CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences.

CERVICAL/VAGINAL CYTOLOGY

N. Shayanfar MD

Associate Professor of Pathology

Tehran University of Medical Sciences

INTRODUCTION&HISTORY

Dr.George N.Papanicolaou(1883-1962) Dr.Aurel A.Babes 1927 Dr.George Papanicolaou&Dr.Herbert

F.Traut 1943

Microscopic Anatomy

Vagina:Non-Keratinizing Stratified Squamous Cervix:

Ectocervix:Non-Keratinizing Stratified Sqamous

Endocervix:Tall Columnar Epithelium �ُSquamocolumnar Junction

Original

Transformation zone

ASSESSMENT OF QUALITY OF SMEARS

THE BETHESDA SYSTEM

Statement of specimen adequacy Epithelial cell abnormalities Others

ADEQUACY OF THE SPECIMEN

Satisfactory for evaluation

Unsatisfactory

Epithelial cell abnormalities

Low grade intraepithelial lesion(LSIL)

-CIN1(mild dysplasia) & HPV changes High grade intraepithelial lesion

-CIN2,CIN3,CIS(carcinoma insitu)

LSIL

LSIL,HPV changes

HSIL