Cancer MITOSIS GONE WILD!. Cells division is … The multiplying of cells through mitosis resulting in generation after generation of identical daughter.

CancerCancer

MITOSIS GONE WILD!

Cells division is …Cells division is …

• The multiplying of cells through mitosis resulting in generation after generation of identical daughter cells. The daughter cells receive exact copies of the parent cell’s DNA.

Why do we need cell division?Why do we need cell division?

1. Allows us to grow

2. Allows us to heal and repair ourselves

3. Even allows us to reproduce

The Reasons for Cancer The Reasons for Cancer

• Cancer occurs when:– the rate of cell division goes out of control.– Mutations occur in the genes that control cell

division.

• Mutations are cells with changes to their DNA.

• A Carcinogen is any chemical or energy that causes a mutation in DNA.

The Reasons for Cancer The Reasons for Cancer

• Cancer cells reproduce in defiance of the normal restraints:

‒ They don’t stop at the checkpoints in the cell cycle

‒ They lack cell-to-cell communication ability

‒ They resist to cell “suicide” signals

Images of CancerImages of Cancer

• The following slides include images of advanced stages of different cancers.

• The images may be somewhat disturbing, so if you are squeamishsqueamish, you may want to cover your eyes.

Skin CancerSkin Cancer

Lung CancerLung Cancer

Brain CancerBrain Cancer

Oral CancerOral Cancer

Tumor on SpleenTumor on Spleen

Causes for Cancerous MutationsCauses for Cancerous Mutations

1. Viruses - some viruses interfere with cell division by inserting their own DNA

2. Radiation - high energy radiation like ultraviolet light, X-rays and Gamma rays have been linked to forms of cancer

3. Chemicals - cigarette smoke and smog have been linked to lung cancer

Tumour TermsTumour Terms

• A tumour is a mass of disfunctional cells that have a grown from mutant parents.

1. Benign tumours: mainly harmless– Cells remain clustered together.

2. Malignant tumours: can be deadly. – Parts of these tumors can break off and

spread throughout your body (metastasis).

Cancer TreatmentsCancer Treatments

1. Surgery: tumour is cut out.

2. Radiation Therapy: radiation is used to kill the tumour cells

3. Chemo Therapy: Toxic chemicals attempt to poison the cancer cells (stop mitosis).

Or a combination of all 3.

Reflect On Your LearningReflect On Your Learning

• Produce a K-Q-L chart for this lesson in your notes.

KNEW QUESTIONS LEARNED

Identify 2-3 things from the lesson that you already knew

Identify 2-3 questions that you now have about the lesson

Identify 2-3 things that you learned about during the lesson