CHHATTISGARH SWAMI VIVEKANAND … Chhattisgarh Swami Vivekanand Technical University Semester: 1st Branch: B. Pharmacy Subject: Pharmaceutics-I (Introduction to Pharmaceutics) Code

1

Chhattisgarh Swami Vivekanand Technical University B. Pharmacy First Year

FIRST SEMESTER, (New) from 2012 – 13

S.No. Subject

Code No. Board of Studies

Subject

Periods Per Week

Scheme of Examination Total

Marks

Credit= L+[T+P]

/2 Theory/Practical

L T P ESE CT TA

1 341116(41) Pharmacy Pharmaceutics-I (Introduction to Pharmaceutics) 4 1 - 70 20 10 100 5

2 341117(41) Pharmacy Pharmaceutical Chemistry- I (Inorganic) 4 1 - 70 20 10 100 5

3 341118(41) Pharmacy Pharmacognosy- I 4 1 - 70 20 10 100 5

4 341119(41) Pharmacy Anatomy, Physiology and Health Education- I ( APHE-I) 4 1 - 70 20 10 100 5

5 341110(41) Pharmacy Pharmaceutical Chemistry- II (Organic Chemistry- 1) 4 1 - 70 20 10 100 5

6 341126(41) Pharmacy Pharmaceutics-I (Introduction to Pharmaceutics) Practical - - 3 60 - 40 100 2

7 341127(41) Pharmacy Pharmaceutical Chemistry- I (Inorganic) Practical - - 3 60 - 40 100 2

8 341128(41) Pharmacy Pharmacognosy- I Practical - - 3 60 - 40 100 2

9 341129(41) Pharmacy Anatomy Physiology and Health Education- I (APHE-I) Practical

- - 3 60 - 40 100 2

10 341120(41) Pharmacy Workshop - - 3 60 - 40 100 2 TOTAL 20 5 15 650 100 250 1000 35

Min. Pass Marks: (A) Theory ESE & TA+CT (Combined): 50%, (B) Practical ESE & TA (Combined ): 50%

L- Lecture, T- Tutorial, P- Practical, ESE- End Semester Exam, TA - Teacher's Assessment

www.Pharmainfo.Net

www.Pharmainfo.Net

2

Chhattisgarh Swami Vivekanand Technical University

Semester: 1st Branch: B. Pharmacy

Subject: Pharmaceutics-I (Introduction to Pharmaceutics) Code: 341116(41)

Total Theory Periods: 40 Total Tut. Periods: 12

Total Marks in End Semester Examination: 70

Minimum number of class tests to be conducted: 2

Module: 1 (8 Hrs.)

1.1. Evolution of Pharmacy and Pharmaceutical Literature: History and scope of Pharmacy, Historical background and importance of Indian Pharmacopoeia, British Pharmacopoeia and United State Pharmacopoeia. Introduction and classification of pharmaceutical dosage form.

1.2. Pharmacopoeial Preparations: Principles and methods of preparation of aromatic waters, spirits, elixirs, linctuses, solutions, inhalations.

Module: 2 (8 Hrs.) 2.1. Prescription: Various parts of prescription and their functions, handling of prescriptions, sources of

errors, care required in dispensing procedures including labelling of dispensed products. Preliminary knowledge of important Latin terms used in prescriptions and their translation into English.

2.2 Incompatibilities: Definition of incompatibility, Types of incompatibility (Physical, Chemical and Therapeutic), Study of prescriptions containing incompatibilities, correction and dispensing methods.

Module: 3 (8 Hrs.)

3.1. Principles and procedures of dispensing prescriptions: Principles involved and procedures adopted in dispensing of liquid preparations such as mixtures, suspensions, emulsions, lotions, and liniments; semisolid preparations such as ointments, creams, pastes, jellies and suppositories; solid dosage forms such as powders, capsules, effervescent powders, tablet triturates and lozenges.

Module: 4 (8 Hrs.)

4.1. Pharmaceutical calculations and metrology: Metric and Imperial systems of weights and measures used in prescriptions, Posology, Calculations of doses for infants, children, and elderly patients; reducing and enlarging of formulae; percentage of solutions; allegation method; proof spirits; calculations involving alcohol dilutions.

4.2. Routes of drug administration. Classification of dosage forms.

Module: 5 (8 Hrs.)

5.1. Galenicals: Principles and methods of extraction, preparation of infusions, decoctions, tinctures, liquid, soft and dry extracts.

Text Books/Reference Books (Latest Edition)

1. Ansel, H C, Introduction to Pharmaceutical Dosage Forms, K M Varghese & Co., Bombay. 2. D. K. Tripathi, Introduction to Pharmaceutics (Theory and Practice), Jaypee Brothers Medical

Publisher, Pvt. Ltd., New Delhi. 3. A.R. Gennaro, Remington’s “The Science and practice of Pharmacy”, Lippincot, Williams and

Wilkins, Philadelphia. 4. M.E. Aulton, “Pharmaceutics-The science of doses form design”, Churchill Livingstone, London. 5. Banker and Rhodes, Modern Pharmaceutics. Marcel Dekker Inc. NY. 6. Kibbe, “Hand book of Pharmaceutical Excipients., Pharmaceutical Press, London. 7. N. K. Jain, Text Book of Professional Pharmacy, CBS Publishers & Distributors. New Delhi. 8. B. M. Mithal, Text Book of Pharmaceutical Formulation. 9. Loyd. V. Allen, Jr. Nicholas, G. Popovich, Howard C. Ansel, Pharmaceutical Dosage Forms & Drug

Delivery System. 10. Bentley, E.A. Rawlins. Textbook of Pharmaceutics.

www.Pharmainfo.Net

www.Pharmainfo.Net

3



Subject: Pharmaceutical Chemistry- I (Inorganic) Code: 341117(41)




Module: 1 (8 Hrs.) 1.1 An outline of methods of preparation, uses, sources, of impurities, test for purity and identity including

limit tests for iron, arsenic, lead, heavy metals, chloride, sulphate and special tests if any, of the following classes of inorganic pharmaceuticals listed in Indian Pharmacopoeia.

Module: 2 (8 Hrs.) 2.1 Acids and Bases: Buffers, Water. 2.2 Gastrointestinal Agents: Acidifying agents, Antacids, Protectives, and Absorbents, Cathartics.

Module: 3 (8 Hrs.) 3.1 Major Intra and Extra Cellular Electrolytes: Physiological cations, Electrolytes used for replacement

therapy, acid-base balance and combination therapy. 3.2 Essential and Trace Elements: Transition elements and their compounds of pharmaceutical

importance, Iron and haematinics, Mineral supplements. 3.3 Cationic and anionic components of inorganic drugs useful for systemic effects. Module: 4 (8 Hrs.) 4.1 Topical Agents: Protectives, Astringents and Anti-infectives. 4.2 Gases and Vapours: Oxygen, Anaesthetics and respiratory stimulants. 4.3 Dental Products: Dentifrices, anti-caries agents. Module: 5 (8 Hrs.) 5.1 Complexing and chelating agents used in therapy. 5.2 Miscellaneous Agents: Sclerosing agents, expectorants, emetics, poisons and antidotes, sedatives

etc., pharmaceutical aids used in pharmaceutical industry antioxidants, preservatives, diluents, excipients, suspending agents, colorants, filter aids, adsorbents etc.

5.3 Inorganic radio-pharmaceuticals: Nuclear radiopharmaceuticals, units of activity, measurement of activity, clinical applications and dosage, hazards and precautions.


1. Block J H, Roche E, Soine T 0 and Wilson C 0, Inorganic Medicinal and Pharmaceutical Chemistry, Lea and Febiger, Philadelphia, P A. Brey W S,

2. Diseher L A, Modem Inorganic Pharmaceutical Chemistry. Eliel E L, 3. Chatwak, Inorganic Pharmaceutical Chemistry 4. Md. Ali, Inorganic Pharmaceutical Chemistry 5. Choudary and Gurbani, Inorganic Pharmaceutical Chemistry 6. Kadri and Kadri, Inorganic Pharmaceutical Chemistry 7. S.N. Pande, Inorganic Pharmaceutical Chemistry 8. David G. Watson, Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical

Chemists, Elsevier Health Sciences, 2012 9. Alfonso R. Gennaro (Editor), Remington: The Science and Practice of Pharmacy, 19th edition (Two

Vols.), Williams & Wilkins, 1995

www.Pharmainfo.Net

www.Pharmainfo.Net

4



Subject: Pharmacognosy- I Code: 341118(41)

Total Theory Periods: 40 Total Tut. Periods: 12 Total Marks in End Semester Examination: 70


Module: 1 (6 Hrs.)

1.1 Introduction: A brief Introduction to plant kingdom, plant cell and tissues. Definition, history, scope and

development of Pharmacognosy..

Module: 2 (6 Hrs.)

2.1 Classification of drugs: Alphabetical, morphological, taxonomical, chemical, pharmacological and other

novel methods of classification of drugs.

2.2 Sources of drugs: Biological, mineral and marine as sources of drugs.

Module: 3 (8 Hrs.)

3.1 Study of the following families with special reference to medicinally important plants–Apocynacae (Vinca, Sarpgandha), Solanaceae (Belladona, Datura, Tobacco), Umbelliferae (Fennel, Coriander, Carraway), Leguminosae (Senna, Fenugreek, Liquorice), Rubiaceae (Cinchona), Liliaceae (Onion, Asparagus, Aloe), Graminae (Cynodon dactylon, Ergot), Papaveraceae (Poppy).

Module: 4 (12 Hrs.)

4.1 Introduction: An introduction to active constituents of plants, their classification and properties.

4.2 Quality control of crude drugs: Adulteration of crude drugs and their detection by organoleptic, microscopic, physical, chemical and biological methods and properties.

Module: 5 (8 Hrs.)

5.1 Natural Fibres: Study of fibres used in pharmacy such as fibres, wool, glass wool, and asbestos.

5.2 Pharmaceutical aids: Definition, classification and study of some pharmaceutical aids of different category (Turmeric, saffron, Arachis oil, Agar, Guar gum, Acacia, Honey, Musk, Isabgol, Pectin, Starch, Tragacanth, Bees wax, Castor oil, Cocoa butter, Linseed oil and Wool fat).


1. C. K. Kokate, A.P.Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune. 2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier. 3. T.E. Wallis Text Book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, Darya Ganj. 4. V.E. Tyler, L.R. Brady & J.E. Robbers, Text Book of Pharmacognosy, Lea & Febiger, Philadelphia, 5. S.H. Ansari, Essential of Pharmacognosy, Birla Publication, Shahdara, New Delhi. 6. T. E. Wallis Analytical Microscopy, J&A Churchill Limited, London. 7. K.R. Brain and T.D Turner. “The Practical Evaluation of Phyto Pharmaceutical”, Wright,

Scientechnica- Bristol. 8. P, J. Schewer, Marine Natural products, Academic press, London. 9. Mohammed Ali. Pharmacognosy & Phytochemistry,

www.Pharmainfo.Net

www.Pharmainfo.Net

5



Subject: Anatomy, Physiology and Health Education- I (APHE-I) Code: 341119(41)



Minimum number of class tests to be conducted: 2 Module: 1 (8 Hrs.)

1.1. Introduction: A brief introduction to animal kingdom (taxonomical classification), Scope of anatomy and physiology and basic terminology used in these subjects. Structure of cell, its components and their functions.

Module: 2 (8 Hrs.) 2.1. Elementary tissues of the human body: Epithelial, Connective, Muscular and Nervous tissues, their

sub types and characteristics. 2.2. Osseous System: Structure, composition and functions of skeleton, classification of joints, types of

movements of joints, disorders of joints. 2.3. Skeletal Muscles: Gross anatomy and physiology of muscle contraction, physiological properties of

skeletal muscles and their disorders.

Module: 3 (8 Hrs.) 3.1. Haemopoietic System : Composition and functions of blood and its elements, their disorders, blood

groups and their significance, mechanism of coagulation, disorders of platelets and coagulation. 3.2. Lymph and Lymphatic System: Composition, formation and circulation of lymph; disorders of lymph

and lymphatic system. Basic physiology and functions of spleen.

Module: 4 (8 Hrs.) 4.1. Cardiovascular System: Basic anatomy of the heart, physiology, blood vessels and circulation. Basic

understanding of cardiac cycle, heart sounds and electrocardiogram. Brief outline of cardiovascular disorders like hypertension, hypotension, arteriosclerosis, angina, myocardial infarction, congestive cardiac failure and cardiac arrhythmias.

Module: 5 (8 Hrs.) 5.1. Digestive System: Gross anatomy of the gastro-intestinal tract, functions of its different parts including

those of liver, pancreas and gall bladder, various gastrointestinal secretions and their role in the absorption and digestion of food. Disorders of digestive system.

Text Books/Reference Books (Latest Edition):

1. Ross & Willson Anatomy & Physiology in Health and Illness, Churchill Living Stone. 2. G.J., Tortora, S.R. Grabowski & N.P. Anagnodokos, Principle of Anatomy & Physiology, Willey. 3. S.K. Choudhury Concise Medical Physiology, New Central Book Agency, Latest Ed. 4. Guyton A.C, Hall J. E. W. B. Saunders Company, Text Book of Medical Physiology. 5. C. C. Chatterjee, Human Physiology (Vol-I & II), Medical Allied Agency, Latest Ed.

www.Pharmainfo.Net

www.Pharmainfo.Net

6


Semester: 1st

Branch: B. Pharmacy

Subject: Pharmaceutical Chemistry II (Organic chemistry -1) Code: 341110(41)




Module: 1 (8 Hrs.) Structure and Bonding, Atomic orbital, Hybridizations, Types of bonds, Bond lengths and bond angles, bond energy :van-der Waals interactions, inclusion compounds, charge transfer complex.

Module: 2 (8 Hrs.)

Types of Reagent, Electrophiles and nucleophiles. Types of organic reactions (Substitution, Addition and elimination reaction). Electron Displacement Effects: Inductive Effect, Mesomeric Effect, Electromeric Effect, Effect of Hyperconjugation. Homolytic bond fission, Heterolytic bond fission.

Module: 3 (8 Hrs.)

General rules for I.U.P.A.C. Nomenclature of Organic compounds. Structure, Occurrence and Stability of Carbonium ions, Carbanion ions and Free radicals, Energy consideration.

Module: 4 (8 Hrs.)

Stereochemistry -I Concept of isomerism, types of isomerism, optical isomerism, elements of symmetry, molecular chirallity, enantiomers, stereogenic centers, optical activity, properties of enantiomers, chiral and achiral molecules with two stereogenic centres, distereoisomers, mesocompounds, resolution of enantiomers, inversion, retention and racemization. Relative and absolute configurations, sequence rules, D & L , R & S systems of nomenclature.

Module: 5 (8 Hrs.)

Stereochemistry - II Nomenclature E and Z system, geometrical isomerism in alicyclic compounds. Conformation, conformational analysis of ethane and n-butane. Conformations of cyclohexanes, axial and equatorial bonds, Newman projection and Saw horse formulae, Fischer and Flying wedge formulae.


1. A guide book to mechanism in Organic chemistry (Orient-Longmens)- Peter Sykes 2. Organic reaction mechanism (Benjamin) R. Breslow 3. Mechanism and structure in Organic chemistry (Holt Reinh.) B. S. Gould. 4. Organic chemistry(McGraw-Hill)Hendrikson, Cram and Hammond. 5. Basic principles of Organic chemistry (Benjamin) J. D.Roberts and M. C. Caserio. 6. Reactive Intermediates in Organic chemistry (John Wiley) N. S. Issacs. 7. Stereochemistry of Carbon compounds. (McGraw-Hill) E.L.Eliel 8. Singh Harkishan and Kapoor, V.K., Organic Pharmaceutical Chemistry, Vallabh Prakashan, Delhi. 9. Morrison T R and Boyd R N, Organic Chemistry, Prentice Hall of India, Private limited, New Delhi.

10. Finar I L, Organic Chemistry, Vol. II ELBS/Longman, London. Foye W C, 11. O.P Agarwal, Reaction and Reagents.

www.Pharmainfo.Net

www.Pharmainfo.Net

7



Subject: Pharmaceutics-I (Introduction to Pharmaceutics) Lab. Code: 341126(41)

Total Practical Periods: 36


List of Practical (A minimum of 20 experiments shall be conducted)

1. Study Indian Pharmacopoeia, British Pharmacopoeia, United States Pharmacopoeia. 2. To prepare and submit Camphor Water I.P. 3. To prepare and submit Chloroform Water I.P. 4. To prepare and submit Conc. Anise Water I.P. 5. To prepare and submit Aqueous Iodine Solution I.P. 6. To prepare and submit Weak Iodine Solution I.P. 7. To prepare and submit Strong Iodine Solution I.P. 8. To prepare and submit Simple Syrup I.P. and U.S.P 9. To prepare and submit Chloroform Spirit I.P. 10. To prepare Benzaldehyde spirit. 11. To prepare surgical spirit. 12. To prepare and submit Simple elixir I.P. 13. To prepare and submit Calamine Lotion I.P. 14. To prepare and submit Calamine Lotion USP, oily. 15. To prepare and submit Liquid Paraffin Emulsion I.P 16. To prepare and submit castor oil emulsion. I.P. 17. To prepare and submit Tragacanth Mucilage I.P. 18. To prepare and submit Milk of Magnesia I.P 19. To prepare and submit Bentonite Magma U.S.P. 20. To prepare and submit Borax Glycerin I.P. 21. To prepare and submit Simple Tinctures I.P. 22. To prepare and submit orange / lemon Tincture I.P. 23. To prepare and submit salicylic acid lotion BPC. 24. To prepare and submit liquid paraffin & magnesium hydroxide emulsion BPC. 25. To prepare and submit lubricating gel. 26. To prepare and submit Peppermint water IP. 27. To prepare and submit soap liniment. 28. To prepare and submit sodium alginate jelly. 29. To prepare and supply NaCl solution. 30. To prepare and supply benzoic acid solution. 31. To prepare and supply Sodium bi carbonate ear drop. 32. To prepare and supply Boric acid ear drop. 33. To prepare and supply phenol ear drop. 34. To prepare camphor liniment. 35. To prepare Turpentine liniment. 36. To prepare soap liniment. 37. To prepare calamine lotion. 38. To prepare cetrimide lotion. 39. To prepare gentian violet lotion. 40. To prepare simple ointment. 41. To prepare calamine ointment. 42. To prepare Ichthammol ointment. 43. To prepare chloral hydrate enema. 44. To prepare soap enema. 45. To prepare compound zinc paste.

www.Pharmainfo.Net

www.Pharmainfo.Net

8

46. To prepare NaCl mouthwash compound. 47. To prepare aqueous calamine cream. 48. To prepare vanishing cream. 49. Aligation problems


1. Indian Pharmacopoeia, British Pharmacopoeia, United State Pharmacopoeia. 2. D. K. Tripathi, Introduction to Pharmaceutics (Theory and Practice), Jaypee Brothers Medical

Publisher, Pvt. Ltd., New Delhi. 3. A.R. Gennaro, Remington’s “The Science and practice of Pharmacy”, Lippincot, Wiliams and

Wilkins, Philadelphia. 4. M.E. Aulton, “Pharmaceutics-The science of doses form design”, Churchill Livingstone, London. 5. Banker and Rhodes, Modern Pharmaceutics. Marcel Dekker Inc. NY. 6. Kibbe, “Hand book of Pharmaceutical Excipients., Pharmaceutical Press, London. 7. A. Martin, J Swarbrick, A Cammarata. Physical Pharmacy. 8. N. K. Jain, Text Book of Professional Pharmacy, CBS Publishers & Distributors. New Delhi. 9. N.K. Jain, Pharmaceutical product development, CBS Publishers & Distributors. New Delhi. 10. B. M. Mithal, Text Book of Pharmaceutical Formulation. 11. Loyd. V. Allen, Jr. Nicholas, G. Popovich, Howard C. Ansel, Pharmaceutical Dosage Forms & Drug

Delivery System. 12. Bentley, E.A. Rawlins. Textbook of Pharmaceutics.

www.Pharmainfo.Net

www.Pharmainfo.Net

9



Subject: Pharmaceutical Chemistry- I (Inorganic) Lab. Code: 341127(41)




1. Limit test for chlorides in some Pharmacopoeial compounds including soluble, insoluble and colored substances.

2. Limit test for Sulphates in some Pharmacopoeial compounds including soluble, insoluble and colored substances.

3. Limit test for iron in some Pharmacopoeial compounds including soluble and insoluble substances. 4. Limit test for lead in some Pharmacopoeial compounds including soluble and insoluble substances. 5. Limit test for arsenic. 6. Identification and qualitative tests for cations & anions of given sample of Ammonium chloride. 7. Identification and qualitative tests for cations & anions of given sample of Magnesium sulphate. 8. Identification and qualitative tests for cations & anions of given sample of Ferrous Sulphate. 9. Identification and qualitative tests for cations & anions of given sample of Calcium carbonate. 10. Identification and qualitative tests for cations & anions of given sample of Zinc chloride. 11. Identification and qualitative tests for cations & anions of given sample of Ammonium sulphate. 12. Identification and qualitative tests for cations & anions of given sample of Zinc sulphate. 13. Preparation and identification tests of Ammonium hydroxide. 14. Preparation and identification tests of Alum. 15. Preparation and identification tests of Aluminium hydroxide. 16. Preparation and identification tests of Disodium hydrogen citrate. 17. Preparation and testing of purified water.

Text Books/ Reference Books (Latest Edition):

1. Block, Roche, Soine, Wilson, Inorganic Medicinal & Pharmaceutical Chemistry, Varghese Publishing House, Bombay.

2. Bentley & Driver, A Text Book of Pharmaceutical Chemistry, Oxford Medical Publication. 3. G. R. Chatwal, Pharmaceutical Chemistry- I (Inorganic), Himalaya Publishing House, New Delhi. 4. Pharmacopoeia of India, Ministry of Health, Govt. of India, New Delhi. 5. David G. Watson, Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical

Chemists, Elsevier Health Sciences, 2012 6. Alfonso R. Gennaro (Editor), Remington: The Science and Practice of Pharmacy, 19th edition (Two

Vols.), Williams & Wilkins, 1995

www.Pharmainfo.Net

www.Pharmainfo.Net

10

Chhattisgarh Swami Vivekanand Technical University Semester: 1st Branch: B. Pharmacy

Subject: Pharmacognosy-I Lab. Code: 341128(41)




1. Study of different types of microscopes, camera lucida, micrometers.

2. Determination of leaf constants such as stomatal index, stomatal number, vein-islet number, vein-termination number and palisade ratio, at least one drug (Senna, Datura, Vinca, Belladona).

3. Preparation of herbarium sheets of plants studied in Plant taxonomy

4. Perform macroscopic examination (Morphology and Organoleptic) of some drugs mentioned in theory (at least ten drugs).

5. Perform microscopic measurements of cells and Cell contents:

a. Starch grains- Rice, Potato and Maize

b. Calcium oxalate crystals- Liquorice, Cinchona, Belladona, Onion

c. Phloem fibers- Vinca, Sarpgandha, Cinchona

6. Perform microscopic examination of powder characteristics of some crude drugs, at least two drugs (Sarpgandha, Datura, Senna, Fenugreek, Cinchona).

7. Perform microscopic examination of Umbelliferous fruits (Fennel, Coriander, Carraway),

8. Perform General chemical tests for Carbohydrates, Lipids and Proteins.

9. Perform physical and chemical study of carbohydrate fibres (Cotton, Jute, Flax, Viscose, and Rayon).

10. Perform physical and chemical study of pharmaceutical aids, at least three drugs (Turmeric, Arachis oil, Agar, Acacia, Honey, Isabgol, Tragacanth, Bees wax, Wool fat).


1. C. K. Kokate, A.P.Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune. 2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier. 3. T.E. Wallis Text Book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, Darya Ganj. 4. V.E. Tyler, L.R. Brady & J.E. Robbers, Text Book of Pharmacognosy, Lea & Febiger, Philadelphia, 5. S.H. Ansari, Essential of Pharmacognosy, Birla Publication, Shahdara, New Delhi. 6. T. E. Wallis Analytical Microscopy, J&A Churchill Limited, London. 7. K.R. Brain and T.D Turner. “The Practical Evaluation of Phyto Pharmaceutical”, Wright, Scientechnica-

Bristol.

www.Pharmainfo.Net

www.Pharmainfo.Net

11


Subject: Anatomy Physiology and Health Education-I Lab. (APHE-I) Lab. Code: 341129(41)




1. Determine RBC count of own blood. 2. Determine WBC count of own blood. 3. Determine differential WBC count of own blood. 4. Determine platelets count of own blood. 5. Determine hemoglobin count of own blood. 6. Determine bleeding and clotting time of own blood. 7. Determine blood group of own blood. 8. Study of epithelial, connective, muscular and nervous tissue using slide. 9. Study human skeletal system with the help of chart, model and histological slides. 10. Study of human cardiovascular system with the help of chart, model and histological slides. 11. Record of blood pressure, blood temperature and pulse rate. 12. To understand ECG, PQRST waves and their significance. 13. Study of human digestive system with the help of chart, model and histological slides. 14. Study of lymphatic system with the help of chart, model and histological slides.


1. Ross & Willson Anatomy & Physiology in Health and Illness, Churchill Living Stone. 2. G.J., Tortora, S.R. Grabowski & N.P. Anagnodokos, Principle of Anatomy & Physiology, Willey. 3. S.K. Choudhury Concise Medical Physiology, New Central Book Agency, Latest Ed. 4. Guyton A.C, Hall J. E. W. B. Saunders Company, Text Book of Medical Physiology. 5. C. C. Chatterjee, Human Physiology (Vol-I & II), Medical Allied Agency, Latest Ed.

www.Pharmainfo.Net

www.Pharmainfo.Net

12


Subject: Workshop Code: 341120(41)



1. Handling of glassware and Instruments (along with different type of pipettes and burettes). 2. Study and calibration of glasswares, weight box and fractional weight box. 3. Different weighing methods and working of analytical, physical balance and use of rider. 4. Washing and sterilization of laboratory glassware’s 5. Preparation of general laboratory reagent and distilled water 6. Preparations of an exhibit file of any one type of dosage form. 7. Brief study of different pharmacopeias (IP,BP,USP,NF,BPC) 8. Study of periodic table


1. Vogel's Textbook of Practical Organic Chemistry (5th Edition) 2. Beckett’s Practical Pharmaceutical Chemistry, Part-I & II (4th Edition) 3. Indian Pharmacopoeia 4. National Formulary

www.Pharmainfo.Net

www.Pharmainfo.Net

1

Chhattisgarh Swami Vivekanand Technical University B. Pharmacy First Year,

SECOND SEMESTER, (New) from 2012 - 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week

Scheme of Examination

Total Marks

Credit=L+[T+P

]/2 Theory

L T P ESE

CT TA

1 341216(41) Pharmacy Pharmaceutics- II (Hospital and Community Pharmacy) 4 1 - 70 20 10 100 5

2 341217(41) Pharmacy Anatomy, Physiology and Health Education- II ( APHE-II) 4 1 - 70 20 10 100 5

3 341218(41) Pharmacy Pharmaceutics- III Drug Store and Business Management (DSBM) 4 1 - 70 20 10 100 5

4 341219(41) Pharmacy Pharmaceutical Chemistry-III (Organic Chemistry-2) 4 1 - 70 20 10 100 5

5 341210(41) Pharmacy English Communication - I 4 1 - 70 20 10 100 5

6 341226(41) Pharmacy Pharmaceutics- II (Hospital & Community Pharmacy) Practical - - 3 60 - 40 100 2

7 341227(41) Pharmacy Anatomy, Physiology and Health Education- II ( APHE-II) Practical - - 3 60 - 40 100 2

8 341229(41) Pharmacy Pharmaceutical Chemistry- III (Organic Chemistry-2) Practical - - 3 60 - 40 100 2

9 341220(41) Pharmacy English Communication-I Practical - - 3 60 - 40 100 2

10 341228(41) Pharmacy Field Work - - 3 60 - 40 100 2 TOTAL 20 5 15 650 100 250 1000 35

Min. Pass Marks: (A) Theory ESE & TA+CT (Combined): 50%, (B) Practical ESE & TA (Combined): 50%

L- Lecture, T- Tutorial, P- Practical, ESE- End Semester Exam, TA- Teacher's Assessment

www.Pharmainfo.Net

www.Pharmainfo.Net

2


Semester: 2nd Branch: B. Pharmacy

Subject: Pharmaceutics- II (Hospital and Community Pharmacy) Code: 341216(41)



Minimum number of class tests to be conducted: 2 Module: 1 (8 Hrs.) 1.1. Organization and Structure: Organization of a hospital and hospital pharmacy, responsibilities of a

hospital pharmacist, Pharmacy and Therapeutic Committee, budget preparation and implementation. 1.2. Hospital Formulary: Contents, preparation and revision of hospital formulary. Module: 2 (8 Hrs.) 2.1. Drug Store Management and Inventory Control: 2.1.1. Organization of drug store. Types of materials stocked, storage conditions. 2.1.2. Purchase and Inventory Control principles, purchase procedures, Purchase order, Procurement and

stocking. 2.2. Drug distribution System in Hospitals: 2.2.1. Outpatient dispensing, methods adopted, mandatory labeling of drugs. 2.2.2. Dispensing of drugs to in-patients. Type of drug distribution systems. Changing policy,. Module: 3 (8 Hrs.) 3.1. Central Sterile Supply and their Management: Types of materials for sterilization, packing of materials

prior to sterilization, sterilization equipment, Supply of sterile materials. 3.2. Manufacture of Sterile and Non-sterile Products: Policy making of manufacturable items, demand

and costing, personnel requirements, manufacturing practice, master formula card, production control, manufacturing records.

Module: 4 (8 Hrs.) 4.1. Surgical Products: Definition, Primary wound dressing, absorbents, surgical cotton, surgical gauzes,

bandages, adhesive tape, protective cellulosic hemostastics, dressings, absorbable and non-absorbable sutures, ligatures and catguts.

4.2. Drug Information Services: Sources‟ of information on drugs, disease, treatment schedule, procurement of information, computerized services (e.g. MEDLINE), retrieval of information, medication error.

Module: 5 (8 Hrs.) 5.1. Records and Reports: Prescription filling, drug profile, patient medication profile, cases on drug

interaction and adverse reactions, idiosyncratic cases. 5.2 Community Pharmacy: Organization and structure of retail and whole sale drug store-types of drug store and design, legal requirements for establishment, maintenance and drug store-dispensing of proprietary products, maintenance of records of retail and whole sale, patient counseling, role of pharmacist in community health care and education. Text Books/Reference Books (Latest Edition): 1. H.S Merchant and J. S. Qadry, Text Book of Hospital Pharmacy, B.S. Shah Prakashan, Ahmedabad. 2. P. Nanda & R.K. Khar, Text book of Hospital & Clinical Pharmacy, Birla Publications, New Delhi. 3. P.C. Dandiya & M. Mathur, A text book of Hospital & Clinical Pharmacy, Vallabh Prakashan, New Delhi. 4. A.A. Siddiqui & M. Ali, Hospital & Clinical Pharmacy, CBS Publishers, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

3

Chhattisgarh Swami Vivekanand Technical University Semester: 2nd

Branch: B. Pharmacy Subject: Anatomy, Physiology and Health Education-II (APHE-II) Code: 341217(41) Total Theory Periods: 40 Total Tut. Periods: 12 Total Marks in End Semester Examination: 70 Minimum number of class tests to be conducted: 2

Module: 1 (8 Hrs.)

1.1. Central Nervous System: Functions of different parts of brain and spinal cord. Neurohumoral

transmission in the central nervous system, reflex action, electroencephalogram, specialized functions of

the brain, cranial nerves & their functions.

Module: 2 (8 Hrs.)

2.1. Autonomic Nervous System: Physiology & functions of the autonomic nervous system. Mechanism of

neurohumoral transmission in the Autonomic Nervous System.

2.2. Urinary System: Various parts, structures and functions of the kidney and urinary tract. Physiology of

urine formation, acid-base balance. Functional disorders of the urinary system.

Module: 3 (8 Hrs.)

3.1. Reproductive System: Male and female reproductive systems and their hormones, physiology of

menstruation and fertilization. Oogenesis, spermatogenesis and organogenesis. Pregnancy, its

maintenance and parturition.

3.2. Endocrine System: Basic anatomy and physiology of Pituitary, Thyroid, Parathyroid, Adrenals,

Pancreas Testes and Ovary, their hormones and functions. Diseases in hypo and hyper secretions.

Module: 4 (8 Hrs.)

4.1. Respiratory system: Anatomy of respiratory organs and its functions, respiration mechanism and

regulation of respiration, respiratory volumes and vital capacity.

4.2. Sense Organs: Basic anatomy and physiology of the eye (vision), ear (hearing and balance), taste

buds, nose (smell) and skin (superficial receptors).

Module: 5 (8 Hrs.)

5.1. Health Education: Brief outline of communicable diseases, Their causative agents, Mode of

transmission and Prevention - Chicken pox, Measles, Influenza, Diphtheria, Whooping, cough,

Tuberculosis, Poliomyelitis, Hepatitis, Cholera, Typhoid, Food poisoning, Helminthiasis, Malaria,

Filariasis, Rabies, Trachoma, Tetanus, Syphilis, Gonorrhoea and AIDS.

Text Books/Reference Books(Latest Edition):

1. Ross & Willson, Anatomy and Physiology in Health & Illness, , Churchill Living Stone.

2. Tortora G.J., & Anagnodokos N.P. Principles of Anatomy & Physiology,

3. Guyton A C, Hall JE., Saunders W.B., Company Text book of Medical Physiology,

4. Chhatterjee C .C. ,Human Physiology, Medical Allied Agency, Calcutta.

www.Pharmainfo.Net

www.Pharmainfo.Net

4



Subject: Pharmaceutics- III Code: 341218(41)

Drug Store and Business Management ( DSBM) Total Tut. Periods: 12 Total Theory Periods: 40



Module: 1 (8 Hrs.)

1.1. Concept of Management: Principles of Management (Co-ordination, Communication, Motivation,

Decision making, leadership, innovation, creativity, delegation of authority/responsibility and record

keeping) Identification of Key points to give maximum thrust for development and perfection.

1.2. Types of Management: Administrative management (Planning, Organizing, Staffing, Directing and

Controlling), Entrepreneurship development, Operative Management (Personnel, Materials, Production,

Financial, Marketing, Time/space, Margin/Morale).

Module: 2 (8 Hrs.)

2.1. Economics: Principles of economics with special reference to the laws of demand and supply, demand

schedule, demand curves, labor welfare, general principles of insurance, inland and foreign trade,

procedure of exporting and importing goods.

Module: 3 (8 Hrs.)

4.1. Pharmaceutical Marketing: Function, buying, selling, transportation, storage, finance, feedback,

information, channels of distribution, wholesale, retail, departmental store, multiple shop and mail order

business.

Module: 4 (8 Hrs.)

4.1. Salesmanship: Principles of sales promotion, advertising, ethics of sales, merchandising, literature &

detailing. Recruitment, training, evaluation and compensation to the pharmacist.

4.2. Market research: Prerequisites, Basic information services.

Module: 5 (8 Hrs.)

5.1. Materials management: A brief exposure to the basic principles of materials management, purchase,

stores and inventory control and evaluation of materials management.

5.2. Production Management: A brief exposure of the different aspects of production management (Visible

& Invisible) inputs, methodology of activities, performance evaluation techniques, Process-flow, process

management and maintenance management.


1. R. Saxena,“Marketing Management”, Tata McGraw Hill.

2. M.J. Etazel, B. J. Walker and W. J. Stanton, Text Book of Marketing,Tata McGraw Hill.

www.Pharmainfo.Net

www.Pharmainfo.Net

5



Subject: Pharmaceutical Chemistry III (Organic Chemistry-2) Code: 341219(41)




Module: 1 (8 Hrs.)

Hydrocarbons Alkanes: Nomenclature, General methods of preparation, physical properties, combustion, Free radical substitution reactions (Chain reaction: halogenation). Alkenes: Nomenclature, general methods of preparation, Electrophilic addition reactions, Markovnikov rule, Antimarkovnikov rule, Catalytic hydrogenation, Oxidation, Combustion.

Module: 2 (8 Hrs.)

Alkynes: Nomenclature, general methods of preparation, Electronegativity of sphybridized carbon and acidity of acetylene, Substitution and Addition reactions. Alcohols: Nomenclature, General methods of preparation, Physical properties (Hydrogen bonding) Nucleophilic substitution reactions and Elimination reaction of alcohols, Saytzeff rule

Module: 3 (8 Hrs.)

Carbonyls- General methods of preparation, their synthesis, and physical and chemical properties. Aldehydes and Ketones: General methods of preparation, acidity of α-hydrogen, Nucleophilic addition reactions, Aldol condensation reaction, Cannizzaro reaction, Clemmensen reduction

Module: 4 (8 Hrs.)

Carboxylic acids: Nomenclature, general methods of preparation, physical and chemical properties of Acid halides and anhydrides, Effect of substituent on acidity of Acid halides and anhydrides.

Module: 5 (8 Hrs.)

Catalytic hydrogenation, Dehydrogenation, Electrolytic reaction, Sigmatropic reaction

List of Text Books/Reference Books (Latest Edition):

1. Morrison & Boyd, Organic Chemistry, Pearson Education.

2. Bahl & Bahl, Advanced Organic Chemistry, S.Chand Publisher, New Delhi.

3. I.L. Finar Organic Chemistry Vol. I & II, , Pearson Education.

4. Bentley & Driver, Text of Pharmaceutical Chemistry, Oxford University Press, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

6


Branch: Pharmacy Subject: English Communication Code: 341210(41) Total Theory Periods: 40 Total Tut. Periods: 12 Total Marks in End Semester Examination: 70 Minimum number of class tests to be conducted: 2

Module: 1 (8 Hrs.)

1.1. Communicative Grammar: Time, tense and aspect; Verbs of states and events; Statements, questions

and responses; Omission of information; Expressing emotion and attitude, hope, pleasure,

disappointment, regret, approval, surprise.

Module: 2 (8 Hrs.)

2.1 Communication: Verbal and non-verbal spoken and written; Language functions descriptive, expressive

and social; to inform, enquire, attract, influence, regulate and entertain; Bias-free and plain English;

Formal and informal style.

Module: 3 (8 Hrs.)

3.1. The Sounds of English: Length of vowels-Long vowels as in feel, card, court, food and first

respectively; Short vowels as in pen, bag, and sun respectively; Consonants as in fine, vast, thought,

them, song, zoo, shame, pleasure and judge respectively; Friendly communication-greeting, farewells,

introduction, thanks, apologies, regrets, good wishes congratulations, condolences, offers.

Module: 4 (8 Hrs.)

4.1. Doing things with words: To ask for information, help, permission; to instruct, command, request,

accept, refuse, prohibit, persuade, and promise.

Module: 5 (8 Hrs.)

5.1. Writing: Selecting material for expository, descriptive , and argumentative pieces, business letters;

formal report; summarizing and abstracting ; expressing ideas within a restricted word limit; paragraph

division; the introduction and the conclusion; listing reference material; use of charts, graphs and

tables; punctuation and spelling; semantics of connectives, modifiers and modals; variety in sentences

and paragraphs.

Text Books / Reference Books (Latest Edition):

1. S R Inthira & V Saraswathi “ Enrich your English – a) Communication skills b) Academic skills “ Publisher

CIEFL & OUP

2. R.C. Sharma and K.Mohan , “Business Correspondence and Report Writing “ , Tata McGraw Hill , New

Delhi , 1994

www.Pharmainfo.Net

www.Pharmainfo.Net

7

3. L.Gartside , “Model Business Letters” , Pitman , London , 1992

4. Longman , “Longman Dictionary of Contemporary English” ( or „Oxford Advanced Learner‟s Dictionary of

Current English‟ , OUP , 1998.

5. Maxwell Nurnberg and Rosenblum Morris , “All About Words” , General Book Depot, New Delhi , 1995

6. Greenbaum, Greenbaum Sidney, A Student's Grammar of the English Language, Pearson Education

India, 2005

7. Douglas Biber, Susan Conrad, Geoffrey N. Leech, Longman Student Grammar of Spoken and Written

English: Workbook, Volume 1-4, Longman, 2002

8. Geoffrey N. Leech, Meaning And The English Verb, Pearson/Longman, 2004

9. Saraswati, English Language Teaching:Principles&Practice, Orient Blackswan, 2004

10. Percival Christopher Wren, H. Martin, High School English Grammar and Composition, S.Chand &

Company, 1995

11. Dr. B.B.Jain, Learn To Write Correct English (Eng.-Hindi), Upkar Prakashan, 2010

12. Kumkum Bhardwaj, Professional Communication, I. K. International Pvt Ltd, 2008

13. Jayanthi Dakshina Murthy, Correct Your Common Errors In English, Upkar Prakashan, 2010

14. Raymond Murphy, English Grammar In Use without Answers: A Reference and Practice Book for

Intermediate Students of English, Cambridge University Press, 2004

www.Pharmainfo.Net

www.Pharmainfo.Net

8

Chhattisgarh Swami Vivekanand Technical University Semester: 2nd Branch: B. Pharmacy

Subject: Pharmaceutics- II (Hospital & Community Pharmacy) Lab. Code: 341226(41)




1. To study the different types of Sterilizers (Autoclave, Hot air oven, membrane filter).

2. To sterilize surgical instruments and surgical dressings.

3. To sterilize syringes, needles and glassware.

4. To sterilize rubber gloves and rubber tubing.

5. To study the use of Computers in hospital for registration of patient in OPD/IPD case history and pre-

operation check list.

6. To study the use of Computer in day information center.

7. To study the use of Computer in prescription filling.

8. To study the use of Computer in documentation of information on day information

9. To study the role of Pharmacist in family planning.

10. To Prepare and submit 100ml (500ml) of 5% w/v Dextrose intravenous infusion I.P.

11. To prepare and submit 100ml(500ml) of 0.9%w/v Sodium chloride intravenous infusion I.P.

12. To prepare and submit 500ml of Compound sodium lactate injection I.P. (Hartmann‟s solution).

13. To prepare and submit 100ml (500ml) of sodium chloride and dextrose injection I.P

14. To prepare and submit 100ml (500ml) of 1.6% w/v sodium chloride hypertonic injection I.P.

15. To prepare and submit simple powder and compound powder.

16. To prepare and submit powder containing small doses.

17. To prepare and submit powder containing liquids.

18. To prepare and submit powder containing liquefiable substances.

19. To prepare and submit powder containing hygroscopic, efflorescent and deliquescent substances.

20. To prepare and submit effervescent granules.

21. To prepare and submit dusting powder.

22. To prepare and submit simple mixture containing soluble substances only.

23. To prepare and submit mixture containing diffusible solids.

24. To prepare and submit mixture containing small doses of potent medicaments.

25. To prepare and submit prescription possessing Physical Incompatibility (Incomplete Solution).

26. To prepare and submit prescription possessing Chemical Incompatibility (Soluble salicylates with

acids-Adjust Incompatibility).

27. To prepare and submit prescription possessing Chemical Incompatibility (soluble salicylates with

ferric salts, soluble benzoates with ferric salts).


1. P. Nanda & R.K. Khar, Text book of Hospital & Clinical Pharmacy, Birla Publications, New Delhi.

2. Dr. A.P. Paradkar, S.B. Gokhale & Mrs. B.A. Bapat, Practical Hospital & Clinical Pharmacy. Mirmal

Prakashan, New Delhi

www.Pharmainfo.Net

www.Pharmainfo.Net

9

Chhattisgarh Swami Vivekanand Technical University Semester: 2nd Branch: B. Pharmacy

Subject: Anatomy Physiology and Health Education-II (APHE-II) Lab. Code: 341227(41)




1. To study human digestive system with help of chart and models and study histology of salivary glands,

esophagus, stomach, pancreas, liver, small intestine, large intestine.

2. To study human urinary system with help of chart and models study histology of nephron, urinary

bladder, ureter

3. To study male and female reproductive system with help of chart and models and study histology of

testes, ductus, epididymis, ovary, uterus, mammary glands.

4. To study brain and spinal cord with help of chart and models and study histology of cerebrum,

cerebellum, spinal cord

5. To study structure and physiology of special senses.

6. To study structure and physiology of Eye.

7. To study structure and physiology of Ear.

8. To study structure and physiology of Skin.

9. To study structure and physiology of Taste buds.

10. To study structure and physiology of Nose.

11. To perform urine analysis for physiological (normal) constituent present in urine sample.

12. To study pathological (abnormal) constituent in the urine sample.

13. To perform quantitative analysis for presence of glucose in urine sample.

14. To perform vital capacity test.

15. To evaluate reflex action of limbs, eyes.

16. To study clinical features, mode of transmission and prevention of communicable diseases.


1. S.R. Kale & R.R. Kale, Practical Human Anatomy & Physiology, Nirmal Prakashal, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

10


Branch: B. Pharmacy

Subject: Pharmaceutical Chemistry III (Organic-2) Lab. Code: 341229(41)




1. Identification of functional groups of organic compounds. 2. Identification of unknown sample of organic compounds. (eg: Citric acid, Tartaric acid, Oxalic acid,

Naphthol, Glucose, Sucrose, Starch) 3. Melting Point determination, boiling point determination, solubility studies, recrystallization, functional

group determination(carbonyls) 4. Preparation of respective compounds. 5. Prepare and submit Phthalimide from Phthalic anhydride. 6. Prepare and submit Iodoform from ethanol. 7. Prepare and submit Fluorescein from Phthalic anhydride

8. Prepare and submit Aspirin from Salicylic acid. 9. Prepare and submit Eosin from Fluorescein. 10. Prepare and submit Picric acid from phenol 11. Prepare and submit Benzamide from Benzoyl Chloride. 12. Prepare and submit Benzoic acid from Benzamide.


1. B.S. Furniss, A.J. Hannaford, P.W.G. Smith & A.R. Tatchell, Vogel‟s text Book of Practical Organic

Chemistry, Pearson Publication, New Delhi.

2. A.A. Siddiqui & Md. Ali, Practical Pharmaceutical Chemistry, C.B.S. Publication, New Delhi.

3. A.A. Siddiqui & Md. Ali, Experimental pharmaceutical Chemistry, C.B.S. Publication, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

11



Subject: English Communication Code: 341220(41)



List of Practical (A minimum of 10 tasks shall be performed)

1. Make a list of nonverbal communication

2. How body language is casually conditioned?

3. Take passages of descriptive, expressive and social functions and analyses them.

4. Expressive (exposing feelings) language in English and your mother-tongue

5. Make a list of sexist language (e.g. poetess, chairman)

6. Mentally retarded should be replaced by mentally challenged. Make a list of similar Expressions

7. Say formula expressions (Thank you, sorry, hello, that‟s right) with proper intonation

8. Make a list of words which should be avoided because they sound pompous. Which words would you

use instead of them?

9. How to express pleasure, regret, and approval?

10. Time and tense are not the same. Give some examples.

11. Take similar vowels and consonants and practice them in pairs of words.

12. Practice, stress and intonation in connected speech.

13. Conversation practice in familiar situations (Play the role of a tailor and a customer, for example)

14. Ask for specific information (can you tell me where the railway station is?)

15. Making a request (can I borrow your scooter, please?)

16. Asking for permission (Do you mind if I drive your car?)


1. Geoffrey Leach and Jan Svartvik, Longman, A Communicative Grammar of English, Pearson Education

Pvt. Ltd.

2. J.K. Chand and B.C. Das, A Millennium Guide to Writing & Speaking English, Friends‟ Publishers.

3. J.D.O‟ Connor, Better English Pronunciation, ELBS.

4. John Sealy, Oxford Guide to Writing and Speaking, OUP.

5. Mark MaCormack : “Communication”

6. John Metchell “ How to write reports”

7. Greenbaum, Greenbaum Sidney, A Student's Grammar of the English Language, Pearson Education

India, 2005

8. Douglas Biber, Susan Conrad, Geoffrey N. Leech, Longman Student Grammar of Spoken and Written

English: Workbook, Volume 1-4, Longman, 2002

9. Geoffrey N. Leech, Meaning And The English Verb, Pearson/Longman, 2004

10. Saraswati, English Language Teaching:Principles&Practice, Orient Blackswan, 2004

11. Percival Christopher Wren, H. Martin, High School English Grammar and Composition, S.Chand &

Company, 1995

www.Pharmainfo.Net

www.Pharmainfo.Net

12

12. Dr. B.B.Jain, Learn To Write Correct English (Eng.-Hindi), Upkar Prakashan, 2010

13. Kumkum Bhardwaj, Professional Communication, I. K. International Pvt Ltd, 2008

14. Jayanthi Dakshina Murthy, Correct Your Common Errors In English, Upkar Prakashan, 2010

15. Raymond Murphy, English Grammar In Use without Answers: A Reference and Practice Book for

Intermediate Students of English, Cambridge University Press, 2004

www.Pharmainfo.Net

www.Pharmainfo.Net

13



Subject: Field Work Code: 341228(41)



Visit and report on any one of the following:

1. Hospital pharmacy, medicinal plant garden, chemist shops of particular locality and community health centres.

2. Health camp organized by WHO, NGO‟s Government and private organization or by institute (Pulse-polio and vaccination).

3. Development and maintenance of medicinal plant garden in the institute campus.

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University B. Pharmacy Second Year,

THIRD SEMESTER, (New) from 2012 - 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks

Credit=L+[T+

P]/2 Theory

L T P ESE CT TA

1 341316(41) Pharmacy Pharmaceutics -IV (Physical Pharmacy- I) 4 1 - 70 20 10 100 5

2 341317(41) Pharmacy Pharmaceutical Analysis-I 4 1 - 70 20 10 100 5

3 341318(41) Pharmacy Computer Application 4 1 - 70 20 10 100 5

4 341319(41) Pharmacy Pharmacognosy- II 4 1 - 70 20 10 100 5

5 341331(41) Pharmacy Mathematics 4 1 - 70 20 10 100 5

6 341332(41) Pharmacy English Communication- II 4 1 - 70 20 10 100 5

7 341326(41) Pharmacy Pharmaceutics - IV (Physical Pharmacy- I) (Lab) - - 3 60 - 40 100 2

8 341327(41) Pharmacy Pharmaceutical Analysis- I (Lab) - - 3 60 - 40 100 2

9 341328(41) Pharmacy Computer Application - - 3 60 - 40 100 2

10 341329(41) Pharmacy Pharmacognosy- II (Lab) - - 3 60 - 40 100 2

TOTAL 24 6 12 660 120 220 1000 38



www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI

Semester: 3rd

Branch: B.Pharmacy

Subject: Pharmaceutics- IV (Physical Pharmacy- I) Code: 341316 (41)




Module: 1 (8 Hrs.)

1.1. Matter, Properties of Matter : States of matter, change in the state of matter, latent heat and vapour

pressure, sublimation, critical point, eutectic mixtures, gases, aerosols ,inhalers, relative humidity, liquid

complexes, liquid crystals, glassy state, solids crystalline, amorphous and polymorphism.

Module: 2 (8 Hrs.)

2.1. Thermodynamics: First, second and third laws, Zeroth law, absolute temperature scale, thermo

chemical equations, phase equilibria and phase rule.

2.2. Solutions: Ideal and real solutions, solution of gases in liquids, colligative properties, partition

coefficient, conductance and its measurement. Debye Huckel theory.

Module: 3 (8 Hrs.)

3.1. Viscosity and Rheology: Law of flow, kinematic viscosity, effect of temperature, Newtonian systems,

non-Newtonian systems, pseudoplastic, dilatant, plastic flow.Thixotropy, thixotropy in formulation,

determination of viscosity using capillary, falling ball and rotational viscometers.

Module: 4 (8 Hrs.)

4.1. Buffers: Buffer solution, buffer equations and buffer capacity, buffers in pharmaceutical systems,

buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.

4.2. Adsorption: Freundlich and Gibbs’ adsorption isotherms, Langmuir theory of adsorption, BET equation.

Module: 5 (8 Hrs.)

5.1. Surface and Interfacial Phenomenon : Surface tension and interfacial tensions, surface free energy,

measurement of surface tension and interfacial tension, spreading coefficient, adsorption at liquid

interfaces, surface active agents, HLB classification, solubilization, detergency, adsorption at solid

interfaces, solid-gas and solid-liquid interfaces, complex films, electrical properties.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd

Branch: B. Pharmacy

Subject: Pharmaceutical Analysis-I Code: 341317 (41)




Module: 1 (8 Hrs.) 1.1. Introduction: Significance of qualitative analysis in quality control, Different techniques of analysis,

Preliminaries and definitions, Significance of figures. Rules for retaining significant digits. Types of errors, minimization of error, selection of sample, precision and accuracy. Fundamentals of volumetric analysis, methods of expressing concentration, primary and secondary standards.

Module: 2 (8 Hrs.) 2.1. Acid Base Titration: Acid base concepts, role of solvents, Relative strength of acids and bases,

lonization, Law of mass action, Common ion effect, ionic product of water, pH, Hydrolysis of salts, Henderson-Hesselbalch equation, Buffers solutions, Neutralization curves, Acid-base indicators, Theory of indicators, Choice of indicators, Mixed indicators, Polyamine and amino acid systems. Amino acid titration, applications in assay, H3PO4, NaOH, CaCO3.

Module: 3 (8 Hrs.) 3.1. Precipitation Titrations: Precipitation reactions, solubility product, effect of acids, temperature and

solvent upon the solubility of a precipitate, Argentometric titration and titrations involving ammonium or potassium thiocyanate, mercuric nitrate orthophosphoric acid, sodium hydroxide, calcium carbonate and barium sulphate, Indicators, Gay-Lussac method; Mohr’s method, Volhard’s method and Fajan’s

method.

Module: 4 (8 Hrs.) 4.1. Non-aqueous titrations: Basic principles of Acidimetry and Alkalimetry, solvents involved, indicators.

Typical examples of Acidic and Basic drug molecules. 4.2. Complexometric titration: Types of complexometric titrations, Metal ion indicators, Complexometric

titrations involving EDTA. Typical examples of complexometric titration.

Module: 5 (8 Hrs.) 5.1. Gravimetric Analysis: Precipitation techniques, solubility products. The colloidal state, supersaturation,

co-precipitation, post precipitation, Digestion, washing of the precipitate, Filtration, Filter papers and crucibles, Ignition. Thermo gravimetric curves, specific examples like barium sulphate, aluminum as aluminum oxide, calcium as calcium oxalate and magnesium as magnesium pyrophosphate, organic precipitants.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd

Branch: B. Pharmacy

Subject: Computer Application Code: 341218 (41)




Module: 1 (8 Hrs.)

1.1. Introduction to computer, definition of computer, Block diagram of computer, history of computer, parts of computer (Key board, mouse, CPU, printer), memory of computers, operating systems.

Module: 2 (8Hrs.)

2.1 Classification of computer: Types of computers (mini, micro, mainframe, super computer, analog and digital computers). Hardware and software, calculator and computer.

Module: 3 (8 Hrs.)

3.1. MS-Word: MS-Word environment, working with word documents, formatting text, checking spellings and grammar, creating table, updating, deleting table and print documents.

Module: 4 (8 Hrs.)

4.1. MS-EXCEL: working with MS-EXCEL, insert and delete cell, workbook, adding spreadsheet, some basic formulas, print spreadsheet.

4.2. MS-POWERPOINT: Power point environment, working with power point, create new slide, formatting slide, animation in slide and slide show.

Module: 5 (8 Hrs.)

5.1. Introduction to multimedia text, voice, graphics, animation, image, introduction to internet, search engine, downloading data, www, web site and webpage.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd Branch: B. Pharmacy

Subject: Pharmacognosy-II Code: 341319 (41)



Module: 1 (6 Hrs.)

1.1. Cultivation, Collection, Processing and storage of crude drugs:

Factors influencing cultivation of medicinal plants, Type of Soils & fertilizers of common use.

1.1.1. Pest and Pest Management, natural pest control agents.

1.1.2. Plant hormones and their applications.

1.1.3. Polyploidy, Mutation and hybridization with reference to medicinal plants.

1.1.4. Poly Houses/ Green Houses for cultivation.

Module: 2 (4 Hrs.)

2.1. Resins: Study of Drugs Containing Resins and Resin Combination like Podophyllum, Cannabis, Capsicum, Myrrh, Asafoetida, Balsam of Tolu, Balsam of Peru, Benzoin, Turmeric, Ginger.

2.2. Tannins: Study of tannins and tannin containing drugs like Black catechu, Gall and Arjuna.

Module: 3 (8 Hrs.)

1.1. Volatile Oils:

3.1.1. General methods of extraction of volatile oils from plants, Study of biological source, chemical constituents, chemical tests and uses of volatile oils of Mentha, Lemon peel, Orange peel, Sandal wood, Citronella, Dill, Nutmeg, Chenopodium, Valerian, Musk, Palmarosa, Gaultheria.

3.1.2. Detailed Pharmacognosy of Clove, Coriander, Lemon grass, Cardamom, Cinnamon and Eucalyptus.

Module: 4 (10 Hrs.)

4.1. Phytochemical Screening: An introduction to active constituents of drugs, their isolation, classification and properties with Qualitative chemical tests of the followings –

Alkaloids, Saponins, Cardenolides and bufadienolides, flavonoids and Leucoanthocyanidine, cyanogenetic glycosides.

Module: 5 (12 Hrs.)

5.1. Study of the biological sources, chemical constituents, substitutes, adulterants, uses, macroscopic and microscopic features and specific chemical tests of following groups of drugs containing glycosides :

5.1.1. Saponins: Ginseng, Dioscorea, Sarsaparilla.

5.1.2. Cardioactive sterols: Digitalis, Squill, Thevetia.

5.1.3. Anthraquinone cathartics: Aloe, Rhubarb, Cascara.

5.1.4. Others: Psoralea, Ammi Majus, Ammi Visnaga, Gentian, Chirata, Quassia.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd

Branch: B. Pharmacy

Subject: Mathematics Code: 341331 (41)




Module: 1 (8 Hrs.)

1.1. Matrix, determinants, definition of differential coefficient, differentiation of standard function.

Module: 2 (8Hrs.)

Basic concept of definite and indefinite integral, application of integration in pharmacy, logarithms.

Module: 3 (8 Hrs.)

3.1. Basic concepts of data: graphical representation of data, diagrammatic representation of data, measures of central tendencies, measures of dispersion.

Module: 4 (8 Hrs.)

4.1. Correlation, regression, skewness, standard deviation, standard errors of means.

Module: 5 (8 Hrs.)

5.1. Introduction to probability, some basic probability, probability distribution, normal distribution, poisson distribution, t-test, f-test.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd

Branch: B. Pharmacy

Subject: English Communication – II Code: 341332 (41)




Module: 1 (8 Hrs.)

1.1. Writing: Paragraph writing ( topic sentence, cohesion and coherence, sentence linkers)

Module: 2 (8 Hrs.)

2.1. Preparation of a business report: Writing a business proposal – format, length, structure.

Module: 3 (8 Hrs.)

3.1. Preparing notes: writing business letters and E-Mail messages Module: 4 (8 Hrs.)

4.1. Documentation: References, notes and bibliographies, Writing curriculum vitae (both chronological and functional) along with an application for a job.

4.2. Public relation: concept and relevance public relation in a business organization-handing the media.

Module: 5 (8 Hrs.)

5.1. Meeting and presentation: Organizing a meeting, preparing an agenda, chairing a meeting drafting resolutions, writing minutes; Making an oral presentation; Facing an interview.


1. Bovee et al, Business Communications Today Pearson Education. 2. J.V. Vilanilam, More effective Communication, Sage Publication. 3. J .K. Chand & B.C. Das, A Millennium Guide to Writing & Speaking English, Friends’ Publishers.

4. Sushil Bahl, Business Communication Today, Sage Publications. 5. John Sealy, Oxford Guide to Writing & Speaking English, OUP. 6. Pati and Khuntia, Communicative English & Business Communication, Alok Pub.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3 rd

Branch: B. Pharmacy

Subject: Pharmaceutics-IV (Physical Pharmacy-I) Lab. Code: 341326 (41)



List of Practicals (A minimum of 10 experiments shall be conducted)

1. Study of different states of matter of same/ different materials 2. To prepare eutectic mixtures 3. To study colligative properties of liquids Elevation of boiling point Depression of freezing point

4. To determine the surface tension of given sample by drop count/ weight method. 5. To determine partition coefficients of any two suitable drug materials 6. To determine the HLB value of the given surfactant. 7. To determine surface tension by stalagmometer & by capillary rise method 8. To determine the CMC of given the surfactant by surface tension method. 9. To determine interfacial tension between 2 liquids using Ostwald’s viscometer. 10. To determine the percent composition of an unknown solution of glycerin in water using Ostwald’s

viscometer. 11. To determine viscosity of liquid by falling ball 12. To prepare acetate buffer and compare theoretical pH value with the experimental value. 13. To prepare a given percentage of solution by allegation method 14. To study adsorption phenomenon by activated charcoal 15. To observe the effect of dielectric constant of solvent on drug solubility

16. Determination of latent heat, vapor pressure, critical point of various liquids.


1. A. Martin, Physical Pharmacy, Lippincott Williams & Wilkins, London.

2. S.J. Carter, Tutorial Pharmacy, Copper & Gunn, CBS Publishers, New Delhi.

3. E.A. Rawlins, Bentley, Bailliere Tindall, Textbook of Pharmaceutics, London.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd Branch: B. Pharmacy

Subject: Pharmaceutical Analysis-I Lab. Code: 341327 (41)




1. Standardization of analytical weights and calibration of volumetric apparatus. 2. Preparation and standardization of sodium carbonate, potassium hydrogen phthalate, Sodium

bicarbonate, oxalic acid solution. 3. Assay of boric acid, ammonium carbonate. 4. Preparation and standardization of silver nitrate and ammonium thiocyanate solution. 5. Titration according to Mohr’s and Volhard’s methods. 6. Preparation and standardization of perchloric acid and sodium methoxide and assay of one official

drug under each type. 7. Preparation and standardization of EDTA solution and assay of calcium gluconate, magnesium

sulphate. 8. Assay of calcium by gravimetric analysis.

Text Books / Reference Books (Latest Edition): 2. Garratt, The Quantitative Analysis of Drugs, CBS Publishers & Distributors. 3. H.H. Willard, Instrumental Methods of Analysis, CBS Publishers, Delhi. 4. Vogel, Text book of Quantitative Chemical Analysis, (Person Education, Singapore).

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 3rd

Branch: B. Pharmacy

Subject: Computer Application Lab Code: 341328 (41)




1. Practical based on working with Windows 7 AND Windows xp environment e.g. File Management, Copying, Burning CD/DVD, understanding various formats of Operating system.

2. Practical based on MS Office(Word, Excel, Power point) .Integration of all three office tools to make an document including picture manager.

3. Safe Internet Browsing, E-Mail and basics of website development as based on free hosting sites. 4. Understanding Virus attack, basics and measures to avoid virus attack, hacking and file corruption.


1. V. Rajaraman, Fundamental of Computers, B.P.B. Publications. 2. P. K. Sinha, Fundamental of Computers. 3. Suresh Basandra, Computer Today. 4. Steve Sagman, MS- Office 2000 (For Windows) 5. Tennenbum, Computer Networks, Tata Mac Grow Hill Publication.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: 3rd

Branch: B. Pharmacy

Subject: Pharmacognosy-II Lab. Code: 341329 (41)




1. Perform macroscopic examination (Morphology and Organoleptic) of at least fifteen crude drugs mentioned in theory.

2. Perform microscopic studies of seven-selected crude drugs and their powders mentioned under the category of volatile oils and glycosides in theory and their chemical tests,

3. Perform General chemical tests for alkaloids, glycosides, steroids, phenols, flavonoids, resins and tannins.

4. Perform identification test of some resin containing drugs at least three drugs (Capsicum, Myrrh, Balsam of Tolu, Benzoin, Asafoetida, Turmeric, Ginger).

5. Perform procedure for extraction of volatile oils from at least two drugs (Mentha, Lemon peel, Orange peel, Dill, Lemon grass, Eucalyptus).

6. Perform chemical tests to identify phytoconstituents present in unknown drug sample.

7. Perform field experiment to demonstrate the effect of auxins and gibberlins on potted plants.

8. Perform experiment to demonstrate the effect of at least one physical and one chemical mutating agent on plant cells.


1. C. K. Kokate, A.P. Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune.

2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier.

3. T.E. Wallis, Text Book of Pharmacognosy, CBS Publishers & Distributors, New Delhi, Darya Ganj.

4. Text Book of Pharmacognosy, V.E. Tyler, L.R. Brady & J.E. Robbers, Len & Febiger, Philadelphia.

5. Essential of Pharmacognosy, S.H.Ansari, Birla Publication, Shahdara, New Delhi.

6. Analytical Microscopy, T. E. Wallis, J & A Churchill Limited, London.

7. K.R. Brain and T.D. Turner “The Practical Evaluation of Phyto Pharmaceutical”, Wright, Scientechnica- Bristol.

8. P, J. Schewer, Marine Natural products, Academic press, London.

9. Mohammed Ali, Pharmacognosy and Phytochemistry,

www.Pharmainfo.Net

www.Pharmainfo.Net


B. Pharmacy Second Year,

FORTH SEMESTER, (New) from 2012 – 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks

Credit=L+[T+P]/2 Theory

L T P ESE CT TA

1 341416(41) Pharmacy Pharmaceutics -V (Physical Pharmacy -II) 4 1 - 70 20 10 100 5

2 341417(41) Pharmacy Pharmaceutics -VI (Pharmaceutical Engineering- I ) 4 1 - 70 20 10 100 5

3 341418(41) Pharmacy Pharmaceutical Chemistry-IV (Organic chemistry-3) 4 1 - 70 20 10 100 5

4 341419(41) Pharmacy Pharmaceutical Biochemistry 4 1 - 70 20 10 100 5

5 341410(41) Pharmacy Pharmaceutical Microbiology 4 1 - 70 20 10 100 5

6 341426(41) Pharmacy Pharmaceutics -V (Physical Pharmacy -II) Lab - - 3 60 - 40 100 2

7 341427(41) Pharmacy Pharmaceutics -VI (Pharmaceutical Engineering-I) Lab

- - 3 60 - 40 100 2

8 341428(41) Pharmacy Pharmaceutical Chemistry- IV (Organic chemistry -3) Lab - - 3 60 - 40 100 2

9 341429(41) Pharmacy Pharmaceutical Biochemistry -Lab - - 3 60 - 40 100 2

10 341420(41) Pharmacy Pharmaceutical Micobiology - Lab - - 3 60 - 40 100 2

TOTAL 20 5 15 650 100 250 1000 35



www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th

Branch: B. Pharmacy

Subject: Pharmaceutics -V (Physical Pharmacy -II) Code: 341416 (41)




Module: 1 (8 Hrs.)

1.1. Micromeretics and Powder Rheology : Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle size, volume, shape, surface area, specific surface, derived properties of powders, porosity, packing arrangement, densities, bulkiness and flow properties.

Module: 2 (8 Hrs.)

2.1. Dispersion Systems: Colloidal dispersions, types, properties of colloids, protective colloids, applications of colloids in pharmacy; Suspensions: Interfacial properties of suspended particles, wetting of particles, controlled flocculation, flocculation in structured vehicles, rheological considerations, Emulsions: theories of emulsification, physical stability and rheological considerations.

Module: 3 (8 Hrs.)

3.1. Kinetics and Drug Stability: General considerations and concepts, half-life determination, Influence of temperature, light, solvent, catalytic species, accelerated stability study, determination of expiry date.

Module: 4 (8 Hrs.)

4.1. Solubility and related phenomenon: Solubility expression, Determination of solubility, Solubility of gases in liquids, Solubility of liquids in liquids, Solubility of solids in liquids.

4.2. Phase rule and phase diagram

Module: 5 (8 Hrs.)

5.1. Complexation: Classification of complexes, methods of preparation, analysis and applications.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4 th

Branch: B. Pharmacy

Subject: Pharmaceutics -VI (Pharmaceutical Engineering- I ) Code: 341417 (41)




Module: 1 (8 Hrs.)

1.1. Unit Operation: Unit operations and processes, Material and energy balances, Dimensionless equations; formulas and groups.

Module: 2 (8Hrs.) 1.1. Corrosion and its Prevention: General considerations, Types of Corrosion, Methods of reducing

Corrosion, Simple mathematical problems. 1.2. Fluid Flow: Fluid static, Manometers, Types of flow, Reynold’s Number and its significance, Concept of

boundary layers, Bernoulli’s theorem and its applications, Measurement of flow of fluids, Valves.

Module: 3 (8 Hrs.)

3.1. Material Handling Systems:

3.1.1. Liquid handling: Different types of pumps. 3.1.2. Solid handling: Conveyors. 3.2. Heat Transfer: Heat transfer mechanisms, Heat transfer by conduction, Fourier’s law, Natural and

forced convection, Surface and overall heat transfer coefficients, Heat transfer by radiation, Heaters and heat exchangers.

Module: 4 (8 Hrs.)

4.1. Humidity, Air-Conditioning and Refrigeration: Basic concepts and definitions of various terms. Psychrometric charts, Wet bulb theory, Measurement of humidity. Application of humidity measurement, air-conditioning and refrigeration in Pharmacy.

4.2. Automated Process Control Systems: Process variables, Temperature, Pressure, Flow, Level and Vacuum and their measurements. Elements of computer aided manufacturing (CAM).

Module: 5 (8 Hrs.)

5.1 Materials of Pharmaceutical Plant Construction: Factors affecting the material selection for pharmaceutical plants, Physical; Chemical; Mechanical properties and use of the important materials of construction with special reference to Ferrous metals, Copper, Aluminium, Nickel, Glass, Plastics and their alloys, Heat and Corrosion resistant alloys.

5.2 Pilot Plant Scale up Techniques: Concepts of pilot plant scale up techniques in pharmaceutical industries.

5.3 Industrial Hazards and Safety Measures: Mechanical, Chemical, Electrical, Fire and Dust Hazards, Safety requirements, Legal requirements, Industrial dermatitis.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th

Branch: B. Pharmacy

Subject: Pharmaceutical Chemistry-IV (Organic Chemistry-3) Code: 341418 (41)



Minimum number of class of tests to be conducted: 2

Module: 1 (8 Hrs.)

1.1 Esters: Nomenclature, preparations with special emphasis on synthesis of Malonic and acetoacetic esters and their synthetic applications.

1.2 Amines: Nomenclature, General methods of preparation, Physical and Chemical properties, Basicity.

Module: 2 (8 Hrs.) 2.1. Benzene and its homologues: Structure of benzene, Resonance, Aromatic character, Huckel Rule.

General methods of preparation, Physical properties, Electrophilic substitution reactions, Friedel crafts reaction, Catalytic hydrogenation.

2.2. Cycloalkanes: Nomenclature, General methods of preparation, Chemical reactions, Stability (Bayer strain theory), Conformational analysis of cyclohexane.

2.3. Nucleophilic aromatic substitution reactions, Electrophilic aromatic substitution reactions, Catalytic hydrogenation

Module: 3 (8 Hrs.) 3.1. Aniline: General methods of preparation, characteristic reactions. 3.2. Phenols: General methods of preparation, Acidity, Characteristic reactions. 3.3. Aromatic carboxylic groups

Module: 4 (8 Hrs.)

4.1. Selected reactions and mechanism of synthetic importance: Mannich reaction, Beckmann reaction, Fitting reaction, Di alder reaction, Birch Reduction.

4.2. Organic reagents used in drug synthesis

Module: 5 (8 Hrs.) 5.1. Heterocyclic Compounds: Nomenclature, structure and reactions of Imidazole, Indole, Pyrrole, Furan,

Pyrimidine, Quinoline and Isoquinoline.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th

Branch: B.Pharmacy

Subject: Pharmaceutical Biochemistry Code: 341419 (41)




Module: 1 (8 Hrs.)

1.1. Introduction: Biochemical organization of the cell and transport processes across cell membrane. Outlines of biochemistry of cell division and metastasis. The concept of free energy, determination of change in free energy from equilibrium constant and reduction potential, bioenergetics, production of ATP and its biological significance.

Module: 2 (8 Hrs.)

2.1. Enzymes: Nomenclature, factors affecting enzyme action, enzyme kinetics and its mechanism of action, mechanism of inhibition, enzymes and isoenzymes in clinical diagnosis.

2.2. Co-enzymes: Vitamins as co-enzymes and their significance, metals as co-enzymes and their significance.

Module: 3 (8 Hrs.)

3.1. Carbohydrate Metabolism: Glycolysis and fermentation and their regulation, Gluconeogenesis, Glycogenolysis, Glycogenesis, and Pentose phosphate Pathway.

3.2. The Citric Acid Cycle: Significance, reactions and energetics of the cycle, Amphibolic role of the cycle and Anaplerosis.

Module: 4 (8 Hrs.)

4.1. Lipid Metabolism: Oxidation of fatty acids; β-oxidation & energetics, α-oxidation, ω- oxidation, Biosynthesis of ketone bodies and their utilization, Biosynthesis of saturated and unsaturated fatty acids, control of lipid metabolism, Essential fatty acids & Biosynthesis of eicosanoids (prostaglandins, thromoboxanes and leukotrienes), phospholipids and sphingolipids.

Module: 5 (8 Hrs.)

5.1. Biosynthesis of nucleic Acids: Brief introduction to genetic organisation, organisation of mammalian genome, alteration and rearrangement of genetic material, biosynthesis of DNA and its replication, mutation, physical and chemical mutagenesis/carcinogenesis, DNA repair mechanism, biosynthesis of RNA.

5.2. Genetic code and Protein synthesis: Genetic code, Components of protein synthesis and inhibition of protein synthesis. Brief account of genetic engineering and polymerase chain reactions. Regulation of gene expression.

5.3. Principles of biological oxidation and detoxification mechanisms.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th

Branch: B. Pharmacy

Subject: Pharmaceutical Microbiology Code: 341410 (41)




Module: 1 (8 Hrs.)

1.1. Introduction to the scope of microbiology. 1.2. Structure of bacterial cell. 1.3. Classification of microbes and their taxonomy. Actinomycetes, bacteria, rickettsiae, spirochetes and

viruses.

Module: 2 (8 Hrs.)

2.1. Identification of Microbes: Stains and types of staining techniques, electron microscopy. 2.2. Nutrition, cultivation, isolation of bacteria, actinomycetes, fungi, viruses.

Module: 3 (8 Hrs.)

3.1. Microbial genetics and variation. 3.2. Control of microbes by physical and chemical methods. 3.2.1. Disinfection, factors influencing disinfectants, dynamics of disinfection, disinfectants and antiseptics

and their evaluation. 3.2.2. Sterilization, different methods, validation of sterilization methods & equipments.

Module: 4 (8 Hrs.) 4.1. Sterility testing of all pharmaceutical products. 4.2. Immunity, primary and secondary, defensive mechanisms of body, microbial resistance, interferon.

Module: 5 (8 Hrs.)

5.1. Microbial assays of antibiotics, vitamins and amino acids. 5.2. Definition and uses of BOD and COD. 5.3. Industrial sewage treatment

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: 4

th

Branch: B. Pharmacy

Subject: Pharmaceutics-V (Physical Pharmacy-II) Lab. Code: 341426 (41)




1. To determine the particle size and particle size distribution in the given sample of powder by optical microscopy method.

2. To determine particle size and size distribution of the given sample of granule by sieving method. 3. To determine the following derived properties of the given powdered sample

(a) Flow property (b) Bulk density (c) Granule density (d) True density (e) Porosity (f) Carr’s Index (g)

Hausner’s ratio 4. To determine the true density of given sand sample (non porous). 5. To determine angle of repose/ flow rate of given powder sample. 6. To determine the porosity of given sample of powder. 7. To prepare an emulsion & determine its type of various method. 8. To evaluate the physical stability of an emulsion. 9. To prepare flocculated and deflocculated suspensions 10. To determine the optimum concentration of tragacanth required for maximum physical stability of

calcium carbonate suspension. 11. To determine the most suitable suspending agent for maximum physical stability of calcium carbonate

suspension. 12. To determine the reaction rate constant and half life of an ester in 0.5 N HCl at room temperature. 13. To determine the order of reaction by half life method. 14. To perform aspirin degradation by colorimetry by complexometry method 15. To determine upper convolute temperature for phenol-water system. 16. Ternary phase diagram.


1. Martin, Physical Pharmacy and Pharmaceutical Sciences, Williams & Wilkins, London. 2. E.A. Rawlins, Bentley, Textbook of Pharmaceutics, Bailliere Tindall, London. 3. S.J. Carter, Tutorial Pharmacy, Copper and Gunn, CBS Publishers, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4

th

Branch: B. Pharmacy

Subject: Pharmaceutics-VI (Pharmaceutical Engineering-I) Lab Code: 3414127 (41)




1. To determine radiation constant of Iron cylinder and to interpret the influence of temperature on radiation constant.

2. To determine radiation constant of Copper cylinder and to interpret the influence of temperature on radiation constant.

3. To determine radiation constant of Brass cylinder. 4. To determine overall heat transfer coefficient of water. 5. To determine the Reynolds number and frictional factor by calculating frictional loses in pipes in which fluids

are flowing. 6. To determine the Reynolds number by calculating velocity of fluids and area of pipes in which fluids are

flowing. 7. To determine the humidity of air by using dew point method. 8. To determine relative humidity by using psychometric chart. 9. To determine rate of corrosion of different metals in a given environment (acid medium, basic medium,

neutral) of a metal. 10. To determine rate of corrosion of different metals in a given environment. 11. To study of different types of conveyors. 12. To study of different types of valves. 13. To study of various types of pumps. 14. To draw alphabets in capital letters in given engineering drawing sheet. 15. To draw four objects in different angles on engineering drawing sheet 16. Study of various elements of computer aided manufacturing.


1. W.L Badger and J.T Banchero, Introduction to Chemical Engineering McGraw Hill Intematonal Book Co., London.

2. K. Sambamurty, Pharmaceutical Engineering, New Age International, New Delhi. 3. Introduction to Chemical Engineering, Tata Mcgraw Hill, New Delhi. 4. S.J. Carter, Tutorial Pharmacy, Cooper & Gunn, CBS Publishers, New Delhi. 5. C.V.S. Subrahmanyam et al, Pharmaceutical Engineering Principles and Practices. 6. Pharmaceutics-The Science of Dosage Form Design, Churchill Livingstone, London.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4

th

Branch: B. Pharmacy

Subject: Pharmaceutical Chemistry-IV (Organic chemistry -3) Lab Code: 341428 (41)




1. Preparation of organic compounds and their derivatives, crystallization and determination of their melting point or boiling point.

2. Analysis of organic compounds containing different functional groups. 3. Identification of mono-functional organic compounds by a study of their physical properties, detection

of characteristic functional group reactions and preparations of the rational derivative. (Acid, Phenol, Aldehyde, ketones, amides, esters, hydrocarbons and carbohydrates.

4. Esterification of alcohols. 5. Monographs of selected official drugs including identification tests and tests for purity.

(eg: Aspirin, Paracetamol, Ascorbic acid)


1. R.T. Morrison & R. N. Boyd, Organic Chemistry, Pearson Education, Latest Edition. 2. B.S. Bahl & Arun Bahl, Advanced Organic Chemistry, S. Chand Publisher, New Delhi. 3. O.P. Agarwal, Organic Chemistry – Reactions & Reagents, Krishna Prakashan, Meerut. 4. I.L. Finar, Organic Chemistry, Vol. I & Vol. II, Pearson Education. 5. Bentley & Driver, A Text Book of Pharmaceutical Chemistry, Oxford University Press, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th

Branch: B. Pharmacy

Subject: Pharmaceutical Biochemistry Lab Code: 341429 (41)




1. Preparation of standard buffers (citrate, phosphate and carbonate) and measurement of pH. 2. Colorimetric estimation of blood glucose. 3. Estimation of cholesterol, creatinine, urea and uric acid in biological fluids. 4. Qualitative test for normal and abnormal constituents of urine. 5. Estimation of reducing sugars in urine. 6. Estimation of bilirubin contents of the blood. 7. Enzymatic hydrolysis of glycogen by alpha and beta amylases. 8. Effect of temperature on the activity of alpha amylases. 9. Estimation of Blood Cholesterol 10. Estimation of SGOT, SGPT by UV Spectrophotometer. 11. Estimation of serum alkaline phosphate and acid phosphatase levels. 12. Estimation of serum sodium, potassium and calcium levels.


1. Harper’s Illustrated Biochemistry, R. K. Murray & D. K. Granner, P. Mayes, Mc Grawhill Publisher. 2. A.C. Deb, Fundamentals of Biochemistry, New Central Book Agency, Calcutta. 3. A.V.S.S. Rama Rao, Text Book of Biochemistry, UBS Publishers & Distributors, New Delhi. 4. Satyanarayana, U.Chakrapani, Text Book of Biochemistry, Books & Allied (Pvt.) Ltd., Vijayawada. 5. Lehringer Principles of Biochemistry, David L. Nelson, Michael M. Cox, W.H. Freemann & Company

New York. 6. West & Todd, Text Book of Biochemistry, (Oxford & IBH Pub., Co., New Delhi)

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: 4

th

Branch: B. Pharmacy

Subject: Pharmaceutical Microbiology Lab. Code: 341420 (41)




1. Identification of microorganism by different microscopical and staining methods. 2. Prepare & sterilize Nutrient Agar. 3. Prepare & sterilize Thioglycolate media. 4. Microbial assays of antibiotics. 5. Microbial assays of vitamins. 6. Study of the lactose fermenting bacteria from milk sample using differential plating. 7. Testing the sterility of pharmaceutical products.(Creams & ointments) 8. Sterility test for aqueous solution & suspension. 9. Sterility test for water for injection. 10. Study the effect of pH of the culture media on the growth of microbes. 11. Study the effects of osmotic pressure on growth of microbes.

Text Books / Reference Books (Latest Edition): 1. Pelczar & Kreig, Microbiology, Pub Tata McGraw – Hill, New Delhi. 2. Anantanarayana & Panicker, Text Book of Microbiology, Orient Longman Pvt. Ltd., Chennai. 3. Bernard R. Glick, Jack J. Pastemak, Molecular Biotechnology – Principal & application of

recombinant DNA, Deptt. Of Biology, University of Waterloo, Waterloo, Ontario, Canada. ASM Press Washington DC.

4. S.P. Vyas & V.K. Dixit, Pharmaceutical Biotechnology, CBS Publishers & Distributors. 5. L. M. Prescott, G. P. Jarely, D.A. Klein, Microbiology, Wm C Brown Publishers, Oxford. 6. Prescott and Dunn, Industrial Microbiology, McGraw Hill Book Company Inc. 7. N.K. Jain, Pharmaceutical Microbiology, Vallabh Prakashan, Delhi. 8. A.H. Patel, Industrial Microbiology, MAC Millan, India Ltd. 9. L.E. Casida, Industrial Microbiology, JR, New AGC International (P) Ltd. Publishers

www.Pharmainfo.Net

www.Pharmainfo.Net


B. Pharmacy Third Year,

FIFTH SEMESTER, (New) from 2012 – 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks

Credit=L+ [T+P]/2 Theory

L T P ESE CT TA

1 341516(41) Pharmacy Pharmaceutics -VII (Pharmaceutical Engineering- II) 4 1 - 70 20 10 100 5

2 341517(41) Pharmacy Medicinal Chemistry-I 4 1 - 70 20 10 100 5

3 341518(41) Pharmacy Pharmacognosy-III 4 1 - 70 20 10 100 5

4 341519(41) Pharmacy Pharmacology-I 4 1 - 70 20 10 100 5

5 341510(41) Pharmacy Pharmaceutics VIII (Cosmetic technology) 4 1 - 70 20 10 100 5

6 341526(41) Pharmacy Pharmaceutics -VII (Pharmaceutical Engineering II) (LAB) - - 3 60 - 40 100 2

7 341527(41) Pharmacy Medicinal Chemistry-I (LAB) - - 3 60 - 40 100 2

8 341528(41) Pharmacy Pharmacognosy- III (LAB) - - 3 60 - 40 100 2

9 341529(41) Pharmacy Pharmacology-I (LAB) - - 3 60 - 40 100 2

10 341520(41) Pharmacy Pharmaceutics VIII (Cosmetic technology) (LAB) - - 3 60 - 40 100 2

TOTAL 20 5 15 650 100 250 1000 35



www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5th Branch: B. Pharmacy

Subject: Pharmaceutics -VII (Pharmaceutical Engineering- II) Code: 341516(41)



Module: 1 (8 Hrs.) 1.1. Size Reduction and Size Separation: Definition objectives and significance of size reduction, Factors

affecting size reduction, Standard of powders, Sieves and their usage in grading of powders, Laws governing energy and power requirements of a mill, Classification of size reduction machines, Study of various types of mill including ball mill, hammer mill, fluid energy mill.

1.2. Evaporation: Basic concepts, Factors affecting evaporation, Types of evaporators, Study of short tube evaporators, Forced circulation evaporators and Film evaporators, Single and multiple effect evaporation, Evaporation under reduced pressure, Evaporation capacity, Heat and material balance, Scale formation, Foam and entrainment.

Module: 2 (8 Hrs.) 2.1. Drying: Introduction, Theory of drying Rate of drying curves, Classification of dryers, Study of dryers

used in pharmaceutical industries, Special drying methods. 2.2. Extraction: Principles of solid-liquid and liquid- liquid extraction, Theories of extraction of drugs,

Diffusion battery, Continuous counter-current extraction system.

Module: 3 (8 Hrs.) 3.1. Mixing: Theory of mixing, Solid -solid, solid-liquid and liquid- liquid mixers used in\ pharmaceutical

industries 3.2. Centrifugation: Principles of centrifugation, Industrial filters and centrifugation sedimenters.

Module: 4 (8Hrs.)

4.1. Crystallization: Importance of crystal purity, size, shape, geometry, habit, forms and types. Solubility curves and calculation of yields, Mier’s supersaturation theory and its limitations, Nucleation and crystal

growth, Classification of crystallizers, Principles underlying the design and operation of Tank, Swenson-walker, Krystal and Vacuum crystallizer. Crystallizer employed for producing large crystals, Caking of crystals and its prevention.

4.2. Filtration: Theory of filtration, Factors affecting filtration, Filter media, Filter aids, Classification of filters, Industrial filters including Filter press, Rotary filter, Membrane filter.

Module: 5 (8 Hrs.) 5.1. Distillation: General theory applied to binary mixtures, Boiling point and equilibrium diagrams, Raoult’s

Law and Henry’s Law, Constant boiling mixtures. Simple, steam and Equilibrium distillations. Rectification, Constructions of rectifying columns. Analysis of rectifying column: McCabe Thiele method and Lewis Sorel method for calculation of number of theoretical plates, Azeotropic and extractive distillations.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Medicinal Chemistry-I Code: 341517(41)



Module: 1 (8 Hrs.)

1.1. Basic Principles of Medical Chemistry: Physico-chemical aspects (Optical, geometric and bioisosterism) of drug molecules and biological action; Drug receptor interaction including transduction mechanisms.

1.2. Brief concept on QSAR: Derivation of Hansch analysis and discussion on different parameters like electronic parameters, steric factor, and partition coefficient.

Module: 2 (8 Hrs.)

Classification, mode of action, uses and structure activity relationship of the following classes of

drugs. Synthesis of those compounds only exemplified against each class.

2.1. Drugs acting on autonomic nervous system:

2.1.1. Cholinergics and Anticholinergic: Acetylcholine, Carbachol, Bethanechol, methacholine, Neostigmine, Edrophonium, Demecarium, Atropine.

2.1.2. Adrenergic drugs and adrenergic blocking agents: Adrenaline, Ephedrine, Salbutamol, Phenylephrine, Naphazoline,

2.1.3. Antispasmodic and anti-ulcer drugs: Homatropine, Cyclopentolate, Diclomine, Tropicamide. Module: 3 (8 Hrs.)

3.1. Drugs acting on autonomic nervous system:

3.1.1. Neuromuscular blocking agents: Gallamine, succinylcholine 3.1.2. Local Anaesthetics: Benzocaine, Procaine, Lignocaine

3.2. Drugs affecting uterine motility: Oxytocins (including oxytocin, ergot alkaloids and prostaglandins) their Occurrence, Chemical nature, Medicinal applications.

Module: 4 (8 Hrs.)

4.1. Autacoids:

4.1.1. Antithistamines: Diphenhydramine, Mepyramine, Chlorpheniramine, Promethazine, Chlorcyclizine, Cimetidine, Ranitidine.

4.1.2. Eicosanoids: Occurrences, Chemical nature, Medicinal applications 4.1.3. Analgesic–antipyretics, anti-inflammatory (non-steroidal) agents: Aspirin, 4.1.4. Paracetamol, Ibuprofen, Phenylbutazone, Naproxen, Diclofenac sodium, mefenamic acid. Module: 5 (8 Hrs.)

5.1 Structure of the following drugs: Paralidoxime, Donepezil, Ipratropium bromide, Propantheline, Terbutaline, Dobutamine, Propanolol, Doxazocin, Labetolol, Tripelennamine, Dimenhydrinate, Doxylamine, Triprolidin, Cetrizine, Cyproheptadine, Astemizole, Oxyphenylbutazone, Piroxicam, Ketoprofen, Probenecid, Allopurinol, Tubocurarine, Physostigmine, Nimesulide, Celecoxib.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5 th Branch: B. Pharmacy

Subject: Pharmacognosy-III (Natural Products) Code: 341518 (41)




Module: 1 (14 Hrs.)

1.1. Chemical and spectral approaches to simple molecules of natural origin as exemplified by Reserpine, Morphine, Quinine and Menthol.

1.2. Biosynthesis: Introduction to biogenesis

1.1.1. Employment of Radio-tracer techniques in Biogenetic studies.

1.1.2. A brief account of primary and secondary metabolite’s production from carbon

metabolism in plants.

1.1.3. Study of Calvin cycle, TCA cycle, Shikimic acid pathway

1.1.4. Embden-Maerhoef pathway, acetate hypothesis, isoprenoid pathway.

1.1.5. Biosynthesis of carbohydrates, lipids and volatile oils.

Module: 2 (06 Hrs.)

2.1. Extraction, Isolation and Chemistry of

2.1.1. Glycosides - Digitoxin, Diosgenin & Sarasapogenin

2.1.2. Lignans- Secoisolariciresinol diglycoside

2.1.3. Quassinoids- Bruceantin

2.1.4. Flavonoids- Rutin, Quercetin

Module: 3 (08 Hrs.)

3.1. Extraction, Isolation and Chemistry of Alkaloids

3.1.1. Atropine & related compounds

3.1.2. Quinine, reserpine, morphine, papaverine, ephedrine, ergot

3.1.3. Vinca Alkaloids.

3.2. Extraction, Isolation and Chemistry of Xanthine bases: Caffeine, theophylline and

theobromine.

Module: 4 (06 Hrs.)

4.1. Extraction, Isolation and Chemistry of Terpenoids:

Camphor, Menthol, Citral, β- Carotene, α -Tocopherol, α-Pinene.

Module: 5 (06 Hrs.)

5.1. Study of Natural Pesticides and Insecticides: Tobacco, Pyrethrum, Cevadilla, Neem, Ryania.

5.2. Introduction to herbicides, fungicides, fumigants and rodenticides

5.3. Study of Toxic Drugs: Allergens, hallucinogens, narcotics, mycotoxins, toxic mushrooms and Indian toxic plants.

5.4. A brief introduction to natural plant bitters and sweeteners.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmacology-I Code: 341519 (41)




Module: 1 General Pharmacology (8 Hrs.) 1.1 Introduction to Pharmacology, Sources of drugs, routes of administration, mechanism of action,

combined effect of drugs, Factors modifying drug action, Tolerance and dependence 1.2 Pharmacokinetics: Absorption, Distribution, Metabolism and Excretion of drugs 1.3 Pathophysiology of common diseases; (Asthma, diabetes, gout, ulcerative colitis, acute and chronic

renal failure, hypertension, angina, congestive heart failure, hepatic disorders, tuberculosis, urinary

tract infections). 1.4 Basic Principles of Cell Injury and Adaptations: Causes of Cellular injury, pathogenesis, morphology of cell injury, adaptations and cell death. Basic Mechanisms involved in the process of inflammation and repair: Module: 2 Pharmacology of drugs acting on Peripheral Nervous System (8 Hrs.) 2.1. Neurohumoral transmission (autonomic and somatic) 2.2. Cholinergic drugs, Cholinergic blockers 2.3. Adrenergic drugs, Adrenergic blockers 2.4. Ganglionic stimulants and blocking agents skeletal muscle relaxants

Module: 3 Pharmacology of drugs acting on Central Nervous System (8 Hrs.) 3.1 Neurohumoral transmission in the Central Nervous System 3.2 Local anaesthetic agents, general anaesthetics 3.3 Alcohol and treatment of alcoholism 3.4 Sedatives, hypnotics, Anti-epileptic drugs Module: 4 Psychopharmacological agents (8 Hrs.) 4.1. Antipsychotics (Neuroleptic drugs), Antidepressants, Anti-anxiety drugs 4.2. Anti-parkinsonism drugs, Central Nervous System stimulants 4.3. Drug addiction and Drug abuse

Module: 5 Drugs Used In Management of Pain (8 Hrs.) 5.1. Narcotic analgesics and antagonists 5.2. Analgesics, Antipyretics, Anti-inflammatory and Treatment of arthritis

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics VIII (Cosmetic technology) Code: 341510 (41)




Formulation, packaging and evaluation of the following categories of cosmetics:

Module: 1 (8 Hrs.)

1. Face Preparations: Face powder, Compact powder, Talcum powder, Face packs and Masks.

2. Skin Preparations: Skin creams, Anti-wrinkle preparations, Barrier materials, Protective creams and gels,

Vanishing creams, Cold creams, Cleanising creams Skin moisturisers, Sunscreen, burn preparations.

Module: 2 (8 Hrs.)

3. Shaving preparations: Lather shaving stick, Lather shaving cream, Shaving foams, Shaving gels, Pre- and

After shave lotions.

4. Shampoo and Bath preparations: Clear liquid shampoo, Aerosol shampoo, dry shampoo, Acid-balanced

shampoo, Egg shampoo, Bath oils, Foam baths.

Module: 3 (8 Hrs.)

5. Hair Preparations: Hair tonics, Hair conditioners, Hair lotions, Hair sprays, Hair dressings, Hair setting

lotions and creams, Hair dyes, Bleaches, Hair waiving, Hair straightners and Hair strengthners.

6. Dentrifice: Tooth powders, Tooth pastes, Solid dentrifice, Tooth brush and Denture cleansers.

Module: 4 (8 Hrs.)

7. Foot Preparations: Foot powders, Foot sprays, Foot creams, Corn preparations and Athelete’s foot

preparation.

8. Manicure Preparations: Nail polish, Nail lacquer and Nail bleach.

Module: 5 (8 Hrs.)

9. Herbal Cosmetics: Cosmetics containing Aloe, Babul, Brahmi, Chandan, Cucumber, Haldi, Jatamansi,

Khus, Mehandi, Neem, Reetha, Shikakai, Tulsi, Arnica, Amla, Bhringraj and Volatile oils

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5

th

Branch: B. Pharmacy

Subject: Pharmaceutics-VII (Pharmaceutical Engineering-II) Lab. Code: 341526(41)




1. To compare the efficiency of size reduction of a mixer and a ball mill. 2. To determine the size distribution of particles present in the given sample (powder or granules). 3. To determine rate of evaporation influenced by different factors (surface area, viscosity,

concentration). 4. To perform the evaporation under reduced pressure by using Rota- evaporator. 5. To separate the pure liquid from & given impure liquid mixture-(simple distillation). 6. To find out the efficiency of steam distillation process for distillation of high boiling solvents from &

non-volatile substance (liquid-mixture) [steam distillation]. 7. To identify the azeotropic mixture with the different Techniques of distillation of distillation method. 8. To construct Boiling point Diagram of miscible liquids. 9. To dry a given wet solid and to construct drying curve. 10. To determine rate of drying influenced by different factors (various parameters). 11. To compare the extraction efficiencies of single and multiple stage extractions. 12. To observe the effects of various factors on the nature of crystal growth of a super saturated solution

by different method. 13. To construct the solubility curve of a given drug (NaCl) at different temperature and to plot a

solubility curve. 14. To study the effect of filter-aid on the rate of filtration and to determine the optimum concentration of

filter-aid. 15. To study the factors effecting the rate of filtration of solutions. 16. To verify the stokes law for a given sphere (solid materials) in a given liquid. 17. To estimate the sedimentation time for the formulation having different concentrations of suspending

agents by using centrifugation. Text Books / Reference Books (Latest Edition):

1. W.L Badger and J.T Banchero, Introduction to Chemical Engineering McGraw Hill Intematonal Book Co.,

London. 2. Warren L. McCabe, Julian C. Smith, Peter Harriott, Unit Operations of Chemical Engineering, McGraw

Hill Intematonal Edition Book Co.,London

3. K. Sambamurty, Pharmaceutical Engineering, New Age International, New Delhi. 4. Introduction to Chemical Engineering, Tata Mcgraw Hill, New Delhi. 5. S.J. Carter, Tutorial Pharmacy, Cooper & Gunn, CBS Publishers, New Delhi. 6. C.V.S. Subrahmanyam et al, Pharmaceutical Engineering Principles and Practices.

7. Pharmaceutics-The Science of Dosage Form Design, Churchill Livingstone, London.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: 5th

Branch: B. Pharmacy

Subject: Medicinal Chemistry-I) Lab. Code: 341527(41)




1. Synthesis of selected chemical compounds of pharmaceutical importance. (Aspirin, benzamide, Benzoic acid, Phenytoin, Paracetamol, Phenacetin, Fluorescein, Eosin, Benzil, Benzilic acid, Trinitrophenol, Phenylbenzoate, Phthalamide)

2. Monographs of selected official drugs including identification tests and tests for purity.


1. Wilson & Grisvold, Text Book of Organic Medicinal & Pharmaceutical Chemistry, Lippincott Williams & Wilkins. 2. William Foye, Principles of Medicinal Chemistry, Lippincott Williams & Wilkins. 3. S. N. Pandeya, A Text Book of Medicinal Chemistry, SG Publisher, Varanshi. 4. Ashutosh Kar, Medicinal Chemistry, New Age International Publishers, New Delhi. 5. Bentley & Driver, Text Book of Pharmaceutical Chemistry, Oxford University Press, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5th

Branch: B. Pharmacy

Subject: Pharmacognosy-III (Natural Products) Lab. Code: 341528 (41)




1. Estimation of following organic groups: hydroxyl (alcoholic and phenolic), amino, carboxylic groups and acetyl group.

2. Preparation of different Alkaloid testing reagents like Dragendroff, Mayer’s, Wagner’s, etc. and testing

some alkaloids and Plant extracts using these reagents.

3. Identification of Alkaloids by specific colour tests.

4. Tests for steroids, steroidal glycosides and cardiac glycosides. Liberman-Burchard test, Salkowski reaction, Kedde reaction, etc.

5. Tests for flavanoids and their glycosides. Shinoda Test (Mg /HCl test), Fecl3 test.

6. Test for terpenoids

7. TLC Examination of Alkaloids, Steroids, Steroidal Glycosides and Cardiac Glycosides.

8. Isolation of caffeine from tea leaves.

9. Isolation of digitoxin from digitalis leaves.

10. Isolation of rutin from any two sources (orange, grapefruit, lemon, lime).

11. Isolation of menthol from mentha.

12. Isolation of atropine from datura leaves.

13. Isolation of curcumin from Curcuma longa.


1. C. K. Kokate, A.P.Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune. 2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier. 3. T.E. Wallis, Text Book of Pharmacognosy, CBS Publishers & Distributors, New Delhi. 4. V.E. Tyler, L.R. Brady & J.E. Robbers, Text Book of Pharmacognosy, Lea & Febiger, Philadelphia,

Recent Ed. 5. S.H. Ansari, Essential of Pharmacognosy, Birla Publication, Shahdara, New Delhi. 6. T. E. Wallis, Analytical Microscopy, J&A Churchill Limited, London. 7. K.R. Brain and T.D.Turner. “The Practical Evaluation of Phyto Pharmaceutical”, Wright, Scientechnica-

Bristol. 8. P, J. Schewer, Marine Natural products, Academic press, London. 9. Brain, K.R., & Turner T.D, The Practical evaluation of phytopharmaceutical, Wright, Bristol. 10. Sim, Medicinal Plant Alkaloids & Glycosides. 11. C. K. Kokate, Practical Pharmacognosy, Vallabh Prakashan, New Delhi. 12. E. Stahl, Thin layer chromatography, A Laboratory Hand Book , Springer Verlag, Berlin. 13. J.B. Harborne, Phytochemical Methods, Chapman & Hall, International Ed, London. 14. I.L. Finar, Organic chemistry, Vol. I & II ELBS, London. 15. O.P. Agarwal, Chemistry of Organic Natural Product, Vol. I & II Goel Pub. House, Meerut. 16. J. S. Qadry, B.S. Shah Pharmaconosy, Vallabh Prakashan. 17. J. B. Pridham & T. Swain, Biosynthetic pathway Higher plants, Academic Press, New York. 18. D. J. Abraham, Medicinal Chemistry & Drug Discibery, Berger’s, John Wiley & Sons, New Jersey.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5th

Branch: B. Pharmacy

Subject: Pharmacology-I Lab. Code: 341529 (41)



List of Practicals

1. To study the student organ bath 2. To prepare and submit 50 ml of physiological salt solution (Frog Ringer). 3. To draw and study the animal house equipments 4. To study the techniques of holding the animals. 5. To study the different routes of administration of drugs in mice. 6. To study the effect of Acetylcholine on rectus abdominus muscle of frog with the help of software. 7. To study the local anaesthetics on rabbit cornea with the help of software. 8. To record the concentration response curve of Histamine on guinea Pig’s ileum with the help of

software.

Text Books / Reference Books (Latest Edition): 1. K.D. Tripathi, Essentials of Medical Pharmacology, JAYPEE. 2. Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman, L E

Limbird, P B Molinoss, R W Ruddon and A G Gil, Pergamon Press." 3. Satoshkar and Bhandarkar, Pharmacology & Parmacotherapeutics, Popular Publication. 4. M.P. Rang, M.M .Dale, l. M. Riter, Pharmacology, Churchill Livingstone. 5. J. Crossland and J.H. Thomson., Essentials of Pharmacology, Harper and Row Publishers NY 6. Craig C R and Stitzel R R, Modem Pharmacology, Little Brown and Company. 7. S.R Kale, R.R Kale and S.A Hasan, Practical Pharmacology and Toxicology. Nirali Prakashan. 8. S.K. Kulkarni., Handbook of Experimental Pharmacology, Vallabh Prakashan Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 5th

Branch: B. Pharmacy

Subject: Pharmaceutics VIII (Cosmetic technology) Lab. Code: 341520 (41)



Experiments to be performed:

Exp.1 - To study the structure & functions of skin & hair.

Exp.2 - Prepare & submit talcum powder.

Exp.3 - Prepare & submit face powder.

Exp.4 - Prepare & submit vanishing cream.

Exp.5 - Prepare & submit moisturizing cream.

Exp.6 - Prepare & submit bleaching cream.

Exp.7 - Prepare & submit anti sun burn cream.

Exp.8 - Prepare & submit lather shaving cream.

Exp.9 - Prepare & submit after shave lotion.

Exp.10 - Prepare & submit hair shampoo.

Exp.11 - Prepare & submit hair creams.

Exp.12 - Prepare & submit tooth powder & tooth paste.

Exp.13 - Prepare & submit athelete’s foot prepration.

Exp.14 - Prepare & submit nail polish.

Exp.15 - Prepare & submit herbal cosmetics containing Aloe, Haldi, Mehndi & Amla.

Reference / Recommend Books:

1. Harry’s cosmeticology

2. Sagarin & Balsam, M.S. conmetic Science and Technology, Vol. 1-3, John Wiley & Sons, NY, USA

3. Mac Chesney, J.C. Packaging of Cosmetic and Toiletries, Newsness Butterworth, London.

4. Jellinek, J.S., Formulation and Functions of Cosmetics, John willey & sons, New York.

5. Thomssen, SG., Modern Cosmetics, Universal Publishing corporation, Bombay.

www.Pharmainfo.Net

www.Pharmainfo.Net


B. Pharmacy Third Year,

SIXTH SEMESTER, (New) from 2012 – 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks


L T P ESE CT TA

1 341616(41) Pharmacy Pharmaceutics -IX (Pharmaceutical Technology- I) 4 1 - 70 20 10 100 5

2 341617(41) Pharmacy Medicinal Chemistry -II 4 1 - 70 20 10 100 5

3 341618(41) Pharmacy Pharmacology - II 4 1 - 70 20 10 100 5

4 341619(41) Pharmacy Pharmaceutical Analysis II 4 1 - 70 20 10 100 5

5 341610(41) Pharmacy Pharmaceutical Biotechnology 4 1 - 70 20 10 100 5

6 341625(41) Pharmacy Pharmaceutics -IX (Pharmaceutical Technology- I) (LAB) - - 3 60 - 40 100 2

7 341626(41) Pharmacy Medicinal Chemistry- II (LAB) - - 3 60 - 40 100 2

8 341627(41) Pharmacy Pharmacology II (LAB) - - 3 60 - 40 100 2

9 341628(41) Pharmacy Pharmaceutical Analysis II (LAB) - - 3 60 - 40 100 2

10 341629(41) Pharmacy Pharmaceutical Biotechnology (LAB) - - 3 60 - 40 100 2

TOTAL 20 5 15 650 100 250 1000 35



www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics -IX (Pharmaceutical Technology- I) Code: 341616 (41)




Module: 1 (8 Hrs.)

1.1. Preformulation Studies: Preformulation studies of API: BCS classification, Study of physical properties of drug like physical form, particle size, shape, density, wetting, dielectric constant. Solubility, dissolution and organoleptic properties and their effect on formulation, stability and bioavailability.

Module: 2 (8 Hrs.)

2.1. Semisolid Dosage Forms: Definitions, types, mechanisms of drug penetration, factors influencing penetration, semisolid bases and their selection. General formulation of semisolids, clear gels manufacturing procedure, evaluation and packaging.

2.2. Suppositories: Ideal requirements, bases, manufacturing procedure, packaging and evaluation.

Module: 3 (8 Hrs.)

3.1. Pharmaceutical Aerosols: Definition, propellants, general formulation, manufacturing and packaging methods, pharmaceutical applications.

Module: 4 (8 Hrs.)

4.1. Blood Products and Plasma Substitutes: Collection, processing and storage of whole human blood, concentrated human RBCs, dried human plasma, human fibrinogen, human thrombin, human normal immunoglobulin, human fibrin, foam plasma substitutes, -ideal requirements, PVP, dextran etc. for control of blood pressure as per I.P.

Module: 5 (8 Hrs.)

5.1. Liquid Dosages Forms: Introduction, types of additives used in formulations, Vehicles, stabilizers, preservatives, suspending agents, emulsifying agents, solubilizer, colors, flavours and others, manufacturing packaging and evaluation of clear liquids, suspensions and emulsions official in pharmacopoeia.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Medicinal Chemistry II Code: 341617 (41)






Module: 1 (8 Hrs.)

1.1. Drugs acting on the Central Nervous System:

1.1.1. General Anaesthetics: Anaesthetic ether, Halothane, Thiopental Sodium. 1.1.2. Hypnotics and Sedatives: Hexobarbitone, Phenobarbitone, Cyclobarbitone, Glutethimide, Diazepam 1.1.3. Opioid analgesics: Pethidine, Methadone.

Module: 2 (8 Hrs.)

2.1. Drugs acting on the Central Nervous System:

2.1.1. Anticonvulsants: Phenytoin, Ethosuximide, Primidone, Carbamazepine 2.1.2. Antiparkinsonism drugs: Levodopa, Amantidine, Biperiden, Procyclidine 2.1.3. CNS stimulants: Caffeine, Nikethemide, Amphetamine, Pentylene tetrazole. Module: 3 (8 Hrs.)

3.1. Sulphonamides

3.2. Anticoagulant and Antiplatelet Drugs. 3.3. Thyroid and antithyroid Drugs.

3.4. Vitamins: Vitamin A, Thiamine, Riboflavin, Folic Acid, Niacin, Panthotenic Acid, Pyridoxine, Cyanocobalamine, Vitamin C, Vitamin D, Vitamin E, Vitamin K.

Module: 4 (8 Hrs.)

4.1. Psychopharmacological agents (neuroleptics, antidepressants, anxiolytics):

Chlorpromazine, Haloperidol, Impiramine, Phenelzine, Chlordiazepoxide,Alprazolam. 4.2. Combinatorial Chemistry- Introduction, combinatorial approaches, applications, methodology,

introduction to High Throughputs Screening (HTS).

Module: 5 (8 Hrs.)

5.1. Structure of Some Drugs: Nitrazepam, Meprobromate, Phenosuximide, Valproic Acid, Ipronizid, Flupherazine, Methaqualone, Paraldehyde, Chloralhydrate, Allobarbitone, Methohexital sodium, Benztropine, Doxapram, Ethamivam , Fluoxentine, Trazodom, Bupropion, Cycrimine, Ethopropazine, Alpidem, Hydroxyzine.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmacology - II Code: 341618 (41)



Minimum number of class of tests to be conducted:

Module: 1 Pharmacology of drugs acting on Cardiovascular System (8 Hrs.)

1.1. Digitalis and cardiac glycosides, treatment of CHF 1.2. Antihypertensive drugs 1.3. Antianginal and vasodilator drugs 1.4. Antiarrhythmic drugs 1.5. Antihyperlipidemic drugs, 1.6. Diuretics

Module: 2 Principles of Toxicology (8 Hrs.)

2.1. Definition of poisons

2.2. Adverse drug reactions

2.3. General principles of treatment of poisoning with particular reference of barbiturates, opioids, organophosphorous, paracetamol and atropine poisoning.

Module: 3 Drugs Acting on the Haemopoetic System (8 Hrs.)

3.1. Haematinics

3.2. Anticoagulants, Fibrinolytic and anti-platelet drugs

3.3. Vitamin K and haemostatic agents

Module: 4 Autacoids (8 Hrs.)

4.1. Histamine, 5-HT and their antagonists

4.2. Prostaglandins, thromoboxanes and leukotrienes.

Module: 5 Drugs Acting on the Respiratory System (8 Hrs.)

5.1. Anti-asthmatic drugs including bronchodilators

5.2. Anti-tussives and expectorants

5.3. Respiratory stimulants

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutical Analysis II Code: 341619 (41)




Theoretical considerations and application in drug analysis and quality control of the following

analytical techniques:

Module: 1 (8 Hrs.)

1.1. Oxidation Reduction Titrations : Concepts of oxidation and reduction, Redox reactions, strengths and equivalent weights of oxidizing and reducing agents, Theory of redox titrations, Redox indicators, cell representations, Measurement of electrode potential, Oxidation-reduction curves, Iodimetry and Iodometry, Titrations involving ceric sulphate, potassium iodate, potassium bromate, potassium permanganate, Titanous chloride and sodium 2, 6-dichlorophenol indophenol.

Module: 2 (8 Hrs.)

2.1. Miscellaneous Methods of Analysis: Diazotisation titrations, Kjeldahl method of nitrogen estimation, Karl-Fischer titration, Oxygen flask combustion gasometry.

2.2. Potentiometry and pH Meter.

Module: 3 (8 Hrs.)

3.1. Conductometry 3.2. Polarography 3.3. Amperometry

Module: 4 (8 Hrs.)

4.1. Radioimmunoassays 4.2. ELISA tests 4.3. Electrophoresis, Immunoelectrophoresis.

Module: 5 (8 Hrs.)

5.1. Thermoanalytical methods: Thermogravimetry, Differential Thermal Analysis, Differential Scanning Calorimetry, Thermometric titration.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutical Biotechnology Code: 341610 (41)




Module: 1 (8 Hrs.)

1.1. Historical Development

1.2. Immunology and Immunological Preparations: Principles, Antigens and antibodies, Antigen-

antibody reactions and their applications, Immune system. Cellular humoral immunity, Immunological

tolerance, Hypersensitivity, Immunological and diagnostic preparations: Methods of their preparation,

standardization and storage.

Module: 2 (8 Hrs.)

2.1. Enzyme Immobilization: Techniques of Immobilization of enzymes, kinetics and factors affecting

enzymes kinetics, Enzymes electrodes, Enzymes based sensors, Study of enzymes produced by

biotechnology, Immobilization of bacteria and plant cells, Applications of Immobilization.

Module: 3 (8 Hrs.)

3.1. Genetic Recombination: Transformation, Conjugation, Transduction, Protoplast fusion, Gene

mutation, Gene cloning and their applications, Monoclonal antibodies and hybridoma technology,

Recombinant DNA technology: Concepts, Methodology and Pharmaceutical applications. Study of

drugs such as Activase, Humulin, Humatrope, HB etc, Drug delivery systems in Gene therapy,

transgenic plants-pest and disease resistance.

3.2. Proteomics, genomics (genome and human genome project), DNA Fingerprinting, concept of

bioinformatics.

3.3. Plant tissue culture techniques.

Module: 4 (8 Hrs.)

4.1. Microbiological Transformation: Introduction, Types of reactions mediated by microorganisms. Design

of biotransformation processes, Selection of organisms, Biotransformation processes and its

improvements with special reference to steroids.

Module: 5 (8 Hrs.)

5.1. Industrial Biotechnology: Historical development, Fermenter and its design, Control of different parameters in fermentation process. Isolation of mutants, factors influencing rate of mutation. Design of fermentation process, production of Penicillin, streptomycins, tetracyclines and vitamin B12.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 6th Branch: Pharmacy

Subject: Pharmaceutics-IX (Pharma technology-I) Lab. Code: 341625 (41)

Total Practical Periods: 36 Total Marks in End Semester Examination: 60


1. To perform solubility studies on drugs in different solvents. 2. To determine particle size of drug powder by optical microscopy. 3. To perform stability of active pharmaceutical ingredient. 4. To prepare, evaluate and submit Paracetamol suspension 50 ml. 5. To prepare, evaluate and submit Paracetamol syrup. 6. To prepare, evaluate and submit Iodine ointment. 7. To prepare and evaluate Ibuprofen Ointment 8. To prepare, evaluate and submit Salicylic acid ointment 10gm IP. 9. To prepare, evaluate and submit emulsifying ointment-IP.

10. To prepare and evaluate Diclofenac Gel. 11. To prepare, evaluate and submit suppositories.

12. To prepare and evaluate Diclofenac Sodium Suppositories. 13. To prepare and evaluate Benzyl benzoate application. 14. To study micromeritic properties of excipients like microcrystalline cellulose, dibasic calcium

phosphate, lactose etc. 15. To study the rheology of semisolids like ointments creams, gels etc. 16. To study the flow rate/ rheological properties with different size of particles / granules.


1. Lachmann L, Lieberman HA and Kanig J L, The Theory and Practice of Industrial Pharmacy, Lea & Febiger, Philadelphia.

2. E.A. Rawlins Bentley, Textbook of Pharmaceutics, Tindall, London. 3. Ansel, Allen & Popovich, Pharmaceutical Dosage Forms & Drug Delivery Systems, Lippincott Williams &

Wilkins, London. 4. Lippincott Williams & Wilkins Science & Practice of Pharmacy, Remington, London. 5. Sagarin & Balsam M S Cosmetic Science and Technology, Vol 1-3, 2nd ed John Wiley & Sons, NY. 6. S. Saraf & S. Saraf, Cosmetics: A Practical Manual, Pharma Book Syndicate.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 6th

Branch: B. Pharmacy

Subject: Medicinal Chemistry-II Lab. Code: 341626 (41)




1. Synthesis of selected drugs of Pharmaceutical importance. 2. Monographs of selected official drugs including identification tests and tests for purity. ( Ascorbic acid, Prochlorperazine, Riboflavin, Chloramphenicol, Isoniazid, Chlorpropamide, Caffeine, Omeprazole, Ondansetron)

TEXT BOOKS/ REFERENCE BOOKS (Latest Edition):

1. Wilson & Gisvold, Text Book of Organic Medicinal & Pharmaceutical Chemistry, Lippincott Williams & Wilkins, Latest Edition.

2. William Foye, Principles of Medicinal Chemistry, Lippincott Williams & Wilkins, Latest Edition. 3. S.N. Pandeya, A Text Book of Medicinal Chemistry, SG Publisher, Varanshi, Latest Edition. 4. Ashutosh Kar, Medicinal Chemistry, New Age International Publishers, New Delhi, Latest Edition. 5. Bentley & Driver, Text Book of Pharmaceutical Chemistry, Oxford University Press, New Delhi, Latest

Edition. 6. G Ozin, A. Arsenault, Nanochemistry: A chemical approach to nanomaterials, RSC Publishing.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: 6th

Branch: B. Pharmacy

Subject: Pharmacology-II Lab. Code: 341627 (41)




1. To record the dose response curve (DRC) of acetylcholine cockerel ileum. 2. To record the DRC of histamine on isolated loop of guinea pig ileum. 3. To calculate the pA2, value of mepyramine or chlorpheniramine using histamine as agonist on isolated

loop of guinea pig ileum. 4. To estimate the strength of the test sample of agonist/drug (e.g. Acetylcholine, Histamine) using a

suitable isolated muscle preparation employing matching bioassay, Bracketing assay. 5. Study of agonists, antagonists and ions on frog heart (simulated exp). 6. Effect of different drugs on rabbit eye (simulated exp). 7. Effect of drugs on neuromuscular junction (simulated ex). 8. Study of neurotransmission with the help of visual aids.

Text Books / Reference Books (Latest Edition): 1. K.D. Tripathi, Essentials of Medical Pharmacology, JAYPEE. 2. Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman, L E

Limbird, P B Molinoss, R W Ruddon and A G Gil, Pergamon Press." 3. Satoshkar & Bhandarkar, Pharmacology & Parmacotherapeutics, Popular Publication. 4. Rang MP, Dale MM, Riter lM., Pharmacology, Churchill Livingstone. 5. Crossland J and Thomson J H., Essentials of Pharmacology, Harper and Row Publishers NY 6. Craig C R and Stitzel R R, Modem Pharmacology, Little Brown and Company, 1994. 7. S.R Kale, R.R Kale and S.A Hasan, Practical Pharmacology and Toxicology. Nirali Prakashan, Latest Edition. 8. S.K. Kulkarni., Handbook of Experimental Pharmacology, Vallabh Prakashan Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 6th

Branch: B. Pharmacy

Subject: Pharmaceutical Analysis-II Lab. Code: 341628 (41)




1. Exercise involving diazotization, Kjeldahl, Karl-Fischer, shall be covered. 2. Exercises based on acid base titration in aqueous and non-aqueous media, oxidation reduction titrations

using potentiometric technique. 3. Determination of acid-base dissociation constants and plotting of titration curves using pH meter. 4. Exercises involving conductometric titrations. 5. Preparation and standardization of some redox titrants e.g. potassium permanganate, potassium

dichromate, iodine, sodium thiosulphate. 6. Some exercises related to determination of oxidizing and reducing agents in the sample shall be

covered. 7. Exercises involving potassium iodate, potassium bromate, iodine solution, sodium 2, 6-

ichlorophenolindophenol, and ceric ammonium sulphate. Text Books/ Reference Books (Latest Edition):

1. Vogel, Text Book of Quantitative Chemical Analysis, Pearson Education. 2. B.K. Sharma, Instrumental Methods of Chemical Analysis, Goel Publishing House. 3. Bentley & Driver, Text Book of Pharmaceutical Chemistry, Oxford Medical Publication. 4. Beckett & Stenlake, Practical Pharmaceutical Analysis, CBS Publishers &Distributors. 5. Pharmacopoeia of India Vol. I & II., Ministry of Health, Govt. of India, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 6th

Branch: B. Pharmacy

Subject: Pharmaceutical Biotechnology Lab. Code: 341629 (41)




1. To prepare & evaluate enzyme immobilized calcium alginate beads. 2. To extract tyrosinase from potato and study the substrate specificity on different substrate. 3. To determine the enzyme kinetics of pepsin. 4. Enzyme immobilization with gelatin gel solution. 5. To isolate DNA from onion. 6. To treat yogurt fermentation with lactobacillus bacteria. 7. To isolate RNA from yeast cell. 8. A, B, O Blood group typing of own blood IgM mediated agglutination reaction. 9. To estimate total protein content in alginate beads by biurate reagents. 10. To isolate enzyme urease & determine its practical yields. 11. Batch submerged Fermentation of broken’s yeast. 12. To isolate lecithin from egg yolk. 13. To isolate glutein from wheat flour. 14. To perform separation of amino acids by using TLC. 15. To prepare alcohol by using fermentation process.

Text Books / Reference Books (Latest Edition): 1. K. Kielslich, Ed Biotechnology Vol 6 a, Verleg Chemie, Switzerland. 2. R.S. Setty, G.R. Veena, Biotechnology I, New Age, New Delhi. 3. Setty Sreekrishna, Biotechnology II, New Age, New Delhi. 4. S. Mahesh, Biotechnology III, New Age, New Delhi. 5. Mahesh Vedamurthy, Biotechnology IV, New Age, New Delhi. 6. M.K. Mahesh, Biotechnology V, New Age, New Delhi. 7. K. Trehan, Biotechnology, New Age, New Delhi. 8. S.J. Carter, Cooper and Gunn’s Tutorial Pharmacy, CBS Publishers, Delhi. 9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, ELBS Balliere tindall. 10. W.B. Hugo, and A.D. Russell, Pharmaceutical microbiology, Blackwell Scientific Pubication, Oxford. 11. A. Wiserman, Handbook of enzyme biotechnology, Ellis Harwood Ltd., Chichester 12. L.E. Cassida Industrial Microbiology, Wiley, Eastern Limited, New Delhi. 13. M. Weir Donald, John Stewart, Immunology, Churchill Livingstone, London.

www.Pharmainfo.Net

www.Pharmainfo.Net


B. Pharmacy Forth Year,

SEVENTH SEMESTER, (New) from 2012 – 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks


L T P ESE CT TA

1 341716(41) Pharmacy Pharmaceutics –X (Pharmaceutical Technology -II) 4 1 - 70 20 10 100 5

2 341717(41) Pharmacy Pharmaceutics-XI (Biopharmaceutics & Pharmacokinetics ) 4 1 - 70 20 10 100 5

3 341718(41) Pharmacy Medicinal Chemistry- III 4 1 - 70 20 10 100 5

4 341719(41) Pharmacy Pharmacology- III 4 1 - 70 20 10 100 5

5 341710(41) Pharmacy Pharmacognosy- IV 4 1 - 70 20 10 100 5

6 341725(41) Pharmacy Pharmaceutics –X (Pharmaceutical Technology -II ) Lab - - 3 60 - 40 100 2

7 341726(41) Pharmacy Pharmaceutics- XI (Biopharmaceutics & Pharmacokinetics ) Lab - - 3 60 - 40 100 2

8 341727(41) Pharmacy Pharmacology –III (Lab) - - 3 60 - 40 100 2

9 341728(41) Pharmacy Pharmacognosy- IV (Lab) - - 3 60 - 40 100 2

10 341729(41) Pharmacy Industrial Training and report writing - - - - - 100 100 2

TOTAL 20 5 12 590 100 310 1000 35



www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics -X (Pharmaceutical Technology -II) Code: 341716(41)




Module: 1 (8 Hrs.)

1.1 Capsules: Advantages and disadvantages of capsule dosage form, material for production of hard gelatin capsules, size of capsules, method of capsule filling, soft gelatin, capsule shell and capsule content, importance of base absorption and minimum/gm factors in soft capsules, quality control, stability testing (ICH Guidelines) and storage of capsule dosage forms.

Module: 2 (8 Hrs.)

2.1 Tablets:

2.1.1 Formulation of different types of tablets, granulation, technology on large-scale by various techniques, physics of tablets making, different types of tablet compression machinery and the equipments employed, evaluation of tablets.

2.1.2 Coating of Tablets: Types of coating, film forming materials, formulation of coating solution, equipments for coating, coating process, evaluation of coated tablets.

Module: 3 (8 Hrs.)

3.1. Parenteral Products:

3.1.1. Preformulation factors, routes of administration, water for injection, pyrogenicity, non-aqueous vehicles, isotonicity and methods of its adjustment.

3.1.2. Formulation details, containers and closures and selection. 3.1.3. Prefilling treatment, washing of containers and closures, preparation of solution and suspensions,

filling and closing of ampoules, vials, infusion fluids, lyophillization & preparation of sterile powders, equipment for large scale manufacture and evaluation of parenteral products.

3.1.4. Aseptic Techniques-source of contamination and methods of prevention, Design of aseptic area, Laminar flow bench services and maintenance.

3.1.5. Sterility testing of pharmaceuticals.

Module: 4 (8 Hrs.)

4.1. Ophthalmic Preparations: Requirements, formulation, methods of preparation, containers, evaluation. 4.2. Stability Studies: Stability kinetics, In process quality control and quality assurance, ICH Guidelines for

stability testing of active pharmaceutical ingredients and finished pharmaceutical products Module: 5 (8 Hrs.)

5.1 Packaging of Pharmaceutical Products: Packaging components, types, specifications and methods of evaluation, stability aspects of packaging. Packaging equipments, factors influencing choice of containers, legal and other.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics-XI (Biopharmaceutics & Pharmacokinetics) Code: 341717(41)



Module: 1 (8 Hrs.)

1.1. Introduction to Biopharmaceutics and Pharmacokinetics and their role in formulation development and clinical setting.

1.2. Biopharmaceutics: 1.2.1. Passage of drugs across biological barrier (passive diffusion, active transport, facilitated diffusion and

pinocytosis). 1.2.2. Factors influencing absorption - Physicochemical, physiological and pharmaceutical. 1.2.3. Drug distribution in the body, plasma protein binding. 1.2.4. Different types and mechanism of drug metabolism in the body. 1.2.5. Drug excretion through other routes than gastrointestinal and urinary: Excretion of drugs in saliva,

tears, sweat, milk, semen.

Module: 2 (8 Hrs.)

2.1. Pharmacokinetics:

2.1.1. Significance of plasma drug concentration measurement. 2.1.2. Compartment model: Definition and Scope.

Pharmacokinetics of drug absorption: Zero order and first order absorption rate constant using Wagner - Nelson and Loo- Reigelman method.

2.1.3. Volume of distribution and distribution coefficient. 2.1.4. Compartment kinetics: One compartment and two compartment models. Determination of

pharmacokinetic parameters from plasma and urine data after drug administration by intravascular and oral route.

Module: 3 (8 Hrs.)

3.1. Curve fitting (method of Residuals), regression procedures. 3.2. Clearance concept, Mechanism of renal clearance, clearance ratio, determination of renal clearance. 3.3. Extraction ratio, hepatic clearance, biliary excretion, Extrahepatic circulation. 3.4. Non-linear pharmacokinetics with special reference to one compartment model after drug administration, 3.5. Michaeles Menten Equation, detection of non-linearity (Saturation mechanism).

Module: 4 (8 Hrs.)

4.1. Clinical Pharmacokinetics: Definition and scope, Dosage adjustment in patients with and without renal and hepatic failure, Design of single dose bio-equivalence study and relevant statistics, Pharmacokinetic drug interactions and their significance in combination therapy.

Module: 5 (8 Hrs.)

5.1. Bioavailability and bioequivalence : 5.1.1. Measures of bioavailability, Cmax, t max, and Area under the Curve (AUC). 5.1.2. Design of single dose bioequivalence study and relevant statistics. 5.1.3. Review of regulatory requirements for conduction of bioequivalent studies.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Medicinal Chemistry- III Code: 341718(41)






Module: 1 (8 Hrs.)

1.1. Steroids and Related Drugs: General study on Steroidal nomenclature and stereochemistry, Androgens and anabolic agents, Estrogens and progestational agents,: synthesis of Progesterone from diosgenin, Diethyl stilbesterol, Synthesis of Testosterone from Cholesterol, General study of structural formula and therapeutic uses of steroidal antinflammatory agents.

1.2. Antiviral Drugs: Zidovudine, Didanosine, Vidarabine.

Module: 2 (8 Hrs.)

2.1. Cardiovascular, Hypertensive Drugs: Disopyramide phosphate, Clonidine, Methyldopa, Procainamide, Hydralazine, Nifedipine, Isosorbide dinitrate, Prazocin, clofibrate.

2.2. Insulin and Oral Hypoglycemic Agents: Insulin, Glibenclamide, Metformin.

Module: 3 (8 Hrs.)

3.1. Antibiotics (Used in Chemotherapy): Beta-lactam Antibiotics: Penicillin, Cephalosporin, Aminoglycoside antibiotics, Macrolide antibiotics, Tetracyclines, Chloramphenicol.

Module: 4 (8 Hrs.)

4.1. Antineoplastic Agents: Mechlorethamine, Cyclophosphamide, Thiotepa, Methotrexate 4.2. Antimalarials: Chloroquine, Primaquine, Pyrimethamine.

Module: 5 (8 Hrs.)

5.1. Diuretics: Acetazolamide, Chlorthiazide, Furosemide, Disulfamide, Chlorthalidone, Ethacrynic acid, Mersalyl.

5.2. Structure of Some Drugs: Oesterone, Quinidine sulphate, Procainamide, Amiodarone, Mercaptomerin Sodium, Spironolactone, Triamterene, Losartan, Tolbutamide, Mepacrine mesylate, Melphalan.


1. Wilson & Grisvold, Text Book of Organic Medicinal & Pharmaceutical Chemistry, Lippincott Williams & Wilkins.

2. William Foye, Principles of Medicinal Chemistry, Lippincott Williams & Wilkins. 3. S.N.Pandeya, A Text Book of Medicinal Chemistry, SG Publisher, Varanshi. 4. Ashutosh Kar, Medicinal Chemistry, New Age International Publishers, New Delhi. 5. Bentley & Driver, Text Book of Pharmaceutical Chemistry, Oxford University Press, New

Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmacology- III Code: 341719(41)




Module: 1 Drugs Acting on the Gastrointestinal Tract (8 Hrs.)

1.1. Antacids, Anti secretory and Anti-ulcer drugs, Laxatives and antidiarrhoeal drugs. 1.2. Appetite stimulants and suppressants. 1.3. Emetics and anti-emetics. 1.4. Miscellaneous: carminatives, demulcents, protectives, adsorbents, astringents, digestives, enzymes and

mucolytics.

Module: 2 Pharmacology of drugs affecting Endocrine System (8 Hrs.)

2.1. Hypothalamic and pituitary hormones

2.2. Thyroid hormones and anti-thyroid drugs, calcitonin and Vitamin D. 2.3. Insulin, oral hypoglycemic agents 2.4. ACTH and corticosteroids

2.5. Androgens and anabolic steroids, Estrogens, progesterone and oral contraceptives.

Module: 3 Chemotherapy (8 Hrs.)

3.1. General principles of Chemotherapy. 3.2. Sulfonamides and Quinolones. 3.3. Penicillin, Cephalosporins, Tetracyclines, Amino glycoside antibiotics, Chloramphenicol and

Erythromycin

Module: 4 Chemotherapy of Infections (8 Hrs.)

4.1. Chemotherapy of malaria tuberculosis, leprosy, fungal diseases, viral diseases 4.2. Chemotherapy of malignancy and immunosuppressive agents

4.3. Antiprotozoal drugs and anthelmintics

Module: 5 Concepts of Clinical Pharmacology (8 Hrs.)

5.1. Clinical Trial studies 5.2. Preclinical Toxicity studies 5.3. Bioassay of Drugs and Biological Standardization. 5.4. Drug interactions

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7 th Branch: B.Pharmacy

Subject: Pharmacognosy- IV Code: 341710(41)




Module: 1 (08 Hrs.)

1.1. Studies of Traditional Herbal Drugs: Common vernacular names, botanical sources, morphology, chemical nature of chief constituents, pharmacology, categories and common uses and marketed formulations of following indigenous drugs:

Punarnava (Boerhavia diffusa), Shankhpushpi (Convolvulus microphylla), Lahsun (Allium sativum), Guggul (Commiphora mukul), Kalmegh (Andrographis peniculata), Tulsi (Ocimum sanctum), Valerian (Valerian officinalis), Artemisia (Artemisia annua), Chirata (Swertia chirata), Asoka (Saraca indica), Saffron (Crocus sativa), Shilajit, Brahmi ( Bacopa monnieri and Centella asiatica), Salai (Boswellia serrata), Giloe (Tinospora cordifolia) Amla (Embellica officinalis), Pipali (Piper longum).

1.1.1. Bhoamyalaki (Phyllanthus niruri), Stevia

Module: 2 (08 Hrs.)

2.1. Study of Herbal formulations: The holistic concept of drug administration in traditional systems of medicine.

2.2. Brief Introduction and principles of Ayurveda, Sidha, Unani, Chinese and Homeopathic systems of medicines.

2.3. Introduction to Herbal Pharmacopoeias /formulary with special reference to preparations like Aristas, Asava, Ghutika, Taila, Churna, Avaleha, Ghrita and Bhasms; Unani formulations like Majooms, Safoofs.

Module: 3 (08 Hrs.)

3.1. Systematic study of source, cultivation, collection, processing, commercial varieties, chemical constituents, substitutes, adulterants, uses, diagnostic macroscopic and microscopic features and specific chemical tests of following

3.1.1. Alkaloid containing drugs: Pyridine - Tobacco. Tropane: Belladonna and Withania Quinoline and isoquinoline: Cinchona and Opium. Indole : Ergot, Rauwolfia and Catharanthus. Imidazole: Pilocarpus Steroidal: Veratrum Alkaloidal amine: Ephedra Glycoalkaloid: Solanum.

3.1.2. Purines: Coffee, tea and cola. Module: 4 (06 Hrs.)

4.1. Role of medicinal and aromatic plants in national economy.

4.2. World wide trade in Medicinal plants & derived product. Tropane alkaloids containing drugs, Cinchona, Rauwolfia, Taxol, Digitalis, Liquorice, Papain, Ginseng, Aloe, Valerian, & plant laxatives.

4.3. Biological sources, preparation, identification tests and uses of the following enzymes: Diastase, papain, pepsin, trypsin, pancreatin.

Module: 5 (08 Hrs.)

5.1. Introduction, classification and study of different chromatographic methods (Column Chromatography, TLC, PC, HPTLC, GC and HPLC) and their applications in evaluation of herbal drugs.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Pharmaceutics-X (Pharmaceutical Technology -II) Lab. Code: 341725(41)




1. To formulate and evaluate Paracetamol / Aspirin tablets by different tabletting methods. 2. Prepare and evaluate Effervescent Tablets of Aspirin. 3. Prepare and evaluate dispersible tablets of Diclofenac Sodium. 4. Perform the sugar coating on the given sample of Tablets. 5. Perform the Film Coating on the given sample of Tablets. 6. Perform the enteric coating on the given sample of Tablets. 7. Prepare and evaluate Tetracycline HCL Capsules. . 8. Prepare and evaluate Ciprofloxacin Eye Drop. 9. Prepare and evaluate Water for Injection. 10. Prepare and evaluate Oxytetracycline Injection. 11. Prepare and evaluate an aqueous injection of poor water soluble drug using hydrotropic

solubilization technique. 12. Experiments to illustrate physical and biological evaluation of pharmaceutical products like powders,

surgical dressing. 13. To study the role of glidants on flow properties of granules. 14. To study the role of lubricant mixing on diminution profile of pharmaceuticals. 15. To study the rate of drying in static and in fluidized state. 16. To perform content uniformity by varying rate and time of mixing of powders. 17. To perform stability studies on drug formulations as per ICH guidelines.

Text Books / Reference Books (Latest Edition): 1. E. A. Rawlins, Bentley, Textbook of Pharmaceutics, Tindall, London, 8th Ed. 2005. 2. D. K. Tripathi, Introduction to Pharmaceutics (Theory and Practice), Jaypee Brothers Medical Publisher,

Pvt. Lt.d., New Delhi. 3. Lachmann & Libermann, Theory & Practice of Industrial Pharmacy, Varghese Publishing House,

Bombay. 4. Ansel, Allen & Popovich, Pharmaceutical Dosage Forms & Drug Delivery Systems, Lippincott Williams &

Wilkins, London, 5. Science & Practice of Pharmacy, Remington, Lippincott Williams & Wilkins, London. 6. M.E.Aulton, Pharmaceutics, “The Science of Dosage Form Design”, Churchil lLivingstone, New York.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Pharmaceutics-XI (Biopharmaceutics and Pharmacokinetics) Lab. Code: 341726(41)




1. To find out mean dissolution time (MDT) of given sample of tablet and compare with other marketed brands.

2. To find out Km, Vm of given drug in presence of various enzyme (papain and albumin). 3. To determine kinetic parameter of given drug (aspirin) by urinary excretion data. 4. To find out protein binding rate of given drug sample. 5. To estimate buccal absorption of given chewable tablet of ascorbic acid. 6. To perform bioequivalence study of given drug samples. 7. To perform In-vitro drug release study of Enteric Coated Aspirin tablet. 8. To perform In-vitro bio-equivalence study of different marketed suspension formulation of

paracetamol. 9. To perform In-vitro drug release study of conventional aspirin tablet. 10. To perform In-vitro drug release study of diclofenac sustain release tablet. 11. To perform In-vitro bioequivalence study of sustain Release formulation. 12. To determine the apparent permeability of drug using Cockrel Intestine.


1. M. Gibaldi and D. Perrier, Pharmacokinetics, Marcel Dekker Inc., NY 2. R.E. Notari, Biopharmaceutics and Pharmacokinetics-An Introduction, Lea & Febiger, New York. 3. Jaiswal, Brahmankar, Biopharmaquality and pharmacokinetics. 4. I.D. Leepeter, Pharmacokinetic analysis 5. Niazi, Textbook of Biopharmacokinetics and clinical pharmacokinetics. 6. Venkaateshwaruv, Biopharmaceutics and pharmacokinetics, phared puss, Hyderabad. 7. Wagner-pharmacokinetics for the pharma studies. 8. Dhachinamoorthi D: Biopharmaceutics and pharmacokinetics: A practical manual. 9. Shargel: Pharmacokinetics & Biopharmacokinetics & Biopharmaceutics. 10. A.R. Gennaro, ed Remington’s The science and Practice of Pharmacy, Mac Publishing Co.

Pennsylvannia, USA. 11. Milo Gibaldi. Biopharmacokinetics and Clinical Pharmacokinetics, 3rd., Lea & Febizer,

Philadelphia 1984. 12. Brahmankar’s Biopharmaceutics and Pharmacokinetics, Vallabh Prakashan, Delhi. 13. Rowland & Tozer’s Clinical Pharmacokinetics, Concepts and applications, Lea & Febiger Publication,

USA.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Pharmacology-III Lab. Code: 341727(41)




1. To calculate the pA2 value of atropine using acetylcholine as an agonist on rat ileum preparation. 2. To calculate the pA2 value of mepyramine or chlorpheniramine using histamine as agonist on guinea pig

ileum. 3. To estimate the strength of the test sample of Acetylcholine using a suitable isolated muscle preparation

employing Matching bioassay, Bracketing assay, three point assay and four point bioassay. 4. To estimate the strength of the test sample of Histamine using a suitable isolated muscle preparation

employing Matching bioassay, Bracketing assay, three point assay and four point bioassay. 5. To estimate the strength of the test sample of Oxytocin using a suitable isolated muscle preparation

employing Matching bioassay, Bracketing assay, three point assay and four point bioassay. 6. To study the Anti- secretary and anti-ulcer activity using pylorus ligation method. 7. To determine the MIC of antibiotics. 8. Study of OECD toxicity guidelines

Text Books / Reference Books (Latest Edition): 1. K.D. Tripathi, Essentials of Medical Pharmacology, JAYPEE. 2. Goodman and Gilman's, The Pharmacological basis of Therapeutics; Editors: J G Hardman, L E Limbird,

P B Molinoss, R W Ruddon and A G Gil, Pergamon Press." 3. Satoshkar and Bhandarkar, Pharmacology & Parmacotherapeutics, Popular Publication. 4. Rang MP, Dale MM, Riter lM., Pharmacology, Churchill Livingstone. 5. Crossland J and Thomson J H., Essentials of Pharmacology, Harper and Row Publishers NY 6. Craig C R and Stitzel R R, Modem Pharmacology, Little Brown and Company, 1994. 7. S.R Kale, R.R Kale and S.A Hasan, Practical Pharmacology and Toxicology. Nirali Prakashan, Latest

Edition. 8. S.K. Kulkarni., Handbook of Experimental Pharmacology, Vallabh Prakashan Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Pharmacognosy-IV Lab. Code: 341728(41)




1. Perform macroscopic study of at least ten indigenous crude drugs listed in theory.

2. Perform macroscopic study of at least five alkaloid containing crude drugs as mentioned in theory.

3. Formulation and Standardization of at least two traditional drug formulations (Ayurvedic/Unani).

4. Perform microscopic study of eight - selected drugs given in theory in entire and powdered form (two drugs in each experiment).

5. Perform chemical evaluation of powdered drugs.

6. Perform chemical evaluation of enzymes

7. Perform experiment to isolate papain from papaya.

8. Perform experiment to isolate nicotine from tobacco

9. Perform experiment to isolate withanolides from withania leaves.

10. Perform chromatographic studies of some herbal constituents by TLC and PC.

Text Books / Reference Books(Latest Edition):

1. C. K. Kokate, A.P.Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune. 2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier. 3. T.E.Wallis, Text Book of Pharmacognosy, CBS Publishers & Distributors, New Delhi. 4. V.E. Tyler, L.R. Brady & J.E. Robbers, Text Book of Pharmacognosy, Lea & Febiger, Philadelphia. 5. S.H. Ansari, Essential of Pharmacognosy, Birla Publication, Shahdara, New Delhi. 6. T. E. Wallis, Analytical Microscopy, J&A Churchill Limited, London. 7. K.R. Brain and T.D.Turner. “The Practical Evaluation of Phyto Pharmaceutical”, Wright, Scientechnica-

Bristol. 8. P, J. Schewer, Marine Natural products, Academic press, London. 9. Brain, K.R., & Turner T.D, The Practical evaluation of phytopharmaceutical, Wright, Bristol. 10. C. K. Kokate, Practical Pharmacognosy, Vallabh Prakashan, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 7th

Branch: B. Pharmacy

Subject: Industrial Training and report writing. Code: 341729(41)



Industry : Pharmaceutical manufacturing industry*

Duration: Minimum two weeks

* The original certificate issued by the industry where the training is under gone to be enclosed with

the report.

www.Pharmainfo.Net

www.Pharmainfo.Net


B. Pharmacy Forth Year,

EIGTH SEMESTER, (New) from 2012 – 13

S. No

Subject Code No.

Board of Studies

Subject

Periods Per Week


Total Marks


L T P ESE CT TA

1 341815(41) Pharmacy Pharmaceutics-XII (Pharmaceutical Technology –III) 4 1 - 70 20 10 100 5

2 341816(41) Pharmacy Pharmaceutical Analysis- III (Instrumental) 4 1 - 70 20 10 100 5

3 341817(41) Pharmacy Pharmaceutical Analysis- IV (Quality Assurance and Drug Regulatory Affairs )

4 1 - 70 20 10 100 5

4 341818(41) Pharmacy Pharmacognosy- V 4 1 - 70 20 10 100 5

5 341819(41) Pharmacy Pharmaceutics- XIII (Pharmaceutical Jurisprudence) 4 1 - 70 20 10 100 5

6 341825(41) Pharmacy Pharmaceutics-XII (Pharmaceutical Technology –III) – Lab - - 3 60 - 40 100 2

7 341826(41) Pharmacy Pharmaceutical Analysis- III (Instrumental) – Lab - - 3 60 - 40 100 2

8 341827(41) Pharmacy Pharmacognosy-V – Lab - - 3 60 - 40 100 2

9 341828(41) Pharmacy Project - - 3 120 - 80 200 2

TOTAL 20 5 12 650 100 250 1000 33



www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics -XII (Pharmaceutical Technology –III) Code: 341815(41)



Minimum number of class tests to be conducted: 2 Module: 1(8 Hrs.)

1.1. Introduction of Controlled and Extended drug delivery system. 1.2. Design, development, formulation and evaluation of controlled release formulations. Carriers for drug

delivery systems, Prodrugs.

Module: 2 (8 Hrs.)

2.1. Micro-encapsulation: Types of microcapsules, importance of microencapsulation in pharmacy, microencapsulation by phase separation, coacervation, multi orifice, spray drying, spray congealing, polymerisation complex emulsion, air suspension technique, coating pan and other techniques, evaluation of micro capsules.

Module: 3 (8 Hrs.)

3.1. Targeted Drug Delivery Systems: Concept of drug targetting, importance in therapeutics, methods in drug targeting, Nanoparticles, Liposomes, Erythrocytes.

3.2. Transdermal Drug Delivery Systems: Principle, types of components, application, method of preparation, evaluation parameters.

Module: 4 (8Hrs.)

4.1. Sustained release formulations: Concept, Rationale for Extended – Release Pharmaceuticals, Terminology, Techniques of Extended release oral dosage forms. Delayed - Release oral dosage forms, Evaluation of sustained release formulations. Brief introduction to controlled release dosage forms. Design and evaluation of osmotic pump, implants, IUDs and occuserts,

Module: 5 (8Hrs.)

5.1. Surgical products: Definition, primary wound dressing, absorbents, surgical cotton, surgical gauzes etc., bandages, adhesive tape, protective cellulosic hemostatics, official dressings, absorbable and non absorbable sutures, ligatures and catguts. Medical prosthetics and organ replacement materials.

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutical Analysis- III (Instrumental) Code: 341816(41) Total Theory Periods: 40 Total Tut. Periods: 12



Principle, basic instrumentation, elements of interpretation of spectra and applications of the

following analytical techniques should be discussed.

Module: 1 (8 Hrs.)

1.1. Ultraviolet and visible spectrophotometry. 1.2. Atomic Absorption spectroscopy

Module: 2 (8 Hrs.)

2.1. Infrared spectrophotometry. 2.2. Fluorimetry

Module: 3 (8 Hrs.) 3.1. Nuclear Magnetic resonance spectroscopy including C13 NMR. 3.2. Flame Photometry.

Module: 4 (8 Hrs.) 4.1. Mass Spectrometry 4.2. X-ray diffraction

Module: 5 (8 Hrs.)

5.1. Chromatography: The following techniques will be discussed with relevant examples of pharmacopoeial products.

5.1.1. TLC, Paper Chromatography, Ion exchange chromatography and Column Chromatography. 5.1.2. HPLC, GLC, and HPTLC

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8th Branch: B.Pharmacy

Subject: Pharmaceutical Analysis- IV (Quality Assurance and Code: 341817(41)

Drug Regulatory Affairs) Total Theory Periods: 40 Total Tut. Periods: 12



Module: 1 (8 Hrs.)

1.1. Quality Assurance 1.1.1. Basic concepts of Quality control & Quality Assurance, Total Quality Management, Philosophy of GMP, cGMP, GLP, ISO. Introduction of ICH guidelines 1.1.2. Regulatory control, regulatory drug analysis, interpretation of analytical data.

Module: 2 (8 Hrs.)

2.1. Pharmaceutical Validation 2.1.1. Process Validation, Equipment validation, Validation of Analytical Procedures. 2.1.2. Sterile products validation 2.1.3. Cleaning validation 2.1.4. Validation of Water systems for sterile & Non Sterile products

Module: 3 (8 Hrs.)

3.1. Quality control responsibilities, Routine controls on instruments, sampling plans, standard test procedures and protocols, Quality control documentation and audits of QC facilities. Finished product release, quality review, quality audits and batch release documents.

Module: 4 (8 Hrs.)

4.1. Drug Regulatory Affairs: Role of Regulatory Affairs Dept., Nomenclature and salient features of regulatory authorities of India, US, Japan and EU.

Module: 5 (8 Hrs.)

5.1. Stability testing protocols of drug products as per ICH guidelines.


1. How to Practice GMPs, Vandana Publications, Delhi. 2. D. H. Shab, Quality Assurance Manual,– Business Horizons

3. Quality Assurance for Pharmaceuticals, Vol-I & II, Pharma Book Syndicate

4. D.H. Shah, SOP Guidelines, Business Horizon, Delhi. 5. R.A. Nash & A.H. Wachter, Pharmaceutical Process Validation, Marcel Dekker, New York, 6. S. H. Wilig, Good Manufacturing Practices for Pharmaceutics, Marcel Dekker, New York.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8th

Branch: B. Pharmacy

Subject: Pharmacognosy- V Code: 341818 (41) Total Theory Periods: 40 Total Tut. Periods: 12


Minimum number of class tests to be conducted: 2 Module: 1 (8 Hrs.)

1.1. Isolation Techniques:

1.1.1. General methods used for the isolation and characterization of alkaloids, lipids, glycosides, proteins, volatile oils, bioflavonoids, steroids, terpenoids and resins.

1.1.2. Application of column, paper and thin layer chromatographic techniques for the isolation of phytopharmaceuticals.

Module: 2 (8 Hrs.)

2.1. Plant Biotechnology:

2.1.1. Tissue culture, Nutritional requirements, Callus and suspension culture. 2.1.2. Production of secondary metabolites, viz. Shikonin and Taxol. 2.1.3. Biotransformation, immobilisation of cells and enzymes. 2.1.4. Applications of plant tissue culture in pharmacognosy. Module: 3 (8 Hrs.)

3.1. Quality control and Standardization of herbal drugs:

3.1.1. WHO guidelines for evaluation of drugs 3.1.2. Factors affecting Herbs quality of herbal drugs 3.1.3. Chromatographic markers. 3.1.4. Spectroscopic techniques and assay methods. 3.1.5. Determination of heavy metals in herbal preparation like bhasmas and churanas 3.1.6. Determination of alcohol contents in Aristas and Asawas. 3.1.7. Quality control and rational use of herbal drugs as per WHO guidelines. 3.1.8. Deterioration of herbal drugs by insect.

Module: 4 (8 Hrs.) 4.1. Herbal cosmetics and novel phytopharmaceuticals:

4.1.1. Cosmeceuticals 4.1.2. Shampoos (soapnut), Conditioners, (Amla, Henna, Hibiscus, Tea), Hair darkeners (Amla, Henna), Skin

care (Aloe, Turmeric). 4.1.3. Phytosomes: Definition and scope 4.2. Marine pharmacognosy: An introduction to potential cardio-vascular, anticancer/cytotoxic and antibiotic drugs from marine sources. 4.3. Chemotaxonomy of medicinal plants.

4.4. Herbs as health foods (Nutraceuticals).

4.5. Antioxidants from plant origin

Module: 5 (8 Hrs.)

5.1. Extraction of herbal drugs:

5.1.1. Basic principle 5.1.2. Pre extraction operation for crude drugs 5.1.3. Effect of solvent, solvent mixture & solution of extraction 5.1.4. Extraction methods 5.1.5. Treatment of dry residue after extraction

www.Pharmainfo.Net

www.Pharmainfo.Net



Subject: Pharmaceutics- XIII (Pharmaceutical Jurisprudence) Code: 341819(41) Total Theory Periods: 40 Total Tut. Periods: 12


Minimum number of class tests to be conducted: 2 Module: 1 (8 Hrs.) 1.1. Introduction: Pharmaceutical Legislations–A brief review; Pharmaceutical Education-A brief review;

Code of Pharmaceutical Ethics.

Module: 2 (8 Hrs.) 1.1. An elaborate study of the followings: Pharmacy act 1948, Drugs and Cosmetics Act 1940 and Rules

1945, Narcotic Drugs & Psychotropic Substances Act 1985 & Rules.

Module: 3 (8 Hrs.) 3.1. A brief study of the following with special reference to the main provisions only: Poisons Act

1919, Medical Termination of Pregnancy Act 1970 & Rules 1975.,Prevention of Cruelty of Animals Act 1960.

Module: 4 (8 Hrs.) 1.1. Patents Act 1970: Objective, definition and type of patent, secrecy of certain inventions, procedure for

getting patent. 1.2. Factories Act 1948: approval, licensing and registration of factory, inspection, design of work hour 1.3. Medicinal & Toilet Preparations (Excise Duties) Act 1955.

Module: 5 (8 Hrs.) 5.1. Drugs Price Control Order 1995: Objective and calculation of retail price of formulation. 5.2. Drugs and Magic Remedies (Objectionable Advertisements) Acts 1954.


1. B.M. Mithal, A Textbook of Forensic Pharmacy, Vallabh Prakashan, New Delhi, 2. N.K. Jain, A Textbook of Forensic Pharmacy, Vallabh Prakashan, New Delhi. 3. V. Malik, Law relating to Drugs & Cosmetics, Eastern Book Com.,Lucknow.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8th

Branch: B. Pharmacy

Subject: Pharmaceutics-XII (Pharmaceutical Technology -III ) Lab. Code: 341825(41)




1. To formulate and evaluate sustain release matrix tablets of Diclofenac sodium. 2. To formulate and evaluate Transdermal patch of diclofenac sodium/salbutamol sulphate. 3. To microencapsulate diclofenac sodium by solvent Evaporation Technique. 4. To formulate solid dispersion of poorly water soluble drug using kneading method. 5. To formulate solid dispersion of poorly water soluble drug by solvent evaporation technique. 6. To formulate and evaluate the liposome prepared by thin film hydration hand shaking method. 7. To prepare and evaluate microcapsules 8. To prepare and evaluate transdermal patches 9. To prepare and evaluate solid dispersion tablets 10. To prepare and evaluate microspheres prepared by coacervation method and emulsification method. 11. To study the release profile of conventional and enteric coated tablets. 12. To study the effect of rate of stirring on size of microspheres. 13. To study the effect of cross linking agent on microspheres. 14. Evaluate various surgical products.

Text Books / Reference Books (Latest Edition): 1. J.R. Robinson & Lee Vincent, Controlled Drug Delivery: Fundamentals & Applications, Marcel Dekker

Inc., NY. 2. Pharmacopoeia of India, Ministry of Health and family Welfare, Govt. of India, New Delhi. 3. Banker G.S. and Rhode C.T., Modern Pharmaceutics, Marcell Decker Inc., New York. 4. N. K. Jain Controlled and novel drug delivery; CBS Publishers, Delhi. 5. N.K. Jain, S. N. Sharma, Advances in Controlled & Novel Drug Delivery, CBS Publishers, Delhi. 6. E. A. Rawlins, Bentley, Textbook of Pharmaceutics, Tindall, London, 8th Ed. 2005. 7. Lachmann & Libermann, Theory & Practice of Industrial Pharmacy, Varghese Publishing House,

Bombay. 8. Ansel, Allen & Popovich, Pharmaceutical Dosage Forms & Drug Delivery Systems, Lippincott Williams &

Wilkins, London, 9. Science & Practice of Pharmacy, Remington, Lippincott Williams & Wilkins, London. 10. M.E. Aulton, Pharmaceutics, “The Science of Dosage Form Design”, Churchil lLivingstone, New York.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8th

Branch: B. Pharmacy

Subject: Pharmaceutical Analysis-III (Instrumental Analysis) Lab. Code: 341826(41)




1. Estimation of Na+, K+, Ca++ ions using flame photometry. 2. Workshop to interpret the structure of simple organic compounds using UV, IR, NMR & MS 3. Determination of solvent cut off value of different solvents. 4. Study of effect of various solvents on spectral features of any drug. 5. Perform the quantitative spectrophotometric estimation of drug by single point method. 6. Perform the quantitative spectrophotometric estimation of drug by calibration curve method. 7. Perform the quantitative spectrophotometric estimation of drug by standard absorptivity method. 8. Simultaneous quantitative spectrophotometric estimation of two drugs by simultaneous equation method. 9. Simultaneous quantitative spectrophotometric estimation of two drugs by dual wavelength method. 10. Simultaneous quantitative spectrophotometric estimation of two drugs by derivative spectroscopy. 11. To determine the drug content of given tablet formulation 12. Interpretation of given IR spectra. 13. Chromatographic analysis of some pharmaceutical products, (Paper chromatography of Amino acids,

TLC of alkaloids, sulphonamides) 14. Quantitative estimation of any drug by RP-HPLC. 15. Acid and alkaline stress degradation study of any drug. 16. Photo and thermal stress degradation study of any drug. 17. Oxidative stress degradation study of any drug.

Text Books / Reference Books (Latest Edition): 1. Vogel, Text Book of Quantitative Chemical Analysis, Pearson Education. 2. B.K. Sharma, Instrumental Methods of Chemical Analysis, Goel Publishing House. 3. Beckett & Stenlake, Practical Pharmaceutical Chemistry, Vol.-II, CBS Publishers & Distribution. 4. Corner, A Text Book of Pharmaceutical Analysis, John Wiley. 5. Willard Den & Merrit, Instrumental Methods of Analysis, CBS Publication & Distribution.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8th

Branch: B. Pharmacy

Subject: Pharmacognosy-V( Lab) Code: 341827(41)




1. Isolation of some selected phytoconstituents studied in theory.

2. Extraction of volatile oils and their chromatographic profiles.

3. Some experiments in plant tissue culture.

4. Preparation and evaluation of herbal Cosmetics ( atleast one from theory).

5. Perform experiment to demonstrate antioxidant activity by DPPH method / H2O2 method

6. Determination of solvent extractive values (water/alcohol).

7. Determination of ash values.

8. Determination of volatile oils in crude drugs.

9. Determination of specific microorganism in crude drugs.(salmonella\staphylococcus)

10. Determination of bitterness value.

11. Determination of hemolytic activity.

12. Determination of foaming index and swelling index.

13. Determination of tannins.

14. Determination of heavy metals by limit test /instrumental analysis of (As/Hg/Pb/Cd)


1. C. K. Kokate, A.P. Purohit, S.B. Gokhale, Text Book of Pharmacognosy, Nirali Prakashan, Pune. 2. G.E. Trease & W.C. Evans, Pharmacognosy, Saunders Elsevier. 3. T.E. Wallis, Text Book of Pharmacognosy, CBS Publishers and Distributors, New Delhi. 4. V.E. Tyler, L.R. Brady & J.E. Robbers, Text Book of Pharmacognosy, Lea & Febiger, Philadelphia. 5. S.H. Ansari, Essential of Pharmacognosy, Birla Publication, Shahdara, New Delhi. 6. T. E. Wallis, Analytical Microscopy, J&A Churchill Limited, London. 7. K.R. Brain and T.D. Turner. “The Practical Evaluation of Phyto Pharmaceutical”, Wright, Scientechnica-

Bristol. 8. C. K. Kokate, Practical Pharmacognosy, Vallabh Prakashan, New Delhi. 9. Quality control methods for medicinal plant materials, World Health Organisation, Geneva, AITBS

Publishers and Distributors, Delhi. 10. Sagarin & Balsam M.S. Cosmetic Science and Technology, Vol 1-3, John Wiley & Sons, NY. 11. S. Saraf & S. Saraf, Cosmetics: A Practical Manual, Pharma Book Syndicate.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 8 th Branch: B. Pharmacy

Subject: Project Code: 341828(41) Total Marks in End Semester Examination: 200

The project should be based on the subject taught during the course.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY

B. Pharma First Year

FIRST SEMESTER

Scheme of Examination Periods Per

Week Theory Practical S.No

Subject No.

Board of Studies

Subject

L P ESE CT TA ESE TA

Total Marks

Credit = [L+[T+P]]

2

1 341111(41) -A 341111(41)-B Pharmacy Remedial Mathematics OR

Remedial Biology 5

-

70

15

15

-

-

100

5

2 341112 (41) Pharmacy

Computer Applications 5 - 70 15 15 - - 100 5

3 341113 (41) Pharmacy

Pharmaceutics-I (Introduction to Pharmaceutics) 5 - 70 15 15 - - 100 5

4 341114 (41) Pharmacy

Pharmaceutical Chemistry-I (Physical) 5 - 70 15 15 - - 100 5

5 341115 (41) Pharmacy

Pharmaceutical Chemistry –II (Inorganic) 5 - 70 15 15 - - 100 5

6 341121 (41) Pharmacy

Remedial Biology Practicals - 3 - - - 60 40 100 2

7 341122 (41) Pharmacy

Computer Application Practicals - 3 - - - 60 40 100 2

8 341123 (41) Pharmacy

Pharmaceutics-I (Introduction to Pharmaceutics) Practicals - 3 - - - 60 40 100 2

9 341124 (41) Pharmacy

Pharmaceutical Chemistry- I (Physical) Practicals - 3 - - - 60 40 100 2

10 341125 (41) Pharmacy

Pharmaceutical Chemistry –II (Inorganic) Practicals - 3 - - - 60 40 100 2

TOTAL 25 15 350 75 75 300 200 100

0 35

Min. Pass Marks : (A) Theory ESA & TA+CT (Combined) : 50% , (B) Practical ESE & TA (Combined ): 50%

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Computer Applications CODE : 341112 (41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70

MINIMUM NO. OF CLASS TESTS TO BE CONDUCTED

: 2

Branch: Pharmacy I Semester Course: Computer Applications (Theory) History of computer development and respective generation: Abacus, Napier, Bone, Slide rule, PASCAL'S, Calculator. Need to use computers, applications in pharmacy and in general. Computer Classification: Mainframe, Mini and Micro Computers, Comparison of Analogue and Digital Computers, Hardware and Software, Calculator and Computer. Operating Systems: Introduction to types of operating systems, UNIX, MS-DOS etc. RAM, Virtual Memory etc. Tvpe of Languages: Conventional languages; their advantages, limitations; C, PASCAL, FORTRAN, programming of these languages. Introduction to Computer Networks: Architecture of seven layers of communications. Introduction to Data Structure: Like Queues, List, Trees. Binary trees algorithms, Flow chart, Structured system, Analysis and development, Ingress-SQL, Gateways etc. Statistics, Methodologies. Basic Language:

Constants and Variables-Character se':, constant, variables, Naming the variables getting data into memory, LET, INPUT, READ, DATA, prin1 statement. Expression:

Arithmetic expression, Hierarchy of operations, Rules of Arithmetic, Evaluation of expressions, Relational expressions, Logical operations, Library function. Printer Control: Comma and semicolon control, the TAB function, PRINT, LPPRINT. Computer graphics Computer applications in pharmaceutical and clinical studies.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL

UNIVERSITY, BHILAI SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Pharmaceutical

Chemsitry CODE : 341114(41)

TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70

MINIMUM NO. OF CLASS TESTS

TO BE CONDUCTED : 2

Branch: Pharmacy I Semester Course: Pharmaceutical Chemistry-I (Physical) Behavior of Gases Kinetic theory of gases, deviation from ideal behavior and explanation. The Liquid State Physical properties of drug molecule (surface tension, parachor, viscosity, refractive index, optical rotation, dipole moments and chemical constituents). Solutions Ideal and real solutions, solutions of gases in liquids, colligative properties, partition coefficient, conductance and its measurement, Debye Huckel Theory. Thermodynamics First, Second and Third laws, Zeroth law, absolute temperature scale, thermo chemical equations, phase equilibrium and phase rule. Adsorption Frendlich and Gibbs's adsorption isotherms, Langmuir theory of adsorption. Photochemistry Consequences of light absorption, lablenski diagram, Lambert Beer laws, Quantum efficiency. Chemical Kinetics Zero, First and Second order reaction, complex reactions, theories and reaction kinetic characteristics of homogeneous and heterogeneous catalysis, acid-base enzyme catalysis. Quantum Mechanics -

Postulates of quantum mechanics, operators in quantum mechanics, Schrodinger wave equation.

I-P-4 PHARMACEUTICAL CHEMISTRY-I (PHYSICAL) PRACTICALS

Experiments based on theory.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Pharmaceutical

Chemsitry CODE : 341115(41)

TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM

EXAM : 70


: 2

Branch: Pharmacy-1 Semester Course: Pharmaceutical Chemistry (Inorganic) (Theory) An outline of methods of preparation, uses, sources, of impurities, test for purity and identity including limit tests for iron, arsenic, lead, heavy metals, chloride, sulphate and special tests if any, of the following classes of ir:0rganic pharmaceuticals listed in Indian Pharmacopoeia.

1) Acids and Bases: Buffers, Water. 2) Gastrointestinal Agents: Acidifying agents, Antacids, Protectives, and Absorbents,

Cathartics. 3) Major Intra and Extra Cellular Electrolytes: Physiological cations, Electrolytes used for

replacement therapy, acid-base balance and combination therapy. 4) Essential and Trace Elements: Transition elements and their compounds of

pharmaceutical importance, Iron and haematinis, Mineral supplements. 5) Cationic and in anionic components of inorganic drugs useful for systemic effects. 6) Topical Agents: Protectives, Astringents and Anti infectives. 7) Gases and Vapours: Oxygen, Anesthetics and respiratory stimulants. 8) Dental Products: Dentifrices, anti-caries agents. 9) Complexing and chelating agents used in therapy. 10) Miscellaneous Agents: Sclerosing agents, expectorants, emetics, poisons and .

antidotes, sedatives etc., pharmaceutical aids used in pharmaceutical industry antioxidants, preservatives, diluents, excipients, suspending agents, colorants, filter aids, adsorbents etc.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Phamaceutics CODE : 341113(41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70


: 2

Branch: Pharmacy I Semester Course: Pharmaceutics-I (Introduction To Pharmaceutics) (Practical) History of pharmaceutical practice through ages, Pharmacy as a career, Pharmacy in relation to allied health profession. Various systems of medicines, Pharmacopoeias with special reference to Indian, British, United States: International and Extra Pharmacopoeias. Routes of drugs administration, classification of pharmaceutical dosage forms. Definition, general formulation, manufacturing procedures and official products of Aromatic waters, Solutions, Syrups, Spirits, Elixirs, Linctuses, Lotions, Liniments, Glycerites, Gargles, Mouthwashes, Inhalations, Emulsions, Suspensions, Milks and Magmas, Mucilages, Jellies, Infusion, Decoctions, Tinctures and Extracts. Detailed methods employed in the preparation of plant extractives. Pharmaceutical Calculations: Different systems of weights and measures, Dilution and concentration of Solutions, Percentage solutions, Calculation by allegation, Proof spirits.

I-P-3 PHARMACEUTICS-I (INTRODUCTION TO PHARMACEUTICS) PRACTICALS

Classes mentioned under theory.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Remedial Biology CODE : 341111 (B) (41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70


: 2

Branch: Pharmacy I Semester Course: Remedial Biology Classification of Plants -

1) Structure of plant, cell, Mitosis and Meiosis, Different types of plant tissues and their functions. Simple and compound microscopes use in biology.

2) Morphology and Histology of root, stem, bark, wood, leaf, flower, fruit and seed. Modification of root and stem.

3) Study of the following families with special reference to medicinally important plants – Apocynacea Solanaceae, Graminae, Labiatae, Cruciferae, Papaveraceae, Umbellileral, Leguminosae, Rubiaceae anc Liliaceae.

4) Classification and General survey of Animal Kingdom. 5) Structure and life history of parasites like Amoeba, Entamoeba, Trypnosoma,

Plasmodium, Taeniaan . Ascaris.General structure and life history of insects like Mosquito and Housefly.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Remedial Mathematics CODE : 341111(A)(41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70


: 2

Branch: Pharmacy I Semester Course: Remedial Mathematics Algebra -

Equation reducible or quadratics, Simultaneous equations (liner and quadratic) determinations, properties of, Solution of simultaneous equations by Cramer's rule, Matrices, Definition of special kinds of matrices, Arithmetic operations on matrices, Matrices, Inverse of a matrix, Solution of simultaneous equations by matrices, Pharmaceutical applications of determinates and matrices. Evaluation on Enl, En2 and En3.Mensuration and its pharmaceutical applications measures of Central Value Objectives and pre-requisites of and ideal measures, mean. mode and median. Trigonometry Measurement of angel, T-ratios, Addition, Subtraction, and Transformation formulae, T -ratios of multiple, Submultiples, Allied and certain angles. Applications of 10garith...'"11s in pharmaceutical computations. Analytical Plane Geometry Certain co-ordinates, distance between two points, area of triangle, a locus of point, straight line; slope and intercept form, double-intercept form, normal (perpendicular form), slope-point and two point form, general equation of first degree. Calculus

Differential: Limits and functions, definition of differential coefficient, differentiation of standard functions including function of a function (chain rule). Differenti.3.tion of implicit functions, logarithmic differentiation, parametric differentiation, successive differentiati0n. Integral: Integration as inverse of differentiation, indefinite integrals of standard forms, integration by parts, substitution and partial fractions, formal evaluation of definite integrals.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 1st BRANCH : B.PHARMA SUBJECT : Computer Application

(Practical) CODE : 341122 (41)


EXAM : 60


:

Branch: Pharmacy I Semester Course: Computer Applications (Practical) Exercises based on the following are to be dealt :

1) Computer operating system like UNIX, MS-DOS etc. 2) Programming of languages – C, PASCAL and FORTRAN. 3) Study of software packages like WORDSTAR, LOTUS - 123

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY

B. Pharma First Year

SECOND SEMESTER

Scheme of Examination Periods Per

Week Theory Practical S.No

Subject No.

Board of Studies

Subject

L P ESE CT TA ESE TA

Total Marks

Credit = [L+[T+P]] 2

1 341211 (41) Pharmacy Advance Mathematics 5 - 70 15 15 - - 100 5

2 341212 (41) Pharmacy Pharmaceutics-II (Physical Pharmacy) 5 - 70 15 15 - - 100 5

3 341213 (41) Pharmacy Pharmaceutical Chemistry –III (Organic) 5 - 70 15 15 - - 100 5

4 341214 (41) Pharmacy Pharmacognosy-I 5 - 70 15 15 - - 100 5

5 341215 (41) Pharmacy Anatomy Physiology and Health Education -I 5 - 70 15 15 - - 100 5

6 341221 (41) Pharmacy Pharmaceutics –II (Physical

Pharmacy) Practicals - 3 - - - 60 40 100 2

7 341222 (41) Pharmacy Pharmaceutical Chemistry –III

(Organic –I) - 3 - - - 60 40 100 2

8 341223 (41) Pharmacy Pharmacognosy-I (Practicals) - 3 - - - 60 40 100 2

9 341224 (41) Pharmacy Anatomy, Physiology and Health Education –I Practicals - 3 - - - 60 40 100 2

10 341225 (41) Pharmacy Pharmaceutical Field Work

(Survey) - 3 - - - 60 40 100 2

TOTAL 25 15 350 75 75 300 200 1000 35 Min. Pass Marks : (A) Theory ESA & TA+CT (Combined) : 50% , (B) Practical ESE & TA (Combined ): 50% Each Periods is of 50 Minutes

www.Pharmainfo.Net

www.Pharmainfo.Net


UNIVERSITY, BHILAI SEMESTER : 2nd BRANCH : B.PHARMA SUBJECT : Anatomy, Physiology

and Health Education CODE : 341215(41)

TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70


: 2

Branch: Pharmacy II Semester Course: ANATOMY, PHYSIOLOGY AND HEALTH EDUCATION-I Scope of anatomy and physiology and basic terminology used in these subjects. Structure of cell, its components and their functions : Elementary Tissues of the Human Body

Epithelial, connective, muscular and nervous, tissues; their sub-types and characteristics. Gaseous System

Structure, composition and functions of skeleton, Classification of joints, Types of movement at joints, disorders of joints. Skeletal Muscles

Their gross anatomy, physiology of muscle contraction, physiological properties of skeletal muscle and their disorders. Haemopoietic System

Composition and functions of blood and its elements, their disorders, blood groups ,and their significance, mechanism of cc agulation; disorders of platelets and coagulation. Lymph and Lymphatic System

. Composition, formation and circulation of lymph ; disorder of lymp and lymphatic system. Basic physiology and function of spleen. Cardiovascular System

Basic anatomy of the heart, physiology of heart, blood vessels and circulation. Basis understanding of cardiac cycle, heart sounds and electrocardiogram. Blood pressure and its regulations. Brief outline of cardiovascular disorders like; hypertension, hypotension, arteriosclerosis angima, myocardial infraction, congestive heart failure and cardiac arrhythmias. Health Education . –

1. Concepts of health and diseases, disease agents and prevention of diseases. 2. Classification of food requirements, balanced diet, nutritional deficiency disorders,

their treatment and prevention. 3. Demography and family planning : Demography cycle, family. Meaning various

contraceptive methods. Medical termination of pregnancy. 4. First Aid Emergency treatment of shock, snake bites, burns, poisoning, fractures and

resuscitation methods.

II-P-S ANATOMY, PHYSIOLOGY AND HEALTH EDUCATION-I PRACTICALES

??Study of human skeleton. ??Study of different systems with the help of chart:, and models ??Microscopic study of different tissues.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 2nd BRANCH : B.PHARMA SUBJECT : Pharmaceutical

Chemistry CODE : 341213(41)


EXAM : 70


: 2

Branch: Pharmacy-II Semester

Course: PHARMACEUTICAL CHEMISTRY-III (ORGANIC-I) (Theory) Structure and Properties

Atomic structure, Atomic orbital, Molecular orbital theory, Wave equation, Molecular orbital, Bonding and ant bonding orbital, Covalent bond, Hybrid orbital, Intermolecular forces, Bond dissociation energy polarity of bonds, Polarity of molecules, Structure and physical properties, Acids and Bases. Stereochemistry

Isomerism and nomenclature any associated physicochemical properties, Optical activity. Stereo isomerism, specification of configuration, Reactions involving Structure Nomenclature, Preparation and Reaction of : Alkanes, Alkenes, Alkynes. Cycloalkanes, dienes, Benzene, involving stereoisomer, Confirmations. Carboxylic acids, Functional derivatives of carboxylic acids, Reaction intermediates – Carbotations, Carbanions, Carbenes, Nitrene and Nitrenium ions.

II-P-3 PHARMACEUTICAL CHEMISTRY-III (ORGANIC-I) PRACTICALS

??Identification of organic compounds and their derivative. ??Preparation of selected organic compounds ??Introduction to the use of stereo models.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 2nd BRANCH : B.PHARMA SUBJECT : Pharmacognosy CODE : 341214(41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM

EXAM : 70


: 2

Branch: Pharmacy II Semester Course : PHARMACOGNOSY-I (Theory) Definition, history,. scope and development of Pharmacognosy. Sources of crude drugs and methods of their classification: Cultivation, collection; processing and storage of crude drugs. Factors affecting cultivation of medicinal Plant hormones and their applications. Influence of polyploidy mutation and hybridization with reference to medicinal plants. Pest control and natural pest control agents. Quality Control of Crude Drugs: Different types of Adulteration and their evaluation using various methods like Organoleptic, Microscopic, Physical, Chemical, and Biological. An introduction of various types of primary and secondary metabolites as active constituents of crude. General methods of their isolation, classification, properties and systematic pharmocognositc study of

1. Carbohydrates, and drugs belonging to this class like; Agar, Gaur gum, Acacia, Honey, Isagpol, Strach, Sterculia, Tragacanth.

2. Lipids and drugs belonging to this class likes; Castor oil, Beeswax, Cocoa butter, Hydnacarpus oil, kokum butter, Cod-liver oil, wool fat.

3. Resins and Tannis and drugs belonging to this class like; podophyllu, Balsam, Turmeric, Ginger, Ipomoea, Myroballan.

4. Pharmaecutical aids like, Talc, Kaolin, Bentonite, Gelatin, Cotton, Viscose rayon. I. Evaluation of crude drugs mentioned in theory using morphology, micrc.scopy (both in whole and powdered forms as available), chemical tests for general and specific constituents. 2. Study of fibers and pharmaceutical aids.

II-P-4 PHARMACOGNOSY-I PRACTICALS

1. Evaluation of crude drugs mentioned in theory using morphology, microscopy (both in

whole and powdered forms as available) chemical tests for general and specific constituents.

2. Study of fibers and pharmaceutical aids.

www.Pharmainfo.Net

www.Pharmainfo.Net


UNIVERSITY, BHILAI SEMESTER : 2nd BRANCH : B.PHARMA SUBJECT : Pharmaceutics CODE : 341212(41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM EXAM

: 70

MINIMUM NO. OF CLASS TESTS

TO BE CONDUCTED : 2

Branch: Pharmacy-II Semester Course : Pharmaceutics (Physical Pharmacy) (Theory ) Matter: State and Selected Properties

State of matter, change in the state of matter, latent heats and vapour pressure, Sublimation: Critical I point, Eutectic, mixtures, gases, Aerosol: Inhalers, relative humidity, liquid complexes, liquid crystals, glassy state, Solids : Crystalline and amorphous; polymorphism. Micromeritics and Powder Rheology –

Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle volume, optical microscopy, sieving, sedimentation, particle shape, specific surface, methods for determining surface area, Derived properties of powders: Porosity, packing arrangement, densities, bulkiness and flow properties. Surface and Interfacial Phenomenon

Newtonian Systems : Law of flow, kinematics viscosity; effect of temperature, Non-Newtonian Systems; pseudoplastic, dilatent and plastic flow, Thixotropy, measurement of thixotropy, thixotropy formulation, Determination of viscosity, capillary, falling ball, rotational viscometers. Dispersed Systems – Colloidal Dispersion : : Definition, types, properties of colloids, protective colloids, application of colloids in Pharmacy. Suspensions and Emulsions : Interfacial properties of suspended particles, Setting in suspensions, Sedimentations parameters, Wetting of particles, Controlled flocculation. Flocculation in structured vehicles. Emulsions : Types, Theories and Physical stability. Complexation : Classification of complexes, Methods of preparation and analysis, Pharmaceutical applications. Kinetics and Drug Stability –

General considerations and concepts, half-life determination, Influence of temperature, light, solvent, catalytic, species and other factors, Accelerated stability study, expiration dating. Buffers –

Buffer equation and buffer capacity, buffers in pharmaceutical systems, buffered isotonic, solutions, measurement of tonicity calculations, method of adjusting isotonicity. II-P-2 PHARMACEUTICS – II (PHYSICAL PHARMACY) PRACTICALS

Experienced based on theory.

www.Pharmainfo.Net

www.Pharmainfo.Net


SEMESTER : 2nd BRANCH : B.PHARMA SUBJECT : Advanced Mathematics CODE : 341211(41) TOTAL THEORY PERIODS : 40 TOTAL TUT. PERIOD : 1 TOTAL MARKS IN END SEM

EXAM : 70


: 2

Branch : Pharmacy II Semester Course : Advanced Mathematics Differential equations –

Revision of integral calculus, definition and formation of differential equations, equations of first order and first degree, variable separable, homogeneous and linear differential equations and equations reducible to such types, linear differential equations of order greater than one with constant coefficients, complementary function and particular integral, simultaneous linear differential equations, pharmaceutical equations. Laplace Transforms –

Definition, transforms of elementary functions, properties of linearity and shifting, inverse laplace transforms of derivatives, solution of ordinary and simultaneous differential equations. Biometrics –

Significant digits and rounding of numbers, data collection, random and non-random sampling methods, sample size, data organization, diagrammatic representation of data, bar, pie, 2-D and 3-D diagrams, measures of central tendency, measures of dispersion, standard deviation and standard errors of means, coefficient of variation, confidence (fiducial) limits, probability and events, Bayes theorem, probability theorems, probability distributions, elements of binomial and poisson distribution, normal distribution curve and properties, kurtosis and skewness, correlation and regression analysis, methods of least squares, statistical inference students and paired t-test, f-test and elements of ANOVA, applications of statistical concepts in Pharmaceutical Sciences.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY, BHILAI Course of Study and Scheme of Examination

Bachelor of Pharmacy

III-Semester

Periods Per

Week

Scheme of Exam

Theory / Practical

S.No. Board of

Study

Subject

Code

(New)

Nomenclature and Name

of the Subject

L T P ESE CT TA Total

Marks

Credits

L+(T+P)/2

1 Pharmacy 341311(41) Pharmaceutics-III

(Pharmaceutical Engineering –I) 4 1 0 70 20 10 100 5

2 Pharmacy 341312(41) Pharmaceutics – IV (Dispensing

and Community Pharmacy) 4 1 0 70 20 10 100 5

3 Pharmacy 341313(41) Pharmaceutical Chemistry – IV

(Organic – II) 4 1 0 70 20 10 100 5

4 Pharmacy 341314(41) Anatomy, Physiology and Health

Education –II 4 1 0 70 20 10 100 5

5 Pharmacy 341315(41) Pharmacognosy – II 4 1 0 70 20 10 100 5

6 Pharmacy 341321(41) Pharmaceutics-III (Pharmaceutical

Engineering - I) Practical 0 0 3 60 - 40 100 2

7 Pharmacy 341322(41) Pharmaceutics –IV (Dispensing

and Community Pharmacy)

Practical

0 0 3 60 - 40 100 2

8 Pharmacy 341323(41) Pharmaceutical Chemistry –IV

(Organic II) Practical 0 0 3 60 - 40 100 2

9 Pharmacy 341324(41) Anatomy, Physiology and Health

Education –II Practical 0 0 3 60 - 40 100 2

10 Pharmacy 341325(41) Pharmacognosy – II Practical 0 0 3 60 - 40 100 2

Total 20 5 15 650 100 250 1000 35


Minimum Pass Marks: Duration of Theory Papers: 3 Hours.

(A)Theory and Sessional (combined): 50 Percent

(B) Practical and Sessional (combined): 50 Percent

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY,

BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Pharmaceutics- III (Pharmaceutical Engineering-I) Code: 341311(41)


Total Marks in End Semester Exam: 70

Minimum no. of class tests to be conducted: 2

Unit Operation- Unit operations and processes, Material and energy balances, Dimensionless equations; formulas and

groups.

Materials of Pharmaceutical Plant Construction- Factors affecting the material selection for pharmaceutical plants, Physical; Chemical; Mechanical

properties and use of the important materials of construction with special reference to Ferrous metals,

Copper, Aluminium, Nickel, Glass, Plastics and their alloys, Heat and Corrosion resistant alloys.

Corrosion and its Prevention - General considerations, Types of Corrosion, Methods of reducing Corrosion, Simple mathematical

problems.

Industrial Hazards and Safety Measures - Mechanical, Chemical, Electrical, Fire and Dust Hazards, Safety requirements, Legal requirements,

Industrial dermatitis.

Fluid Flow - Fluid static, Manometers, Types of flow, Reynold’s Number and its significance, Concept of

boundary layers, Bernoulli’s theorem and its applications, Measurement of flow of fluids, Valves.

Material Handling Systems - a) Liquid handling: Different types of pumps.

b) Solid handling: Conveyors.

Heat Transfer - Heat transfer mechanisms, Heat transfer by conduction, Fourier’s law, Natural and forced convection,

Surface and overall heat transfer coefficients, Heat transfer by radiation, Heaters and heat exchangers.

Humidity, Air-Conditioning and Refrigeration - Basic concepts and definitions of various terms. Psychrometric charts, Wet bulb theory, Measurement

of humidity. Application of humidity measurement, air-conditioning and refrigeration in Pharmacy.

Automated Process Control Systems: Process variables, Temperature, Pressure, Flow, Level and Vacuum and their

measurements.

Elements of computer aided manufacturing (CAM).

Reference / Recommend Books: 1. Khanna NK - Pharmacy Practicals – (CBS, ND)

2. Paradkar - T.B. of Pharma Engg. (Nirali Prakashan)

3. Brown - Unit operations in Chemistry Engg.(TMH)

4. Badger/ Banchow - Chemical Engineering (TMH)

5. GHOSHLK - HB of pharmaceutical Technology (CBS, New Delhi)

6. Sambamurthy - Pharmaceutical Engg. (Vallabh)

7. Subrahmanayam - Pharma Engg. (Vallabh)

8. Paradkar - Practical Pharma Engg. (Nirali)

9. Jeevan Jyothi - Practical Manual of Pharma Engg. (Nirali)

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Pharmaceutics- IV (Dispensing And Community Pharmacy) Code: 341312(41)




Prescription: Prescription, Handling of prescription, Source of errors in prescription, Care required in dispensing

prescriptions. Brief introduction of commonly used Latin terms in prescription.

General Dispensing Procedures including labelling of dispensed products. Principles involved and procedures adopted in dispensing of typical prescriptions-Solutions,

Mixtures, Emulsions, Lotions, Liniments, Powders, Capsules, Tablet triturates, Ointments, Creams,

Pastes, Suppositories and Ophthalmics.

Incompatibilities: Physical, Chemical and Therapeutic incompatibilities, Incompatibility of common occurrence and

their correction.

Pharmaceutical Calculations – Basis of posology, Detection of over doses in prescription, knowledge of prophylactic and therapeutic

doses with route of administration.

Calculation of doses, Enlarging and reducing receipes, Isotonic solutions,

Displacement value.

Community Pharmacy - Organization and structure of retail and wholesale drug stores, Legal requirements for establishment

and maintenance. Dispensing of proprietary products, Maintenance of records of retail and

wholesaler, Patient counseling, Role of Pharmacist in community health care and education, Hazards

of medication, Life-saving practices.

A brief study of proprietary products available in the market belonging to Chemotherapeutics,

Vitamins; Anti-histaminics, expectorants and NSAID’S category.

A brief study of Hospital formulary.

Drug Information Services - Sources of information on drug, diseases, treatment schedules; procurement of informations including

computer services. Drug profile, Cases on drug interaction and adverse reactions, Retrival of

information Documentation and prevention.


1. KhannaNK - Pharmacy Practical (CBS NT)

2. Cooper & Gunn - Dispersing for Pharmacy Students (CBS)

3. Nanda- Khar - Practical Dispensing Pharmacy (CBS)

4. N.K. Jain - Pharmaceutical Artimatic (CBS)

5. Jain & Sharma - TB of Professional Pharmacy (Vallabh)

6. Parmar NS - Health Edu & Community Pharmacy (CBS)

7. RM Mehta - Dispersing Pharmacy (Vallabh)

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: 3

rd Branch: B. Pharm

Subject: Pharmaceutics- Pharmaceutical Chemistry - IV (Organic – II) Code: 341313(41)




Heterocyclic Compounds:

Nomenclature, structure and reaction of Imidazole, Indole, Pyrrole, Furan,

Pyrimidine, Quinoline and Isoquinoline

Chemistry of: Lipids, Carbohydrates, Proteins and Nucleic acids.

Catalytic hydrogenation and dehydrogenation, Metal hydride reduction, Reduction with hydride and

its derivatives. Oxidation with peroxy acids. Electrolytic reaction. Sigmatropic reaction.

Selected reaction and mechanism of synthetic importance:

Mannich reaction, Beckmann reaction, Fitting reaction, Michael addition, Di alder

reaction, Witting rearrangement.

Polymer: Polymers and Polymerization and their importance in pharmacy

Nucleophillic aromatic substitutions, Electrophilic aromatic substitutions. Organic reagents used in

drug synthesis.


1. Morrison & Boyd - Organic Chemistry (TMH)

2. Morrison & Boyd - Problems in Organic Chemistry (TMH)

3. Harkishan Singh - Org. Pharma Chemistry (Vollabh)

4. R.K. Bansal - A TB of org Chemistry (New Age)

5. P.S. Kalsi - Stereo Chemistry - conformation &

Mechanism (New Age)

6. AK Srivastava - Organic Chemistry made Simple (New Age)

7. R K Bansal - Org Chemistry - Problem & Solution (New Age)

8. Bansal & Bansal - Org Chemistry - Problems & Solution (New Age)

9. PS Kalsi - Organic Reaction & their Mechanism (New Age)

10. Mukhargee/Singh/Kapoor - Org. chemistry Vol. I +II+III (New Age)

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: 3rd

Branch: B. Pharm

Subject: Anatomy, Physiology and Health Education - II Code: 341314(41)




Digestive System - Gross anatomy of the gastrointestinal tract, Functions of its different parts including

those of liver, pancreas and gall bladder, various gastrointestinal secretions and their role in

the absorption and digestion of food. Disorders of digestive system.

Respiratory System - Anatomy of respiratory organs, Functions of respiration, Mechanism and regulation of

respiration, Respiratory volumes and vital capacity.

Central Nervous System -

Function of different parts of brain and spinal cord, Neurohumoral transmission in the central

nervous system, Reflex action, Electroencephalogram, Specialized functions of the brain,

cranial nerves and their functions.

Autonomic Nervous System - Physiology and functions of the autonomic nervous system. Mechanism of neurohumoral

transmission in the A.N.S.

Urinary System - Various parts, Structures and functions of the Kidney and Urinary tract. Physiology of urine

formation and acid-base balance. Diseases of urinary system.

Reproductive System - Male and female reproductive systems and their hormones, Physiology of menstruation,

coitus and fertilization, Sex differentiation, spermatogenesis and oogenesis, Pregnancy - its

maintenance an parturition.

Endocrine System -

Basic anatomy and physiology of the Pituitary, Thyroid, Parathyroid, Adrenals, Pancreas,

Testis and Ovary, their hormones and functions.

Sense Organs - Basic anatomy and physiology of the of the eye (vision), ear (hearing) taste buds, nose

(smell) and skin (superficial receptors).

Health Education - Brief outline of communicable diseases, Their causative agents, Mode of transmission and

Prevention - Chicken pox, Measles, Influenza, Diphtheria, Whooping, cough, Tuberculosis,

Poliomyelitis, Hepatitis, Cholera, Typhoid, Food poisoning, Helminthiasis, Malaria,

Filariasis, Rabies, Trachoma, Tetanus, Syphilis, Gonorrhoea and AIDS.


1. CC. Chattergee - Human Physilolgy (Vol I+II) Central Scientific Boon co.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: 3rd

Branch: B. Pharm

Subject: Pharmacognosy - II Code: 341315(41)




Systematic pharmacognostic study of drug like:

Liquorice, Ginseng, Dioscorea, Sarasaparilla, Senega, Digitalis, Squill, Rhubarb, Cascara,

Aloe, Senna, Psorelea, Gentian, Saffron, Chirata, Quassia. Dill Fennel, Caraway, Clove,

Cinnamon, Nutmeg, Musk, Palmarosa, Gaultheria, Valerian.

Glycosides and Volatile oils:

General methods of classification, isolation, chemical properties and uses.

Biological sources, preparation, identification tests and uses of enzymes:

Diastase, Papain, Pepsin, Trypsin pancreatin. Plant bitters and sweetners.

Studies of traditional drugs like: Amla, Kantkari, Satavari, Guduchi, Giloya, Punarnava, Chitrak, Apamarg, Gokhru,

Shankhpushpi, Adusa, Arjuna, Ashoka, Brahmi, Methi, Lasun, Guggula, Nagarmotha, Neem,

Shilajit.

The holistic concept of drug administration in Ayurvedic and Traditional system of medicine.

Introduction to preparations of: Asava, Arishta, Tailas, Churnas, Lepas, Lehyas and Bhasmas and their evaluation

schemes.


1. Shah/Qadry – Parmacogonosy (B S Sahah, Ahmedabad)

2. T E Wallis – TB of Pharmacognosy (CBS New Delhi)

3. Trease/Evans – Pharmacognosy (Jay Perl, ND)

4. Kokate – Purohit – Pharmacognosy (Nirali/Pragati)

5. Handa-Kapoor – Pharmacognosy (Vallabh, ND)

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: 3rd

Branch: B. Pharm

Subject: Pharmaceutics- III (Pharmaceutical Engineering-I) Practical Practical Code:

341321(41)



Exp.1 - Study of psychometric charts.

Exp.2 - Measurement of pressure by using manometer.

Exp.3 - Measurement of Reynold’s number.

Exp.4 - Study of different types of valves.

Exp.5 - Measurement of humidity.

Exp.6 - Measurement of corrosion.

Exp.7 - Study of different types of conveyers.

Exp.8 - Determination of Radiation Constant.

Exp.9 - Study of the various elements of Computer Aided Manufacturing.

Exp.10 - Measurement of flow of fluid and their pressure.

Exp.11 - Study of various types of pumps.

Exp.12 - Determination of Overall Heat Transfer Coefficient


1. Brown. C.G., et el., Unit Operation, Asia Publishing House Mumbai.

2. K. Sambhamurty, Pharmaceutical Engineering.

3. Caretr. S. J., Cooper, and Gunn’s, Tutorial Pharmacy, CBS Publisher, New

Delhi.

4. Perry’s Chemical Engineer’s hand Book.

5. Bentley’s Text Book of Pharmaceutics, ELBS London.

5. C.V.S. Subrahmanyam, Pharmaceutical Engineering Principle & Practice,

Vallabh Prakashan, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Pharmaceutics- IV (Dispensing And Community Pharmacy) Practical Code: 341322(41)

Practical Total Practical Periods: 3


Exp.1 - To prepare & submit Emulsions.

Exp.2 - To prepare & submit Suspensions.

Exp.3 - To prepare & supply sodium chloride solution.

Exp.4 - To prepare & supply aqueous iodine solution.

Exp.5 - To prepare & supply strong ammonium acetate solution.

Exp.6 - To prepare & supply a carminative mixture.

Exp.7 - To prepare & supply an expectorant mixture.

Exp.8 - To prepare & supply a diuretic mixture.

Exp.9 - To prepare & supply a mixture containing diffusible solid.

Exp.10 - To prepare & supply calamine lotion.

Exp.11 - To prepare & supply salicylic acid & mercuric chloride lotion.

Exp.12 - To prepare & supply camphor liniments.

Exp.13 - To prepare & supply soap liniments.

Exp.14 - To prepare & submit dusting powders for antiseptic.

Exp.15 - To prepare & submit compound powder used as suspending agent.

Exp.16 - To prepare & submit tooth powders (Dentifrices).

Exp.17 - To prepare & supply capsules of acetyl salicylic acid.

Exp.18 - To prepare granules for tablets of compound sodium bicarbonate.

Exp.19 - To prepare & submit emulsifying ointments.

Exp.20 - To prepare & supply cold cream.

Exp.21 - To prepare & supply toothpaste.

Exp.22 - To prepare & submit boric acid suppositories.


1. Caretr. S. J., Cooper, and Gunn’s, Dispensing Pharmacy, CBS Publisher, New

Delhi.

2. Gennaro, A.R. ed., Remington’s. The Science and Practice of Pharmacy,

3. The concise Pharmaceutical Dispensing: Jain & Sharma.

4. Dispensing of Medication: Hoover.

5. Dispensing Pharmacy: R.M. Mehta.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Pharmaceutical Chemistry - IV (Organic – II) Practical Practical Code: 341323(41)



Exp.1 - Identification test for organic compounds.

Exp.2 - Determination of physical constants of organic compound.

Exp.3 - Perform the detection of elements.

Exp.4 - Determine the solubility of organic compounds.

Exp.5 - Determine the melting & boiling point of the different compounds.

Exp.6 - Identification test for sulphonamides.

Exp.7 - Identification test for phenothiazines.

Exp.8 - Identification test for Amoxycilline.

Exp.9 - Preparation & submit Aspirin.

Exp.10 - Preparation & submit Oxalic acid.

Exp.11 - Preparation & submit Benzoic acid.

Exp.12 - Determine Saponification value of the given oil or fat.

Exp.13 - Preparation & submit Benzamide.

Exp.14 - Perform the estimation of glucose.

Exp.15 - Perform the estimation of protein.

Exp.16 - Determine the strength of the given glycerine.


1. Organic Chemistry Vol.1 & Vol.2, I.L. Finar.

2. Organic Chemistry, Morrison & Boyd, Prentice hall Pvt. Ltd. New Delhi.

3. Organic Chemistry, Bahl & Bahl.

4. An Introduction to Heterocyclic Compound: Acheson.

6. Bentley Driver’s Text Book of Pharmaceutical, A.H. Atherden.

7. Indian Pharmacopoeia.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Anatomy, Physiology and Health Education - II Practical Practical Code: 341324(41)



Exp.1 - Study of digestive system by the help of charts & models.

Exp.2 - Study of Respiratory system by the help of charts & models.

Exp.3 - Study of Central Nervous System by the help of charts & models.

Exp.4 - Study of Autonomic Nervous System by the help of charts & models.

Exp.5 - Study of Urinary System by the help of charts & models.

Exp.6 - Study of Reproductive System by the help of charts & models.

Exp.7 - Study of Endocrine System by the help of charts & models.

Exp.8 - Study of Sense Organs by the help of charts & models.

Exp.9 - Study of the Clinical Features, mode of transmission & prevention of

selected communicable diseases from the course contents.

Exp.10 - Microscopic studies of different tissues of various systems mentioned in the

course.

Exp.11 - Analysis of Normal& Abnormal urine.

Exp.12 - Estimation of Red Blood Cells count.

Exp.13 - Estimation of White Blood Cells count.

Exp.14 - Determination of Erythrocyte Sedimentation rate.

Exp.15 - To study the experiments on spirometer.


1. Textbook of Practical Physiology, Ranade, V.G., Pune,Vidyarthi

Gritha Prakashan, Pune.

2. Human Physiology, Subhash Shalya, CBS Publishers & Distributer.

3. Human Physiology, Vendor, A.J. Sherman J. H. & Luciano.D.S. Tata

McGraw Hill Publishing Co., New Delhi.

4. Illustrated physiology, McNaught , A.B. and Callender,R.Churchill

Livingstone.

5. Guyton, Textbook of Medical Physiology, A.C.Guyton, W.B.Saunders

Company, 1995

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI Semester: 3

rd Branch: B. Pharm

Subject: Pharmacognosy - II Practical Practical Code: 341325(41)



Exp.1 - Study the Macroscopic & Microscopic Characters of Liquorice.

Exp.2 - Study the Macroscopic & Microscopic Characters of Digitalis.

Exp.3 - Study the Macroscopic & Microscopic Characters of Aloe

Exp.4 - Study the Macroscopic & Microscopic Characters of Senna

Exp.5 - Study the Macroscopic & Microscopic Characters of Chirata

Exp.6 - Study the Macroscopic & Microscopic Characters of Dill

Exp.7 - Study the Macroscopic & Microscopic Characters of Fennel

Exp.8 - Study the Macroscopic & Microscopic Characters of Clove.

Exp.9 - Study the Macroscopic & Microscopic Characters of Cinnamon.

Exp.10 - Study the Macroscopic & Microscopic Characters of Caraway.

Exp.11 - Study the Macroscopic & Microscopic Characters of Gokhru.

Exp.12 - Study the Macroscopic & Microscopic Characters of Arjuna

Exp.13 - Study the Macroscopic & Microscopic Characters of Ashoka.

Exp.14 - Study the Macroscopic & Microscopic Characters of Neem.

Exp.15 - Extraction of volatile oils from given drugs.

Exp.16 - Perform the identification tests of glycosides.


1. Evans, W.C., Trease and Evans Pharmacognosy, ELBS/Balliere London.

2. Kokate, C.K.,Pruhit ,A.P., Gokhle,S.B., Pharmacognosy, 5th

ed., Nirali

Prakashan,Pune.

3. Wallis, T.E., Textbook of Pharmacognacy, CBS Publications,New Delhi.

4. Shah, C.S., Quadry, J.S. Textbook of Pharmacognacy, B.S.,Shahprakashan,

Ahmedabad.

5. Kokate, C.K., Practical Pharmacognacy, Vallabh Prakashan, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY, BHILAI Course of Study and Scheme of Examination

Bachelor of Pharmacy IV-Semester


Minimum Pass Marks: Duration of Theory Papers: 3 Hours. (A) Theory and Sessional (combined): 50 Percent

(B) Practical and Sessional (combined): 50 Percent

Periods Per Week

Scheme of Exam Theory / Practical

Credits L+(T+P)/2

S.No. Board of

Study

Subject Code (New)

Nomenclature and Name of the Subject

L T P ESE CT TA Total Mark

s

1 Pharmacy 341411(41) Pharmaceutics - V (Pharmaceutical Engineering – II) 4 1 0 70 20 10 100 5

2 Pharmacy 341412(41) Pharmaceutics –VI (Dosage Form Design) 4 1 0 70 20 10 100 5

3 Pharmacy 341413(41) Pharmaceutical Analysis - I 4 1 0 70 20 10 100 5 4 Pharmacy 341414(41) Pharmaceutical Biotechnology 4 1 0 70 20 10 100 5 5 Pharmacy 341415(41) Pharmaceutical Microbiology 4 1 0 70 20 10 100 5 6 Pharmacy 341421(41) Pharmaceutics –V (Pharmaceutical

Engineering - II) Practical 0 0 3 60 - 40 100 2

7 Pharmacy 341422(41) Pharmaceutics – VI ( Dosage Form Design) Practical 0 0 3 60 - 40 100 2

8 Pharmacy 341423(41) Pharmaceutical Analysis -I Practical 0 0 3 60 - 40 100 2

9 Pharmacy 341424(41) Pharmaceutical Biotechnology Practical 0 0 3 60 - 40 100 2

10 Pharmacy 341425(41) Pharmaceutical Microbiology Practical 0 0 3 60 - 40 100 2

Total 20 5 15 650 100 250 1000 35

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: 4th Branch: B. Pharm

Subject: Pharmaceutics- V (Pharmaceutical Engineering-II) Code: 341411(41) Total Marks in End Semester Exam: 70 Minimum no. of class tests to be conducted: 2

Size Reduction and Size Separation -

Definition objectives and significance of size reduction, Factors affecting size reduction, Standard of powders, Sieves and their usage in grading of powders, Laws governing energy and power requirements of a mill, Classification of size reduction machines, Study of various types of mill including ball mill, hammer mill, fluid energy mill etc. Mathematical problems.

Evaporation - Basic concepts, Factors affecting evaporation, Types of evaporators, Study of short tube evaporators, Forced circulation evaporators and Film evaporators, Single and multiple effect evaporation, Evaporation under reduced pressure, Evaporation capacity, Heat and material balance, Scale formation, Foam and entrainment, Mathematical problems.

Distillation - General theory applied to binary mixtures, Boiling point and equilibrium diagrams, Raout’s Law and Henry’s Law, Constant boiling mixtures. Simple, steam and Equilibrium distillations. Rectification, Constructions of rectifying columns. Analysis of rectifying column : McCabe Thiel method and Lewis Sorel method for calculation of number of theoretical plates, Azeotropic and extractive distillations.

Drying - Introduction, Theory of drying Rate of drying curves, Classification of dryers, Study of dryers used in pharmaceutical industries, Special drying methods, Mathematical problems.

Extraction - Principles of solid-liquid and liquid- liquid extraction, Theories of extraction of drugs, Diffusion battery, Continuous counter-current extraction system.

Crystallization - Importance of crystal purity, size, shape, geometry, habit, forms and types. Solubility curves and calculation of yields, Mier’s supersaturation theory and its limitations, Nucleation and crystal growth, Classification of crystallizers, Principles underlying the design and operation of Tank, Swenson-walker, Krystal and Vacuum crystallizer. Crystallizer employed for producing large crystals, Caking of crystals and its prevention, Mathematical problems.

Mixing - Theory of mixing, Solid -solid, solid-liquid and liquid- liquid mixers used in pharmaceutical industries.

Theory of filtration, Factors affecting filtration, Filter media, Filter aids, Classification of filters, Industrial filters including Filter press, Rotary filter, Membrane filter etc. Mathematical problems. Principles of centrifugation, Industrial filters and centrifugation sedimenters.

Pilot Plant Scale Up Techniques - Concepts of pilot plant, scale up techniques in pharmaceutical industries.


Filtration and Centrifugation -

www.Pharmainfo.Net

www.Pharmainfo.Net



Total Marks in End Semester Exam: 70 Minimum no. of class tests to be conducted: 2 Preformulation studies:

Study of physical, chemical and pharmaceutical factors influencing drug formulation, stability and bioavailability.

Study of different types of formulation additives like – Diluents, Binders Disintegrators, Lubricants, Solvents, Co-solvents and Vehicles, Antioxidants, Preservatives, Suspending, Emulsifying, Coloring, Flavoring and Sweetening agents, Viscosity enhancers, Materials for Ointment; Cream and Suppository bases, Drug-excipient interactions and incompatibilities.

Polymers: Polymers and biodegradable polymers, Classification, Properties, Characterization and Evaluation, Mechanism of biodegradation in the body, Pharmaceutical applications of polymers.

Stability Studies: Stability testing protocols for various pharmaceutical dosage forms, Determination of expiry date (shelf life) and overage calculations, Stabilization of pharmaceutical formulations. Design, development and process validation methods for pharmaceutical operations involved in manufacturing of dosage formulations with special reference to solid and liquid dosage forms.

Performance evaluation methods : 1. In-vitro dissolution studies for solid dosage forms: Methods, Interpretation of

dissolution data. 2. Bioavailability studies and bioavailability testing: Protocols and Procedures. 3. In-vivo methods of evaluation, statistical treatment.

Standard operating process for different dosage formulations, Process optimization, New Product launch.

Reference/Recommended Books:

1. B M Mithal-TB of Pharma Formulation (Vallabh) 2. Jain/Sharma-TB of Professional Studies (Vallabh) 3. Banker-Modern Pharmaceutics (D &P Series) KMV 4. Cole GC- Pharma Production Facilities (f 99.00-CBS, No) 5. Hillery et al - Drup Delivery & Targettirs (l 35.00- CBS No) 6. Jain N K – Controlled & Novel Drup Delivery (CBS, No)

Subject: Pharmaceutics - VI (Dosage Form Design) Code: 341412(41) Total Theory Periods: 40 Total Tut. Periods: 1

www.Pharmainfo.Net

www.Pharmainfo.Net



Total Marks in End Semester Exam: 70 Minimum no. of class tests to be conducted: 2

Fundamentals, Significance of quantitative analysis in quality control, Different techniques of analysis.

Theoretical considerations and pharmaceutical applications; with special reference to Indian pharmacopoeia; of the following analytical techniques -

1) Acid-Base titrations.

2) Oxidation-Reduction titrations.

3) Precipititation titrations.

4) Gravimetric analysis.

5) Non-aqueous titrations.

6) Complexometric titrations.

7) Conductometry.

8) Potentiometry.

Miscellaneous methods of analysis like diazotisation titrations, Kjeldahl method of nitrogen estimation, Karl-fisher titrations. Reference/ Recommended Books: 1. P. Parimoo-Pharmaceutical Analysis (CBS) 2. Willard-Instrumental Methods of Analysis (CBS) 3. B K Sharma- Instrumental Methods of Analysis (Krishna-Meera) 4. Kasture/Gokhale-Pharma Analysis (pt I+II) Nirali/Prapa 5. Chatwal-Instr Methods of Analysis (Himalaya Pub.)

Subject: Pharmaceutical Analysis - I Code: 341413(41) Total Theory Periods: 40 Total Tut. Periods: 1

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI


Total Marks in End Semester Exam: 70 Minimum no. of class tests to be conducted: 2 Historical Development - Immunology and Immunological Preparations:

Principles, Antigens and antibodies, Antigen-antibody reactions and their applications, Immune system. Cellular humoral immunity, Immunological tolerance, Hypersensitivity, Immunological and diagnostic preparations: Methods of their preparation, standardization and storage.

Enzyme Immobilization - Techniques of Immobilization of enzymes, kinetics and factors affecting enzymes kinetics, Enzymes electrodes, Enzymes based sensors, Study of enzymes such as Hyaluronidase, Penicillinase, Strepto-kinase, Amylases, Proteases etc. Immobilization of bacteria and plant cells, Applications of Immobilization.

Genetic Recombination: Transformation, Conjugation, Transduction, Protoplast fusion, Gene cloning and their applications, Monoclonal antibodies and hybridoma technology, Recombinant DNA technology: Concepts, Methodology and Pharmaceutical applications. Study of drugs produced by biotechnology such as Activase, Humulin, Humatrope, Intron A, Monoclate, Orthoclone OKT3, Referon-A, Recombivax HB etc. Drug delivery systems in Gene therapy.

Microbiological Transformation - Introduction, Types of reactions mediated by microorganisms. Design of biotransformation processes, Selection of organisms, Biotransformation processes and its improvements with special reference to steroids.

Industrial Biotechnology - Historical development, Fermenter and its design, Control of different

parameters in fermentation process, Isolation of mutants, Use of mutagenic agents, Factors in influencing rate of mutation. Design of fermentation process, Fermentative, production of Alcohol, Acetic acid, Penicillin, Streptomycin, Riboflavin, Vitamin B12.

Reference/Recommended Books

1. R.S. Setty/GR Veena – Biotechnology I (New Age, New Delhi) 2. Setty/Sreekrishna – Biotechnology II (New Age, New Delhi) 3. S Mahesh– Biotechnology III (New Age, New Delhi) 4. Mahesh/Vedamurthy – Biotechnology IV (New Age, New Delhi) 5. M K Mahesh – Biotechnology V (New Age, New Delhi) 6. K Trehan-Biotechnology (New Age, New Delhi

Subject: Pharmaceutical Biotechnology Code: 341414(41) Total Theory Periods: 40 Total Tut. Periods: 1

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI


Total Marks in End Semester Exam: 70 Minimum no. of class tests to be conducted: 2

Introduction to the Microbiology -

Historical development, contribution of great scientists and scope of microbiology. Microbiological Taxonomy -

Classification of Bacteria and Viruses. Identification of Microbes -

Working of different types of microscopes, Electron microscopy, Stains and types of staining techniques. Structure and Morphology of bacteria and viruses. Nutritional requirements, Cultivation and Isolation of bacteria and viruses. Microbial genetics and variation.

Control of microbes by physical and chemical methods: Disinfection: Factors influencing disinfection, dynamics of disinfection, Disinfectants and antiseptics, and their evaluation.

a) Sterilization: Different methods, Validation of sterilization methods and equipments.

Sterility testing of pharmaceutical products: Infection and factors influencing infection, Immunity, Primary and Secondary defensive mechanisms of body, Microbial resistance, Interferon. Microbial assay of antibiotics and vitamins. Food spoilage and Preservation of food.

Sewage and Sewage Disposal - Industrial Sewage, Sewage treatment methods, BOD, COD etc.

Reference/Recommended Books:

1. N K Jain - Pharmaceutical Microbiology (Vallabh) 2. Shah-Shah – A TB of Pharma Micro (BS Shah) 3. K R Aneja – Expts in Microfiol & Biotech (New Age) 4. L E Casida – Indurtrial Microbiology (New Age) 5. Kale-Bhnsari – Microbiology (Himalaya Pub) 6. Singh/Dwivedi – Environmental Microbiol & Biotech (New Age)

Subject: Pharmaceutical Microbiology Code: 341415(41) Total Theory Periods: 40 Total Tut. Periods: 1

www.Pharmainfo.Net

www.Pharmainfo.Net



Total Practical Periods: 3 Total Marks in End Semester Exam: 60

Exp.1 - To illustrate principles of size reduction laws governing energy &

power requirements of size reduction.

Exp.2 - Determination rate of evaporation.

Exp.3 - Experiment based on steam, extractive & azeotropic distillation.

Exp.4 - Experiment to illustrate the influence of various parameter on the

rate of drying.

Exp.5 - Determination of rate of drying.

Exp.6 - Determination of heat transfer coefficient.

Exp.7 - Experiments based upon extraction.

Exp.8 - Experiments based on crystallization.

Reference / Recommend Books: 1. Brown. C.G., et el., Unit Operation, Asia Publishing House Mumbai. 2. K. Sambhamurty, Pharmaceutical Engineering. 3. Caretr. S. J., Cooper, and Gunn’s, Tutorial Pharmacy, CBS Publisher, New Delhi. 4. Perry’s Chemical Engineer’s hand Book. 5. Bentley’s Text Book of Pharmaceutics, ELBS London. 5. C.V.S. Subrahmanyam, Pharmaceutical Engineering Principle & Practice, Vallabh Prakashan, New Delhi.

Subject: Pharmaceutics- V (Pharmaceutical Engineering-II) Practical Practical Code: 341421(41)

www.Pharmainfo.Net

www.Pharmainfo.Net




Exp.1 - Estimation of bulk density, & percentage of carr’s index.

Exp.2 - To find out the angle of repose.

Exp.3 - To find out the particle size analysis.

Exp.4 - Drug excipients compatibility study.

Exp.5 - Stability testing –

a) Accelerated stability study.

b) Force degradation study.

Exp.6 - Moisture pick- up study.

Exp.7 - To find out the percentage of drug release with the help of

dissolution apparatus of some marketed pharmaceutical products.

Reference / Recommend Books: 1. Raemigton’s Pharmaceutical Sciences – Gennaro A.R., ed.,19th Edition,

Mack, Publishing Co.,Easton, P.A.1995. 2. Arisel, H.C., Introduction to Pharmaceutical dosage forums, K.M.

Verghese & Co.,Mumbai. 3. Aulton, M.E., Pharmaceutics – The Science of dosage form design, ELBS, London. 4. Mithal , B.M., Text Book of Pharmaceutical Formulations, Vallabh

Prakashan, New Delhi. 5. Lachman , L., Liberman, H.A. , Theory and practice of Industrial –

Pharmacy, Lea & Febiger Philadelphia, USA.

Subject: Pharmaceutics - VI (Dosage Form Design) Practical Practical Code: 341422(41)

www.Pharmainfo.Net

www.Pharmainfo.Net




Exp.1 - Calibration of Analytical balance. Exp.2 - To estimate the normality of unknown Kmno4 solution by the help of standard N/30 Ferrous Sulphate solution. Exp.3 - Practical Non Aqueous Titration –

a) Preparation & Standardization of Perchloric acid & Sodium/ Potassium/ Lithium Methoxide solution.

b) Estimation of some pharmacoepial products. Exp.4 - Complexometric Titration –

a) Prepration & standerization of EDTA solution. b) Some exercise to pharmacoepial assays By complexometric

titration. Exp.5 - Miscellaneous determination.

a) Karl – fischer titrations. b) Diazotisation titrations. c) Kjeldahl method of Nitrogen estimation.

Exp.6 - Exercise based on acid base titration in aqueous & non aqueous media. Exp.7 - Exercise based on oxidation reduction titration using

potentiometric techniques. Exp.8 - Determination of acid base dissociation constant & plotting titration curve using pH meter. Exp.9 - Exercise based on conductometric titration of some pharmaceutical products.


1. A Textbook of Pharmaceutical Analysis – Conors. 2. Pharmaceutical Analysis – L.G.Chatten. 3. Vogels “Text Book of Quantitative Inorganic Analysis.” 4. Backett and Stenlake “Practical Pharmaceutical Chemistry – Part-I.” 5. Dr.K.R.Mahadik, Dr.H.N.More.,Pharmaceutical analysis –I and II ,

Instrumental Methods. Nirali Prakashan ,Pune. 6. Ashutosh Kar,Pharmaceutical and Drug Analysis.

Subject: Pharmaceutical Analysis – I Practical Practical Code: 341423(41)

www.Pharmainfo.Net

www.Pharmainfo.Net




Exp.1 - Prepare & evaluate enzyme immobilized calcium alginate beads.

Exp.2 - To extract tyrosinase from potato and study the substrate specificity on different substrate. Exp.3 - Determine the enzyme kinetics of pepsin. Exp.4 - Enzyme immobilization with gelatin gel solution. Exp.5 - DNA isolation from onion. Exp.6 - Treat yogurt fermentation with lactobacillus bacteria. Exp.7 - Perform isolation of RNA from yeast cell. Exp.8 - A, B, O Blood group typing of own blood IgM mediated

agglutination reaction. Exp.9 - Estimate total protein content in alginate beads by biurate

reagents. Exp.10 - Isolate enzyme urease & determine its practical yields. Exp.11 - Batch submerged Fermentation of broken’s yeast. Exp.12 - Isolation of lecithin from egg yolk. Exp.13 - Isolation of glutein from wheat flour. Exp.14 - Separation of Amino acids by using TLC. Exp.15 - Preparation of alcohol by using fermentation process.


1. Carter, S.J., Cooper and Gunn’s Tutorial Pharmacy, CBS Publishers,Delhi.

2. Rawlins, E.A., Bentley’s Text Book of Pharmaceutics, ELBS Balliere tindall.

3. Hugo, W.B. and Russell, A.D., Pharmaceutical microbiology, Blackwell Scientific Pubication, Oxford. 4. Wiserman, A.ed., Handbook of enzyme biotechnology, Ellis Harwood

Ltd., Chichester 5. Cassida Jr.,L.E., Industrial Microbiology, Wiley , eastern Limited, New

Delhi. 6. Donald M.Weir, John Stewart, Immunology, Churchill Livingstone,

London.

Subject: Pharmaceutical Biotechnology Practical Practical Code: 341424(41)


www.Pharmainfo.Net

www.Pharmainfo.Net




Exp.1 - Study of different types of Microscopes.

Exp.2 - Study of Hot air oven.

Exp.3 - Study of Auto clave.

Exp.4 - Study of Incubator.

Exp.5 - Identification of microorganism by different method.

Exp.6 - To prepare & sterilize Nutrient Agar.

Exp.7 - To prepare & sterliseThioglycolate media.

Exp.8 - Microbial assay’s of antibiotics.

Exp.9 - Microbial assays of vitamins.

Exp.10 - To study the lactose fermenting bacteria from milk sample using

differential plating.

Exp.11 - Testing the sterility of pharmaceutical products.(Creams & ointments)

Exp.12 - To perform sterility test for aqueous solution & suspension.

Exp.13 - To perform sterility test for water for injection.

Exp.14 - To study the effect of pH of the culture media on the growth of microbes.

Exp.15 - To study the effects of osmotic pressure on growth of microbes.


1. Carter, S.J.Cooper and Gunns, Tutorial Pharmacy, 6th ed. CBS Publishers, Delhi,1986.

2. Carter, S.J.Cooper and Gunns, Dispensing for Pharmaceutical Students, CBS Publishers,New Delhi,1987.

3. Pharmaceutical Microbiology ,N.K.Jain. 4. Hugo,W.B. and Russell A.D., Pharmaceutical Microbiology, Blackwell

Scientific Publication Oxford.

5. Ralins, E.A. , Bentley’s Text Book of Pharmaceutics 8th ed., Balliere Tindall,1977

Subject: Pharmaceutical Microbiology Practical Practical Code: 341425(41)


www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Scheme of Teaching and Examination

Bachelor of Pharmacy

V - Semester

Minimum Pass Marks (A) Theory and Sessional (Combined) : 50 Percent Duration of Theory Papers ; 3 Hour (B) Practical and Sessional (combined): 50 Percent

Periods Per Week


S.No Board of

Study

Subject Code (New)


L T P ESE CT TA Total Marks

Credits L+(T+P)/2

1 Pharmacy 341511(41) Pharmaceutics – VII (Cosmetic Technology)

4 1 - 70 20 10 100 5

2 Pharmacy 341512(41) Pharmaceutical Chemistry V (Biochemistry)

4 1 - 70 20 10 100 5

3 Pharmacy 341513(41) Pharmaceutical Chemistry VI (Medicinal Chemistry – I)

4 1 - 70 20 10 100 5

4 Pharmacy 341514(41) Pharmacognosy – III 4 1 - 70 20 10 100 5

5 Pharmacy 341515(41) Pharmacology – I 4 1 - 70 20 10 100 5

6 Pharmacy 341521(41) Pharmaceutics – VII (Cosmetic Technology) Lab

- - 3 60 - 40 100 2

7 Pharmacy 341522(41) Pharmaceutical Chemistry V (Biochemistry) Lab

- - 3 60 - 40 100 2

8 Pharmacy 341523(41) Pharmaceutical Chemistry VI (Medicinal Chemistry – I) Lab

- - 3 60 - 40 100 2

9 Pharmacy 341524(41) Pharmacognosy – III Lab - - 3 60 - 40 100 2

10 Pharmacy 341525(41) Pharmacology – I Lab - - 3 60 - 40 100 2

Total 20 5 15 650 100 250 1000 35

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutics – VII (Cosmetic Technology ) Code: 341511 (41) Total Theory Periods: 50 Total Tutorial Periods: 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Fundamentals of cosmetic sciences. Structure and function of skin and hair. Formulation considerations, preparation, packaging and evaluation of the following categories of cosmetics:

1. Face Preparations: Face powder, Compact powder, Talcum powder, Face packs and Masks. 2. Skin Preparations: Skin creams, Anti-wrinkle preparations, Barrier materials, Protective creams

and gels, Vanishing creams, Cold creams, Cleanising creams, Emollient, Anti-perspirant / deodorant, Moisturising and foudation formulations. Bleaching creams, Night and Massage cream, Hand cream, Protective skin tonics, Skin moisturisers, Sunscreen, Suntan, and anti- sun burn preparations.

3. Shaving preparations: Lather shaving stick, Lather shaving cream, Shaving foams, Shaving

gels, Pre- and After shave lotions. 4. Shampoo and Bath preparations: Clear liquid shampoo, Aerosol shampoo, dry shampoo,

Acid-balanced shampoo, Egg shampoo, Bath oils, Foam baths.

5. Hair Preparations: Hair tonics, Hair conditioners, Hair lotions, Hair sprays, Hair dressings, Hair setting lotions and creams, Hair dyes, Bleaches, Hair waiving, Hair straightners and Hair strengthners.

6. Dentrifice: Tooth powders, Tooth pastes, Solid dentrifice, Tooth brush and Denture cleansers.

7. Foot Preparations: Foot powders, Foot sprays, Foot creams, Corn preparations and Athelete’s

foot preparation.

8. Manicure Preparations: Nail polish, Nail lacquer and Nail bleach.

9. Herbal Cosmetics: Cosmetics containing Aloe, Babul, Brahmi, Chandan, Cucumber, Haldi, Jatamansi, Khus, Mehandi, Neem, Reetha, Shikakai, Tulsi, Arnica, Amla, Bhringraj and Volatile oils.

10. Cosmetic for babies. 11. Colored make-up preparations: Lipsticks, Rouge, Mascara, Eye make-up, Eye-liner, Eyebrow

pencils.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry –V ( Biochemistry ) Code: 341512 (41) Total Theory Periods: 50 Total Tutorial Periods: 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Biochemical organization of the cell and transport processes across cell membrane. The concept of free energy, determination of charges in free energy system from equilibrium constant and reduction potential, bioenergetics, production of ATP and its biological significance. Enzymes: Nomenclature, Kinetics and its Mechanism of action, Mechanism of Inhibition, Isoenzymes, enzymes in technical diagnosis. Co-enzymes: Metals as coenzymes and their significance and Vitamins as coenzymes and their significance. Carbohydrate Metabolism: Conversion of Polysaccharide to Glucose 1-Phosphate, Glycolysis and Fermentation and their regulation, Gluconeogenesis and Glycogenolysis, metabolism of galactose and galactosemia, role of sugar nucleotide in biosynthesis, pentosephosphate pathway. The Citric acid cycle: The significance, reaction and energetics of cycle, amphibolic role of cycle, Glyoxalic Acid Cycle. Lipid Metabolism: Oxidation of fatty acids, Beta Oxidation and energetic, alpha oxidation, omega oxidation, Biosynthesis of Ketone bodies and their utilisation, Biosynthesis of saturated and unsaturated fatty acids and eicosanoids, phospholipids, sphingolipids. Biological oxidation:

Redox Potential, enzymes and co-enzymes involved in oxidation-reduction and its control. The respiratory chain, its role in energy capture and its control, energetic of oxidative phosphorylation, inhibitors of respiratory chain and oxidative phosphyrlation, mechanism of oxidative phosphorylation. Nitrogen & Sulphur Cycle: Nitrogen fixation, ammonia assimilation, sulphur activation, sulphate reduction, incorporation of sulphur in organic compounds, release of sulphur from organic compounds Metabolism of Ammonia and Nitrogen Containing monomers: Nitrogen balance, biosynthesis of amino acids, catabolism of amino acids, conversion of amino acids to specialized products, assimilation of ammonia, urea cycle, metabolic disorders of urea cycle, metabolism biosynthesis, formation of bile pigment, hyperbilirubinemia, purine biosynthesis, purine nucleotide interconversion, pyrimidine biosynthesis, and formation of deoxyribonucleotides. Biosynthesis of nucleic Acids: Brief introduction to genetic organisation, organisation of mammalian genome, alteration and rearrangement of genetic material, biosynthesis of DNA and its replication, mutation,physical and chemical mutagenesis/ carcinogenesis, DNA repair mechanism, biosynthesis of RNA. Genetic code and Protein synthesis:Genetic code, Components of protein synthesis and inhibition of protein synthesis. Brief account of genetic engineering and polymerase chain reactions. Regulation of gene expression.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry –VI (Medicinal Chemistry – I) Code: 341513 (41) Total Theory Periods: 50 Total Tutorial Periods: 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Introduction: Basic principles of medicinal chemistry, physicochemical and stearic aspects (optimal, geometric and bioisosterism) of drug molecules and biological actions.

Drug Metabolism and Prodrug Concept Drug receptor interaction including transduction mechanism and G proteins. The synthesis of the selected drugs, classification and mode of action, uses, SAR including physicochemical and stearic aspects of the following category of drugs:

(A) Drugs acting at synaptic and narrow effector junction sites

1. Cholinergics and Anticholinesterases.

2. Adrenergic hormones and Drugs;

3. Neuromuscular Blocking Agent.

4. Local Anaesthetics.

(B) Autocoids

1. Antihistamines.

2. Euiconosoids.

3. Non-steroidal anti-inflammatory agents, analgesic antipuretics.

(C) Vitamins: Vitamin A, Thiamine, Riboflavin, Folic Acid, Niacin, Panthotenic Acid, Pyridoxine, Cyanocobalamine, Vitamin C, Vitamin D, Vitamin E, Vitamin K.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmacognosy –III Code: 341514 (41) Total Theory Periods: 50 Total Tutorial Period – 12 Total Marks in End Semester Exam: 70


General techniques of biosynthetic studies and basic metabolic pathways. Introduction to biosynthesis of secondary metabolites of pharmaceutical importance. A brief introduction of chemical nature of phytoconstituents.

Radio – tracer techniques and utilization in biogenetic studies.

Phytochemical Screening: Preparation of extracts and different methods used for screening extracts for the presence of alkaloids, saponins, steroidal compounds, flavanoids, anthraquinones, phenolics, amino acids, etc. Concepts of stereoisomerisms taking examples of natural products. Nature, distribution, classification, general methods of isolation and properties of alkaloids and terpenoids. Chemistry, biogenesis and pharmacological activity of atropine, reserpine, ephedrine, ergometrine, quinine, morphine, digitoxin, sennosides, diosgenin, sarsapogenin, menthol, citral, taxol, rutin and artemisine. Systematic pharmacognostical study of drugs like; Tobacco, Belladona, Hyoscyamus, Datura, Coca, Withania, Cinchona, Ipecac, Opium, Ergot, Rauwolfia, Vinca, Nuxvomica, Physostigma, Pilocarpus, Veretrum, Kurchi, Ephedra, Solanam, Tea, Colchicum, etc.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmacology -I Code: 341515 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70

Minimum number of class tests to be conducted: 2 General Pharmacology

a. Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, mechanism of action, combined effects of drugs, factors modifying drug action, tolerance and dependence, pharmacogenetics. b. Absorption, distribution and excretion of drugs, principle of basic and clinical pharmacokinetics adverse drug reactions and treatment of poisoning, ADME drug interaction, bioassay of drugs and biological standardization, discovery and development of new drugs.

Pharmacology of Peripheral Nervous System:

a. Neurohumoral transmission (autonomous and somatic)

b. Parasympathomimetic, parasympatholytic, sympathomimetics, adrenergic receptors and neuron

blocking agents.

c. Neuromuscular blocking agents

d. Local anaesthetic agents

Autocoids

a. Histamine, 5- HT and their antagonists.

b. Prostaglandins, Thromboxanes and Leukotrienes.

c. Pentagastrins, Cholecystokinin and Angiotensin.

Analgesic, Antipyretic, Anti-inflammatory and Anti-Gout Drugs:

Drugs acting on Respiratory System and Pathophysiology of respiratory system:

a. Anti-asthmatic drugs including bronchodilators b. Anti-tussives and expectorants c. Respiratory stimulants

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutics – VII (Cosmetic Technology) Lab Code: 341521 (41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60

Experiments to be performed:

Exp.1 - To study the structure & functions of skin & hair.

Exp.2 - Prepare & submit talcum powder.

Exp.3 - Prepare & submit face powder.

Exp.4 - Prepare & submit vanishing cream.

Exp.5 - Prepare & submit moisturizing cream.

Exp.6 - Prepare & submit bleaching cream.

Exp.7 - Prepare & submit anti sun burn cream.

Exp.8 - Prepare & submit lather shaving cream.

Exp.9 - Prepare & submit after shave lotion.

Exp.10 - Prepare & submit hair shampoo.

Exp.11 - Prepare & submit hair creams.

Exp.12 - Prepare & submit tooth powder & tooth paste.

Exp.13 - Prepare & submit athelete’s foot prepration.

Exp.14 - Prepare & submit nail polish.

Exp.15 - Prepare & submit herbal cosmetics containing Aloe, Haldi, Mehndi

& Amla.


1. Harry’s cosmeticology

2. Sagarin & Balsam, M.S. conmetic Science and Technology, Vol. 1-3, Johjn Wiley & Sons, NY, USA

3. Mac Chesney, J.C. Packaging of Cosmetic and Toiletries, Newsness Butterworth, London.

4. Jellinek, J.S., Formulation and Functions of Cosmetics, John willey & sons, New York.

5. Thomssen, SG., Modern Cosmetics, Universal Publishing corporation, Bombay.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry –V (Biochemistry) Lab Code: 341522 (41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60

Experiments to be performed

Exp.1 - Qualitative & Quantitative chemical examination of urine, blood & faeces. Exp.2 - Food analysis – analysis of milk, butter, flour, honey and starch. Exp.3 - Qualitative test for protein. Exp.4 - Qualitative test for carbohydrate. Exp.5 - To determine the Km value for the Beta -amylase. Exp.6 - Estimation of Vitamin C by potassium iodate methode. Exp.7 - To perform the test for normal & abnormal constituents present in given sample. Exp.8 - To dtermine titrable acidity of ammonia in urine. Exp.9 - Estimation of protein by Biuret method. Exp.10 - Quantitative estimation of amino acids. Exp.11 - Separation of lipids by thin layer chromatography. Exp.12 - Separation of Amino acids by two dimensional paper chromatography & gel electrophoresis. Exp.13 - Separation of serum proteins by electrophoresis on cellulose acetate. Exp.14 - Quantitative estimation of reducing sugar (Glucose) in urine. Exp.15 - Isolation & determination of DNA & RNA. Exp.16 - Perform the liver function tests.


1. Principles of Biochemistry – White, Smith & Handler Latest edition, Tata McGraw Hill

2. Principles of Biochemistry by A.L. Lehninger, Worth Publishers, Inc Latest Edition.

3. Harpers Biochemistry – Prentice Hall International Inc. Latest Edition.

4. Text Book of Biochemistry by West & Todd.

5. Fundamentals of Biochemistry by Dr. A.C. Deb, Sixth edition, Reprint – 1997, New Central Book Agency (P) Ltd., Calcutta.

6. Lehninger, A.L., Principles of Biochemistry, CBS Publishers and Distributors.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry –VI (Medicinal Chemistry-I) Lab Code: 341523 (41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60

Experiments to be Performed

Exp.1 - To prepare phthelinide from phthalic anhydride.

Exp.2 - Prepare & submit pthalide from pthalimide.

Exp.3 - Prepare & submit flurocin from phathalic anhydride.

Exp.4 - Prepare & submit benzoyl chloride of benzoin.

Exp.5 - Prepare & submit benzilic acid from benzoil.

Exp.6 - Establishing the pharmacopoeial standards of the drugs synthesized.


1. Foye, W.C. Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia.

2. Wolff, M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New York.

3. Hansch, C., Comprehensive Medicinal Chemistry, Pergarnon Press, Oxford.

4. Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Test Book of Organic, Medicinal and Pharmaceutical Chemistry, J.Lippincott Co., Philadelphia

5. Nogrady, T., Medicinal Chemistry-A Biochemical Approach, Oxford University Press, New York, Oxford.

6. Furnis, B.S. (ed.), Vogel’s Text Book of Practical Organic Chemistry, 4th edn. ELBS,

1980. 7. Kadam & Mahadik’s A Test book of Medicinal Chemistry.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND TECHNICAL UNIVERSITY, BHILAI Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmacognosy –III Lab Code: 341524 (41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60


Exp.1 - To study the Macroscopic & Microscopic character of Datura.

Exp.2 - To study the Macroscopic & Microscopic character of Withania.

Exp.3 - To study the Macroscopic & Microscopic character of Cinchona.

Exp.4 - To study the Macroscopic & Microscopic character of Rauwolfia.

Exp.5 - To study the Macroscopic & Microscopic character of Vinca.

Exp.6 - To study the Macroscopic & Microscopic character of Nuxvomica.

Exp.7 - To study the Macroscopic & Microscopic character of Kurchi.

Exp.8 - To study the Macroscopic & Microscopic character of Ephedra.

Exp.9 - To study the Macroscopic & Microscopic character of Tea.

Exp.10 - To study the Macroscopic & Microscopic character of Ipecac.

Exp.11 - Isolate various types of alkaloids from the drugs from course contents.

Exp.12 - Isolate various type of saponines from the drug’s from course contents.

Exp.13 - Isolate various of flavonoids from the drugs from course contents.

Exp.14 - Chemical evaluation of powder drugs.


1. Trease, G.E. and Evans, W.C., Pharmacognosy, Bailliere Tindall, Eastbourne, U.K.

2. Tayler, V.C., Brady, L.R. and Robers, J.E., Pharmacognosy, Lea and febiger, Philadelphia

3. Shah, C.S. and Quar\dry, J.S. A text book of Pharmacognosy, B.S. Shah Publishers, Ahmedabad.

4. Kokate, C.K., Purohit, A.P., and Gokhale, S.B., Pharmacognosy, Nirali Prakashan, Pune.

5. Wallis, T.E. Text Book of Pharmacognosy, Jand A Churchill Limited, London.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. V Sem. Branch: Pharmacy Subject: Pharmacology -I Lab Code: 341525(41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60


Exp.1 - Study the student organ bath.

Exp.2 - Draw & study the different types of recording levers

Exp.3 - Study the different type of recordings procedures.

Exp.4 - Preparation of standard drug solution of the experiment.

Exp.5 - Preparation of physiological salt solution for the experiment.

Exp.6 - Study of the different types of experimental animals.

Exp.7 - Draw & study to the animal house equipments.

Exp.8 - Study the techniques of holding the animals.

Exp.9 - Study the mode of administration of drugs of the animals.

Exp.10 - Study of common laboratory anaesthetics used in animal study.

Exp.11 - Study the effect of acetylcholine and adrenaline on frogs heart.

Exp.12 - Effect of acetylcolin on rectus abdominus muscle of frog.

Exp.13 - Effect of local anaesthetics on rabbit cornea.

Exp.14 - Study the effect of convulsants and anti convulsants in mice.

Exp.15 - To record C.R.C of Histamin and guinea pig ileum preparations.


1. Hardmen, J.G., Limbired, L.E. Molinoss, P.B., Ruddon, R.W. and Gil, A.G., Goodman and Gillman’s The Pharmacological basis of Therapeutics, Pergamon Press.

2. Satoskar, R.S. and Bhandarkar, S.D., Pharmacology and Pharmacotherapeutics. 3. Tripathis, K.D., Essentials of Medeical Pharmcology.

4. Rang, M.P. Dale, M.M. and Riter, J.M, Pharmacology, Churchil Livingstone.

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University, Bhilai

Scheme of Teaching and Examination Bachelor of Pharmacy

VI- Semester

Minimum Pass Marks (A) Theory and Sessional (Combined) : 50 Percent Duration of Theory Papers ; 3 Hour (B) Practical and Sessional (combined): 50 Percent

Periods Per Week

Scheme of Exam Theory /Practical S.N

o. Board of

Study

Subject Code (New)


L T P ESE CT TA Total Mark

s

CreditsL+(T+P)/

2

1 Pharmacy 341611 (41) Pharmaceutical Industrial Management 4 1 - 70 20 10 100 5

2 Pharmacy 341612 (41) Pharmaceutical Analysis II 4 1 - 70 20 10 100 5

3 Pharmacy 341613 (41) Pharmaceutical Chemistry VII (Medicinal Chemistry – II)

4 1 - 70 20 10 100 5

4 Pharmacy 341614 (41) Pharmacology – II 4 1 - 70 20 10 100 5

5 Pharmacy 341615 (41) Pharmaceutics – VIII 3 1 - 70 20 10 100 4

6 Pharmacy 341621 (41) Pharmaceutical Chemistry VII (Medicinal Chemistry – II) Lab

- - 4 60 - 40 100 2

7 Pharmacy 341622 (41) Pharmaceutical Analysis II Lab - - 4 60 - 40 100 2

8 Pharmacy 341623 (41) Pharmacology – II Lab - - 4 60 - 40 100 2

9 Pharmacy 341624 (41) Industrial Visit and Report writing - - 4 - - 100 100 2

19 5 16 530 100 270 900 32

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutical Industrial Management Code: 341611 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Status of pharmaceutical industries in India. Project formulation, evaluation and

implementation. Pharmaceutical Factory Planning and layouts, preparation of flow diagrams, technical data sheets. Management: Concepts on Management, Principles of Management, Administrative and Operative Management Entrepreneurship Development. Material management: Basic principles of Material Management, Purchase, Store and Inventory control. Production Management : Different aspects of Production Management , Performance Evaluation Technique, flow-process, know how process and maintenance. Accountancy: Principles of accountancy, Journal entries and ledger posting, preparation of trial balance, cash book, bank reconciliation statement, rectification of errors, profits and loss account, balance sheet, purchase, keeping and pricing of stocks, treatment of cheques, bill of exchange, promissory notes and hundies, documentary bills. Economics: Principles of economics with special reference to the laws of demands and supply, demand schedule, demand curves, general principles of insurance and inland and foreign trade, procedure of exporting and importing goods. Pharmaceutical Marketing: Functions, wholesale, retail, and mail order business ,market research. Salesmanship: Principles of sales promotion, advertising, and ethics of Sales, merchandising, Window display and literature detailing. Reference / Recommend Books:

1. Shukla, S. M., Advanced Accountancy, Mahershwari Sahitya Bhawan, Agra.

2. Gupta, R. L., Advanced Accountancy, Vol. I and II, Sultanchand & Company, New Delhi.

3. Kotler, P., Marketing Management, Prentice Hall of India Limited.

4. Stanton, W. J., Fundamentals of Marketing Tata McGraw Hill Limited, New Delhi.

5. Buskir K. and Richard H., Principles of Marketing – The Management View, Hold

Rinehard and Winston Incorporated, New York.

6. Sherlekar, S. R., Marketing Management, Himalaya Publishing House, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutical Analysis -II Code: 341612 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

The theoretical aspects, basic instrumentation, elements of interpretation of spectra and pharmaceutical application of the following analytical techniques –

1. Polarography

2. Amperometry

3. Chromatography: Paper Chromatography TLC, GLC, HPLC, HPTLC.

4. Ultraviolet and Visible spectrophotometry

5. Infra red spectrophotometry.

6. Fluorimetry.

7. Mass Spectroscopy.

8. NMR Spectroscopy.

9. Atomic Absorption.

10. X- Ray Diffraction.

11. Flame Photometry.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry –VII Code: 341613 (41)

(Medicinal Chemistry – II) Total Theory Periods: 50 Total Tutorial Period – 12 Total Marks in End Semester Exam: 70


The synthesis of selected drugs, mode of action, classification, uses, SAR including

physicochemical and stearic aspects of the following category of drugs: (A) Drugs acting on CNS:

1. General anaesthetics. 2. Hypnotics and sedative. 3. Opoid analgesics. 4. Anti conuvlsants. 5. CNS Stimulants. 6. Anti parkinsonism drugs. 7. Psychopharmacological agents.

(neuroleptics, antidepresants, anxiolytics).

(B) Anti spasmodic and antiulcer drugs, (C) Anticoagulant and Antiplatelet drugs. (D) Vitamins. (E) Diagnostic agents. (F) Pharmaceutical aids .

Principles of drugs design (theoretical aspects). Traditional analog (QSAR), Mechanism based approaches (Computer aided drug design and molecular modeling).

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmacology -II Code: 341614 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Pharmacology and Pathophysiology of Central Nervous System -

a) Neurohumoral transmission in the CNS. b) General Anaesthetics. c) Alcohols and disulfiram. d) Sedative, hypnotics, anti anxiety agents and centrally acting muscle relaxants. e) Psychopharmacological agents (antipsychotics, antidepressants, antimaniacs and

hallucinogens). f) Antiepileptic drugs. g) Anti parkinsonian drugs. h) Narcotic analgesics and antagonists. i) CNS stimulants. j) Drug addiction and drug abuse.

Drug acting on the gastrointestinal tract and Pathphysiology of GIT drugs has to be NPC-

a) Antacids, antisecretory and antiuker drugs. b) Laxatives and antidiarrhoeal drugs. c) Appetite stimulants and suppressants. d) Emetics and antiemetics. e) Miscellaneous : Carminative, demulcents, protectives, adsorbents, astringents,

digestants, enzymes and mucolytics.

Drug acting on the hemopoietic system and pathophysiology of hemopoietic system -

a) Hematinics. b) Anticoagulants, vitamin K and hemostatic agents. c) Fibrinolytic and antiplatlet drugs. d) Blood and plasma volume expanders.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutics -VIII Code: 341615 (41)

Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2 Organization and structure: Organization of a hospital and hospital pharmacy, responsibilities of a hospital pharmacist, pharmacy and therapeutic committee, budget preparation and implementation. Hospital Formulary: Contents, preparation and revision of hospital formulary. Drug Store, Management and Inventory Control:

a. Organization of drug store, types of materials stocked, storage condition b. Purchase and inventory control-principles, purchase procedures, purchase orders, procurement and stocking.

Drug distribution systems in hospitals: Out patient dispensing, methods adopted.Dispensing of drugs to in-patients, types of drug distribution systems. Charging policy, labeling.Dispensing of drugs to ambulatory patients.Dispensing of controlled drugs.

Central Sterile Supply Unit and Their Management: Types of materials for sterilization, packing of materials prior to sterilization, sterilization, sterilization equipment, supply of sterile materials. Manufacture of sterile and nonsterile products: Policy making of manufacturable items, demand and costing, personnel requirements, manufacturing practice, master formula card, production control, manufacturing records. Drug Information Service: Source of information on drugs, disease, treatment schedules, procurement of information, computerized services (e.g. MEDLINE), retrieval of information, medication error. Records and Reports: Prescription filling. Drug profile, patient, medication profile cases on drug interaction and adverse reactions, idiosyncratic case etc. Nuclear Pharmacy: Introduction to radio –Pharmaceuticals, radio-active half life, units of radio activity, production of radio –Pharmaceuticals, preparation of radio – isotopes in laboratory using radiation dosimetry, radio isotopes generators, permissible radiation dose level, radiation hazards and their prevention, specifications for radio – active laboratory. Reference / Recommend Books:

1. Allwodd M.C. and Fell J. T., Text book of Hospital Pharmacy, Blackwell Scientific Publication, Oxford.

2. Hassan W. E., Lea and Febiger, Philadelphia Hospital Pharmacy 3. Merchant H. S., QuadryJ.S., Text book of Hospital Pharmacy, B. S. Shah

Prakashan, Ahemdabad.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry – VII (Medicinal Chemistry – II) Lab Code: 341621 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60


Exp.1 - Exercise based on QSAR.

Exp.2 - Identification of constituents of drugs from the course content.

Exp.3 - Establish the pharmacoepial standards of the drug from the course contents.

Exp.4 - Determination of partition coefficients, molar refractivity & dissociation constant of compounds for QSAR analysis.


1. Foye, W.C. Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia. 2. Wolff, M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New

York. 3. Hansch, C., Comprehensive Medicinal Chemistry, Pergarnon Press, Oxford.

4. Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Test Book of

Organic, Medicinal and Pharmaceutical Chemistry, J.Lippincott Co., Philadelphia

5. Nogrady, T., Medicinal Chemistry-A Biochemical Approach, Oxford University Press, New York, Oxford.

6. Furnis, B.S. (ed.), Vogel’s Text Book of Practical Organic Chemistry, 4th edn.

ELBS, 1980. 7. Kadam & Mahadik’s A Test book of Medicinal Chemistry.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmaceutical Analysis –II Lab Code: 341622 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60 Experiments to be Performed Exp.1 - Preparation of 1 % w/v solution of potassium permanganate.

Exp.2 - Assay of Phenobarbitone.

Exp.3 - Assay of Prochlorperazine tablets.

Exp.4 - Assay of Isoniazide tablet.

Exp.5 - Preparation of calibration curve for potassium dichromate.

Exp.6 - Find out the percentage of borax & boric acid in the given sample.

Exp.7 - Spectrophotometric determination of percent purity of given sample of salicylic

acid.

Exp.8 - Estimation of aspirin through colourimeter.

Exp.9 - Some experiments are based on the TLC.

Exp.10 - Some experiments are based on the paper chromatography.

Exp.11 - Estimation of Na+, K+, Ca++ ions using flame photometry.

Exp.12 - Colourimetric estimation of give sample of salicylic acid.


1. Svehla, G. Vogel’s Text Book of Micro and Semi Micro Qualitative Inorganic Analysis, Orient Longman, Hyderabad.

2. Beckett, A.K. and Stenlake, J.B., Practical Pharmaceutical Chemistry, The

Athlone Press of the University of London. 3. Chatten, L.G., Text Book of Pharmaceutical Chemistry, Marcel Dekker, New

York. 4. Silverstein, R.M., Bassier, G.C., and Morril, T.C., Spectrophotometric

Identification of Organic Compounds, John Wiley and Sons Inc. 5. Ewing, G.W., Instrumental Methods of Chemical Analysis.

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University, Bhilai Semester: B. Pharma. VI Sem. Branch: Pharmacy Subject: Pharmacology – II Lab Code: 341623 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60 Experiments to be Performed Exp.1 - To study the different routes of administration or drugs in mice.

Exp.2 - To study the effect ofpentobarbital on righting reflex in mice.

Exp.3 - To study the effect of chlorpromazine on the locomotar activities of mice using actophotometer

Exp.4 - To study the apomarphine induced compulsive behaviour in mice.

Exp.5 - To study the analgesic effect of morphine in mice using the tail flick method.

Exp.6 - To study the analgesic effect of morphine in mice using hot plate method.

Exp.7 - To study the analgesic effect of morphine against acetic acid induced writhing in mice.

Exp.8 - To study the antianxiety effect of diazepam in mice using elevated plus, maze apparatus.

Exp.9 - To study the effect or physostigmine and atropine on ciliary movement in from buccal cavity.

Exp.10 - To study the antisecretory and ulcer protective effect of cimetidine in pylorus ligated rats.

Exp.11 - To study the muscle relaxant of diazepam in mice using rostarod apparatus.

Exp.12 - To study the effect of hepatic microsomal enzyme induction on the duration of action

pentobarbital sodium.

Exp.13 - To study the blood and plasma volume expanders.

Exp.14 - To study the effect of proton pump inhibitors on gastricacid reduction.

Exp.15 - To study the anxiolytic effect of diazepam in mice mirrored chamber apparatus.



2. Satoskar, R.S. and Bhandarkar, S.D., Pharmacology and Pharmacotherapeutics. 3. Tripathis, K.D., Essentials of Medeical Pharmcology. 4. Rang, M.P. Dale, M.M. and Riter, J.M, Pharmacology, Churchil Livingstone. 5. F.S.K. Barar’s text book of Pharmacotherapeutics S.Chand Publication Delhi. 6. Paul, L., Principles of Pharmacology, Chamman and Hall. 7. Herfindal, E.T. and Hirschman, J.L., Clinical Pharmacy and Therapeutics, William and Wilkins. 8. Katzung, B.G., Basic and Clinical Pharmacology, Prentice Hall International

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY, BHIALI

Scheme of Teaching and Examination Bachelor of Pharmacy

VII – Semester

Periods Per Week

Scheme of ExamTheory / Practical

Credits L+(T+P)/2 S.No. Board of

Study Subject Code

(New) Nomenclature and Name of the

Subject L T P ESE CT TA Total

Marks

1 Pharmacy 341711(41) Pharmaceutics IX (Pharmaceutical Technology I) 4 1 - 70 20 10 100 5

2 Pharmacy 341712(41) Pharmaceutics X (Pharmaceutical Jurisprudence) 4 1 - 70 20 10 100 5

3 Pharmacy 341713(41) Pharmaceutical Chemistry VIII(Medicinal Chemistry-III) 4 1 - 70 20 10 100 5

4 Pharmacy 341714(41) Pharmacognosy IV 4 1 - 70 20 10 100 5

5 Pharmacy 341715(41) Pharmacology III 3 1 - 70 20 10 100 4

6 Pharmacy 341721(41) Pharmaceutics IX (Pharmaceutical Technology I) Lab - 4 60 - 40 100 2

7 Pharmacy 341722(41) Pharmacognosy IV Lab - 4 60 - 40 100 2

8 Pharmacy 341723(41) Pharmacology III Lab - 4 60 - 40 100 2

9 Pharmacy 341724 (41) Minor Project - - 4 70 - 30 100 2

Total 19 5 16 600 100 200 900 32 Minimum Pass Marks: Duration of Theory Papers: 3 Hours. (A)Theory and Sessional (combined): 50 Percent (B) Practical and Sessional (combined): 50 percent

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY, BHILAI

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutics -IX (Pharmaceutical Technology –I) Code: 341711 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2 Formulation considerations, technology involved, equipment (machine) employed, layouts, problems to be encountered, packaging and evaluation of following dosage forms.

1. Solid Dosage Forms- Tablets, Tablets coatings and Capsules. 2. Liquid Dosage Forms- Liquid Orals, Dry Syrups. 3. Semisolid Dosage Forms- ointments, Creams, Suppositories, Gels. 4. Sterile Dosage Forms- Parenteral (Small Volume Parenterals & Large Volume Parenterals) and

ophthalmic Preparations. 5. Pharmaceutical Aerosols

Requirements of GMP and cGMP and Regulatory controls. Blood Products and Plasma Substitutes: Collection, processing and storage of whole human blood, concentrated human RBC, dried human plasma, human normal immunoglobulin, plasma substitutes, ideal requirements, PVP, Dextran, etc. for control of blood pressure, Surgical products: Definition, surgical cotton, surgical gauzes, bandages, adhesive tapes, absorbable and non absorbable sutures, ligatures and catguts, Medical prosthetics and organ replacement materials.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutics -X (Pharmaceutical Jurisprudence) Code: 341712 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

A brief review of drug and pharmaceutical industries and drug legislation in India.

An elaborate study of the following:

a) Pharmacy act b) Drugs and Cosmetics Act and Rules c) Medicinal and toilet preparations (excise duties) act and rules d) Narcotic drugs and psychotropic substances act and rules e) Essential commodities and drug price control order-new drug policy f) Drugs and magic remedies (objectionable advertisement) act

A brief study of the following:

a) Poisons act and rules b) Medical termination of pregnancy act and rules c) Prevention of cruelty to animals act d) State shops and establishments act and rules e) Insecticides act f) AICTE act g) Factory act h) Minimum wages act i) Patent act

A brief study of various prescription / non-prescription products, Medical / Surgical accessories, diagnostic aids, appliances available in the market. Note: Latest amendments of all the above acts and rules should be covered.


1. Jain, N.K., Text Book of Forensic Pharmacy, Vallabh Prakashan, New Delhi. 2. Mithal, B.M., Text Book of Forensic Pharmacy, national Book Depot, Calcutta. 3. Report of Drug Enquiry Committee. 4. Bare Acts Pertaining to Syllabus.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutical Chemistry -VIII (Medicinal Chemistry – III) Code: 341713 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2 The synthesis of the selected drugs, mode of action, classification, uses, SAR of the following category of drugs:

A) Steroids and related drugs. Steroidal nomenclature and stereochemistry, androgen and anabolic agents, estrogens and progestational agents adrenocorticoids.

B) Diuretics and cardiovascular drugs. C) Antimetabolites (including sulphonamides). D) Chemotherapeutic Agents. E) Anti-viral Agents. F) Immuno- suppresive and anti HIV agents. G) Amino acids, Protiens and peptide hormones. H) Anti-neoplastic agents. I) Thyroid and Antithyroid Drugs. J) Insulin and Oral hypoglycemic agents. K) Drugs affecting uterine motility, oxytocins (including prostoglandins and Ergot alkaloids).


1. Foye, W.C., Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia.

2. Wolff, M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New York.

3. Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Text Book of Organic, Medicinal and Pharmaceutical Chemistry, J.Lippincott Co., Philadelphia.

4. Nogrady, T., Medicinal Chemistry-A Biochemical Approach, Oxford University Press, New

York, Oxford.

5. Kar, A., Medicinal Chemistry, Willey Eastern Ltd., New Delhi. 6. Patrick, G., An Introduction to Medicinal Chemistry, Scientific Distributors, Mumbai. 7. Malone, Dyson and Purey, May’s Chemistry of Synthetic Drugs.

8. Parimoo, P., Text Book of Medicinal Chemistry, CBS Publishers and Distributors, New

Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmacognosy -IV Code: 341714 (41) Total Theory Periods: 50 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

General introduction, classification and brief description of different chromatographic techniques with detailed emphasis on application of TLC, HPLC and HPTLC in the evaluation of herbal drugs including finger printing methods.

Industrial production and analysis (assay in natural sources, extracts and products) of

phytoconstituents of pharmaceutical importance like; Quinine, Calcium Sennosides, Podophyllotoxin, Taxol, Artemisine, Diosgenin, Atropine, Ergometrine, Digoxine, Papain Glycerrhetinic acid Morphine, Vincristine, Ephedrine.

Utilization of aromatic plants and derived products with special reference to isolation of Sandalwood oil, Mentha oil, Vetiver oil, Eucalyptus oil and Lemongrass oil. Historical development of plant tissue culture, their types, nutritional requirements, growth and maintenance. Application of PTC in Pharmacy.

An introduction of marine Pharmacognosy and novel agents from marine sources. Herbs as health foods.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmacology -III Code: 341715 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2 Pharmacology and Pathophysiology of Cardiovascular System –

a) Digitalis and Cardiac glycosides. b) Antihypertensive drugs. c) Antianginal and Vasodilator drugs including Calcium channel blockers and β-adrenergic

antagonists. d) Antiarrythmic drugs. e) Antihyperlipedemic drugs. f) Drugs used in the therapy of shock.

Drugs Acting on the urinary System – Diuretics, fluid and electrolyte balance. Pharmacology and Pathophysiology of Endocrine System –

Hypothalamic and pituitary hormones. Thyroid hormones and antithyroid drugs, parathormone, calcitonin and vitamin D

Insulin, oral hypoglycemic agents and glucagon.

a) ACTH and Corticosteroids. b) Estrogens, anti-oestrogens, progestins and oral contraceptives. c) Androgens and anabolic steroids. d) Drugs acting on the uterus.

Chemotherapy and Cardiovascular System –

1. General principles of chemotherapy 2. Sulfonamides and co-trimaxazole 3. Antibiotics-Penicillin,Cephalosporins,Betalactumstetracyclines,Aminoglycosides,

Choloramphenicol, Erythromycin, Quinolones and Miscellaneous antibiotics. 4. Chemotherapy of tuberculosis, leprosy, fungal diastase, viral diseases, urinary tract infections and sexually transmitted diseases 5 Chemotherapy of malignancy and immunosuppressive agents

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY,

BHILAI

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject : Quality Assurance And Pacakaging Technology: Code: 3417631 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

A) Quality control and Quality assurance. Sources and control of quality variation. Control and assurance of manufacturing practices and finished products. Quality assurance during Packaging operation.

B) New concepts in pharmaceutical packaging. Packaging materials with special reference to

polymers, metals glass and plastics, control of packaging materials. Control of packaging materials.

C) Blister and Strip packaging. Testing of containers and closures, Pharmacopoeial tests and

specifications. Defects in Packages. Stability of packages and packaging materials.

D) Sterilization of pacakaging materials. Packaging of parenterals, ophthalmic and aerosols. Legal requirement.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject : Drug Regulatory Affirs And Therapeutic Drug Code: 3417632 (41)

Monitoring: Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

History of the Federal Food Drug and Cosmetic Act. Definition of drug, New drug, Label, New animal drug under the Federal Food, Drug and Cosmetic act. New drug, NDA, ANDA, SNDA, Recalls, GMP, FDA. Intellectual and Industrial property. Patent Information resources in pharmacy and the Pharmaceutical Sciences. Drug literature, Clinical analysis. Bioavailability and Bioequivalence testing, Adverse Drug Reaction and its monitoring. Drug interactions, Drug abuse. Design of dosage Regimens.

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutics – IX (Pharmaceutical Technology – I) Lab Code: 341721 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60

Experiments to be Performed :

Exp.1 -Prepare & submit effervescent granules.

Exp.2 -Prepare Aspirin tablets by wet granualation method & evaluate.

Exp.3 -Prepare capsule by different type & its evaluate.

Exp.4 -To study the effect of pH on stability of Aspirin.

Exp.5 - Prepare tablets by direct compression method.

Exp.6 -Prepare & submit ophthalmic preparion

Exp.7 - Evaluation and comparison of marketed dosage form

Exp.8 - Moisture peak up study ofsomemarketed product

Exp. 9 -Determine the effect of different concentration of binder ( 3%, 5% and10 %

of povidone and starch paste )on the hardness and dissolution rate of ascorbic tablet.


1. Rawlins, E.A., Text Book of Pharmaceutics, Baillier Tindall.

2. Lachman L., Liberman, H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Lea and Febiger, Philadelphia.

3. Pharmacopoeia of India, Ministry of Health and family Welfare, Govt. of India, New

Delhi. 4. Banker G.S. and Rhode C.T., Modern Pharmaceutics, Marcell Decker Inc., New York. 5. S.J. Carter’s tutorial Pharmacy, CBS Publication, New Delhi. 6. Reminton’s The Science and practice of Pharmacy, 20th Edition, Vol. I & II, Published

by Philadelphia College of Pharmacy and Science

www.Pharmainfo.Net

www.Pharmainfo.Net


BHILAI

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmacognosy – IV Lab Code: 341722 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60 Experiments to be Performed : Exp.1 - Isolation of nicotine from tobacco. Exp.2 - Isolation of caffeine from tea leaves. Exp.3 - Isolation of piperine from black pepper. Exp.4 - Isolation of ammonium glycerrhizinate from liquorice root. Exp.5 - Isolation of sennoside from senna leaves in from of calcium salt. Exp.6 - Extract salonine from potato tubers. Exp.7 - Isolation of atropin from datura leaves. Exp.8 - Evaluation of herbal drug preparation using the TLC & paper chromatography. Exp.9 - Isolation of mentha oil. Exp.10 - Isolation of eucalyptus oil. Exp.11 - Isolation of Aloin from Aloe. Exp.12 - Determine veinistate and veinlet termination number of given sample of leaf (datura). Exp.13 - Determination of moisture content of the given sample (senna). Exp.14 - Determine the foaming index of given drug pipripiper longam. Exp.15 - Determine the Alcohol soluble extract value of the given sample. Exp.16 - Determination of hemolytic index value . Exp.17 - Perform TLC of given sample. Exp.18 - Determine the Saponification value of given sample.


1. Trease, G.E. and Evans, W.C., Pharmacognosy, Bailliere Tindall, Eastbourne, U.K.

2. Tayler, V.C., Brady, L.R. and Robers, J.E., Pharmacognosy, Lea and febiger, Philadelphia 3. Shah, C.S. and Quar\dry, J.S. A text book of Pharmacognosy, B.S. Shah Publishers,

Ahmedabad. 4. Kokate, C.K., Purohit, A.P., and Gokhale, S.B., Pharmacognosy, Nirali Prakashan, Pune. 5. Wallis, T.E. Text Book of Pharmacognosy, Jand A Churchill Limited, London.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII SEM. Branch: Pharmacy Subject: Pharmacology - III Lab Code: 341723 (41) Total Practical Periods: 50 Total Marks in End Semester Exam: 60 Experiments to be performed: Exp.1 - To study the cardiovascular system of frog. Exp.2 - To study the cardiovascular system of Rabbit. Exp.3 - To study the cardiovascular system human being. Exp.4 - To draw and study the electrocardiograph. Exp.5 - To study the inotropic and chronotropic effects of drugs on isolated frog heart. Exp.6 - To study the effects of drugs on normal and hypodynamic frog heart. Exp.7 - To study the effect of noradrenaline, acetylcholine and isoprenaline on the coronary blood flow

of rat isolated heart. Exp.8 - To study the noradrenaline acetylcholine and isoprenaline on the heart rat using rat isolated

heart. Exp.9 - To record the effect of acetylcholine and noradrenaline on the blood pressure. Exp.10 - To record the effector acetylcholine and noradrenaline on the blood pressure and

electrocardiography of an anaesthetized rat. Exp.11 - To demonstrate the effect of adrenaline noradrenaline isoprenaline and acetylcholine on the

blood pressure of anaesthetized dog. Exp.12 - To study the effects of blockers on isolated from heart. Exp.13 - To study the chlorothiazide and spironolactone on the excretion of urine. Exp.14 - To record the CRC of oxytocin using rat uterus preparation. Exp.15 - To study the endocrine system.



2. Satoskar, R.S. and Bhandarkar, S.D., Pharmacology and Pharmacotherapeutics. 3. Tripathis, K.D., Essentials of Medeical Pharmcology. 4. Rang, M.P. Dale, M.M. and Riter, J.M, Pharmacology, Churchil Livingstone. 5. F.S.K. Barar’s text book of Pharmacotherapeutics S.Chand Publication Delhi. 6. Paul, L., Principles of Pharmacology, Chamman and Hall. 7. Herfindal, E.T. and Hirschman, J.L., Clinical Pharmacy and Therapeutics, William and

Wilkins. 8. Katzung, B.G., Basic and Clinical Pharmacology, Prentice Hall International

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VEVEKANAND TECHNICAL UNIVERSITY, BHIALI Scheme of Teaching and Examination

Bachelor of Pharmacy VIII- Semester

Periods Per Week


S.No. Board of Study

Subject Code (New)


L T P ESE CT TA Total Marks

Credits L+(T+P)/2

1 Pharmacy 341811(41) Pharmaceutics XI (Pharmaceutical Technology II) 3 1 - 70 20 10 100 4

2 Pharmacy 341812(41)Pharmaceutics XII (Bio-pharmaceutics and Pharmacokinetics)

3 1 - 70 20 10 100 4

3 Pharmacy 341813(41) Pharmaceutical Analysis III 3 1 - 70 20 10 100 4

4 Pharmacy 341814(41) Pharmacology IV (Clinical and Drug Interactions) 3 1 - 70 20 10 100 4

5 Refer Table – I Elective- I 2 1 - 70 20 10 100 3

6 Pharmacy 341821(41)Pharmaceutics XI (Pharmaceutical Technology II) Lab

- 6 60 - 40 100 3

7 Pharmacy 341822(41)Pharmaceutics XII (Bio-pharmaceutics and Pharmacokinetics) Lab

- 6 60 - 40 100 3

8 Pharmacy 341823(41) Pharmaceutical Analysis III Lab - 3 60 - 40 100 2

9 Pharmacy 341824 (41) Major Project - - 6 120 - 80 200 3 Total 14 5 21 650 100 250 1000 30

Minimum Pass Marks: Duration of Theory Papers: 3 Hours. (A) Theory and Sessional (combined): 50 Percent (B) Practical and Sessional (combined): 50 Percent

Table – I

Elective - I

S.No. Board of Study Subject Code Subject

1 Pharmacy 341831 (41) Quality Assurance and Packaging Technology

2 Pharmacy 341832 (41) Drug Regulatory Affairs therapeutic Drugs Monitoring

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University, Bhilai Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Pharmaceutics – XI (Pharmaceutical Technology II) Code: 341811 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Design, development, formulation and evaluation of controlled release formulations. Carriers for drug delivery systems, Prodrugs.

Microencapsulation: Theory, methods, technology and applications. Transdermal Drug Delivery Systems: Theory, formulation and evaluation. Targeted Drug Delivery Systems:

Concept of drug targetting, importance in therapeutics, methods in drug targeting, Nanoparticles, Liposomes, Erythrocytes etc.

Implants and Inserts: Types, design and evaluation, Osmotic pump. Packaging of Pharmaceutical Products and Cosmetics:

Packaging components, types, specifications and methods of evaluation, stability aspects of packaging, packaging equipment, factors influencing choice of containers, legal and other official requirements for containers, Packaging testing.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Pharmaceutics –XII (Bio- pharmaceutics and Pharmacokinetics) Code: 341812 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Introduction to biopharmaceutics and pharmacokinetics development and their role in drug formulation.

Biopharmaceutics Definition, passage of drugs across biological barrier, Physiochemical, Biological and Pharmacaceutical

factors influencing biopharmaceutical performance of drugs. 1. Gastrointestinal absorption of drugs: Passage of drugs across biological membranes, nature of biological

membranes, gastrointestinal absorption mechanisms. 2. Factors affecting drug absorption: Physiological factors, dietary factors, physicochemical factors, pH

partition hypothesis, dosage form factors. 3. Methods of studying gastrointestinal absorption: In vitro and in vivo methods. 4. Drug disposition: Distribution in blood, cellular distribution, plasma protein binding, tissue protein binding. 5. Drug Excretion: Routes of drug excretion, renal excretion of drugs, factors affecting renal excretion, biliary

and salivary excretion of drugs. 6. Drug biotransformation: Pathways of drug metabolism, drug metabolizing enzymes, factors affecting drug

metabolism and drug response, inhibition and stimulation of drug metabolism.

Pharmacokinetics Absorption, distribution, metabolism and excretion of drugs, fluid compartment and circulatory system, protien binding, significance of plasma drug concentration measurement. Compartment Models Model selection criteria, one-compartment and two-compartment models, Wagner-Nelson and loo Riegelman methods for estimation of absorption constants. Curve fittings, regression procedure and area under blood level curves. Clinical Pharmacokinetics Urinary excretions, computation of pharmacokinetic parameters from urine data, hepatic clearance, biliary excretion, excretion ratio, dosage regimen adjustment in patients with and without renal failure, pharmacokinetic drug interactions and their significance in combination therapy. Bioavailability and Bioequivalance

Bioavailability and Bio-equivalance, Federal requirements, Methods of determination of bioavailability using blood level and urinary excretion data, design and evaluations, bioavailability assessment.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Pharmaceutical Analysis –III Code: 341813 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2 Dosage forms evaluation as per monograph with special reference to I.P. Development of new analytical methods. Concepts in validation, validation of manufacturing and analytical equipment, validation of analytical procedures. Documentation: Protocols, forms and maintenance of records in pharmaceutical industries, preparation of documents for new drug approval and export registration to United States, United Kingdom, Europe and Africa. Patent processing and its applications:

Requirement of GLP, ISO 9000, WHO and U.S. F.D.A. Basic concept of quality assurance, quality assurance system, sources and control of quality variation. In-process quality control tests, IPQC problems in Pharmaceutical Industries, Total quality management. Sampling plans, sampling and operating characteristics curves, Interpretation of analytical data. Regulatory control, regulatory drug analysis.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Pharmacology –IV (Clinical and Drug Interactions) Code: 341814 (41) Total Theory Periods: 40 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

Introduction to Clinical Pharmacy Basic Principles of cell injury and adaption- Causes of cell injury, pathogenesis, morphology of cell injury, intra cellular alterations in lipids, proteins and carbohydrates, cellular adaption, atrophy, hypertrophy. Basic Mechanism Involved in the Process of Inflammation and Repair- Alterations in vascular permeability and blood flow, migration of WBC’s, acute and chronic inflammation, brief outline of the process of repair. Basic Concepts of Pharmacotherapy-

a) Clinical Pharmacokinetics Individualization of Drug Therapy. b) Drug Use During Infancy and in the Elderly (Paediatrics and Geriatrics) c) Drug use during Pregnancy. d) Drug induced disease. e) The Basics of Drug interactions. f) General principles of clinical laboratory tests.

Therapeutic Drug Monitoring Concept of essential Drugs and Drug Use, Drug abuse Principles of Toxicology

a) Definition of Poison, general principles of treatment of poisoning particular reference of barbiturates, Opoids, Organophosphorylation and Atropine poisoing.

b) Heavy metals and heavy metal antagonists. Reference / Recommend Books:

1. Herfindal, E.T. and Hirschman, J.L., Clinical Pharmacy and Therapeutics, William and Wilkins. 2. Katzung, B.G., Basic and Clinical Pharmacology, Prentice Hall International. 3. Laurence, D.R. and Bennet, P.N., Clinical Pharmacology, Churchill Livingstone.

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University, Bhilai Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Quality Assurance And Packaging Technology) Code: 341831 (41) Total Theory Periods: 28 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

A) Quality control and Quality assurance. Sources and Control of quality variation. Control and assurance of manufacturing practices and finished products. Quality assurance during Packaging operation.

B) New concepts in pharmaceutical packaging. Packaging materials with special reference to polymers,

metals glass and plastics, control of packaging materials. Control of packaging materials.

C) Blister and strip packaging. Testing of containers and closures, Pharmacopoeial tests and specifications. Defects in Packages. Stability of packages and packaging materials.

D) Sterilization of packaging materials. Packaging of parenterals, ophthalmic and aerosols. Legal

requirement.

www.Pharmainfo.Net

www.Pharmainfo.Net

Chhattisgarh Swami Vivekanand Technical University, Bhilai Semester: B. Pharma. VIII Sem. Branch: Pharmacy Subject : Drug Regulatory Affirs and Therapeutic Drugs Montoring Code: 341832 (41) Total Theory Periods: 28 Total Tutorial Period - 12 Total Marks in End Semester Exam: 70 Minimum number of class tests to be conducted: 2

A) History of the Federal Food Drug and Cosmetic Act. B) Definition of drug, New drug, Label, New animal drug under the Federal Food, Drug and

Cosmetic act.

C) New drug, NDA, ANDA, SNDA, Recalls, GMP, FDA.

D) Intellectual and Industrial property. Patent information resources in pharmacy and the Pharmaceutical Science. Drug literature, Clinical analysis.

E) Bioavailability and Bioequivalence testing. Adverse Drug Reaction and its monitoring. Drug

interactions, Drug abuse. Design of dosage Regimens.


www.Pharmainfo.Net

www.Pharmainfo.Net

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutics -XI (Pharmaceutical Technology- II) Lab Code: 341821 (41) Total Practical Periods: 72 Total Marks in End Semester Exam: 60 Experiments to be Performed :

Formulations, evaluations and stability testing of preparations concerning dosage forms mentioned in theory.


1. Rawlins, E.A., Text Book Of Pharmaceutics, Bailliere Tindall.

2. Lachman, L. , Liberman, H.A. and Kanig, J.L., The Theory and Practice of Industrial Pharmacy, Lea and Febiger, Philadelphia.

3. Liberman, H.A., lachman, L. and Ker Inc. New York.

4. Pharmacopoeia Of India, Ministry of Health and family Welfare, Govt. of India, New Delhi.

5. Avis, K.E., Lachman, L. and Liberman, H.A., Pharmaceutical Dosage Forms-Parenteral Medication Vol.1-2, Marcel Decker Inc., New York.

6. Banker G.S. and Rhode C.T., Modern Pharmaceutics, Marcell Decker Inc., New York.


www.Pharmainfo.Net

www.Pharmainfo.Net

Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutics -XII (Bio- pharmaceutics and Pharmacokinetics)Lab Code: 341822 (41) Total Practical Periods: 72 Total Marks in End Semester Exam: 60 Experiments to be Performed :

Exp.1 Experiments designed for the estimation of various pharmacokineticsparameterswith given data. Exp.2 Invitro evaluation of different dosage forms for drug release. Exp.3 Absorption studies invitro and insitu. Exp.4 Statistical treatment of pharmaceutical data.


1. Gennaro, A.R., ed Remington’s The science and Practice of Pharmacy, Mac Publishing Co. Pennsylvannia, USA.

2. Notari, Biopharmaceutics and Pharmacokinetics an Introduction, 2nd ed Lea & Febiger, NY

1982. 3. Gibaldi and D. Perrier, Pharmacokinetics, 2nd ed, marcel Dekker Inc., NY 1982. 4. Milo Gibaldi. Biopharmacokinetics and Clinical Pharmacokinetics, 3rd., Le & Febizer,

Phidelphia 1984. 5. Brahmankar’s Biopharmaceutics and Pharmacokinetics , Vallabh Prakashan, Delhi. 6. Rowland & Tozer’s Clinical Pharmacokinetics, Concepts and applications,3rd ed., Lea &

Febiger Publication, USA.

www.Pharmainfo.Net

www.Pharmainfo.Net


Semester: B. Pharma. VII Sem. Branch: Pharmacy Subject: Pharmaceutical Analysis -III Lab Code: 341823 (41) Total Practical Periods: 40 Total Marks in End Semester Exam: 60 Experiments to be Performed : Exp.1 Evaluation of dosage formation as per I.P. monograph. Exp.2 Q.C of the herbal drug preparation as per the WHO guideline. Exp.3 Assay of marketed dosage form as per I.P. & USP. Exp.4 Validation of manufacturing and analytical equipments. Exp.5 Preparation of GLP


1. Willing, S.H., IV, Good Manufacturing Practices for Pharmaceuticals, Marcel Dekker Inc., New York.

2. Loftus, B.T. and Nash R., Pharmaceutical Proce3ss Validation, Marcel Dekker Inc., New York. 3. Svehla, g. Vogel’s Text Book of micro and Semi Micro Qualitative Inorganic Analysis, Orient

Longman, Hyderabad. 4. Beckett, A.H. and Stenlake, J.BN., Practical Pharmaceutical Chemistry, the Athlone Press of

the university of London. 5. Pharmacopoeia of India, Ministry of health and Family Welfare, Govt. of India, New Delhi.

www.Pharmainfo.Net

www.Pharmainfo.Net

CHHATTISGARH SWAMI VIVEKANAND … Chhattisgarh Swami Vivekanand Technical University Semester: 1st Branch: B. Pharmacy Subject: Pharmaceutics-I (Introduction to Pharmaceutics) Code

Documents