C 1800’s 1859 : Darwin proposin 1865 : Mendele 1869 : DNA Fis 1879 : Mitosis O 1900’s 1900 : Rediscov 1902 : Orderly 1902 : Chromos 1909 : The wor 1911 : Fruit File 1940’s 1941 : One Gen 1943 : X-ray Di 1944 : DNA is “ 1944 : Jumping CELL – TIME LINE publishes On the origin of Spe ng continual evolution of species. e’s peas st Isolated Observed very of Mendel’s work Inheritance of Disease Observed some Theory of Heredity rd Gene Coined es Illuminate the Chromosome Theory ne, One Enzyme iffraction of DNA “Transforming Principle” g Genes ecies,
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Transcript
CELL
1800’s
1859 : Darwin publishes On the origin of Species,
proposing continual evolution of species.
1865 : Mendele’s peas
1869 : DNA Fist Isolated
1879 : Mitosis Observed
1900’s
1900 : Rediscovery of Mendel’s work
1902 : Orderly
1902 : Chromosome Theory of Heredity
1909 : The word Gene Coined
1911 : Fruit Files Illuminate the
1940’s
1941 : One Gene, One Enzyme
1943 : X-ray Diffraction of DNA
1944 : DNA is “Transforming Principle”
1944 : Jumping Genes
CELL – TIME LINE
Darwin publishes On the origin of Species,
proposing continual evolution of species.
Mendele’s peas
DNA Fist Isolated
Mitosis Observed
Rediscovery of Mendel’s work
Orderly Inheritance of Disease Observed
Chromosome Theory of Heredity
The word Gene Coined
Fruit Files Illuminate the Chromosome Theory
One Gene, One Enzyme
ray Diffraction of DNA
DNA is “Transforming Principle”
Jumping Genes
Darwin publishes On the origin of Species,
1950’s
1952 : Genes are Made of DNA 1953 : DNA Double Helix
1955 : 46 Human Chromosomes
1955 : DNA Copying Enzyme
1956 : Cause of Disease Traced to Alternation
1958 : Semiconservative Replication of DNA
1959 : Chromosome Abnormalities Identified
1960’s
1961 : mRNA Ferries Information 1961 : First Screen for Metabolic Defect in Newborns
1966 : Genetic Code Cracked
1968 : First Restriction Enzymes Described
1970’s
1972 : First Recombinant DNA 1973 : First Animal Gene cloned
1975 -77: DNA Sequencing
1976 : First Genetic Engineering Company
1977 : Introns Discovered
1980’s
1981-82 : First Transgenic Mice and Fruit Files
1982 : GenBank Dateabase Formed
1983 : First Disease Gene Mapped
1983 : PCR Invented
1986 : First Time Gene Positionally Cloned
1987 : First Human Genetic Map
1987 : YACs Developed
1989 : Microsatellites, New Genetic Markers
1989 : Sequence-tagged Sites, Another Marker
1990 – 1994
1990 : Launch of Human Genome Project
1990 : ELSI founded
1990 : Research on BACs
1991 : ESTs, Fragments of Genes 1992 : Second-generation Genetic Map of Human Genome