Chapter 6- Cell-cell communication interaction between two or more distinct cells or t _________- the cell of tissue producing the signal __________- the cell or tissue being induced ____ the ability to respond to a given inducer More definitions Pax6 null Wild-type Example - Pax6 is required for optic vesicle to respond to an inducer, but Pax6 is not the inducer Hence, Pax6 makes cells _____________ Fig. 6.2 Lacking nose and eyes
Chapter 6- Cell-cell communication. More definitions. _________ - interaction between two or more distinct cells or tissues. _________ - the cell of tissue producing the signal __________- the cell or tissue being induced. _________ the ability to respond to a given inducer. Fig. 6.2. - PowerPoint PPT Presentation
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Chapter 6- Cell-cell communication
_________-interaction between two or more distinct cells or tissues_________- the cell of tissue producing the signal __________- the cell or tissue being induced
_________ the ability to respond to a given inducer
More definitions
Pax6 nullWild-type
Example- Pax6 is required for optic vesicle to respond to an inducer, but Pax6 is not the inducer
Hence, Pax6 makes cells _____________
Fig. 6.2
Lacking nose and
eyes
1. Instructive vs permissive interactions
_____________ interaction-Tissue A requires tissue B to respond in a certain way (analogy to a book _______________)
____________ interaction-Tissue A does not require tissue B to respond in a certain way, but only needs to be in a certain environment (analogy to a book ______________)
• __________- sheets of cells from any germ layer
• ____________- unconnected cells (from mesoderm or neural crest)
• All organs have both of these cell types
Epithelial-mesenchymal interactions
Epithelial-mesenchymal interactions
_______specificity
________specificity
Wing
Foot
Thigh
Mesen-chyme
Wing epithelium
Thus, mesenchyme __________ epithelium
Fig. 6.7
Epithelial-mesenchymal interactions
Epithelial-mesenchymal interactions
Regional specificity
_______specificity
Frog gastrula
Newt gastrula
Newt gastrula
Frog gastrula
Thus, mesenchyme dictates _______ type, but epithelium dictates ____ of the organ
Newt with tadpole suckers
Frog with newt “balancers”
Paracrine factors__________factors- diffusible molecules that can travel small distances to signal a neighboring cell__________signaling- cell-cell interactions by direct contact