16-11-15 1 International Society of Chemotherapy for Infection and Cancer www.ischemo.org
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International Society of Chemotherapy for Infection and Cancer
www.ischemo.org
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PeoplewhosaythatzeroHAIsarepossible…¤ RedefinedHAIs
² CLABSI=2setsofbloodculturesandFpwithgenoFpicallyidenFcalpathogenandbloodculturedrawn(notviathecatheter)negaFve
¤ UsemeanstaFsFcalmethodse.g.“median”¤ PeoplewhohaveneverseenahospitalfromtheinsideandmakewildassumpFons
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Swisscheeseaccidentmodel
Swisscheeseaccidentmodel
Handhygiene
AnFbioFcmisuse
Lackingskills
Understaffing
Crosstransmission
Badluck
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Handhygiene
AnFbioFcmisuse
Lackingskills
Understaffing
Crosstransmission
Badluck
NI
outbreak
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BIG-FAT
Guide
line
EvenbeUerGuideline
VerylongsuperGuideline
LocalRecommendaFon
NaF
onalRecom
men
daFo
n
TinyoverlookedGuideline
RecommendaFon
MoreRecom
mendaFon
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Fasces=bundle=strength
¤ AbundleisastructuredwayofimprovingtheprocessesofcareandpaFentoutcome
² asmallsetofevidence-basedpracFces² generallythreetofive² performedcollecFvelyandreliably
¤ ProventoimprovepaFentoutcomes
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² Evidencebased
² AchievableinallpaFents
² Covertherelevantaspectsoftheprocedure
Evidencebased
Coverrelevan
taspects
Achievab
leinallpa
?ents
¤ Createacultureofsafety¤ CreateamulF-disciplinaryimprovementteam¤ Ensurefullcommitmentwiththebundleelements² NomorediscussionsabouttheeffecFvenessofthebundleelementsoncestarted
¤ Agreeuponthelengthoftheimprovementperiodandlevelofadherencewithmeasures² IfthatisnotpossibleàDon’tstart!
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1 2 3 4 5 6 7 8 Elementcompliance
Element1 Y Y N Y Y Y Y Y 87.5%
Element2 Y N Y N Y Y Y Y 75%
Element3 N Y Y Y Y Y N Y 75%
Element4 Y Y Y Y Y N Y Y 87.5%
Element5 Y Y Y Y Y Y Y N 87.5%
PaFents/procedures
BundleCompliance 12.5%
Surgical Site Infections
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Noinfluencepossible
¤ Age
¤ Underlyingdisease
¤ Malignancy
¤ WoundclassificaFon
¤ ProstheFcmaterial
Influence not probable • Laminarair-flow• SterilizaFon• Pre-op hospitalization
Influence by others
• BMI >30
• Nicotine use
• Malnutrition
• Infection at remote site
Can & should be influenced
• Surveillance
• S. aureus colonization
• Normothermia/hyperoxia
• Glucose levels
• Hair-removal
• Antimicrobial prophylaxis
• Skin disinfection/decolonization
¤ Hairremoval
¤ AnFmicrobialprophylaxis
¤ Normothermia
¤ DisciplinintheOR?
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BundleCompliance
SSIRate
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¤ Builtimprovementteam(A-team)
¤ SelectintervenFons¤ Implementinter-venFons
¤ CheckcompliancewithintervenFons
¤ Checkoutcome
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PhamD
ClinMicro/ID
ICT
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¤ Control/restrictuseofreserve-anFbioFcs¤ SelectandmeasureindicatorsforadequateanFmicrobialuse
¤ Standardizeempirictreatmentandfosteriv-oralswitch
¤ EducaFonandtrainingwithregardtoanFmicrobialuse
¤ DefineallpaFentscategoriesthatneedbed-sideIDconsultaFon
Control/restrictuseofreserve-an?bio?cs.¤ An$bio$cguideline¤ ChecksbyA-team¤ Automa$creportsonDDD’sper1000pat-days¤ Pre-useauthoriza$on¤ Restric$verepor$ng
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Selectandmeasureindicatorsforadequatean?microbialuse.¤ Check“useaccordingtoguideline”by
² point-prevalencestudies² dailyconsulta$ons² audits
Standardizeempirictreatmentandfosteriv-oralswitch.¤ On-lineAB-guideline¤ “5xS”aspartofconsulta$on&teaching
² start,safety,streamline,switch,stop
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Educa?onandtrainingwithregardtoan?microbialuse¤ Con$nuouseffortofID&ClinMicro
² ownfellows² partofhospitalfelloweduca$on² partofrounds² “switchoftheweek”
Defineallpa?entscategoriesthatneedbed-sideIDconsulta?on¤ Allpa$entswithmeningi$s,endocardi$s,usingan$bio$csforlongerthan2weeks,sufferinganS.aureusbacteremia,andreceivingreservean$bio$csareseenatbed-sidebyID/CM
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¤ Real-Fmesurveillance(includingfeedback)oflocalresistancetrendsandresistancerelatedproblemsintheregion/country
¤ AnFbioFc/treatmentguidelines¤ InfecFoncontrolguidelines¤ NaFonalorregionalresistancesurveillance¤ NaFonalorregionalHAIsurveillance¤ AnFmicrobialusesurveillance¤ Auditsbasedonprofessionalstandards(IGZ)¤ CM/ICP/IDspecialistsinallmajorhealthcaresenngsandregionalco-operaFon