflammatory Potential Of Physalin E From Physalis Angulata On Experimental Dermatitis in Mice. J. Phytomedicine 17 : 740-743.

Purnamasari, A. (2012). Ceplukan (Physalis minima L.). Universitas Indonesia.

Sediarso, Sunaryo H., Amalia N. (2008). Efek Antidiabetes Dan Identifikasi Senyawa Dominan Dalam Fraksi Kloroform Herba Ciplukan (Physalis angulata L.). J. Farmasi Indonesia 4(2) :63-69.

Suijatmo A.B., Sukandar E.Y., Ratnawati Y., Kusmaningati S., Wulandari A., Narvikasari S. (2011). Efek Antidiabetes Herba Ciplukan (Physalis Angulata LINN) Pada Mencit Diabetes Dengan Induksi Aloksan. J. Farmasi Indonesia 5(4) : 166-171.

Yulianto, D. (2009). Inhibisi Xantin Oksidase Secara In Vitro oleh Ekstrak Rosela (Hibiscus sabdariffa) dan Ciplukan (Physalis angulata). Institut Pertanian Bogor. Bogor.