20/02/2017 1 Cardiovascular health & Health Promotion HH2602 & HH5607 Lecture 2: Microscopic Structure and Function of the Heart 2pm 28-02-17 ESGW Teaching Aims To introduce you to the micro- structure of heart muscle. To highlight the link between cardiac structure and cardiac function Learning Out-comes: At the end of the session you will be able to: Outline the structure of cardiac muscle Identify the unique functions and properties of heart cells, and link structure to function.
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Cardiovascular health & Health Promotion HH2602 & … · 2017-02-21 · Cardiovascular health & Health Promotion HH2602 & HH5607 Lecture 2: ... Cardiac mm = myogenic auto-rhythmicity
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20/02/2017
1
Cardiovascular health &Health Promotion HH2602
& HH5607
Lecture 2: MicroscopicStructure and Function of
the Heart
2pm 28-02-17 ESGW
Teaching Aims
To introduce you to the micro-structure of heart muscle.
To highlight the link between cardiacstructure and cardiac function
Learning Out-comes:
At the end of the session you will beable to:
Outline the structure of cardiac muscle
Identify the unique functions andproperties of heart cells, and linkstructure to function.
20/02/2017
2
The Myocardium:
Consists of 3 types of excitable cells
1. myocardial cells +++
2. pace-maker cells
3. cells of the intrinsic cardiacconducting system
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Figure 18.8 a, b
Cardiac cytoskeleton :
Function of cardiac cytoskeleton:
1. Orientates muscle fibres
2. Acts as a tendon
2. Re-enforces vessel entry / exit points
3. Re-enforces valves
4. Forms a non- excitable zone between atria& ventricles – to safe-guard the independentelectrical and mechanical activity of the 2“hemispheres”
Cardiac cytoskeleton :
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The innervation of the heart:
SNS – muscle fibres generally espVentricular fibres, PM cells, cells of theintrinsic conducting system – all via β1