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Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e- Health Unit) e-Health Unit, University College London Christine Godfrey (Head of Department) Catherine Hewitt (Research Fellow) Dept. Health Sciences, University of York Suzanne Hartley (Senior Trial Coordinator) CTRU, University of Leeds
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Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Jan 04, 2016

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Page 1: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Can stand-alone computer-based interventions reduce alcohol consumption?

Zarnie Khadjesari (PhD student)Elizabeth Murray (Director e-Health Unit)

e-Health Unit, University College London

Christine Godfrey (Head of Department)Catherine Hewitt (Research Fellow)

Dept. Health Sciences, University of York

Suzanne Hartley (Senior Trial Coordinator)CTRU, University of Leeds

Page 2: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Background

•Alcohol misuse is a major public health concern

•Gap between need and access •Internet interventions

– Convenient, confidential, and comparatively low cost– Scalability and personalised approach

•Recent reviews– Elliot 2008 (computer-based interventions for college drinkers)– Bewick 2008 (Internet interventions)– Riper 2009 (personalised feedback interventions – any modality)

Page 3: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Why conduct this review?

•All designs of computer-based intervention

•All computer-based (on- and off-line)

•All adult populations

•Meta-analysis

Page 4: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Aim

• To determine the effectiveness of computer-based interventions aimed at reducing alcohol consumption

• Computer-based interventions compared with either:

i. Minimally active comparator (e.g. assessment-only, information-only website)

ii. Active comparator (e.g. face-to-face motivational interview)

Page 5: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Inclusion criteria

• Study design: RCT• Population: Adults (excl. dependent drinkers)• Intervention:

– Computer-based interventions aimed at reducing alcohol intake– Definition: behavioural interventions, adapted for computer– Stand-alone: no expert facilitation

• Outcome: Alcohol consumption– Grams per week– Frequency of binges / week

Page 6: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Search results

Databases searched from inception – end 2008

MedlineEmbaseWeb of ScienceCochrane LibraryPsycINFOCinahlERICISI ProceedingsIBSSIndex to Theses

10 databases searched 8,084 references

Excluded7,930

Full paper ordered

154

Excluded119

Included publications

36

Individual studies

23

Page 7: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Characteristics of included studies (1)

Year published

1997 = 1; 2004 = 4; 2005 = 3; 2006 = 3; 2007 = 7; 2008 = 5.

Country US = 17; NZ = 3; Netherlands = 1; Germany = 1; UK = 1.

Population •Students = 17 •Problem drinkers from general population = 3•Workplace employees = 2•Emergency department attendees = 1

Page 8: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Characteristics of included studies (2)

Screening •At-risk drinkers = 10•Any drinkers = 6•No-screen = 7

Intervention approach

•Personalised feedback•Harm-prevention / skills training•Expectancy challenge•Self-control / CBT / motivational enhancement

Page 9: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Characteristics of included studies (3)

Comparator Minimally active comparator = 21 Active comparator = 3

Outcome Grams per week = 18Frequency of binges (days or occasions / week) = 8

Page 10: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Results

Comparison: minimally active comparator (n=2,425)Outcome: g/wk

Page 11: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Sub-group analysis - population

Page 12: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Results

Comparison: minimally active comparator (n=848)Outcome: binge frequency / wk

Page 13: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Results

Comparison: active comparator (n=457)Outcome: g/wk

Page 14: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Further analyses

• Skewed data

• Baseline risk

• Loss to follow-up

Page 15: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Summary of findings

• Computer-based interventions appear:– more effective than minimally active comparator– as effective as alternative treatment approaches

• Findings support continued development and evaluation of computer-based interventions for reducing alcohol intake

Page 16: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Limitations of this review

• Restricted to stand-alone interventions

• Different types of computer-based interventions

• Two measures of alcohol consumption

• Mediators of drinking outcomes, s/a motivation, normative perceptions.

• Dose response

Page 17: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Gaps in the literature

• Few comparisons with conventional approaches

• Few studies in non-student adult populations

• Few studies outside the US

• Few studies measuring long-term effectiveness

Page 18: Can stand-alone computer-based interventions reduce alcohol consumption? Zarnie Khadjesari (PhD student) Elizabeth Murray (Director e-Health Unit) e-Health.

Thank you for listeningQuestions, comments, suggestions?