Chapter 11 (part 2) Regulation of Glycolysis. Lactate formation.

Chapter 11 (part 2)

Regulation of Glycolysis

Lactate formation

H3C C C

OO

O

NADH NAD

NADH NAD

H3C CH

C

OHO

O

Cori Cycle

Alcohol Fermentation

Free Energy Change in Glycolysis

HexokinasePhosphofructokinase-1

Pyruvate kinase

Control Points in Glycolysis

Insulin Induced Exocytosis of Glucose Transporter

Effect of ATP on PFK-1 Activity

Effect of ADP and AMP on PFK-1 Activity

Regulation of PFK by Fructose-2,6-bisphosphate

Glucagon Regulation of PFK-1 in Liver

Pyruvate Kinase Regulation

Other Sugars can

enter glycolysis