Chemir Analytical Services

A n a l y t i c a l S e r v i c e s



cGMP/GLP COMPLIANT • ISO 9001 CERTIFIED • FDA REGISTERED • DEA LICENSED

S C I E N T I F I C S O L U T I O N S W I T H PA S S I O N A N D P U R P O S E

D e f o r m u l a t i o n

M a t e r i a l s I d e n t i f i c a t i o n

F a i l u r e A n a l y s i s

L i t i g a t i o n S u p p o r t

C o n s u l t i n g

WHAT’S YOUR CHEMICAL CHALLENGE?

For over 50 years Chemir Analytical Services has been defining problems, developing solutions and producing reliable, meaningful results for nearly 7000 clients worldwide.

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Our independent non-routine analytical laboratory

solves challenging problems for such industries as food

and beverage, pharmaceutical, medical device, personal

care, polymers, plastics, packaging, coatings and more.

OUR MISSION We strive to maintain the highest degree of scientific excellence, state-of-the-art instrumentation, quality standards and customer service.

SCIENTIFIC EXCELLENCE

Our team of scientists designs and implements investigations that result in accurate, reliable data with meaningful interpretations.

STATE-OF-THE-ART INSTRUMENTATION

Our instrumentation is maintained and calibrated regularly to ensure reliable results.

FOCUS ON QUALITY

Our facility is ISO 9001 certified, FDA registered and cGMP/GLP compliant. Our quality mission is to achieve total customer satisfaction by delivering on-time, accurate analyses that meet each customer’s needs.

CUSTOMER SERVICE

Our scientists ask the right questions, listen to our clients, and provide practical solutions. Results are provided in a timeframe consistent with customer requirements, including rush turnaround if needed.

ANALYTICAL SERVICES ................................2

- Deformulation- Materials Identification- Contaminant Identification- Failure Analysis- Industrial and Consumer Product Testing- Polymer Analysis- Emergency Services

SOLUTIONS FOR INDUSTRY ........................6

- Food and Beverage- Home, Health and Beauty- Pharmaceutical- Medical Device- Plastics and Composites- Packaging- Coatings, Adhesives and Sealants- Working Together LITIGATION SUPPORT

AND CONSULTING ................................... 10

- Litigation Support- Consulting Services Resources ........................................12

Customers .......................................14

Case Studies ...................................16

Terms and Conditions .......................17

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Chemir scientists take a customized approach to chemical

identification, deformulation and materials testing, utilizing

a wide variety of techniques and instrumentation.A N A L Y T I C A LS E R V I C E S

DEFORMULATION

Deformulating products and materials is our specialty. Also known as reverse engineering, deformulation is the separation, identification and quantitation of ingredients in a formulation.

We have successfully deformulated a variety of products such as:- Drug products including oral, topical and liquid

dosages- Personal care products including topical gels,

lotions, creams and ointments- Detergents and cleansers- Coatings- Adhesives (PSA, hot melt and water borne) and

sealants (Epoxy, PU, silicone) - Rubber products (natural rubber, EPDM, TPE,

Neoprene, SIS, SBS, NBR, EVA, PUR, silicone and more)

- Plastics (PP, PE, PMMA, Nylon, PU, flexible and rigid PVC, copolymer and blends, degradable PP and PE)

- Specialty products (multiple layer films, high temperature engineered products)

- Composites (glass reinforced, carbon or graphite filled, Kevlar fiber reinforced and more)

Our clients often come to us with a knowledge of the types of ingredients in their target formula, such as the wetting agent, co-solvent or surfactant. Using the client’s information along with our scientific expertise, we can create a working “recipe” that meets a variety of needs including:- Competitive product characterization- Identification of batch to batch variations- Comparative analysis of “good” and “bad” samples- Patent infringement litigation

Our experienced chemists are kept up-to-date with the latest methods and have developed techniques for unraveling complicated formulations.

Unlike other deformulation providers, Chemir’s deliverable is a complete table of ingredients, including quantities and percentages of components. After contacting our clients to discuss the results, we provide analysis and interpretations in a concise, bound final report containing a summary, conclusions and any original data.

Deformulation analysis of commercial products is provided

for informational purposes only. Chemir Analytical

Services strongly recommends review of state and federal

laws, trademarks, copyrights and patent situations by the

customer prior to use of such information.

MATERIALS IDENTIFICATION

Materials identification can be used to determine the components of an unknown material, confirm the identity of a suspect material, or to identify differences in similar materials.

An unknown material is often the underlying cause of many difficult problems. The goal of material identification is to understand the chemistry of the major components. Chemir has developed expertise in identifying and characterizing unknowns through analytical techniques and accurate interpretations.

We tackle organic material identification using FTIR spectroscopy to determine the chemical family and functional groups through library matching and fundamental spectral interpretation. We can also identify the inorganic components using an SEM equipped with an EDXA elemental analysis technique.

Once the data is collected, our experienced scientists interpret the information. They are skilled at effectively communicating information to our clients and providing useful results regarding the unknown material.

CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM2

CONTAMINANT IDENTIFICATION

When an unknown material is found in a product, manufacturers need to know the source of contamination. Contaminant identification projects involve the determination of components at low concentrations such as ppm or even ppb levels.

A strategic technical approach is required to identify the unknown contaminant by using a comparison study between a control and suspect sample. The technical approach is dependent on the sample matrix and the suspected level of contamination. Often, we start with a general screen of the control and suspect samples using GC/MS and LC/MS. Depending on the results, we may need to isolate the contaminant from a large amount of sample to allow for analysis using FTIR and NMR spectroscopy. Once identification is complete, we can further quantify the contaminant in the sample matrix.

Typical contaminant identification projects have involved off-odor/flavor investigations, off-color problems, or foreign particles in a product. Some sources of contaminants have been from the environment, improper storage of the product, or poor quality raw materials. We work closely with our clients to trace the source of contamination and develop a corrective action program.

Deformulation - Materials Identification -

Contaminant Identification -

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Our independent laboratory and expert scientists design

experiments that provide answers to industrial challenges.A N A L Y T I C A LS E R V I C E S

FAILURE ANALYSIS

From consumer goods to industrial machinery, the scientists at Chemir Analytical Services can meet your failure analysis testing needs. We will help you define the problem and recommend solutions. A product failure may include premature breakage, discoloration or even an unexpected odor.

We can help with new or ongoing failures. A sample of the “good” vs. “bad” product is often sent to our lab for comparison, but onsite investigations of processes may also be necessary.

Products tested include packaging, plastics, adhesives, metals, coatings, composites, laminates and more.

Chemir’s final report includes conclusions, results and all the original technical data acquired during the analysis including photographs, chromatograms and spectra. Our years of experience investigating material and product failures allow us to recognize the indicators of failure and follow these leads to their root cause.

INDUSTRIAL AND CONSUMER PRODUCT TESTING

We provide customized product testing for individual components as well as finished manufactured products. We can investigate advertised product claims as well as conduct performance comparisons. Other product testing includes durability and resistance testing, as well as corrosion, chemical solvent resistance, stain and burn resistance, flammability, and fire properties.

The effects of the environment can have significant impact on the lifetime and functionality of your product. Chemir can simulate environmental conditions in order to understand the effect on your product’s performance.

Testing services include:- Degradation- Product lifetime- Product resistance- Weathering controlled accelerated exposure

Chemir has developed, validated and transferred methods for the analysis of inorganic materials. These include metals, sulfates, phosphates, chlorides, fluorides and other anions.

Materials tested include automotive parts, engines, fabrics, plastic components, toys, sporting goods and appliances.


When unforeseen quality issues occur, Chemir can help.

Failure Analysis - Industrial and Consumer Product Testing -

Polymer Analysis - Emergency Services -

POLYMER ANALYSIS

When problems arise with the development, production or function of polymer based products, Chemir has the tools and experience to help. We have investigated a wide range of polymeric materials including:- Thermoplastics- Thermosets- Elastomers- High-performance polymers- Specialty polymers - Composites- Polyurethanes- Adhesives and sealants

Depending on our clients’ needs, we can offer a strategic combination of physical and chemical testing to answer specific questions. Physical properties analyzed have included:- Tensile properties - Adhesive strength - Compressibility - Cross-sectional multiple layer film thickness - Melt Flow Index - Thermal properties (including glass transition, melting point, thermal expansion and crystallinity)

Our chemical testing capabilities range from obtaining basic information to more detailed and structurally specific results such as:- Chemical family, including base polymer characterization - Molecular weight distribution - End group analysis - Co-polymer backbone chemistry, comonomer contents/ratios, polymer blends - Additive analysis

EMERGENCY SERVICES

When unforeseen quality issues occur, Chemir can help. Our scientists are available 24/7 to solve complex, non-routine problems using a customized approach. Whether it is identifying the source of an off-odor or resolving a product failure, Chemir has a solid reputation for delivering results during emergency situations. Our analytical investigations provide quick and reliable answers needed to manage a crisis.

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Our scientists investigate challenges with products

that impact health and well-being.S O L U T I O N SF O R I N D U S T R Y

FOOD AND BEVERAGE

Chemir Analytical Services has helped hundreds of food and beverage manufacturers with challenging food testing issues including:- Contaminant identification including ingredient cross-contamination- Off-colors, off-flavors, or off-odors analysis- Packaging trouble-shooting- Extractables and leachables testing- Foreign object identification- Emergency response- Hazard analysis- Toxicity risk assessment

In addition, our experts provide litigation support for food product liability issues and other legal challenges.

Examples of ways we have helped food manufacturers:- Identified diet soda product contamination- Determined the cause of bursting potato chip bags- Analyzed levels of benzene in a beverage- Off-odor source identification in produce- Performed contaminant identification in an imported food product- Assisted poultry and meat processors with toxicity risk assessment

HOME, HEALTH AND BEAUTY

Chemir has helped companies with challenging issues in the personal care, cosmetic, fragrance, soap and detergent industries. We provide custom formulation, stability studies and pilot-scale, semi-commercial manufacturing.

From concept to finished product, our formulation scientists help manufacturers create new products or improve existing ones. Our staff has years of experience working with a diversity of matrices. Unlike other contract facilities, our clients retain the option to full rights of their final product formulation.

We also partner with personal care product entrepreneurs, developers and marketing firms to take their ideas from concept to commercialization.

Chemir Analytical Services has assisted companies in the health and beauty industry by providing:- Deformulation and reformulation of a discontinued product- Formulation development and pilot batch production of a mouthwash- Investigation into an off-color nail polish- Characterization of an unknown substance in a cosmetic product- Quantification of ingredients in a soap formulation

CHEMIR ANALYTICAL SERVICES • 1.800.659.7659 • WWW.CHEMIR.COM

Food and Beverage - Home, Health and Beauty -

Pharmaceutical - Medical Device -

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Food and Beverage - Home, Health and Beauty -

Pharmaceutical - Medical Device -

PHARMACEUTICAL

Our services to the pharmaceutical industry are focused on solving difficult problems. Chemir scientists are experienced at designing and performing investigative projects involving contamination or product failure issues. Our expertise in deformulation and polymer analysis has provided many companies with solutions to troubling product challenges.

Chemir also offers analysis and expert witness services for cases involving pharmaceutical patent infringement. Our chemists are experienced in the courtroom and are skilled in explaining technical methods and results in clear and understandable terms.

Examples of pharmaceutical challenges Chemir scientists have resolved include:- Determination of the cause of black speck contaminants in aspirin - Deformulation of an OTC product for a generic drug manufacturer- Investigation into an off-color of a liquid pharmaceutical product- Litigation support for a patent infringement case involving active pharmaceutical ingredients

MEDICAL DEVICE

Chemir Analytical Services investigates medical device materials and performance issues involving polymers, plastics, metals, organics, inorganics and more. Our scientists have solved difficult problems with a wide variety of device products including implantables, flexible tubing, containers, protective devices, and more.

When medical device issues involve litigation support, Chemir’s scientists are available to review data, provide independent testing and offer expert witness services.

Examples of problems solved for the medical device industry:- Analysis of polymeric materials to evaluate products for resin composition - Investigation of product failure of a polyurethane catheter - Deformulation of a detector strip in support of an intellectual property case - Polymer analysis to investigate biodegradation of an implanted device

Our facility is cGMP compliant, FDA registered

and DEA licensed, and is centrally located in

St. Louis, Missouri.

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Chemir has been solving tough problems for manufacturers for over 50 years.S O L U T I O N SF O R I N D U S T R Y

PLASTICS & COMPOSITES

Chemir offers a complete range of analyses for plastics and composites. These materials can be found in a wide variety of industries including automotive, sporting goods, toys, industrial products, construction materials, consumer goods and more. Our scientists have addressed issues such as:- Premature breakage of a plastic tubing- Failure analysis of a cracking door- Deformulation of a competitor’s multi-layered film product- Identification of the source of odor in a children’s toy- Characterization of an unknown contaminant in a polyurethane product

PACKAGING

Packaging systems can pose challenging problems for manufacturers. We solve complex problems with cartons, cans, bottles, pouches, vials, bags and more. We have helped manufacturers in the research and development phases as well as trouble-shooting finished products.

Our comprehensive instrumentation, wide range of capabilities and extensive experience enable us to test a package and also analyze its contents, labels, adhesives, closures, resins, pigments, additives, shrink film and more.

Some examples of our problem solving capabilities include:- Determination of the cause of “ballooning”

of a sealed pouch packaging system - Identification of the source of delamination

of a multi-layered product package- Identification of the composition of a film that developed on a bottle after hot product filling- Deformulation of ink on a package label- Finding the cause of pinhole formation in bags- Comparison of two adhesive products to

demonstrate a difference in the applied glues- Isolation of an unusual odor from a package- Testing of competing package sealing systems

in a patent infringement case- Determination of the cause of adhesive failure occurring under high temperatures


We have helped manufacturers in the research and development

phases as well as trouble- shooting finished products.

Plastics and Composites - Packaging -

Coatings, Adhesives and Sealants - Working Together -

COATINGS, ADHESIVES AND SEALANTS

Our scientists investigate a wide variety of issues for the coating industry. We have helped manufacturers, distributors, importers and retailers with customized chemical analysis for: - Paints and coatings- Adhesives and sealants- Inks and dyes- Other industrial chemicals Chemir has helped companies with deformulation and reformulation of coatings products, as well as trouble-shooting difficult challenges. We can also assist with formulation projects, from bench scale up to toll production. WORKING TOGETHER

Our goal is to become an extension of your research, product development or quality control team. Clients come to Chemir from a broad spectrum of industries and job functions.

Quality Assurance/Quality Control: Questions from QA/QC professionals often stem from unforeseen quality issues such as contamination, poor product performance or premature failure. Our scientists can help QA/QC develop and evaluate methods for a proactive quality program, as well as investigate unusual hard-to-solve problems.

CEOs/Presidents: Company leaders are most concerned with risk, both financial and legal. Chemir has worked with corporate executives faced with patent disputes, customer complaints, product liability cases, safety concerns and more.

Production Managers: When production lines are shut down or mechanical equipment malfunctions, managers need reliable answers. Chemir Analytical Services can perform investigations to determine the root cause of failures, avoiding costly delays and resuming operations.

Entrepreneurs/Research & Development: Chemir helps entrepreneurs accomplish their dreams. Our staff can develop an idea for a new product from bench-top to semi-commercial production. We have assisted R&D departments research ingredients, determine procedures and make necessary adjustments to match the customer’s idea.

A PARTNERSHIP

When you call our facility you are connected with a Director of Technical Services, an experienced scientist who will ask the right questions, listen and develop investigations to solve your problem. We are proud of our warm and personal service. Our scientific staff provides regular updates to our clients throughout the course of the project. Working as a partnership, we can recommend changes in materials, reformulation or manufacturing processes.

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Complex problems may require outside experts. Chemir can provide testing

and testimony in legal cases, as well as consulting on challenging issues. L I T I G A T I O N S U P P O R T A N DC O N S U L T I N G

LITIGATION SUPPORT SERVICES

When challenges involve litigation, our scientists can help. With experts in many disciplines and industries, we provide the technical and professional expertise necessary to support legal challenges. Ph.D. chemists will design independent investigations, supervise laboratory analyses and write comprehensive reports. They are skilled in explaining technical methods and results in clear and understandable terms.

Litigation support services include:- Evaluation of cases- Method development and testing- Interpretation of technical data- Critical review of data- Literature searches- Trial preparation- Depositions and trial testimony

Our chemists have helped resolve issues in intellectual property disputes. As patent expert witnesses, our scientists have offered testimony in patent infringement disputes and trade secret litigation.

Chemir’s materials scientists have also offered forensic chemical and litigation support in product liability defense cases, insurance claims and product failure litigation.

Some examples of litigation support projects:- Resolved a coatings patent infringement issue by deformulation - Resolved insurance claims for fire damages through

analysis of explosives and fuels- Expert consulting for chemical spill at a large company- Performed failure analysis in a case involving premature plastic pipe breakage- Reviewed opposing data in a personal injury lawsuit- Determined the root cause of failure for a window manufacturer in a product liability case- Conducted flame testing on a consumer product to support a client’s personal injury claim


With experts in many disciplines and industries, we provide the technical and professional expertise necessary to support legal challenges.

CONSULTING SERVICES

Whether it is at your facility, here in our laboratories, part of a conference call, or by written report, Chemir’s staff is available for consultation on a variety of projects. Our independent consultants bring new perspectives and experiences valuable for problem solving and product improvement such as:- Defining a manufacturing problem- Working with your staff in problem solving- Recommending different testing procedures or methods- Defining research or quality protocols- Providing expertise in product or process development- Investigating a cause of product failure

Our consultants regularly participate in conferences and panels in order to keep up with the latest technical developments in their field and are regarded as leaders in their respective industries. Our consulting experience includes:- Chemical analysis and techniques- Polymers including deformulations, synthesis, additives, alloys, blends and formulations- Consumer products- Fine organic chemicals- Polyolefins, nylons, multilayer films- Advanced composites, carbon fibers- Manufacturing processes

Litigation Support Services - Consulting Services -

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Our experienced staff of high level scientists, rigorous quality systems

and extensive instrumentation enables us to provide industry leading

quality and service.O U R R E S O U R C E S

PEOPLE

Our staff of Ph.D-level chemists, along with advanced degreed scientists, collaborate to offer creative solutions to non-routine problems. They bring practical industrial knowledge, as well as advanced academic credentials to each project.

FACILITY

Our centrally located facility in Maryland Heights, MO, a suburb of St. Louis, has more than 20,000 sq. ft. of laboratory space equipped with state-of-the-art instrumentation.

QUALITY

Chemir Analytical Services maintains a Quality Management System based on ISO 9001:2000 as well as other certifications.

Our quality system, documented procedures and analytical methods reflect our quality policy statement: To achieve total customer satisfaction by delivering on-time, accurate analyses that meet each customer’s needs.

The primary goals of our quality program are continuous improvement, reliable results and on-time, error free reporting.

Continual Improvement: We strive to improve our processes, methods and procedures by the following means: - Ongoing training programs to help us keep abreast of new technologies, regulations and industry trends and to improve our processes

- Quality assurance coordinators to work closely with management and technical staff in reviewing analyses for compliance with standards

- Quality team meetings to provide a forum for addressing questions and concerns on quality issues

Ensuring Reliable Results: Our quality system is focused on obtaining accurate results.- The use of Standard Operating Procedures (SOPs)

to ensure uniformity in routine operations- Installation, Operation and Performance

Qualification (IQ/OQ/PQ) of analytical instrumentation for applicable regulatory work

- The use of standard or validated methods for analyses when available

- Continuing surveillance of published guidance documents to ensure adherence to current regulatory policies that impact our clients

Error Free Reporting: The quality of our reported data is critical.- Documenting all facets of analysis- Communicating any questionable or non-

conformance results to the customer within 24 hours- Following procedures and complying with standards- Auditing data internally when regulatory compliance

is required

Our facility is:

- ISO 9001:2000 Certified

- FDA Registered

- cGMP/GLP Compliant

- DEA Licensed


People - Facility -Quality -

Equipment -

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EQUIPMENT Our clients can be assured their samples will be investigated using state-of-the-art instrumentation in the areas of chromatography, spectroscopy, microscopy and polymer testing. New equipment and regular upgrades reflect Chemir’s commitment to customized solutions and scientific excellence.

SEPARATIONSGas Chromatography (GC) Sample Introduction Techniques - Direct Liquid Injection - Static Headspace - Solid Phase Microextraction (SPME) - Purge and Trap - Pyrolysis Detection Systems - Flame Ionization Detection (FID) - Thermal Conductivity Detection (TCD) - Mass Spectrometry (MS)Liquid Chromatography (LC) Detection Systems - Spectrophotometric (UV-Vis) - Refractive Index (RI) - Evaporative Light Scattering (ELSD) - Electrospray Ionization-Ion Trap Mass Spectrometry (ESI-IT-MS) - Atmospheric Pressure Chemical Ionization- Ion Trap Mass Spectrometry (APCI-IT-MS)Gel Permeation Chromatography (GPC)Ion Chromatography (IC)

MOLECULAR SPECTROSCOPYUltraviolet-Visible Spectrophotometry (UV-Vis)Fourier Transform Infrared Spectroscopy (FTIR)Raman SpectroscopyNuclear Magnetic Resonance Spectroscopy (NMR) - Proton 400 MHz - Carbon 400 MHz - Multi Nuclear, 19F, 29Si, 31P, 15N, etc. - Variable Temperature Capabilities - 2D NMR (COSY, NOESY, HMQC, HMBC, TOCSY, HSQC)

ATOMIC SPECTROSCOPYInductively Coupled Plasma/Optical Emission Spectroscopy (ICP/OES)Flame Atomic Emission Spectroscopy (Flame AES)Cold Vapor Atomic Absorption (CVAA)

MICROSCOPY AND SURFACE ANALYSISOptical MicroscopyScanning Electron Microscopy/Energy Dispersive X-ray Analysis (SEM/EDXA)Fourier Transform Infrared (FTIR) - Microscopy - Horizontal Attenuated Total Reflectance (HATR)Raman Microscopy

PHYSICAL AND THERMAL TESTINGInstron 1122/1125Melt Flow IndexThermogravimetric Analysis (TGA)Differential Scanning Calorimetry (DSC)Modulated DSC (MDSC)Dynamic Mechanical Analysis (DMA)

WET CHEMICAL TECHNIQUES AND OTHER EQUIPMENTKarl Fischer Volumetric TitrationpHIon Selective Electrodes (ISE)Soxhlet ExtractionAccelerated Solvent ExtractionGlass Capillary ViscometersBrookfield ViscometersWeathering ChambersZeta PotentialStability Chambers

Additionally, we have access to unique instrumentation at local universities and affiliate facilities. When needed, we partner with outside laboratories that have successfully passed our rigorous quality approval process.

Chemir has helped over 7,000 customers worldwide since 1959.O U R C U S T O M E R S

PARTIAL CLIENT LIST

- 3M Corporation- ACH Food Companies- Akin Gump Strauss Hauer & Feld LLP- AKZO Nobel-Fortafil Fibers, Inc.- Alpha Plastics, Inc.- Anheuser-Busch Companies- Archbald & Spray LLP- Ashland Chemical- BASF Corporation- BF Goodrich Company- Borg-Warner Automotive- Bostik, Inc.- BP Chemicals, Inc.- Calgon Vestal Laboratories- Cargill, Inc.- Chevron Chemical- Colorite Plastics Company- Cozen O’Connor- Da/Pro Rubber Inc.- Dow Chemical Company

- Dowell Schlumberger, Inc.- Dupont- Duracell, Inc.- Eaton Corporation- Emerson Electric- Exxon Chemical Company- FedEx- FMC Corporation- GE Plastics- GenCorp Polymer Products- General Polymers- Georgia-Pacific Corporation- Gillette Company- Graphic Packaging International, Inc.- Gulf States Asphalt Co., Inc.- HB Fuller Company- Holland & Knight LLP- Jones & Granger- Jones Day- Latham & Watkins LLP- MacDermid, Inc.- Mattel Toys, Inc.- MEMC Electronic Materials, Inc.- Monsanto- Morton International- Owens-Corning- Perkin-Elmer- Pillsbury Company- PQ Corporation- Pratt & Whitney- Ralston Purina Company- Rubbermaid Commercial Products- Sonnenschein Nath & Rosenthal- Therm-O-Disc, Inc.- Ultradent Products, Incorporated- United States Army Research Lab- Valspar Corporation- Velcro- W.R. Grace & Company- Zoltek Corporation


Partial Client List - What Customers Say About Chemir -

WHAT CUSTOMERS SAY ABOUT CHEMIR “Responsive, timely and good service.”Kaj Johnson, Method, San Francisco, CA

“Great customer and technical service staff. Very knowledgeable and friendly. Enjoyed collaborating with all Chemir staff.”Marco Hobi, Devro Inc., Columbia, SC “Answers! Several techniques used to get them. Good reports. Thoroughness in analysis.”Dr. Carolyn M. Primus, Primus Consulting, Bradenton, FL

“Exceptional service. Results delivered promptly and always on or before the promised date...very professional and a pleasure to work with.”Dr. Vikram Mehrotra, Monsanto, St. Louis, MO

“The staff was very helpful and the communication was great.”Burk Lattimore, Meadow Gold Dairies, Las Vegas, NV

“Friendly service, well-organized reports, quality results, overall great experience.”Robert Sorenson, Ultradent Products, South Jordan, UT

“Customer service. The quality of work was outstanding!”Timothy Jackson, Jr., FedEx, Memphis, TN

“Excellent follow-up. After analysis was complete, they called me to discuss findings. Good personal touch.”Mark Magnussen, International Paper, Shelbyville, IL “Everything was professionally handled. The analysis was impressive”Robert C. Naylor, Jr., Pierre Foods, Cincinnati, OH “Communication was excellent. It was never a problem to get an update or an explanation. The testing was done in a timely manner, as well as the final report.”Beth Gramza, Beiersdorf, Inc., Cincinnati, OH “Timely, professional, satisfying and informative”Randy Allen, Temple Inland, Humboldt Industrial Park, PA

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“Exceptional service. Results delivered promptly

and always on or before the promised date.”

Recent success stories illustrate Chemir’s experience and capabilities.C A S ES T U D I E S

LEACHING FOOD PACKAGING

A frozen food manufacturer came to Chemir to determine if their “in-the-bag-cooking” packaging was contaminating the food during microwave cooking. Our expert scientists first analyzed the packaging and then the microwaved food samples. Two components from the packaging were found to migrate into the food tested. One served as a flame retardant and the second as a plasticizer. We then helped the client find a new packaging source that did not exhibit leaching, allowing them to resume production.

HEAT SEAL ADHESIVE FAILURE ANALYSIS

Our client’s new heat seal adhesive was not providing a hermetic seal and released after only a few days. Faced with production line shut-down and delayed shipments, the customer called Chemir. They suspected that the new adhesive’s formula, a polyurethane-acrylic hot melt adhesive, was the reason for the failure. Our expert chemists deformulated both the old formula and the new formula. The results showed significant differences in the molecular weight and molecular weight distribution, as well as the urethane-acrylic ratio. After concluding that these variations were the reason for the adhesion failure, we recommended a formula adjustment. The revised formula performed well, and the customer was able to resume operations.

LITIGATION SUPPORT FOR A MANUFACTURER

In a lawsuit against a glass-laminate manufacturer, an installation contractor claimed that an incorrect product formulation was the cause of product failure. The glass-polyester laminates had experienced serious discoloration, degradation, delamination and hydrolysis. Our expert chemists performed a comparative analysis of a failed sample alongside a control sample. From the data, our scientists concluded that the manufacturer used an incompatible UV stabilizer along with an unstable polymer formulation. Chemir scientists presented this data and interpretations as expert witness testimony for the installation contractor, resulting in a positive outcome for our client.

EMERGENCY CONTAMINANT ANALYSIS

Chemir’s 24 hour emergency phone number was called on a Sunday afternoon. The door to a meat processing plant was left open while a pesticide was being sprayed, and they needed to determine if the product was contaminated. Results were needed by the following morning, as 2000 butchers were holding operations. After extracting the meat using a proprietary solvent, Chemir used GC/MS to screen the extracts, looking for the 3 main components of the pesticide. None were observed. We also intentionally spiked samples of meat with pesticide, confirming the effectiveness of the test methods. The processor was able to resume operations on Monday morning.

MEDICAL PLASTIC STABILITY

A manufacturer of an implantable medical device needed to characterize several different polymers in order to identify the materials’ chemical changes over time. The manufacturer needed to know that the device would remain stable and effective inside patient’s bodies. Chemir’s scientists performed GPC analysis comparing the molecular weight of the polymers under various conditions, and were able to recommend an appropriate material selection.


T E R M S A N DC O N D I T I O N S

SERVICES 1. Client acknowledges that Chemir Analytical Services,

Inc. and/or its affiliates (together, “Chemir”) performs analysis and testing services (the “Services”) only as specified in writing by Client. Chemir does not design, warrant, supervise or monitor compliance of products or services except as specifically agreed to in writing prior to the performance of the Services. Client acknowledges that, by their very nature, the Services are limited in scope and subject to expected measurement variability.

2. Samples and portions thereof not destroyed in the performance of the Services remain the property of the Client, are retained a maximum of 30 days after project completion, unless instructed otherwise in writing by Client, and thereafter will be disposed of or returned to Client, at Client’s expense. A sample storage fee of $200.00 per month will be applied on requests for storage past 30 days after project completion.

3. Unless otherwise specified therein in writing, nothing contained in any report issued by Chemir shall be deemed to imply or mean that Chemir conducts any quality control program for the Client to whom the report is issued.

4. Reports issued by Chemir are for the exclusive use of the Client to whom they are addressed. Reports and the name Chemir, or its seals or insignias, are not to be used by or on behalf of Client under any circumstances for any purpose whatsoever, including but not limited to use in advertising, publicity material or in any other manner without Chemir’s prior written approval.

5. Reports issued by Chemir apply only to the standards or procedures identified therein and to the sample(s) tested.

6. Chemir shall retain copies of reports for a period of five years, after which such reports will be destroyed.

7. Unless specified in a report in writing, the analysis and testing results are not indicative or representative of the qualities of the lot from which the sample was taken or of apparently identical or similar products.

8. Deformulation analysis of commercial products is provided for informational purposes only. Chemir strongly recommends review of state and federal laws, trademarks, copyrights and patent situations by the Client prior to use of such information.

9. Chemir reserves the right to subcontract Services to other laboratories. If subcontracting is necessary, samples will be sent only to laboratories meeting Chemir’s qualification requirements.

LIABILITY 1. Chemir is not an insurer or a guarantor. Chemir

represents that the Services shall be performed within the limits mutually agreed to, in writing, and in a manner consistent with the level of care and skill ordinarily exercised by providers of similar services under similar circumstances. No other representations or warranties, express or implied, are included or intended in this agreement, or in any report, opinion or document related to the Services provided hereunder.

2. For the safety of Chemir’s personnel, Client must advise Chemir if samples are known or suspected to contain hazardous substances. Material Safety Data Sheets must be provided if available.

3. Client understands and agrees that Chemir, in entering into this Contract and by performing Services, does not assume, abridge, abrogate or undertake to discharge any duty or responsibility of Client to any other party or parties. No one other than Client shall have any right to rely on any report issued by Chemir. Client agrees, in consideration of Chemir undertaking to perform the Services hereunder, to protect, defend, indemnify, save harmless and exonerate Chemir from any and all claims, damages, including lost profits, expenses, including attorney’s fees, either direct or consequential, for any and all injuries to persons, including the personnel of Chemir, or property arising out of or in consequence of the performance of the Services and/or the performance of the samples tested hereunder.

4. Client agrees that if Chemir should be found liable for any losses or damages attributable to the Services in any respect, Chemir’s liability shall in no event exceed the amount of the fee paid by Client for such Services and Client’s sole remedy at law or in equity shall be the right to recover up to such amount. Client acknowledges and agrees that in no event will Chemir be liable for consequential or incidental damages or expenses, including, but not limited to lost profits.

5. Whenever performance by either party is delayed or prevented by war, insurrection, fire or other casualty, strikes or embargoes, shortage of transportation facilities or any other similar or dissimilar causes, beyond the control of such party, such delay or prevention shall be excused and the time of performance hereunder extended for the duration

of the causative factor.

COSTS AND PAYMENT 1. Client agrees to pay all invoices within 15 days of

invoice date. 2. In the event that payment is not received within 15

days of invoice date, Client agrees to pay a late payment charge on the unpaid balance equal to 1-1/2% per month.

3. All costs associated with compliance with any subpoena(s) for documents, testimony in court of law, or for any other purpose relating to Services performed by Chemir for Client, shall be paid by Client. Client shall also pay Chemir’s then existing standard fees for consulting, deposition and trial testimony and all expenses related thereto.

4. Project specific supplies including, but not limited to, standards, raw materials, shipping, columns and/or specialty chemicals and supplies required for execution of a Client’s project will be purchased by Chemir and billed to Client as pass-through costs. If necessary, Chemir may bill a waste disposal fee of up to 5% of total project cost or $500.00, whichever is lower, to cover proper sample and chemical disposal.

5. Chemir reserves the right to request a prepayment from Client prior to initiating project work.

6. Should Client cancel all or a portion of the project after the project has been initiated, Client will be liable to Chemir for all hours expended on the project up to the time of cancellation, at a rate of $385.00 per hour, plus all project specific supplies at cost, or a minimum of 25% of the estimated project cost as a fee for Chemir’s mobilization on the project, whichever is greater. This cancellation charge is a fee for work performed and is not regarded as liquidated damages.

MISCELLANEOUS 1. This agreement and any and all claims and disputes

hereunder or related thereto shall be governed by the internal laws of the State of Missouri. Chemir and Client agree that exclusive jurisdiction and venue for any and all such claims and disputes shall be in St. Louis County, Missouri.

2. In the event that Chemir prevails in any dispute or claim, including the collection of monies from Client, Client agrees that Client will pay any and all expenses, including collection costs and attorney’s fees, reasonably incurred in the prosecution or defense of such claim, dispute or collection.

3. The terms and conditions contained herein, together with Chemir’s quotation and offer of Services to Client, and Client’s acceptance of such offer, shall constitute the entire agreement between Chemir and Client. Any conflicting terms contained in any order or acceptance submitted by Client shall be null and void.







2672 Me t r o B l v d

Ma r y l a nd He i g h t s , MO 63043

t o l l - f r e e 800 .659 .7659

t e l 314 .291 .6620

f a x 314 .291 .6630

ema i l i n f o@chem i r. c om

web www. c hem i r. c om

Chemir Analytical Services

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