Carbamazepine Carbamazepine is a drug that is licensed to treat several conditions, including bipolar disorder, epilepsy, and trigeminal neuralgia. The prescription medication is available in a number of forms, including tablets, chewable tablets, extended-release tablets, extended-release capsules, and suspension (liquid). Depending on the product, carbamazepine is usually taken two to four times daily. As with any drug, there are possible side effects with carbamazepine, such as dizziness, drowsiness, and nausea. Carbamazepine Medication Information • Carbamazepine • Carbamazepine Side Effects • Carbamazepine and Hair Loss • Carbamazepine and Dry Mouth • Carbamazepine Uses • Carbamazepine Dosage • Carbamazepine Drug Interactions • Carbamazepine Warnings and Precautions • Carbamazepine Overdose • Carbamazepine and Pregnancy • Carbamazepine and Breastfeeding • Carbamazepine Withdrawal Scroll up Scroll down What Is Carbamazepine? Carbamazepine (Carbatrol ® , Epitol ® , Equetro ® , Tegretol ® ) is a prescription medication used to treat the following conditions: • Bipolar disorder-- carbamazepine is approved to treat manic or mixed episodes (which include characteristics of both mania anddepression) associated withbipolardisorder, also known as manic depression. • Epilepsy -- carbamazepine is approved to treat varioustypes of seizures, though it is usually not effective at treating absence seizures (petit mal seizures).
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• Trigeminal neuralgia -- carbamazepine is approved to treat pain associated
with trigeminal neuralgia (also known as tic douloureux), a nerve condition
that causes episodes of facial pain (typically cheek or jaw pain).
Not all forms of carbamazepine are approved for each of the above uses. Equetro is
approved to treat bipolar disorder only, while Carbatrol, Epitol, Tegretol, and generic
carbamazepine are approved to treat epilepsy and trigeminal neuralgia (but not bipolar
disorder).
How Does Carbamazepine Work?
Epilepsy is a brain disorder that causes recurring, brief changes in how the brain's
electrical system works. These changes in brain activity can lead to a seizure (see Epilepsy Symptoms ). It is not known exactly how carbamazepine works to prevent
partial seizures in people with epilepsy. It may work by blocking sodium channels in
the brain. By blocking sodium channels, carbamazepine may decrease the activity of
nerve cells, preventing them from firing abnormally. Carbamazepine may also prevent
the abnormal brain signals from spreading to other parts of the brain.
It is thought that carbamazepine works to treat trigeminal neuralgia by blocking the
nerve signals that cause pain and other unpleasant sensations.
It is not known exactly how Equetro works for bipolar disorder treatment. Equetro
affects several different brain chemicals -- though it is not known if this is howEquetro works to treat bipolar disorder .
When and How to Take Carbamazepine
Some general considerations for when and how to take carbamazepine include:
• Carbamazepine comes in several different forms, including tablets, chewable
tablets, extended-release tablets, extended-release capsules, and suspension
(liquid). It is taken by mouth, usually two to four times daily, depending onthe particular product.
• Carbamazepine can be taken with or without food. If carbamazepine upsets
your stomach, try taking it with food.
• Carbamazepine suspension -- make sure to shake the suspension thoroughly
just before each dose. Do not mix the suspension with food or other liquids(including other medications).
It is possible that you may experience some or none of the carbamazepine side effects
listed in this article. Unfortunately, there is no way for your healthcare provider to
know beforehand if you will have side effects from a medicine that you have never
tried. Therefore, make sure to let your healthcare provider know if you develop any
side effects while taking carbamazepine. Also let your healthcare provider know if
you develop something that "just does not seem right." While it may not be a sideeffect of carbamazepine, your healthcare provider will be able to diagnose and treat
the problem.
Carbamazepine Uses
Carbamazepine is used for treating various types of epileptic seizures,
pain associated with trigeminal neuralgia (a painful nerve
disorder), and manic or mixed episodes associated with bipolar
disorder. The medication is approved for treating epilepsy in
children, but it is not approved for treating bipolar disorder or
trigeminal neuralgia in children. Off-label carbamazepine uses
can include the treatment of dementia, alcohol withdrawal, and
hiccups.
Carbamazepine Medication Information
• Carbamazepine
• Carbamazepine Side Effects
• Carbamazepine and Hair Loss
• Carbamazepine and Dry Mouth
• Carbamazepine Uses
• Carbamazepine Dosage
• Carbamazepine Drug Interactions
• Carbamazepine Warnings and Precautions
• Carbamazepine Overdose• Carbamazepine and Pregnancy
• Carbamazepine and Breastfeeding
• Carbamazepine Withdrawal
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What Is Carbamazepine Used For? -- An Overview
Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®) is a prescription medicationused to treat the following conditions:
Bipolar disorder , also known as manic depression, is a serious brain disease that
causes extreme shifts in mood, energy, and functioning. Currently, it is thought that
bipolar disorder may be at least partially genetic (see Bipolar Causes ). Bipolar
disorder is different from the normal ups and downs that everyone goes through -- the
symptoms of bipolar disorder are more severe. Episodes of mania and depression
typically recur throughout the affected person's lifespan.
Between episodes, most people with bipolar disorder are free of symptoms (see
Bipolar Disorder Symptoms ). Effective bipolar disorder treatment usually involves a
combination of psychotherapy (see Bipolar Psychosocial Treatments ) and bipolar
medications.
One brand of carbamazepine (Equetro) is approved to treat manic or mixed episodes
associated with bipolar disorder. Mixed episodes have characteristics of both mania
and depression. Equetro has not been adequately studied for the long-term treatment
of bipolar disorder.
Carbamazepine and Epilepsy
Epilepsy is a brain condition that occurs when there are sudden, brief changes in how
the brain's electrical system works. These changes in brain activity can lead to a
seizure (see Epilepsy Symptoms ). Depending on which part of the brain is affected, a
seizure may affect the person's consciousness, body movements, emotions, or senses
(taste, touch, smell, vision, or hearing).
Some people may only have a single seizure during their lives, and one seizure doesnot mean that a person has epilepsy (see Seizures and Epilepsy ). In fact, the term
epilepsy refers to a number of different kinds of unprovoked, recurring seizures that
happen for a number of different reasons.
In over half of all cases, the cause of epilepsy is not known. There are over 30
different types of seizures a person with epilepsy may experience. These seizures are
generally classified into two main categories, partial seizures (also known as focal
seizures) and generalized seizures.
Epilepsy treatments may include medications (see Epilepsy Medication ), surgery (see
Epilepsy Surgery ), diet changes (see Epilepsy Diet ), and biofeedback. Carbamazepineis approved to treat various types of seizures, including:
• Partial seizures, including simplex partial or complex partial seizures
• Generalized seizures, including generalized tonic-clonic seizures (grand-mal
seizures)
• Mixed seizures.
Carbamazepine is generally not considered effective at treating absence seizures (alsoknown as petit mal seizures).
Epilepsy is a brain disorder that causes recurring, brief changes in how the brain's
electrical system works. These changes in brain activity can lead to a seizure (see
Epilepsy Symptoms ). It is not known exactly how carbamazepine works to prevent
partial seizures in people with epilepsy. It may work by blocking sodium channels in
the brain. By blocking sodium channels, carbamazepine may decrease the activity of
nerve cells, preventing them from firing abnormally. Carbamazepine may also prevent
the abnormal brain signals from spreading to other parts of the brain.
It is thought that carbamazepine works to treat trigeminal neuralgia by blocking the
nerve signals that cause pain and other unpleasant sensations.
It is not known how exactly carbamazepine works for bipolar disorder treatment.Carbamazepine affects several different brain chemicals, though it is not known if this
is how carbamazepine works to treat bipolar disorde
Carbamazepine Uses (Cont.)
Carbamazepine Medication Information
• Carbamazepine
• Carbamazepine Side Effects
• Carbamazepine and Hair Loss
• Carbamazepine and Dry Mouth
• Carbamazepine Uses
• Carbamazepine Dosage
• Carbamazepine Drug Interactions
•
Carbamazepine Warnings and Precautions• Carbamazepine Overdose
• Carbamazepine and Pregnancy
• Carbamazepine and Breastfeeding
• Carbamazepine Withdrawal
Scroll up Scroll down
Carbamazepine Uses in Children
Carbamazepine is approved for epilepsy treatment in children. It is not approved for
treating bipolar disorder or trigeminal neuralgia in children. Talk with your healthcare
provider about the benefits and risks of using carbamazepine in children.
The dose of carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®) that your
healthcare provider recommends will vary depending on a number of factors,
including:
• Your age and weight
• The condition being treated
• The particular carbamazepine product
• Other medications you may be taking
• Other medical conditions you may have.
As always, do not adjust your carbamazepine dose unless your healthcare provider
specifically instructs you to do so.
(Click on the following links for dosing information for your particular
carbamazepine product:
• Carbatrol Dosage
• Epitol Dosage
• Equetro Dosage
• Tegretol Dosage , which also applies to generic carbamazepine tablets and suspension.)
General Carbamazepine Dosage Information
Some considerations for people taking carbamazepine include:
• Carbamazepine comes in several different forms, including tablets, chewable
tablets, extended-release tablets, extended-release capsules, and suspension(liquid). It is taken by mouth, usually two to four times daily, depending on
the particular product.
• Carbamazepine can be taken with or without food. If carbamazepine upsets
Generally, you should not drink alcohol if you are taking carbamazepine. Doing so
may increase your risk of side effects.
AntidepressantsSome antidepressants can raise the level of carbamazepine in your blood, increasing
your risk of carbamazepine side effects. Also, carbamazepine can decrease the level
of some antidepressants in your blood, perhaps making them less effective. Talk with
your healthcare provider before combining an antidepressant with carbamazepine.
Certain Antibiotics or Antifungals
Some antibiotics and antifungal medications can raise the level of carbamazepine in
your blood, increasing your risk of side effects. Additionally, carbamazepine can
make some antifungal medications less effective. Talk with your healthcare provider
before using these medications together.
Certain Antipsychotic Medications
Carbamazepine can decrease the levels of some antipsychotic medications in your
blood, making them less effective. If you are taking these drugs together, your
healthcare provider may need to increase your antipsychotic medication dose.
Calcium Channel Blockers
Some calcium channel blockers can raise the level of carbamazepine in your blood,
increasing your risk of carbamazepine side effects. Also, carbamazepine can decrease
the levels of some calcium channel blockers in your blood, perhaps making them less
effective. Talk with your healthcare provider before combining a calcium channel
blocker with carbamazepine.
Cisplatin (Platinol)
Cisplatin can decrease the level of carbamazepine in your blood, perhaps making it
less effective. If you are taking these drugs together, your healthcare provider may
need to monitor the level of carbamazepine in your blood and adjust your
carbamazepine dosage as necessary.
Cimetidine (Tagamet)
Cimetidine can raise the level of carbamazepine in your blood, increasing your risk of
side effects. In general, you should not take these medications together, as there aremany other cimetidine alternatives that do not interact with carbamazepine.
Cyclosporine (Gengraf, Neoral, Sandimmune)
Carbamazepine can decrease the level of cyclosporine in your blood, perhaps making
it less effective. If you are taking these drugs together, your healthcare provider may
need to increase your cyclosporine dosage.
Danazol (Danocrine)
Danazol can raise the level of carbamazepine in your blood, increasing your risk of
side effects. If you are taking these drugs together, your healthcare provider may need
to monitor the level of carbamazepine in your blood and adjust your carbamazepinedosage as necessary.
Taking theophylline with carbamazepine can decrease the levels of both medicationsin your blood, making them less effective. Talk with your healthcare provider before
taking these medications together.
Final Thoughts on Carbamazepine Drug Interactions
It is possible that not all carbamazepine drug interactions were discussed in this
article. Therefore, you should talk with your pharmacist or healthcare provider about
any specific drug interactions with carbamazepine that may apply to you.
Carbamazepine Warnings and
Precautions
Some carbamazepine warnings and precautions to be aware of include
potential drug interactions, the safety of taking carbamazepine
while nursing or pregnant, and people who should not take
carbamazepine at all. Among the conditions that you should tell
your healthcare provider about prior to taking the drug are heartdisease, thyroid problems, and glaucoma. Among the people who
should not take carbamazepine are those who have had bone
marrow depression and those who are allergic to tricyclic
Phenobarbital, a barbiturate, is used as a sleep aid and in the treatment of certain typesof epilepsy, including generalized or grand mal seizures and partial seizures.
Most important fact about Phenobarbital
Phenobarbital can be habit-forming. You may become tolerant (needing more and
more of the drug to achieve the same effect) and physically and psychologically
dependent with continued use. Never increase the amount of phenobarbital you take
without checking with your doctor.
How should you take Phenobarbital?
Take Phenobarbital exactly as prescribed.
If you are taking phenobarbital for seizures, do not discontinue it abruptly.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for your next dose, skip the one
you missed and go back to your regular schedule. Never take 2 doses at once.
--Storage instructions...
Store at room temperature in a tightly closed container.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, notify your
doctor as soon as possible. Only your doctor can determine whether it is safe for you
Other epilepsy drugs such as Dilantin, Depakene, and Depakote
Other sedatives such as Nembutal and Seconal
Steroids such as Medrol and Deltasone
Tranquilizers such as Xanax and Valium
Special information if you are pregnant or
breastfeeding
Barbiturates such as phenobarbital may cause damage to the developing baby during
pregnancy. Withdrawal symptoms may occur in an infant whose mother took
barbiturates during the last 3 months of pregnancy. If you are pregnant or plan to
become pregnant, inform your doctor immediately.
Phenobarbital appears in breast milk and could affect a nursing infant. If phenobarbital is essential to your health, your doctor may advise you to stop
breastfeeding until your treatment is finished.
Recommended dosage
ADULTS
Sedation
The usual initial dose of phenobarbital is a single dose of 30 to 120 milligrams. Your doctor may repeat this dose at intervals, depending on how you respond to
Phenobarbital.
You should not take more than 400 milligrams during a 24-hour period.
Daytime Sedation
The usual dose is 30 to 120 milligrams a day, divided into 2 to 3 doses.
To Induce Sleep
The usual dose is 100 to 200 milligrams.
Anticonvulsant Use
Phenobarbital dosage must be individualized on the basis of specific laboratory tests.
Your doctor will determine the exact dose best for you. The usual dose is 60 to 200