Cambridge Rights Medicine Titles Autumn 2012

Medicine titlesAutumn 2012

For all enquiries on rights titles please contact [email protected]

www.cambridge.org/rights

2 Contents

Anesthesia, intensive care, pain management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3

Emergency psychiatry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12

General medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15

Medical imaging . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16

Medical law, medical ethics, forensic medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

Mental health, psychiatry and clinical psychology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

Neurology and clinical neuroscience . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29

Obstetrics and gynecology, reproductive medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36

Pediatrics and child health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40

Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41


3Anesthesia, intensive care, pain management

Essential Pain PharmacologyThe Prescriber’s Guide

Howard S. SmithAcademic Director of Pain Management

and Marco PappagalloDirector, Pain Management and Medical Mentoring, NY Medical Home for Chronic Pain

DescriptionEssential Pain Pharmacology: The Prescriber’s Guide expertly reviews the most important medications used to relieve pain, now considered by many physicians as the fifth vital sign . The catalogue of analgesics has expanded rapidly, and this text presents the most up-to-date, comprehensive array of agents available for prescribing . Each clear and concise drug entry covers the range of indications, advantages and disadvantages, and tips for appropriate dosing and avoiding adverse effects . A separate section covers nutraceuticals, a class of drug increasingly used to manage chronic pain, yet little discussed in medical literature . The detailed description of each medication enables the user to make quick and informed decisions, confident that they are best serving the needs of their patients . Practical ‘pearls’ for each entry provide a quick go-to reference for the key information to consider before prescribing . This concise user-friendly reference is a must-have on the shelf of every physician .

Key Features

• Aseparatesectioncoversnutraceuticals,aidingbothpatientsself-administeringtheseagentsandphysiciansconsideringtheiruseto manage chronic pain

• ‘Pearlsofwisdom’givequick,practicalhintstoaidconfidentprescribinginrealclinicalsituations

• User-friendly,intuitivelayoutensuresthatkeyclinicalinformationcanbeaccessedrapidlywhentimeisshort

http://www.cambridge.org/gb/knowledge/isbn/item6803170/?site_locale=en_GB


4 Anesthesia, intensive care, pain management

ContentsIntroduction;List of icons;Acetaminophen/Paracetamol;Almotriptan;Amitriptyline;Aspirin;Baclofen;Botox-A;Botox-B;Buprenorphine;Butorphanol;Carbamazepine;Carisoprodol;Celecoxib;Choline magnesium trisalicylate;Citalopram;Clomipramine;Clonazepam;Clonidine;Codeine;Cyclobenzaprine;Cyproheptadine;Dantrolene;Desipramine;Desvenlafaxine;Diazepam;Diclofenac;Diflunisal;Dihydroergotamine;DM;Doxepin;Dronabinol;Duloxetine;Eletriptan;Escitalopram;Etodolac;Fenoprofen;Fentanyl;Flunarizine;Fluoxetine;

Flurbiprofen;Fluvoxamine;Frovatriptan;Gabapentin;Hydrocodone;Hydromorphone;Ibuprofen;Imipramine;Indomethacin;IT ziconotide, epidural clonidine;Ketamine;Ketoprofen;Ketorolac;Lacosamide;Lamotrigine;Levetiracetam;Levorphanol;Lidocaine 5%;Maprotiline;Meclofenamate;Mefenamic acid;Meloxicam;Memantine;Meperidine/Pethidine;Metaxalone;Methadone;Methocarbamol;Methylphenidate;Mexiletine;Milnacipran;Modafanil;Morphine;Nabumetone;Nalbuphine;Naproxen and naproxen sodium;Naratriptan;Nortriptyline;Orphenadrine;Oxaprozin;Oxcarbazepine;Oxycodone;

Oxymorphone;Pamidronate;Paroxetine;Pentazocine;Piroxicam;Pizotifen;Pregabalin;Propranolol;Rizatriptan;Salsalate;Sertraline;Sulindac;Sumatriptan;Tapentadol;Tiagabine;Timolol;Tizanidine;Tolmetin;Topiramate;Tramadol;Valproic acid and Divalproex;Venlafaxine;Verapamil;Zolmitriptan;Zonisamide;Nutraceuticals and medical food preparations for chronic pain: Acetyl-L-carnitine;Alpha lipoic acid;Bromelain;Capsaicin 8%;Coenzyme Q11;Magnesium;Metanx;NAC;Omega-4;PEA;Riboflavin;Vitamin D;Index by drug name;Index by use;Index by class;Abbreviations.

Additional InformationLevel: medical specialists/consultants, specialist medical trainees

August 2012 228 x 152 mm 600pp 978-0-521-75910-6 Paperback c. £39.99



Clinical Information Systems in Critical CareCecily MorrisonUniversity of Cambridge

Matthew R. JonesUniversity of Cambridge

and Julie BrackenPapworth Hospital NHS Foundation Trust

DescriptionThe complex IT requirements of a critical care unit have led to the development of numerous information systems . In this concise handbook, the authors share their experience and research findings on how to unleash the power of the technology and overcome potential problems . Clinical Information Systems in Critical Care explains the key aspects of the information systems currently available, covering topics such as how to select the best system to match the requirements of a critical care unit, the issues surrounding data maintenance, patient confidentiality and the concept of the paperless patient record . It discusses both the benefits that may justify investment in the technology and hurdles that may arise, and offers advice for avoiding common problems . Clinical Information Systems in Critical Care is essential reading for all clinicians and health managers involved in developing, implementing, maintaining and using clinical information systems .

Key Features

• Offersadviceonhowtoselectthemostappropriatesystemforaparticularorganization’srequirements,sothattechnologysupports rather than hinders practice

• Describespotentialbenefitsandpitfalls,facilitatingplanningbefore,duringandafterimplementation

• Describestherequiredhardware,providingpurchasingguidesandallowingthenon-technicalreadertounderstandthetechnicaljargon

ContentsPreface;1. Introduction: the place of information and communication in clinical practice;2. Hardware;3. Software;4. Computer networks;

5. Wireless networks;6. Hospital information systems;7. The electronic patient record;8. Decision support systems;9. The internet;10. EBM systems;

11. Telemedicine;12. PACS and data archiving systems;13. Handheld systems;14. Biochips and other implants;15. Future trends;Index.

Additional InformationLevel: medical specialists/consultants, specialist medical traineesSeries: Core Critical Care

November 2012 186 x 123 mm 200pp 50 b/w illus. 10 tables 978-0-521-15674-5 Paperback c. £14.99




Analgesia, Anaesthesia and PregnancyA Practical GuideThird edition

Steve YentisChelsea and Westminster Hospital, London

and Surbhi MalhotraSt Mary’s Hospital, London

DescriptionAnalgesia, Anaesthesia and Pregnancy focuses on pre-empting problems and maximising quality of care . Every chapter of this well-established practical guide has been completely updated and revised, retaining the concept and layout of previous editions . All aspects of obstetric medicine relevant to the anaesthetist are covered, from pre-pregnancy management to conception, throughout pregnancy, to postnatal care . Over 150 potential complications are each covered in two sections: issues raised and management options, with key points extracted into boxes for quick reference . A section on organisational aspects such as record keeping, training, protocols and guidelines makes this an important resource for any labour ward or hospital dealing with pregnant women . Presented in a clear, structured format, this practical summary will be invaluable to anaesthetists at any stage of their career who encounter obstetrics patients . Also highly beneficial for obstetricians, neonatologists, midwives, nurses and operating department practitioners wishing to extend or update their knowledge .

Key Features

• Concisestylewithbulletpointsandkeyreferencesinaclearandconsistentlayout

• Potentialproblemsandpitfallsforeachclinicalsituationarehighlighted

• Coversallaspectsofobstetricmedicinerelevanttotheanaesthetist–fromconceptiontopostnatalcare




ContentsPreface;Part I. Preconception and Conception:1. Assisted conception;2. Ovarian hyperstimulation syndrome;3. Anaesthesia before conception or confirmation of pregnancy;Part II. Pregnancy: Section 1. Procedures in Early/Mid-Pregnancy:4. Ectopic pregnancy;5. Evacuation of retained products of conception;6. Termination of pregnancy;7. Cervical suture (cerclage);8. Incidental surgery in the pregnant patient;9. Intrauterine surgery;Section 2. Normal Pregnancy and Delivery:10. Anatomy of the spine and peripheral nerves;11. Physiology of pregnancy;12. Antenatal care;13. Aortocaval compression;14. Gastric function and feeding in labour;15. Drugs and pregnancy;16. Placental transfer of drugs;17. Prescription and administration of drugs by midwives;18. Local anaesthetics;19. Normal labour;20. Intrapartum fetal monitoring;21. Pain of labour;22. Epidural analgesia for labour;23. Epidural test doses;24. Combined spinal-epidural analgesia and anaesthesia;25. Spinal analgesia;26. Spinal and epidural opioids;27. Inhalational analgesic drugs;28. Systemic analgesic drugs;29. Non-pharmacological analgesia;Section 3. Operative Delivery and Third Stage:30. Instrumental delivery;31. Caesarean section;32. Spinal anaesthesia for Caesarean section;33. Epidural anaesthesia for Caesarean section;34. General anaesthesia for Caesarean section;35. Cricoid pressure;36. Failed and difficult intubation;37. Awake intubation;38. Removal of retained placenta and perineal suturing;39. Postoperative analgesia;Section 4. Anaesthetic Problems:40. Bloody tap;41. Dural puncture;42. Postdural puncture headache;43. Epidural blood patch;

53. Shivering;54. Aspiration of gastric contents;55. Awareness;56. Air embolism;Section 5. Problems Confined to Obstetrics:57. Induction and augmentation of labour;58. Oxytocic and tocolytic drugs;59. Premature labour, delivery and rupture of membranes;60. Malpresentations and malpositions;61. External cephalic version;62. Multiple pregnancy;63. Trial of scar;64. Under-age pregnancy and advanced maternal age;65. Placenta praevia;66. Placental abruption;67. Prolapsed cord;68. Fetal distress;69. Shoulder dystocia;70. Intrauterine death;71. Uterine inversion;72. Major obstetric haemorrhage;73. Postpartum haemorrhage;74. Collapse on labour ward;75. Maternal cardiopulmonary resuscitation;76. Amniotic fluid embolism;77. Cholestasis of pregnancy (obstetric cholestasis);78. Acute fatty liver of pregnancy;79. HELLP syndrome;80. Hypertension, pre-eclampsia and eclampsia;81. Magnesium sulphate;82. Hyperemesis gravidarum;83. Maternal mortality;Section 6. Problems Not Confined to Obstetrics:84. Allergic reactions;85. Cardiovascular disease;86. Arrhythmias;87. Pulmonary oedema;88. Cardiomyopathy;89. Coarctation of the aorta;90. Prosthetic heart valves;91. Congenital heart disease;92. Pulmonary hypertension and Eisenmenger’s syndrome;93. Ischaemic heart disease;94. Endocrine disease;95. Diabetes mellitus;96. Anaemia and polycythaemia;97. Deep-vein thrombosis and pulmonary embolism;98. Thrombophilia;99. Coagulopathy;

110. Neurological disease;111. Meningitis;112. Acute post-infective peripheral neuropathy (Guillain–Barré syndrome);113. Past history of neurological trauma;114. Benign intracranial hypertension;115. Intracranial tumour;116. Cerebrovascular accident;117. Epilepsy;118. Migraine;119. Multiple sclerosis;120. Myasthenia gravis;121. Spina bifida;122. Convulsions;123. Respiratory disease;124. Asthma;125. Cystic fibrosis;126. Pulmonary fibrosis;127. Sarcoidosis;128. Acute lung injury (acute respiratory distress syndrome);129. Pneumonia;130. Sepsis;131. Hepatitis;132. Herpes simplex infection;133. HIV infection;134. Malaria;135. Pyrexia during labour;136. Migrants/disadvantaged women;137. Psychiatric disease;138. Substance abuse;139. Obesity;140. Renal failure;141. Steroid therapy;142. Trauma in pregnancy;143. Malignant disease;144. Transplantation;145. Critical care in pregnancy;146. Invasive monitoring;Section 7. The Neonate: 147. Neonatal assessment;148. Neonatal physiology and pharmacology;149. Neonatal resuscitation;150. Perinatal mortality;Part III. Puerperium and After: 151. Drugs and breastfeeding;152. Follow-up;153. Maternal satisfaction;Part IV. Organisational Aspects: 154. Antenatal education;155. Audit;156. Labour ward organisation;157. Midwifery training;158. Consent;159. Medicolegal aspects;

Additional InformationLevel: specialist medical trainees, medical specialists/consultants

October 2012 234 x 156 mm 432pp 13 b/w illus. 978-1-107-60159-8 Paperback c. £42.00



Regional Anesthesia in TraumaA Case-Based Approach

Jeff GadsdenColumbia University College of Physicians and Surgeons

DescriptionThe management of pain from acute injuries is a priority in trauma care . Regional analgesic techniques are very effective at treating acute pain and are gaining in popularity as recognition of their beneficial effects on morbidity increases . Regional Anesthesia in Trauma employs multiple narrative problem-solving case scenarios that explore the use of regional anesthesia in: •Bluntchesttrauma,amputations,upperandlowerextremityfracturesandspinalinjury •Burninjury •Patientswithpre-existingnerveinjuryandotherco-morbidities •Patientsatriskforcompartmentsyndrome •Pregnant,obese,elderlyandpediatricpatients •Localanestheticsystemictoxicity With a focus on ultrasound-guided techniques, the reader is guided through the technical aspects of performing regional anesthesia as well as the medical and surgical considerations that influence the choice of analgesic therapy . Regional Anesthesia in Trauma is invaluable for practitioners and trainees in anesthesiology, emergency medicine and trauma surgery .

Key Features

• Providesabroadscopeofapproachesandsolutionstotraumaticpainmanagementfromthesceneoftheaccidenttotherehabilitation phase

• Therealclinicalcasesplacetheblocktechniquesinarealcontext,consideringeachpatientasawholeratherthanjustalimbtobe blocked

• Coverscontroversialmanagementtopicstoencourageconsiderationoftheprosandconsforvarious‘hottopics’suchasnerveblocks in those at risk from complications

ContentsPreface;1. Principles of pain management in trauma care;2. Acute pain, regional anesthesia and the stress response;3. The progression from acute to chronic pain;4. Prehospital regional anesthesia;5. Regional anesthesia and digital replantation;6. Regional anesthesia and compartment syndrome;

7. Regional anesthesia for blunt chest trauma;8. Regional anesthesia, trauma, and complex regional pain syndrome;9. Regional anesthesia and combat care;10. Regional anesthesia for pediatric trauma;11. Regional anesthesia for fractured neck of femur;12. Regional anesthesia in the intoxicated trauma patient;13. Regional anesthesia for humeral shaft fracture;14. Regional anesthesia for burns;

15. Regional anesthesia, penetrating abdominal trauma and sepsis;16. Regional anesthesia in the injured obese patient;17. Regional anesthesia and lower extremity trauma;18. Regional anesthesia and traumatic limb amputation;19. Complications of brachial plexus blockade;20. Regional anesthesia and trauma in pregnancy;21. Regional anesthesia and the injured athlete;Index.


October 2012 234 x 156 mm 156pp 68 b/w illus. 17 tables 978-1-107-60223-6 Paperback c. £35.00




Operating Room Leadership and ManagementEdited by Alan KayeLouisiana State University

Charles FoxDepartment of Anesthesiology, Tulane Hospital, New Orleans

and Richard UrmanHarvard Medical School

DescriptionEffective management of the OR is critical in all clinical settings, where ensuring that policies, systems, staff members and teams are efficient, safe and cost-effective is paramount . OperatingRoomLeadershipandManagement is a comprehensive resource for physicians and administrators involved in the day-to-day management of operating rooms in a hospital setting or smaller-scale facilities . Topics include: •ORmetrics •Scheduling •Humanresourcemanagement •Leadership •Economics •ITmanagement •Qualityassurance •Recovery. This practical, evidence-based text is written by leaders in the field of OR management and is relevant to medical directors, administrators and managing physicians . Specific nursing considerations, preoperative patient evaluation, financial performance measures and pain clinic management are also discussed in detail . OperatingRoomLeadershipandManagementenables all OR managers to improve the efficiency and performance of their operating rooms .

Key Features

• AllORsettingsdiscussed–includinghospitals,ambulatorycenters,offices

• Focusesonmaximizingtheefficiencyofoperatingroomutilization,staffandmaterials

• Theperfectresourcetoenableyoutominimisepatientdelays,maintainhighpatientsatisfactionscoresandmanageORstaffeffectively




ContentsForeword;Preface;1. Hospital strategic planning and implications for the OR manager;2. Financial decision-making for the hospital administrator;3. Perioperative leadership;4. Preoperative clinic management;5. Operating room metrics and scheduling;6. Analyzing financial and operational performance;7. Perioperative nursing and all complexities;

8. Perioperative staffing and compensation;8. Human resource management;9. Electronic data for perioperative period;10. Staff, quality, pay-for-performance;11. The Joint Commission, CMS, other standards;12. Surgical organization;13. Post anesthesia care unit (PACU);14. Ambulatory and office-based settings;15. Office-based practice;

16. Anesthesia practice management;17. Pain practice management;18. Future of perioperative management;19. Reengineering the OR function: clinical considerations;20. Construction and design: technical considerations;21. Simulation and safety in the OR;22. Billing and coding (anesthesia and surgery);23. Surgical and facility billing;24. Moderate and deep sedation practices;25. Perioperative efficiency and throughput.


October 2012 246 x 189 mm 300pp 978-1-107-01753-5 Hardback c. £65.00



Anesthesia for Otolaryngologic SurgeryEdited by Basem AbdelmalakCleveland Clinic Foundation

and John DoyleCleveland Clinic Foundation

DescriptionAnesthesia for Otolaryngologic Surgery offers a comprehensive synopsis of the anesthetic management options for otolaryngologic and bronchoscopic procedures . Authored by world authorities in the fields of anesthesiology and otolaryngology, both theoretical concepts and practical issues are addressed in detail, providing literature-based evidence wherever available and offering expert clinical opinion where rigorous scientific evidence is lacking . A full chapter is dedicated to every common surgical ENT procedure, as well as less common procedures such as face transplantation . Clinical chapters are enriched with case descriptions, making the text applicable to everyday practice . Chapters are also enhanced by numerous illustrations and recommended anesthetic management plans, as well as hints and tips that draw on the authors’ extensive experience . Comprehensively reviewing the whole field, Anesthesia for Otolaryngologic Surgery is an invaluable resource for every clinician involved in the care of ENT surgical patients, including anesthesiologists, otolaryngologists and pulmonologists .

Key Features

• Afullycomprehensivereviewofotolaryngologicpathologyandrelatedanestheticmanagement,offeringeasyaccesstovaluableclinical information

• Includesaseriesofclinicalcasestudies,enablinglearningfromrealexperience

• Providesrecommendedanesthesticmanagementplans,aidingquickandaccuratemanagementofotolaryngologicsurgicalpatients

ContentsPart I. Introduction:1. Clinical head and neck anatomy for the ENT anesthesiologist;2. Otolaryngology instruments 101 for the anesthesiologist;3. Preoperative evaluation for ENT surgery;4. The difficult airway in otolaryngology;5. Preoperative endoscopic airway examination (PEAE);6. Awake intubation;7. Anesthesia for ENT trauma;8. Anesthesia for ENT emergencies;9. Airway pathology in otolaryngology: anesthetic implications;10. Use of heliox in managing stridor: an ENT perspective;11. Prevention and management of airway fires;Part II. Anesthesia for Nasal, Sinus and Pituitary Surgery:

12. Anesthesia for septoplasty and rhinoplasty;13. Endoscopic sinus surgery;14. Transsphenoidal pituitary surgery;Part III. Anesthesia for Head and Neck Surgery:15. Neck dissection and laryngectomy;16. Anesthesia for head and neck flap reconstructive surgery;17. Anesthesia for thyroid and parathyroid surgery;18. Anesthesia for obstructive sleep apnea surgery;19. Perioperative anesthetic management of carotid body tumor resection;20. Anesthesia for Zenker’s Diverticulectomy;21. Anesthesia for parotid surgery;22. Anesthesia for maxillary, salivary gland, mandibular and temporomandibular joint surgery;23. Anesthetic care for face transplantation;

24. Anesthesia for EUA and panendoscopy;25. Anesthesia for ENT laser surgery;Part IV. Anesthesia for Laryngotracheal Surgery:26. Anesthesia for laryngoplasty;27. Anesthesia for tracheotomy;28. Anesthesia for tracheal resection;29. Anesthesia for otologic and neurotologic surgery;Part V. Anesthesia for Bronchoscopic Surgery:30. Anesthesia care for diagnostic bronchoscopic procedures;31. Anesthesia care for therapeutic bronchoscopic procedures;Part VI. Anesthesia for Pediatric ENT Surgery:32. Anesthesia for pediatric otolaryngologic surgery;33. Reconstructive airway surgery in pediatrics;Index.


October 2012 246 x 189 mm 400pp 41 b/w illus. 112 colour illus. 46 tables 978-1-107-01867-9 Hardback c. £65.00



12 Emergency psychiatry

Emergency PsychiatryArjun ChanmugamJohn Hopkins Medical Institutions

Patrick TriplettJohn Hopkins Medical Institutions

and Gabor KelenThe Johns Hopkins University

DescriptionMany healthcare providers based in primary care, emergency care or other acute care environments encounter patients with psychiatric problems . These presentations can be difficult to manage and often pose significant challenges . A better understanding of most common psychiatric problems can greatly aid both providers and patients . Emergency Psychiatry reviews a wide range of common psychiatric disorders and provides succinct management guidelines . Written by emergency physicians and psychiatrists, Emergency Psychiatry is a rapid reference for the acute management of psychiatric disorders for all care providers, including, but not limited to, emergency physicians, internists, psychiatrists, social workers, family practitioners and other primary care providers .

Key Features

• Comprehensive,succinctreviewofthemostcommonacutepsychiatricpresentations

• Providesstraightforwardrecommendationsforpracticalapplication

• Writtenandeditedbybothemergencyphysiciansandpsychiatrists

ContentsPreface;1. General approach;2. Management of agitation and violence;3. Suicide assessments;4. Managing substance abuse;5. The psychotic patient;

6. The delirious patient;7. The anxious patient;8. Mood disorders;9. Personality disorders;10. Geriatric psychiatry;11. Medicolegal and risk management;

12. Pediatric psychiatry;13. Emergency department evaluation of intellectual and developmental disabilities;14. Eating disorders;15. Chronic pain;16. Death, dying and grief;17. Pregnancy and women’s issues;18. Multicultural issues and safety.

Additional InformationLevel: medical specialists/consultants, professionals

February 2013 234 x 156 mm 256pp 978-0-521-87926-2 Hardback c. £65.00



13Emergency psychiatry

Behavioral Emergencies for the Emergency PhysicianEdited by Leslie ZunDepartment of Emergency Medicine, Mt Sinai Hospital, Chicago

Edited in association with Lara G. ChepenikYale University School of Medicine

and Mary Nan S. MalloryUniversity of Louisville, School of Medicine

DescriptionEmergency physicians, in all practice settings, care for patients with both undifferentiated psycho-behavioral presentations and established psychiatric illness . This reference-based text goes beyond diagnostics, providing practical input from physicians experienced with adult emergency psychiatric patients . Physicians will increase their understanding and gain confidence working withthesepatients,evenwhenspecializedpsychiatricback-upislacking.BehavioralEmergenciesfortheEmergencyPhysician is comprehensive, covering the pre-hospital setting and advising on evidence-based practice; from collaborating with psychiatric colleaguestoestablishingapsychiatricserviceinyourED.Sedation,restraintandseclusionareoutlined.Potentialdilemmaswhentreating pregnant, geriatric or homeless patients with mental illness are discussed in detail, along with the more challenging behavioral diagnoses such as malingering, factitious and personality disorders . This go-to, comprehensive volume is invaluable for trainee and experienced emergency physicians, as well as psychiatrists, psychologists, psychiatric and emergency department nurses and other mental health workers .

Key Features

• Guidetoevaluationandtreatmentofbehavioralpatientsaidsquickandappropriatemanagement

• Comprehensivevolumeprovidinginformationonallaspectsofpsychiatricandbehavioralemergencies

• Writtenbypractisedclinicians,drawingontheirownexperiencetodepictrealisticscenariosandoutcomes



14 Emergency psychiatry

ContentsPreface;Part I. General Considerations for Psychiatric Care in the Emergency Department:1. The magnitude of the problem of psychiatric illness presenting in the emergency department;2. Delivery models in emergency psychiatric care;Part II. Evaluation of the Psychiatric Patient:3. The medical clearance process for psychiatric patients presenting acutely to the emergency department;4. Advanced interviewing techniques for psychiatric patients in the emergency department;5. Use of routine alcohol and drug testing for psychiatric patients in the emergency department;6. Drug intoxication in psychiatric patients in the emergency department;7. Drug withdrawal syndromes in psychiatric patients in the emergency department;Part III. Psychiatric Illnesses:8. The patient with depression in the emergency department;9. Assessment of the suicidal patient in the emergency department;10. The patient with somatoform disorders in the emergency department;11. The patient with anxiety disorders in the emergency department;12. The patient with post traumatic stress disorder in the emergency department;13. The patient with psychosis in the emergency department;14. Personality disorders in the acute setting;15. The patient with factitious disorders and malingering in the emergency department;

16. The patient with delirium and dementia in the emergency department;17. The patient with excited delirium in the emergency department;18. Medical illness in psychiatric patients in the emergency department;19. Acute care of eating disorders;20. Management of the emergency department patient with co-occurring substance abuse disorder;Part IV. Treatment of the Psychiatric Patient:21. Use of verbal de-escalation techniques in the emergency department;22. Use of agitation treatment in the emergency department;23. Management of aggressive and violent behavior in the emergency department;24. Restraint and seclusion techniques in the emergency department;25. Use of psychiatric medications in the emergency department;26. The patient with neuroleptic malignant syndrome in the emergency department;27. Treatment of psychiatric illness in the emergency department;28. Rapidly acting treatment in the emergency department;Part V. Special Populations:29. Pediatric psychiatric disorders in the emergency department;30. Geriatric psychiatric emergencies;31. Disaster and terrorism emergency psychiatry;32. Trauma and loss in the emergency setting;

33. Management of homeless and disadvantaged persons in the emergency department;34. Management of neurobehavioral sequelae of traumatic brain injury in the emergency department;35. Management of psychiatric illness in pregnancy in the emergency department;36. Cultural concerns and issues in emergency psychiatry;37. Rural emergency psychiatry;Part VI. Administration of Psychiatric Care:38. Coordination of emergency department psychiatric care with psychiatry;39. Integration with community resources;40. The role of telepsychiatry;41. Emergency medical services psychiatric issues;42. Triage of psychiatric patients in the emergency department;43. The Emergency Medical Treatment and Active Labor Act (EMTALA) and psychiatric patients in the emergency department;44. Assessing capacity, involuntary assessment, and leaving against medical advice;45. Best practices for the evaluation and treatment of patients with mental and substance use illness in the emergency department;46. Improving emergency department process and flow;47. Physical plant for emergency psychiatric care;48. Legal issues in the care of psychiatric patients;49. Law enforcement and emergency psychiatry;50. Research in emergency psychiatry;Index.


February 2013 276 x 219 mm 352pp 13 b/w illus. 978-1-107-01848-8 Paperback c. £55.00


15General medicine

Values-Based Interprofessional Collaborative PracticeWorking Together in Health Care

Jill E. ThistlethwaiteUniversity of Queensland

DescriptionThe provision of care within the context of the modern health service environment involves a wide range of professionals . The health care team might include general practitioners, nurses, midwives, hospital doctors, physiotherapists, other allied health professionals, as well as receptionists and practice managers . To optimise delivery of care at both individual and population levels, team members must work collaboratively with colleagues in their own professionandothers.Thisbook,intheValues-BasedMedicineseries,addsthedimensionof values to the more usual discussions of teamwork, considering interactions between health care professionals and how these might be affected by differences in professional and personal values . Examples of scenarios based on real-life experience promote learning and reflection . Anybody working or training in health care and who aspires to collaborate successfully with their colleagues in other specialties will find this book extremely valuable, as will educators who facilitate learners in teamwork .

Key Features

• Focusesonteamworkandcollaborativepracticefromavalues-basedperspective,complementingtheevidence-basedpracticeofmodern health care

• Clinicalscenariosandreflectionpointsfacilitatelearningfromrealpractice

• Commentsfrompatientsandarangeofhealthcareworkersprovideawiderperspective

ContentsPreface;Part I. Introduction and Theory:1. Values-based practice in health care: setting the scene;2. Teamwork and collaborative practice in modern health care;3. Communication within teams and between professionals;Part II. Primary Care and the Primary Health Care Team:

4. A patient complaint: team meetings, policy and practice values – raising awareness in the team;5. A well person health check, health promotion and disease prevention: different lifestyles, different values;6. A patient with medically unexplained symptoms: applying evidence and values;7. A request for strong analgesia: honesty and truth;8. Asylum seekers and refugees: working across cultures;9. A request for a home birth and other pregnancy related consultations;10. Community-based care and the wider health care team;

11. Ageing and end of life decisions;12. Referrals and the interface between primary and secondary care: looking after ‘our’ patients;13. Living with visible difference and valuing appearance;14. Collaboration with other professionals: in and outside health care;15. Learning in and about teams;Afterword;Index.

Additional InformationLevel: medical specialists/consultants, specialist medical traineesSeries: Values-BasedMedicine

September 2012 234 x 156 mm 200pp 3 b/w illus. 978-1-107-63616-3 Paperback c. £29.99



16 Medical imaging

Digital MammographyA Practical Approach

Edited by Gary J. WhitmanMD Anderson Cancer Center

and Tamara Milner HaygoodMD Anderson Cancer Center

DescriptionDigitalmammographyhasmanyadvantagesoverfilm-screenmammography,includingfaster acquisition, easier storage and easier retrieval of images . Written by expert radiologists and physicists, DigitalMammography:APracticalApproach compares digital mammography to conventional film-screen mammography, reviews clinical cases and explores newer modalities . Key topics include: •Digitaldetectors •Monitors •Imageacquisition •Imagestorage,retrievalandtransfer •Imageinterpretationandefficacy •Artifacts •Acomparisonofcommerciallyavailablesystems •Mobiledigitalmammography. An image atlas and sections on digital tomosynthesis and computed tomography of the breast enhance the text . DigitalMammography: A Practical Approach melds the worlds of clinical radiology and physics in an easy-to-understand, practical resource . A valuable addition to the shelf of radiologists, radiologic technicians, practising medical physicists and mammography technologists; and any practitioners developing and expanding digital mammography programs .

Key Features

• Includesclinicalcasestoenablereaderstolearnfromtheexperienceofothers

• Practicalinformationoneveryaspectofthetechniqueaidsinorganizingandexecutingadigitalmammographyprogram

• Featurescurrentandemerginginformationondigitalmammographyandthenewtechnique,digitaltomosynthesis

ContentsPreface;1. Detectors for digital mammography;2. Image acquisition;3. Preparing digital mammography images for interpretation;4. Image display and visualization in digital mammography;

5. PACS, storage and archiving – our experience at a private outpatient facility;6. Interpretation of digital screening mammography;7. Efficacy of digital screening mammography;8. Artifacts in digital mammography;9. Mobile digital mammography;

10. Procedures with digital mammography;11. Digital breast tomosynthesis;12. Breast computed tomography;13. Cases;14. Comparison of commercially available systems;Index.


November 2012 276 x 219 mm 264pp 328 b/w illus. 978-0-521-76372-1 Hardback c. £65.00



17Medical imaging

Pearls and Pitfalls in Emergency RadiologyVariants and Other Difficult Diagnoses

Edited by Martin L. GunnUniversity of Washington School of Medicine

DescriptionRapidrecognitionoflife-threateningillnessesandinjuriesexpeditesappropriatemanagementandimprovesclinicaloutcomes.False-positive interpretations in radiology have been identified as a significant cause of error, leading to unnecessary investigation and treatment, increased healthcare costs, and delays in appropriate management . Moreover, it is important that radiologists do not miss important subtle diagnoses that need urgent intervention . Pearls and Pitfalls in Emergency Radiology provides an outline of common imaging artefacts, anatomic variants and critical diagnoses that the radiologist must master in order to guide appropriate care and avoidmalpracticelawsuits.Onehundredselectedcases–illustratedwithseveralhundredimagesfromMRI,MDCT,PET,ultrasoundandradiographs–arepresentedinasuccinctandstructuredformat,highlightingkeypearlsandpotentialdiagnosticpitfalls.Thetextfocuses on emergent presentations of diseases in all body regions in both adults and children .

Key Features

• Thestructuredformatandkeypointsprovideaquickreferencepointfortheemergencydepartment

• Over100casesprovideafullyillustratedcompendiumofwhattolookforandwhattodismiss

• Describesimportantdiagnosesthatarecommonlymissedormisinterpreted



18 Medical imaging

ContentsPreface;List of contributors;Part I. Brain, Head, and Neck: Section 1. Neuro: Extra-axial and Vascular:1. Isodense subdural hemorrhage;2. Nonaneurysmal perimesencephalic subarachnoid hemorrhage;3. Missed intracranial hemorrhage;4. Pseudo-subarachnoid hemorrhage;5. Arachnoid granulations;6. Ventricular enlargement;7. Blunt cerebrovascular injury;8. Internal carotid artery dissection presenting as subacute ischemic stroke;9. Mimics of venous sinus thrombosis;10. Pineal cyst;Section 2. Neuro: Intra-axial:11. Enlarged perivascular space;12. Tumefactive demyelination;13. Cavernous malformation simulating contusion;Section 3. Neuro: Head and Neck:14. Orbital infection;15. Diffuse axonal injury;16. Globe injuries;17. Dilated superior ophthalmic vein;18. Orbital fractures;Part II. Spine:19. Variants of the upper cervical spine;20. Atlantoaxial rotatory fixation versus head rotation;21. Cervical flexion and extension radiographs after blunt trauma;22. Pseudosubluxation of c2-3;23. Calcific tendinitis of the longus colli;24. Motion artifact simulating spinal fracture;25. Pars interarticularis defects;26. Limbus vertebra;27. Transitional vertebrae;28. Subtle injuries in ankylotic spine disorders;29. Spinal dural arteriovenous fistula;Part III. Thorax:30. Pseudopneumomediastinum;31. Traumatic pneumomediastinum without aerodigestive injury;32. Pseudopneumothorax;33. Subcutaneous emphysema and mimickers;

34. Tracheal injury;35. Pulmonary contusion and laceration;36. Sternoclavicular dislocation;37. Boerhaave syndrome;38. Variants and hernias of the diaphragm simulating injury;Part IV. Cardiovascular:39. Pulsation artifact simulating blunt traumatic aortic injury;40. Mediastinal widening due to non-hemorrhagic causes;41. Aortic injury with normal mediastinal width;42. Mimics of hemopericardium on fast;43. Mimics of acute thoracic aortic syndromes: aortic dissection, intramural hematoma and penetrating aortic ulcer;44. Aortic intramural hematoma;45. Retrocrural periaortic hematoma;46. Peripheral CT angiography on fast CT scanners;47. Breathing artifact simulating pulmonary embolism;48. Acute versus chronic pulmonary thromboembolism;49. Vascular embolization of foreign body;Part V. Abdomen: Section 4. General:50. Simulated active bleeding;51. Pseudopneumoperitoneum;52. Intra-abdominal focal fat infarction: epiploic appendagitis and omental infarction;53. False negative and positive fast;Section 5. Liver and Biliary:54. Diaphragmatic slip simulating liver laceration;55. Gallbladder wall thickening due to non-biliary causes;Section 6. Spleen:56. Splenic clefts;57. Inhomogeneous splenic enhancement;Section 7. Pancreas:58. Pseudopancreatitis following trauma;59. Pancreatic clefts;60. Pseudosubcapsular splenic hematoma;Section 8. Bowel:61. Pseudothickening of the bowel wall;62. Small bowel transient intussusception;63. Duodenal diverticulum;64. Pseudopneumatosis;65. Pneumatosis intestinalis;66. Pseudoappendicitis;Section 9. Kidney and Ureter:

67. Missed renal collecting system injury;68. Pseudohydronephrosis;Part VI. Pelvis: Section 10. General:69. Physiologic pelvic intraperitoneal fluid;70. Avoiding missed injuries to the bowel and mesentery: the importance of intraperitoneal fluid;Section 11. Obstetrics and Gynecology:71. Endometrial hypodensity simulating fluid;72. Pseudogestational sac;73. Cystic pelvic mass simulating the bladder;74. Ovarian torsion;Section 12. Other Soft Tissue:75. Urine jets simulating a bladder mass;76. Extraluminal bladder foley catheter;77. Missed bladder rupture;Part VII. Musculoskeletal:78. Pseudofracture from motion artefact;79. Mach effect;80. Foreign bodies not visible on radiographs;81. Accessory ossicles;82. Fat pad interpretation;83. Posterior shoulder dislocation;84. Easily missed fractures in thoracic trauma;85. Sesamoids and bipartite patella;86. Subtle knee fractures;87. Lateral condylar notch sign;88. Easily missed fractures of the foot and ankle;Part VIII. Pediatrics:89. Thymus simulating mediastinal hematoma;90. Foreign body aspiration;91. Idiopathic ileocolic intussusception;92. Ligamentous laxity and intestinal malrotation in the infant;93. Hypertrophic pyloric stenosis and pylorospasm;94. Retropharyngeal pseudothickening;95. Pediatric cranial sutures simulating fractures;96. Systematic review of elbow injuries;97. Pelvic pseudofractures: normal physeal lines;98. Hip pain in the child;99. Common pitfalls in pediatric fractures: ones not to miss;100. Non-accidental trauma: neuroimaging;101. Non-accidental trauma: skeletal injuries;Index.


January 2013 276 x 219 mm 410pp 792 b/w illus. 25 colour illus. 978-1-107-02191-4 Hardback c. £65.00


19Medical imaging

Pearls and Pitfalls in Head and Neck and NeuroimagingVariants and Other Difficult Diagnoses

Nafi AygunThe Johns Hopkins University

Gaurang ShahUniversity of Michigan Health System, B2A209

and Dheeraj GandhiUniversity of Maryland Medical Center

DescriptionPearlsandPitfallsinHeadandNeckandNeuroimaging illustrates and describes the imaging entities that can cause confusion and mismanagement in daily radiological practice . Frequentinterpretationerrorsarecoveredin105casesthatprovidereal-lifeclinicalscenariosforfocusedandpracticallearning.Thechosen cases represent a modern neuroradiology practice and cover the brain, spine and head and neck regions, including the full panoplyofimagingmodalities.Theunderlyingreasonsforcommonmistakesareanalyzedandradiologicfindingsthathelpwiththecorrectdiagnosisareemphasized.Adifferentialdiagnosisisprovidedforeachcasewithexamplesofalternativediagnoses,allowingreaders to visually grasp the differentiating features . PearlsandPitfallsinHeadandNeckandNeuroimaging provides a valuable resource for general and sub-specialist radiologists needing to improve their diagnostic proficiency in adult and pediatric patients . This book also serves as a preparation resource for recertification exams in radiology .

Key Features

• Focusesoncommonlymisdiagnosedconditions,alertingradiologistsofcommonpitfallsandteachingthemhowtoavoidthesemistakes

• Providesreal-lifeclinicalscenarios,enablinglearningfromexperience

• Givesexamplesofalternativediagnoses,allowingreaderstovisuallygraspdifferentiatingfeaturesandmakethecorrectdiagnosis

ContentsPreface;Part I. Brain;Part II. Spine;Part III. Head and Neck;Index.


November 2012 276 x 219 mm 320pp 600 colour illus. 978-1-107-02664-3 Hardback c. £65.00



20 Medical law, medical ethics, forensic medicine

Research EthicsA Philosophical Guide to the Responsible Conduct of Research

Edited by Gary ComstockDepartment of Philosophy & Religion, North Carolina State University, Raleigh

DescriptionOrdinarily, responsible conduct of research (RCR) ‘training’ consists of lectures accompanied by generic exercises on ‘core’ topics . Research Ethics takes a novel, philosophical approach to the RCR and the teaching of moral decision-making . Part I introduces egoism and explains that it is in the individuals own interest to avoid misconduct, fabrication of data, plagiarism and bias . Part II takes up contractualism and covers issues of authorship, peer review and responsible use of statistics . Part III introduces moral rights as the basis of informed consent, the use of humans in research, mentoring, intellectual property and conflicts of interests . Part IV uses two-level utilitarianism to explore the possibilities and limits of the experimental use of animals, duties to the environment and future generations, and the social responsibilities of researchers . This book replaces mind-numbing rote exercises with an adventure in moral imagination and is an essential guide for graduate students in all disciplines .

Key Features

• FirstbooktoorganizeallRCRtopicsaccordingtoastep-by-stepdecision-makingprocedure

• Usefulforstudentsinalldisciplines,fromnaturalsciencestosocialsciencesandfromengineeringtomedicine

• Stimulatesreaderstoaskquestionsaboutthesubjectratherthansimplytomemorizerulesandregulations

ContentsIntroduction;Part I. Protect my Interests:1. Report misconduct;2. Avoid plagiarism;3. Beware intuition;4. Justify decisions;Part II. Promote our Interests:

5. Articulate reasons;6. Write cooperatively;7. Protect manuscripts;8. Clarify statistics;Part III. Respect Strangers’ Rights:9. Inform subjects;10. Mentor inclusively;

11. Recognize property;12. Reveal conflicts;Part IV. Honor All Interests:13. Treat humanely;14. Preserve environments;15. Cultivate responsibility;Conclusion.

Additional InformationLevel: medical specialists/consultants, academic researchers

December 2012 234 x 156 mm 335pp 13 b/w illus. 7 tables 978-0-521-18708-4 Paperback c. £27.99



21Medical law, medical ethics, forensic medicine

Genetic Research on AddictionEthics, the Law, and Public Health

Edited by Audrey ChapmanUniversity of Connecticut School of Medicine

DescriptionThe manner in which genetic research associated with addiction is conducted, interpreted and translated into clinical practice and policy initiatives raises important social, ethical and legal issues . Genetic Research on Addiction fulfils two key aims; the first is to identify the ethical issues and requirements arising when carrying out genetically-based addiction research, and the second is to explore the ethical, legal and public policy implications of interpreting, translating and applying this research . The book describes research guidelines on human protection issues such as improving the informed consent process, protecting privacy, responsibilities to minors and determining whether to accept industry funding . The broader public health policy implications of the research are explored and guidelines offered fordevelopingeffectivesocialinterventions.Highlyrelevantforclinicians,researchers,academics and policy-makers in the fields of addiction, mental health and public policy .

Key Features

• Providesanoverviewofethicalchallengeswhenconductinggeneticresearchonaddiction,aidingidentificationofpotentialproblems

• Considersawiderangeofhumansubjectprotectionissuesandprovidespracticalrecommendationsandguidelines

• Exploresethicalissuesintranslatinggeneticresearchonaddictionintopolicy

ContentsAbstracts;Part I. Introduction:1. Introduction to volume;2. The implications of genetic research on alcohol dependence for prevention and treatment;3. Promises and risks for participants in studies of genetic risk for alcohol or drug dependence;Part II. Research Ethics:4. Improving the informed consent process in research with substance abusing participants;

5. Ethical responsibilities to minor children with drug abusing parents in research trials;6. Protecting privacy in genetic research on alcoholism and other addictions;7. Uses and limitations of certificates of confidentiality for protecting research on addiction;8. Ethical issues in genomic databases and biobanks involving human subjects;9. Should addiction researchers accept funding derived from the profits of addictive consumptions?;10. Ethical issues related to alcohol research funding from the alcohol beverage industry;Part III. Translating Addiction Research:

11. The public health implications of genetic research on addiction;12. Genetics, addiction, and stigma;13. Lay beliefs about genetic influences on alcoholism: implications for prevention and treatment;14. Personalizing risk: how behavioral genetics research into addiction makes the political personal;Part IV. Conclusions:15. Conclusions and guidelines for conducting and translating research on alcohol dependence and addiction;Index.

Additional InformationLevel: professionals

August 2012 234 x 156 mm 272pp 1 b/w illus. 978-1-107-65334-4 Hardback c. £55.00



22 Mental health, psychiatry and clinical psychology

The Maudsley Reader in Phenomenological PsychiatryEdited by Matthew BroomeUniversity of Warwick

Robert HarlandSouth London and Maudsley NHS Foundation Trust

Gareth S. OwenInstitute of Psychiatry, London

and Argyris StringarisInstitute of Psychiatry, London

DescriptionThe interaction between philosophy and clinical psychopathology in the form of the ‘phenomenological movement’ was one of the most significant events to occur in mental health over the course of the last century . As the gulf between ‘analytical’ and ‘continential’ philosophy reduces, and as clinical psychiatrylooksbeyondDSM-IVandICD-10,thereisrenewedenthusiasmforphenomenologicalthinking.Thisuniquebookbringstogether and interprets previously hard to find texts, new translations and passages detailing the interplay between philosophy and psychopathology, making them accessible to a new generation of mental health researchers, practitioners and policy makers . The content charts both the influence of key philosophers on ways of thinking and describes the impact and influence of phenomenological approaches to clinical work and understanding in a variety of mental disorders .

Key Features

• Presentsauniquecollectionofkeyphilosophicaltextsfornon-philosopherssummarizingphenomenologicalmethodologyinphilosophy

• Bringstogetherhard-to-findprimarysourcesinpsychiatryandincludesnewtranslationspreparedspecificallyforthisvolume

• Includesbriefandclearcommentarieslinkingreadingsandputtingthemintocontext



23Mental health, psychiatry and clinical psychology

ContentsPrologue;How to read this book;Acknowledgements;Part I. Intellectual Background:1. Introduction;Section 1. Influences on Phenomenology:2. Franz Brentano (1838–1917): Brentano, F. (1887), ‘The Concept of a Descriptive Psychology’;Brentano, F. (1874), ‘The Distinction between Mental and Physical Phenomena’;3. Wilhelm Dilthey (1833–1911): Dilthey, W. (1894), ‘Ideas about a Descriptive and Analytical Psychology’;4. Max Weber (1864–1920): Weber, M. (1949), ‘Objectivity’ in Social Science and Social Policy’;5. Henri Bergson (1859–1941): Bergson, H. (1910), Selections from ‘Time and Free Will: An Essay on the Immediate Data of Consciousness’;Section 2. Phenomenological Philosophy:6. Edmund Husserl (1859–1938): Husserl, E. (1919), ‘Ideas 1’;Husserl, E. (1948), Selections from ‘Experience and Judgment’;7. Max Scheler (1874–1928): Scheler, M. (1913–14) ‘Phenomenology and the Theory of Cognition’;Scheler, M. (1928), Selections from ‘Man’s Place in Nature’;Scheler, M. (1913–16), ‘Feeling and Feeling States’;Scheler, M. (1922), Selections from ‘The Nature of Sympathy’;

Scheler, M. (1914), ‘On the Idea of Man’;Scheler, M. (1928), Selections from ‘The Human Place in the Cosmos’;8. Martin Heidegger (1889–1976): Heidegger, M. (1919), ‘The Idea of Philosophy and the Problem of Worldview,’ War Emergency Semester;Heidegger, M. (1994), Selections from ‘Introduction to Phenomenological Research’;Heidegger, M. (1927), ‘The Worldhood of the World’;Heidegger, M. (1927), ‘Fear as a Mode of State-of-Mind’;Part II. The Phenomenological Approach in Psychiatry:9. Introduction;10. Jaspers’ approach 1: static understanding –‘phenomenology’: Jaspers, K. (1912), ‘The Phenomenological Approach in Psychopathology’;11. Jaspers’ approach 2: genetic understanding –‘Verstehen’: Jaspers, K. (1959), ‘Meaningful psychic connections’;12. Minkowski’s structural approach: Minkowski, E. (1933), ‘The Notion of a Generating Disorder and the Structural Analysis of Mental Disorders’;13. Binswanger’s existential approach: Binswanger, L. (1946), ‘The Existential Analysis School of Thought’;Part III. Phenomenologies of Mental Disorder:14. Introduction;15. Brain injury: Goldstein, K. (1940), ‘Pathology and the Nature of Man: The Abstract Attitude in Patients with Lesions of the Brain Cortex’;16. Schizophrenia: Jaspers, K. (1959), ‘The Worlds of Schizophrenic Patients’;

Minkowski, E. (1927), ‘The Essential Disorder Underlying Schizophrenia and Schizophrenic Thought’;Binswanger, L. (1956), ‘Extravagance, Perverseness, Manneristic Behaviour and Schizophrenia’;Blankenburg, W. (1968), ‘First Steps Toward a Psychopathology of ‘Common Sense’’;Blankenburg, W. (1965), ‘On the Differential Phenomenology of Delusional Perception: A Study of an Abnormal Significant Experience’;Conrad, K. (1958), ‘Beginning Schizophrenia: Attempt for a Gestalt-Analysis of Delusion’;Rümke, H. (1948), ‘The Nuclear Symptom of Schizophrenia and the Praecox Feeling’;17. Affective disorder: Binswanger, L. (1964), ‘On the Manic Mode of Being-in-the-World’;Schneider, K. (1920), ‘The Stratification of Emotional Life and the Structure of States of Depression’;Straus, E. (1928), ‘The Experience of Time in Endogenous Depression and in the Psychopathic Depressive State’;von Gebstattel, V. (1928), ‘Compulsive Thought Relating to Time in Melancholia’;Tellenbach, H. (1982), ‘Melancholy as Endocosmogenic Psychosis’;18. Obsessive compulsive disorder: Straus, E. (1938), ‘The Pathology of Compulsion’;von Gebsattel, V. (1938), ‘The World of the Compulsive’;19. Other: Scheler, M. (1913), ‘The Psychology of So-called Compensation Hysteria and the Real Battle against Illness’;von Gebsattel, V. (1963), ‘The Meaning of Medical Practice’;Merleau-Ponty, M. (1945), ‘Cézanne’s Doubt’;Epilogue;Index.

Additional InformationLevel: clinicians, professionals, graduate students




Principles of Psychiatric GeneticsEdited by John I. Nurnberger, JrIndiana University School of Medicine

and Wade BerrettiniUniversity of Pennsylvania School of Medicine

DescriptionDisordersofbehaviorrepresentsomeofthemostcommonanddisablingdiseasesaffectinghumankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals . Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation . Principles of Psychiatric Genetics includes22disorder-basedchapterscovering,amongstotherconditions,schizophrenia,mooddisorders,anxietydisorders,Alzheimer’sdisease,learninganddevelopmentaldisorders,eatingdisordersandpersonalitydisorders . Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues . Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies .

Key Features

• Coversallmajorpsychiatricdisordersactingasa‘single-stop’forinformationonthegeneticsofthesediseases

• Summarizestheverylatestdatafromgenome-wideassociationresultsandstudiesofcopynumbervariation

• Featuresethicalandsocietalperspectivestogivereadersanappreciationofthewiderimplicationsofgeneticadvances

ContentsPreface;1. Contribution of genetic epidemiology to our understanding of psychiatric disorders;2. A basic overview of contemporary human genetic analysis strategies;3. In silico analysis strategies and resources for psychiatric genetics research;4. Gene expression studies in psychiatric disorders;5. Pharmacogenetics in psychiatry;6. Functional validation of candidate genetic susceptibility factors for major mental illnesses: from protein chemistry, cell biology, animal study, to human brain imaging;7. Epigenetic mechanisms in drug addiction and depression;8. Panic disorder;

9. The genetics of phobic disorders and generalized anxiety disorder;10. Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders;11. Post-traumatic stress disorder;12. Antisocial behavior: gene environment interplay;13. Learning disabilities;14. Autism and autism spectrum disorders;15. Genetics of major depression;16. The genetics of anorexia and bulimia nervosa;17. Genetics and common human obesity;

18. Alcoholism;19. Nicotine dependence;20. Genetics of stimulant dependence;21. Genetics of personality disorders;22. Ethical issues in behavioral genetics;23. Genetics of Tourette syndrome and related disorders;24. Endophenotypes;25. Developmental disorders;Index.


August 2012 246 x 189 mm 416pp 58 b/w illus. 21 colour illus. 978-0-521-89649-8 Hardback c. £85.00




Schizo-Obsessive DisorderMichael PoyurovskyTirat Carmel Mental Health Center, Israel

DescriptionThis is the first book to address the clinical and neurobiological interface between schizophreniaandobsessive-compulsivedisorder(OCD).Thereisgrowingevidencethatobsessive-compulsivesymptomsinschizophreniaareprevalent,persistentandcharacterizedby a distinct pattern of familial inheritance, neurocognitive deficits and brain activation . Thistextprovidesguidelinesfordifferentialdiagnosisofschizophrenicpatientswithobsessive-compulsivesymptoms,andpatientswithprimaryOCDalongsidepoorinsight,psychoticfeaturesorschizotypalpersonality.Writtenbyaleadingexpertinthecoexistenceofobsessive-compulsiveandschizophrenicphenomena,Schizo-ObsessiveDisorder uses numerous case studies to present diagnostic guidelines and to describe a recommended treatment algorithm, demystifying this complex disorder and aiding its effective management . The book is essential reading for psychiatrists, neurologists and the wider range of multidisciplinary mental health practitioners .

Key Features

• Proposesdiagnosticcriteriaandguidelinesfordifferentialdiagnosis

• Includesarecommendedtreatmentalgorithmforeffectivemanagementofpatients

• Describes50clinicalvignettes,enablinglearningfromrealclinicalexperience

ContentsForeword;Preface;1. Schizophrenia and OCD: comparative characteristics;2. Obsessive-compulsive symptoms in schizophrenia: conceptual history;3. Obsessive-compulsive symptoms in schizophrenia: epidemiological and clinical aspects;

4. Obsessive-compulsive symptoms in schizophrenia: psychopathological characteristics;5. Obsessive-compulsive symptoms in schizophrenia: prodrome;6. Obsessive-compulsive symptoms in schizophrenia: across life span;7. OCD-spectrum disorders in schizophrenia;8. Schizotypal OCD;

9. OCD with poor insight;10. Neurobiology of schizo-obsessive disorder;11. Treatment of schizophrenia with obsessive-compulsive symptoms;12. Antipsychotic drug-induced obsessive-compulsive symptoms;13. Conclusions and future directions;Index.

Additional InformationLevel: medical specialists/consultants

January 2013 234 x 156 mm 256pp 11 b/w illus. 40 tables 978-1-107-00012-4 Hardback c. £70.00




Severe Domestic SqualorJohn SnowdonUniversity of Sydney

Graeme HallidayConcord Hospital, Sydney

and Sube BanerjeeInstitute of Psychiatry, London

DescriptionShould you intervene in the life of the 48-year-old woman whose dwelling is stuffed with accumulatedrubbishandwhowillnotletanyonehelpgetridofit–orthe78-year-oldsurroundedbyputrescentfoodandfilth–orthe‘animalaccumulator’?Casesofseveredomesticsqualor(sometimescalledDiogenesSyndrome)areamongthemostcomplexanddifficultfacedbycommunityagencies.Localcouncils,housingofficers,healthprofessionals,social services, animal welfare agencies, public guardians and of course relatives and neighbours often feel powerless and lack confidence about what to do when faced with such situations . The guidelines, recommendations and case examples in SevereDomesticSqualor will help concerned people to understand what can be done and how, by providing an understanding of the causative factors and who should take the lead in dealing with them .

Key Features

• Thefirstcomprehensivebookonthistopic

• Includesdiscussiononwaysofdealingwithseveredomesticsqualorinvaryingculturesandsettingsaroundtheworld

• Coversavarietyofethicalconcernsarisingfromproposalstointerveneinsuchcases

ContentsPreface;1. Defining squalor and hoarding;2. A review of the literature on squalor;3. Hoarding: its relevance to severe domestic squalor;4. Animal hoarding;5. Assessment of squalor and hoarding;

6. Interventions in cases of squalor;7. Use of the law when intervening in cases of squalor;8. Guidelines for intervention;9. Ethics of intervention;10. There is much to be done;Appendix;Index.

Additional InformationLevel: professionals

October 2012 234 x 156 mm 240pp 50 b/w illus. 978-1-107-01272-1 Hardback c. £55.00




Cognitive Impairment in SchizophreniaCharacteristics, Assessment and Treatment

Edited by Philip HarveyUniversity of Miami

DescriptionAlthoughtheprecisemechanismsandpathwaysofschizophreniaremainsomethingofa mystery, there is little dispute that cognitive deficits present as some of the clearest and most debilitating symptoms of the disease . This book describes the characteristics ofcognitivedeficitsinschizophrenia,functionalimplications,thecourseofimpairments,the genetic and biological contributions and reviews management options, including neuropsychological, psychological and pharmacological techniques . Chapters are written by leading experts in the field, in an accessible and highly informative style, ensuring the content is clinically relevant . State-of-the-art information about new developments in the treatment of related features of the illness, such as disability, is provided . The wide ranging focus of this volume will appeal to clinicians and academic researchers working with patients impaired by severe mental illness .

Key Features

• Accessible,clinicallyrelevantwritingstyle

• State-of-the-artinformationabouteffectivepatientmanagementandcriticalresearchtopics

• Writtenbyleadingexpertsinthefield

ContentsPreface;Part I. Characteristics of Cognitive Impairment in Schizophrenia:1. Cognition in schizophrenia as a central illness feature;2. The multi-faceted, ‘global’ cognitive impairment profile in schizophrenia;3. Comparative impairments across schizophrenia and bipolar disorder;4. Cognitive impairment and symptom dimensions in psychosis;Part II. Functional Implications and Course:

5. Neurocognition and functional outcome in schizophrenia: filling in the gaps;6. Cognition and work functioning in schizophrenia;7. Cognition and functional status in adult and older patients with schizophrenia;8. Social cognition and its relationship to neurocognition;9. Cognitive functioning and awareness of illness in schizophrenia: a review and meta-analysis;Part III. Genetic and Biological Contributions to Cognitive Impairment:10. Genetic influences on cognition in schizophrenia;

11. Neurobiological determinants of cognition;12. Translational cognitive neuroscience of schizophrenia: bridging neurocognitive and computational approaches towards understanding cognitive defects;Part IV. Assessment and Treatment of Cognitive Impairment and Related Features:13. Assessment of cognition in schizophrenia treatment;14. Performance-based measures of functioning in schizophrenia;15. Pharmacological approaches to cognitive enhancement;16. Computerized cognitive training in schizophrenia: current knowledge and future directions;Index.


December 2012 234 x 156 mm 320pp 34 b/w illus. 7 colour illus. 978-1-107-01320-9 Hardback c. £60.00




Comprehensive Care for Complex PatientsThe Medical-Psychiatric Coordinating Physician Model

Steven A. FrankelUniversity of California, San Francisco

James A. BourgeoisMcMaster University, Ontario

and Philip ErdbergUniversity of California, San Francisco

Description‘Complexpatients’areasizeablepopulationwhogenerallyrequiredisproportionateattention for their management and respond poorly to treatment . Their systemic medical, psychiatric and personal needs have a tendency to drain or exceed the capabilities of those whotreatthemwhilstoverutilizinghealthcareresources.Asthispatientpopulationgrows,we move ever closer to a crisis in health care delivery . This volume presents an innovative team-based approach for assessing and managing diagnostically complex and management intensive patients . The physician-led ‘Medical-Psychiatric Coordinating Physician (MPCP)’ model not only improves patient treatment, but also provides for the containment of costs by reducing redundancy and curbing excess in the use of services . Other benefits include improved diagnostic accuracy and decision making, as well as better communication among physicians and allied health professionals . This book is essential reading for psychiatrists, primary care physicians, and physicians, directors and administrators working in multidisciplinary specialty clinics .

Key Features

• Guidelinesfacilitatetheeffectiveidentification,assessmentandtreatmentofclinicallycomplexpatientswithmixedpsychiatricand systemic medical illnesses

• Systematicandpracticalpresentationofaninnovativemodelcreatedspecificallyfortreatingthesepatients

• Outcomesincludeimprovedcaseretentionandsymptomresolution,lesswastedresourcesandoverutilizationofservicesandgreater patient satisfaction

ContentsPreface;Foreword;Part I. Introduction:1. Clinical complexity: the evolving place for a medical-psychiatric coordinating physician;2. Beyond the physician-patient model: the value of a treatment team for dealing with clinical complexity;Part II. Guidance for Negotiating Clinical Complexity:

3. Sorting out clinical complexity: medical and psychometric testing;4. The limitations of algorithms: details of two clinically complex treatments;5. Negotiating the subjectivity and inter-subjectivity of the clinical field: the complexity inherent in clinical work;Part III. Clinical Decisions and their Execution: Accuracy Within Complexity:6. The intersection of data and clinical judgment: the place of subjectivity in treatment decisions;7. Clinical strategy: grappling with treatment complexity;

8. Working consensus: the importance of physician-patient collaboration;9. Linking truing measures: technical and interpersonal precision in work with complex cases;Part IV. The Application of the Model: The Medical-Psychiatric Coordinating Physician:10. Managing complex treatments: the medical-psychiatric coordinating physician;11. The medical-psychiatric coordinating physician model: its components, costs, and future;Bibliography;Index.





29Neurology and clinical neuroscience

Case Studies in Neurological PainClaudia SommerUniversität Würzburg, Germany

and Douglas ZochodneUniversity of Calgary

DescriptionPain is one of the most common symptoms of neurological disease and its appropriate management is essential to the effective care of patients . Neurological disorders differ in their specific pain phenotype, mechanisms and therapy . Case Studies in Neurological Pain addresses the specific pain issues, treatment and pathophysiology in patients with awidespectrumofneurologicaldisease.Clinicalcasestudieshavelongbeenrecognizedas a useful adjunct to problem-based learning and continuing professional development . Theyemphasizetheneedforclinicalreasoning,integrativethinking,problem-solving,communication,teamworkandself-directedlearning–alldesirablegenericskillsforhealthcareprofessionals.Presentingreal-lifecases–coveringconditionsincludingdiabeticandidiopathicpolyneuropathies,focalneuropathies,multiplesclerosisandheadachedisorders–thisbookprovidesneurologists,neurosurgeons, pain clinic specialists and primary care physicians with an understanding of problems encountered in neurological practice . There are also chapters on mechanisms of neurological pain and new treatment guidelines .

Key Features

• Includesrecommendedtreatmentplanstoaidquickandaccuratetreatment

• Real-lifecasesfacilitateunderstandingofthepatient’sproblemsmoreaccuratelythandatafromclinicaltrials

• Discussesmechanismsofpainandtherapeuticchallengestoguideresearchersandindustryintheirapproachtonewtherapies

ContentsPreface;Part I. The Biology of Neuropathic Pain:1. Mechanisms of neuropathic pain;Part II. Focal, or Localized Neuropathies:2. Pain in carpal tunnel syndrome;3. Pain and cervical radiculopathy;4. Pain and diabetic lumbosacral plexopathy;5. Pain and meralgia paraesthetica;6. Pain and lyme radiculopathy (Borrelia-associated radiculitis);7. Neuralgic amyotrophy;8. Painful radiculopathy associated with herpes zoster infection;Part III. Generalized neuropathies or polyneuropathies:9. Pain and chronic inflammatory demyelinating polyneuropathy;

10. Pain and diabetic polyneuropathy (DPN);11. Painful idiopathic polyneuropathy;12. Pain in vasculitic neuropathy;13. Painful polyneuropathy associated with anti-MAG autoantibodies;14. Painful polyneuropathy associated with inherited amyloidosis;15. Small fiber neuropathy in sarcoidosis;16. Pain and small fiber polyneuropathy in Fabry disease;Part IV. Other Neuromuscular and Neurological Disorders:17. Pain and proximal myotonic myopathy (DM2);18. Complex regional pain syndrome;19. Pain and polymyalgia rheumatica;20. Phantom pain;Part V. CNS Disorders:21. Pain in Parkinson’s disease;

22. Pain associated with amyotrophic lateral sclerosis (ALS);23. Pain in Brown–Séquard syndrome;24. Pain in syringomyelia;25. Central pain with thalamic infarct;26. Pain in multiple sclerosis;Part VI. Headache Disorders:27. Chronic migraine;28. Cluster headache;29. Paroxysmal hemicrania;30. Trigeminal neuralgia;31. Headache and acute cerebral ischemia;Part VII. Treatment:32. Therapeutics in neuropathic pain;Index.

Additional InformationLevel: clinicians

December 2012 246 x 189 mm 166pp 30 b/w illus. 28 colour illus. 978-0-521-69526-8 Paperback c. £40.00



30 Neurology and clinical neuroscience

The Biology of Multiple SclerosisGregory AtkinsTrinity College, Dublin

Sandra AmorV U Medical Center, Amsterdam

Jean FletcherTrinity College, Dublin

and Kingston MillsTrinity College, Dublin

DescriptionMultiple sclerosis is the most common debilitating neurological disease in people under the age of forty in the developed world . Many publications cover medical and clinical approaches to the disease; however, TheBiologyofMultipleSclerosis provides a clear and concise up-to-date overview of the scientific literature on the various theories of MS pathogenesis . Covering the main elements of scientific research into multiple sclerosis, the book contains chapters on the neuropathology of the disease as well as an account of the most extensively used animal model experimental autoimmune encephalomyelitis . The book contains chapters regarding the role of viruses in the development of multiple sclerosis . Viruses have long been implicated and chapters on animal models based on virus infection, as well as their possible role in the etiology of MS, are included . Of interest to MS researchers, the book is written to also be of value to postgraduate and medical students .

Key Features

• Writtentobeaccessibletopostgraduatestudentsaswellasresearchers

• Providesthefirstoverviewofthebiologicalaspectsofmultiplesclerosis

• Summaryoftheextensiveresearchintomultiplesclerosisundertakeninrecentyears

Contents1. Introduction: the biological basis;2. Neuropathology of multiple sclerosis;3. Experimental autoimmune encephalomyelitis;4. Immunology of MS;5. Animal models based on virus infection;6. Viruses in the etiology of MS;7. Epilogue: conclusions and future directions.

Additional InformationLevel: academic researchers, medical students

December 2012 234 x 156 mm 152pp 29 b/w illus. 4 colour illus. 978-0-521-19680-2 Hardback c. £50.00




Sleep Deprivation, Stimulant Medications, and CognitionEdited by Nancy J. WesenstenDepartment of Behavioral Biology, Walter Reed Army Institute of Research, Silver Spring, MD, USA

DescriptionSleepDeprivation:StimulantMedicationsandCognition provides a review, synthesis and analysis of the scientific literature concerning stimulant medications and neurobehavioral performance, with an emphasis on critically evaluating the practical utility of these agents for maintaining cognitive performance and alertness in sleep-deprived (but otherwise healthy) individuals . The book explores the nature of sleep loss-induced cognitive deficits, neurophysiologic basis of these deficits, relative efficacy and limitations of various interventions (including non-pharmacological), and implications for applying these interventions in operational environments (commercial and military) . Readers of this volume will gain a working knowledge of: •Mechanismscontributingtosleeploss-inducedcognitivedeficits •Differentialeffectsofstimulantcompoundsonvariousaspectsofcognition •Considerations(suchasabuseliability)whenapplyingstimulantinterventionsinoperationalsettings •Currentstateandfuturedirectionsforincludingstimulantsincomprehensivefatigue-managementstrategies. This text is key reading for researchers and trainees in sleep and psychopharmacology .

Key Features

• Includesin-depthreviewsofmodafinilandcaffeine’seffectsoncognitiveperformanceundervarioussleep-lossscenarios

• Providesreviewsofalternativestostimulants(suchasslow-wavesleepenhancement)formaintainingcognitiveperformance

• Containsanin-depth,evidence-basedreviewofstimulantabuseliabilityanduseofstimulantsfor‘cognitiveenhancement’undernon-sleep-deprived conditions

• Facilitateshead-to-headcomparisonsofdifferentstimulantsandinterventions

• Provides‘one-stopshopping’forin-depthinformationonstimulanteffectsoncognition

ContentsForeword: sustaining cognitive performance: a modern imperative;Part I. Basic Mechanisms: Cognitive Performance and Sleep:1. The true nature of sleep loss-Induced ‘neurocognitive performance deficits’ – a critical appraisal;2. Using fMRI to study cognitive function and its modulation in sleep deprived persons – a selective overview;3. The neurochemistry of cognitive impairment following sleep loss;4. The genetic basis of individual vulnerability to sleep loss;Part II. Stimulant Reversal of Cognitive Deficits:

5. Modafinil reversal of cognitive deficits during sleep loss;6. Utility of caffeine: evidence from the laboratory;7. Caffeine: mechanism of action, genetics and behavioural studies conducted in task simulators and the field;8. Stimulants in models of shift work and shift work disorder;9. The potential for abuse of stimulants in chronically sleep-restricted populations;10. Cognition enhancers versus stimulants;11. Novel pathways for stimulant development: the histaminergic system;12. Novel pathways for stimulant development: the hypocretin/orexin system;

Part III. Alternatives for Sustaining Cognitive Performance During Sleep Loss:13. Light exposure for improving cognition during sleep loss and circadian misalignment;14. Nutritional countermeasures for cognitive performance decrements following sleep deprivation;15. The role of alertness monitoring in sustaining cognition during sleep loss;16. Sustaining neurobehavioral performance on less sleep: is SWS enhancement the key?;Part IV. Summary and Conclusions:17. Use of stimulants in operational settings: issues and considerations;18. Fatigue management: the art of the state.

Additional InformationLevel: medical specialists/consultants, academic researchers

August 2012 246 x 189 mm 296pp 63 b/w illus. 11 colour illus. 35 tables 978-1-107-00409-2 Hardback c. £70.00




Case Studies in Polysomnography InterpretationEdited by Robert C. BasnerPulmonary, Critical Care, and Allergy Division, Columbia University College of Physicians and Surgeons, New York

DescriptionThe polysomnogram is a formidable sleep medicine tool, typically incorporating multiple channels of physiologic data including EEG, ECG, EMG, respiratory flow and effort, ventilation via CO2 monitoring, oxygen saturation via pulse oximetry and ventilatory treatment modalities . Aspiring experts must constantly ask themselves questions regarding PSGinterpretationsuchas:AmIconfidentinusingallofthesemodalities?CanIaccuratelyandconsistentlydistinguishaseizurefromamovementdisorder;aservoventilatorsignalfromanauto-titratingcontinuouspositiveairwaypressuresignal;anepisodeofCheyne–Stokesbreathingfromanepisodeofobstructivesleepapnea?Theauthorstakeyouinto their own sleep laboratories and deliver real-life cases for you to interpret with them . Such expertise is vitally useful for house staffandfellowslearningsleepmedicine,thoseseekingBoardcertification,technologistswhoscorePSGsandseasonedsleepcliniciansmanagingpatientswithsleep-relatedhealthdisorders.EveryimagefeaturesontheaccompanyingCD-ROM.

Key Features

• Aself-testingformatwhereeachcasefollowsacommonformat,includingabriefclinicalhistoryandmultiplepossibleinterpretations followed by questions regarding the possible diagnoses

• AllimagesareincludedontheaccompanyingCD-ROM

• Over100challengingcasestudiesandpolysomnogram(PSG)tracings,selectedbymorethan30internationalsleepexpertsandmasters in polysomnogram interpretation




ContentsPreface;List of abbreviations;1. A 74-year-old man with severe ischemic cardiomyopathy and atrial fibrillation;2. A 65-year-old man with amyotrophic lateral sclerosis;3. An 80-year-old man with severe heart failure and witnessed apnea awake and during sleep;4. A 33-year-old man with a history of interstitial pulmonary fibrosis and obesity;5. A 52-year-old man being treated for sleep-related hypoventilation;6. An 81-year-old obese woman with a history of snoring;7. A 33-year-old obese man with idiopathic pulmonary fibrosis and snoring;8. A 57-year-old woman with moderate obstructive sleep apnea;9. A 57-year-old woman with potential obstructive sleep apnea;10. An 80-year-old man with heart failure and previously documented Cheyne–Stokes breathing;11. A 46-year-old obese man with loud snoring, witnessed apnea, and daytime sleepiness;12. A 60-year-old woman with severe obstructive sleep apnea;13. A 52-year-old man with valvular cardiomyopathy;14. An otherwise healthy 40-year-old man with potential obstructive sleep apnea;15. A 32-year-old man with observed severe snoring, and leg shaking during sleep;16. A 20-year-old woman with extreme sleepiness who reports hypnic hallucinations, sleep paralysis, and sudden loss of muscle tone when startled;17. A 67-year-old man with chronic sleep-onset problems and maintenance insomnia, as well as episodes of talking and walking in his sleep;18. A 77-year-old woman with sudden episodes of loss of consciousness;19. A 32-year-old woman with frequent nocturnal episodes of sudden arousal and short chaotic movements;20. A 70-year-old woman with a history of hypertension and paroxysmal atrial fibrillation;21. A 74-year-old man with known cardiac disease, with an automated implantable cardioverter–defibrillator;22. A 60-year-old man with known coronary artery disease;23. A 38-year-old man with ‘restlessness’ at night prior to sleep onset;24. A 50-year-old previously healthy man with obstructive sleep apnea and a recent history of palpitations;25. A 53-year-old man with a history of loud snoring and daytime sleepiness;26. A 27-year-old man with a 10-year history of

33. A 24-year-old woman with a history of anxiety, asthma, and daytime sleepiness;34. A 43-year-old Chinese man with a history of obesity, difficult-to-control hypertension, and proteinuria has daytime sleepiness and snoring;35. A 57-year-old man with a history of mild dyslipidemia who had a cerebrovascular accident several months earlier;36. A 29-year-old man who is mildly overweight, with a history of depression and attention deficit hyperactivity disorder, with difficulty falling asleep and daytime sleepiness;37. Findings in a polysomnogram;38. A 29-year-old man assessed for a diagnosis of narcolepsy;39. A 24-year-old man with symptoms of excessive daytime sleepiness;40. A 43-year-old obese man with a history of snoring;41. A maintenance of wakefulness test;42. Assessment of a sleep stage;43. Analysis of a precordial ECG finding;44. Linkage of episodes of gastroesophageal reflux with polysomnogram epochs;45. Polysomnography findings in fibromyalgia;46. A 45-year-old man presents with newly diagnosed hypertension and symptoms of snoring;47. A 10-year-old child with central congenital hypoventilation syndrome;48. A 9-year-old child with asthma, skeletal dysplasia, restrictive lung disease and obstructive sleep apnea;49. A 21-year-old man with a history of significant daytime sleepiness;50. A 58-year-old woman taking fentanyl and tramadol and with witnessed pauses in breathing;51. A 37-year-old woman with bipolar disorder and a recent head injury;52. A 12-year-old boy with a history of refractory seizures;53. An 8-year-old boy with snoring and poor sleep;54. A 30-week premature infant with snoring and poor sleep at 17 months of age;55. A 75-year-old man with a history of excessive daytime sleepiness, generalized body ‘weakness’ with excitement, surprise, and anger;56. An 18-year-old woman with a 2-year history of being a ‘late sleeper’;57. An otherwise healthy 9-year-old boy who falls asleep in school;58. A 35-year-old woman who is 6 months’ pregnant and has a history of snoring with pauses in breathing;59. A 22-year-old graduate student with daytime tiredness;60. Interpretation of traces from

68. A 25-year-old morbidly obese man with loud snoring and excessive daytime sleepiness;69. A 55-year-old man with snoring and excessive daytime sleepiness;70. A 61-year-old woman with loud snoring and daytime sleepiness;71. A 50-year-old woman with a complaint of daytime sleepiness;72. A 50-year-old obese man with a history of left ventricular failure and witnessed apnea;73. A 34-year-old man with snoring and excessive sleepiness;74. A 55-year-old man with a T11 spinal cord injury and paraplegia in association with metastatic disease complaining of daytime sleepiness;75. A 62-year-old woman with potential obstructive sleep apnea;76. A 64-year-old morbidly obese man with severe chronic obstructive pulmonary disease and severe obstructive sleep apnea;77. A 30-year-old woman with a diagnosis of moderate obstructive sleep apnea;78. A 75-year-old man with difficulties in initiating sleep and fragmented restless sleep;79. A 4-year-old girl with mild developmental delay and a history of confusion and abnormal night-time movements of her extremities;80. A 30-year-old woman with several years of making noises at night and feeling tired;81. A 35-year-old man with excessive movement of his legs during sleep;82. A 16-year-old girl with episodes of yelling, crying and laughing during sleep;83. A 25-year-old woman who bites her tongue during sleep;84. A 70-year-old man with abnormal night-time behavior, resulting in falls from the bed;85. A 6-year-old girl with enlarged tonsils and adenoids and a history of snoring and gasping at night;86. A 12-year-old boy with excessive daytime sleepiness;87. A 62-year-old man with congestive heart failure undergoing continuous positive airway pressure titration for obstructive sleep apnea;88. A 54-year-old morbidly obese man with a history of congestive heart failure complaining of loud snoring, excessive daytime sleepiness, fatigue, and nocturia;89. A 53-year-old man with history of central sleep apnea and congestive heart failure;90. A 33-year-old morbidly obese man with obesity-hypoventilation syndrome;91. A 62-year-old man with chronic obstructive pulmonary disease and obstructive sleep apnea;92. A 56-year-old woman who smokes and is obese;93. A 76-year-old man with exertional dyspnea, orthopnea and excessive daytime sleepiness;


September 2012 276 x 219 mm 176pp 164 colour illus. 978-1-107-01539-5 Hardback c. £75.00



The Behavioral and Cognitive Neurology of StrokeSecond edition

Edited by Olivier GodefroyDepartment of Neurology, Amiens University Hospital

DescriptionThe ever-improving emergency care of those who have suffered serious cerebrovascular disease has shifted the treatment objective towards helping sufferers regain independence –meaningthatthereisanincreasedneedtounderstand,manageandtreattheresidualdeficits . TheBehavioralandCognitiveNeurologyofStroke focuses on the diagnosis and management of behavioral and cognitive problems in patients with cerebrovascular disease . Written to be practical for clinical use, the book contains diagnosis and management strategies for all disorders observed in stroke patients, including acute and later problems, andaimingtominimizelong-termdisability.Allimportantinformationrelatedtoeachdisorderissummarizedinkey-pointtables.Fullyupdatedthroughoutandcontainingfivenewchapters,thisneweditionbringsthebookuptodatewiththemajoradvancesof the last five years . This book will be of value to all clinicians caring for stroke patients, neuroscientists, neuropsychologists, neurorehabilitationists and a wide range of therapists .

Key Features

• Majorrevisionofsuccessfultitlewithnewfocusonvascularcognitiveimpairment

• Comprehensive,focusingondiagnosisandmanagement–offerspracticalpatientmanagementguidelines

• Alsocoverslong-termdisabilitypost-strokeandneurorehabilitation

ContentsPreface;Part I. Vascular Cognitive Impairment:1. Introduction: what is vascular cognitive impairment?;2. Vascular cognitive impairment in the memory clinic;3. Vascular cognitive impairment in the stroke unit and after the acute stage;Part II. Analytic Approach: The Behavioral and Cognitive Neurology of Stroke:4. Cognitive and behavioral disorders according to stroke site and side;Section 1. Motor and Gestural Disorders:5. Movement and gestural disorders: abnormal movement and motor behavior;6. Limb apraxia: a disorder of gesturing and object use;Section 2. Aphasic, Arthric, Calculation, and Auditory Disorders:7. Vascular aphasias;8. Dysarthria;9. Alexia and agraphia in acute chronic stroke;

10. Acalculia;11. Auditory disorders related to strokes;Section 3. Hemineglect, Anton-Babinski, and Right Hemisphere Syndromes:12. Hemispatial neglect;13. Anosognosia and denial after right hemisphere stroke;14. Asomatognosia: disorders of the bodily self;15. Disorders of visuoconstructive ability;16. Topographical disorientation;Section 4. Visual Agnosia and Balint’s Syndrome:17. Cortical blindness;18. Balint’s syndrome;19. Prosopagnosia;20. Object and color agnosia;Section 5. Executive and Memory Disorders:

21. Dysexecutive syndromes;22. Disorders of episodic memory;23. Working memory dysfunction in stroke patients;Section 6. Behavioral and Mood Disorders:24. Alterations of level of consciousness related to stroke;25. Akinetic mutism and related disorders;26. Delirium and confusional state in stroke patients;27. Delusion, mania and personality changes;28. Depression after stroke and cerebrovascular disease;29. Fatigue after stroke;Part III. Dementia and Management of Vascular Cognitive Impairment:30. Vascular dementia;31. Cognitive and behavioral assessment of vascular cognitive impairment;32. Treatment of patients with post-stroke dementia;Index.


January 2013 246 x 189 mm 496pp 109 b/w illus. 18 colour illus. 978-1-107-01557-9 Hardback c. £95.00

EDITED BY Olivier Godefroy

SECOND EDIT ION

The Behavioral and Cognitive

Neurology of Stroke




Sleep, Stroke and Cardiovascular DiseaseEdited by Antonio CulebrasDepartment of Neurology, Upstate Medical University, Syracuse, NY

DescriptionTherelationshipbetweensleepdisorders–inparticularsleepapnea,ahighlyprevalentcondition–andcommonvasculardisturbancessuchasstrokeandhypertensionisanareaofactiveresearch.Summarizingtheclinicalevidencetodatebetweensleepdisordersandvascularpathology, this is the first time a comprehensive overview of this relationship has been covered in asinglevolume.Bringingtogethersomeoftheworld’smostrenownedauthorsinthefield,Sleep, StrokeandCardiovascularDiseasecontainsrecommendedtreatmentplans–allowingforrapidandaccuratediagnosisandmanagementofpatients–enablinglearningfromrealexperience.Ofinterest, not only, to specialists who intervene in diagnosis and management of sleep and stroke disorders such as neurologists, cardiologists and pulmonologists, the book will also be of value to primary-care practitioners, allowing them to arrive at better diagnoses and management of sleep and vascular disorders .

Key Features

• Providessummaryoftheclinicalevidencelinkingsleepdisordersandvascularpathology

• Casestudiesallowlearningfromrealexperience

• Writtenbyworld-leadingresearchers

ContentsPreface;1. Overview of sleep and stroke;2. Sleep apnea, oxidative stress, pro-inflammatory vascular risk factors and endothelial disease;3. Sleep apnea, autonomic dysfunction and vascular diseases;4. Sleep apnea and hypertension: a clinical perspective;5. Sleep apnea, stroke risk factors and the arousal response;6. Sleep apnea and atrial fibrillation;

7. Patent foramen ovale, obstructive sleep apnea and its relation to ischemic stroke;8. Pathogenesis of cerebral small-vessel disease in obstructive sleep apnea;9. Sleep apnea and acute stroke deterioration;10. Effect of CPAP on stroke risk factors and stroke;11. Rehabilitation of stroke and sleep apnea;12. Restless legs syndrome, periodic limb movements in sleep and vascular risk factors;13. Physician as patient: a personal story of stroke;Index.


December 2012 234 x 156 mm 184pp 26 b/w illus. 5 tables 978-1-107-01641-5 Hardback c. £50.00

Sleep, Stroke and Cardiovascular DiseaseEdited by Antonio Culebras



36 Obstetrics and gynecology, reproductive medicine

Textbook of Clinical EmbryologyEdited by Kevin Cowardand Dagan Wells

DescriptionThe success of Assisted Reproductive Technology is critically dependent upon the use of welloptimizedprotocols,baseduponsoundscientificreasoning,empiricalobservationsand evidence of clinical efficacy . Recently, the treatment of infertility has experienced arevolution,withtheroutineadoptionofincreasinglyspecializedmolecularbiologicaltechniques and advanced methods for the manipulation of gametes and embryos . This textbook–inspiredbythepostgraduatedegreeprogramattheUniversityofOxford–guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance,andfromendocrinologytomolecularbiologyandresearchmethods.WrittenforalllevelsofIVFpractitioners,reproductivebiologistsandtechnologistsinvolvedinhumanreproductivescience,itcanbeusedasareferencemanualforallIVFlabsandasatextbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology .

Key Features

• Addressesclinicalpracticeandalsotheunderlyingscience

• Comprehensive–coversallthatstudentsinthistopicrequireforpostgraduatequalificationsandre-accreditation

• Wellillustrated,includingvideocontentofkeyprocedures

ContentsPreface;Part I. Mammalian Reproductive Physiology:1. Sexual reproduction: an overview;2. Sexual development;3. Male reproductive tract and spermatogenesis;4. Female reproductive tract and oogenesis;5. The menstrual cycle and ovulation;6. Early oocyte growth;7. Regulation of gonadal function;8. Reproductive endocrinology;9. Reproductive immunology;10. Sperm biology and maturation;11. Fertilization and egg activation;

12. Early embryogenesis;13. Human organogenesis;Part II. Infertility:14. Global perspectives in reproductive health and fertility;15. Fertility control and contraception;16. Fertility assessment, evaluation and treatment;17. Male, female and unexplained infertility;18. Social and cultural aspects of infertility;Part III. Assisted Reproductive Technology (ART):19. Overview and history of ART;20. Legal, ethical and regulatory aspects of ART;21. Quality control, management and iso-accreditation;22. Regulation and the Human Embryology and Fertilization Authority;Part IV. Assisted Reproductive Technology: Skills, Techniques and Present Status:

23. Fundamental laboratory skills for clinical embryologists;24. Sperm analysis and preparation;25. Superovulation protocols;26. Intra-cytoplasmic sperm injection (ICSI);27. Embryo culture;28. Embryo biopsy;29. In vitro maturation of oocytes;30. Assessing oocyte and embryo quality;31. Cryopreservation of gametes and embryos;32. Reproductive surgery;33. Pre-implantation genetic diagnosis (PGD);34. Pre-implantation genetic screening and comparative genome hybridisation (CGH);35. Embryonic stem cell biology;36. Current issues and developments in medical ethics.

Additional Resources:http://www.cambridge.org/9780521166409 CD-ROM


February 2013 246 x 189 mm 288pp 978-0-521-16640-9 Paperback c. £49.00



37Obstetrics and gynecology, reproductive medicine

Obstetric and Intrapartum EmergenciesA Practical Guide to Management

Edited by Edwin ChandraharanSt George’s University of London

and Sabaratnam ArulkumaranSt George’s University of London

DescriptionEvery day, approximately 1000 women die from preventable causes related to pregnancy and childbirth, most of which result from common treatable complications, such as haemorrhage, infections, pre-eclampsia and obstructed labour, which have not been recognizedintimeortreatedproperly.Everyunbornchildalsofacesriskofstillbirth,birthtrauma, oxygen deprivation and neonatal death or long-term brain damage during birthing . Obstetric and Intrapartum Emergencies: A Practical Guide to Management is written by a wide variety of obstetric experts in developing and developed countries and providesaneasy-to-useguidetorecognizeandtreatperinatalemergenciesbeforeitistoolate.Thetextincludeslearningtoolssuchas ‘Key Pearls’ and ‘Key Pitfalls,’ a section on managing emergencies in a low-resource setting and contains detailed illustrations throughout . This book is a practical and invaluable guide for obstetricians, neonatologists, midwives, medical students and the wider perinatal team .

Key Features

• Numerousflowcharts,photographsandillustrations

• Coversemergenciesinallsituations–lowandhighresourcesettingsandincludessectionsonsimulationtrainingandfiredrills

• Containsevidence-basedmanagementguidelinesforemergenciesclinicianswillencounter

ContentsPart I. General Principles:1. Anatomic and physiologic changes during pregnancy;2. Principles of resuscitation for maternal collapse;Part II. Algorithms for Management of the Top Five ‘Direct Killers’:3. Deep-vein thrombosis and pulmonary embolism;4. Severe pre-eclampsia and eclampsia;5. Massive obstetric hemorrhage;6. Septicemia and septic shock;7. Amniotic fluid embolus;Part III. Intrapartum Emergencies:8. Uterine rupture;9. Breech delivery;10. Umbilical cord prolapse;11. Fetal compromise: diagnosis and management;12. Shoulder dystocia;13. Twin delivery;

14. Instrumental vaginal delivery;15. Emergency Cesarean section;16. Unintended trauma during Cesarean section;Part IV. Postpartum Emergencies:17. Acute puerperal uterine inversion;18. Sudden postpartum maternal collapse;19. Retained placenta;20. Perineal trauma;Part V. Medical and Surgical Emergencies During Pregnancy:21. Chest pain and palpitations in pregnancy;22. Breathlessness;23. Acute abdomen;24. Blurring of vision and sudden loss of vision;25. Psychiatric emergencies;26. Drug overdose;27. Diabetic ketoacidosis in pregnancy;

28. Convulsions and epilepsy;29. Musculoskeletal considerations in pregnancy;30. Endocrine emergencies in pregnancy;Part VI. Anesthetic Emergencies:31. General anesthesia and failed intubation;32. Fluid underload and overload;33. Transfusion and anaphylactic and drug reactions;34. Major trauma including RTAs;Part VII. Neonatal Emergencies and Resuscitation:35. Neonatal emergencies and resuscitation;Part VIII. Management of Anticipated and Non-anticipated Emergencies:36. Morbidly adherent placentae;37. Peri- and post-mortem Cesarean section;Part IX. Setting-up Skills and Drills Training in Maternity Services:38. Labor ward ‘fire drills’;39. Simulation training;40. Risk-management.


October 2012 246 x 189 mm 288pp 978-0-521-26827-1 Paperback c. £45.00



38 Obstetrics and gynecology, reproductive medicine

Fetal TherapyScientific Basis and Critical Appraisal of Clinical Benefits

Edited by Mark D. KilbyDepartment of Fetal Medicine, University of Birmingham

Anthony JohnsonBaylor College of Medicine, Texas

and Dick OepkesDepartment of Obstetrics, Leiden University Medical Center

DescriptionFetaltreatment,particularlycomplexfetaltherapy,isanemergentandexpandingfield.This comprehensive text focuses on areas of fetal disease and pathophysiology that canbetreatedinuteroandthebenefitsandproblemswithsuchtherapy.Bothmedical(non-invasive) and surgical procedures are discussed, drawing on the expertise of an internationally renowned author team . Each chapter includes a comprehensive overview of the basic science underlying fetal pathology, as well as discussing the highest level of technical performance of fetal interventions . Contributions from fetal therapy ‘centers-of-excellence’aroundtheworldcollectivelyemphasizetheneedforanevidence-basedapproachtothefield.Thisvolumeisuseful both as a quick reference guide to the latest fetal therapy options and as an in-depth study book for maternal-fetal medicine and neonatology specialists at any stage of their career who are seeking to acquire essential background knowledge . Indispensable on any bookshelf in fetal medicine units .

Key Features

• Expertsinthefieldsharereliable,state-of-the-artknowledge

• Chaptersincludecriticalappraisal,helpingreadersunderstandthebasicscienceandpathogenesisoftheconditionandhowthisinfluences fetal therapy choices

• Abroadinternationalauthorshipensuresthecontentisstate-of-the-artandvaluabletoaninternationalreadership



39Obstetrics and gynecology, reproductive medicine

ContentsPreface;Foreword;Part I. General Principles:1. The rationale for fetal therapy;2. Insights into pathogenesis of adult cardiovascular disease from fetal animal studies;3. Human embryology: molecular mechanisms of embryonic disease;4. Ethics of fetal therapy;5. Fetal therapy choices: about risks, emotions, and the doctor’s role in the decision making process;Part II. Fetal Disease: Pathogenesis and Principles:6. Red cell alloimmunization: immunobiology, clinical disease, and management;7. Fetal and neonatal alloimmune thrombocytopenia;8.1. Fetal dysrhythmias: the effects of antiarrhythmic therapy on the immature heart;8.2. Fetal dysrhythmias: clinical management;9.1. Structural heart disease: embryology;9.2. Structural heart disease: genetic influences;

9.3. Structural heart disease: fetal cardiac interventions;10.1. Manipulation of amniotic fluid volume: homeostasis of fluid volumes in the amniotic cavity;10.2. Manipulation of amniotic fluid volume: oligohydramnios and polyhydramnios;11.1. Twin-to-twin transfusion syndrome: scientific basis;11.2. Twin-to-twin transfusion syndrome: placental circulation;11.3. Twin-to-twin transfusion syndrome: cardiovascular manifestations;11.4. Twin-to-twin transfusion syndrome: treatment by fetoscopic laser ablation;11.5. Twin-to-twin transfusion syndrome: management of stage I disease;12.1. Twin reverse arterial perfusion (TRAP) sequence: pathophysiology;12.2. Twin reverse arterial perfusion (TRAP) sequence: in-utero treatment;13.1. Fetal infections: fetal immune responses to congenital infections;13.2. Fetal infections: clinical management;14.1. Fetal urinary tract obstruction: pathophysiology;14.2. Fetal urinary tract obstruction: prenatal assessment and prognosis;14.3. Fetal urinary tract obstruction: fetal cystoscopy;14.4. Fetal urinary tract obstruction: in-utero intervention;

15.1. Fetal lung growth, development and lung fluid: physiology and pathophysiology;15.2. Fetal lung growth, development, and lung fluid: clinical management of pleural effusion and pulmonary pathology;16.1. Neural tube defects: pathophysiology and prevention;16.2. Neural tube defects: clinical management;17.1. Fetal tumors: pathophysiology;17.2. Fetal tumors: clinical management;18.1. Intrauterine growth restriction: placental basis and implications for clinical practice;18.2. Intrauterine growth restriction: differential diagnosis and management;19.1. Congenital diaphragmatic hernia: pathophysiology;19.2. Congenital diaphragmatic hernia: clinical antenatal management;20.1. Fetal stem cell transplantation: stem cell biology basics;20.2. Fetal stem cell transplantation: clinical potential;20.3. Fetal stem cell transplantation: fetal tissue engineering;21. Gene therapy: physiological principles and clinical potential;22. The future: fetal therapies and translation studies: global alignment, coordination and collaboration in perinatal research: The Global Obstetrics Network (GONet) initiative;Index.


November 2012 276 x 219 mm 448pp 88 b/w illus. 76 colour illus. 978-1-107-01213-4 Hardback c. £150.00


40 Pediatrics and child health

Pediatric Emergency and Critical Care UltrasoundEdited by Stephanie DonigerChildren’s Hospital and Research Center, Oakland

DescriptionEmergency bedside ultrasound assessment is well established for adult patients, but has only recently been introduced into everyday clinical practice for the care of pediatric patients . PediatricEmergencyandCriticalCareUltrasound is a concise, practical text which explains the principles of ultrasound, its diagnostic application in all organ systems and its use as aproceduraladjunct.Bothwell-establishedandinnovativeapplicationsaredescribed,assisting the practitioner in incorporating ultrasound into daily practice, facilitating patient care and decreasing radiation exposure . Case studies and abundant illustrations enable the reader to study the appropriate techniques in detail and learn from real examples from the pediatric emergency department and intensive care unit . PediatricEmergencyandCriticalCareUltrasound is the first comprehensive bedside ultrasonography resource focusing on pediatric patients and is essential reading not only for pediatric emergency medicine subspecialists but for all emergency physicians, intensivists/critical care physicians and pediatricians .

Key Features

• Thefirstcomprehensivetextbookforpediatricbedsideultrasound

• Illustrationsandimagesdepicttechniques,facilitatinglearningofbedsideultrasonography

• Casestudiesdescribecommonpediatric-specificapplications,enablinglearningfromexamplesofrealpediatricpatients

• Writtenandeditedbyworld-renownedexpertsandpioneersinbothemergencyultrasoundandpediatricemergencyultrasound

ContentsPreface;Part I. US Fundamentals:1. Ultrasound fundamentals;2. Getting started and credentialing;3. Ultrasound in austere environments;Part II. Diagnostic Ultrasound:4. E-Fast;5. Cardiac;6. Pulmonary ultrasound;

7. IVC and aorta assessment;8. EENT;9. Renal and bladder;10. Pediatric abdomen;11. Hepatic and gallbladder;12. Male genitourinary;13. Gynecology;14. Obstetrics;Part III. Procedural Ultrasound:

15. Vascular access;16. Bladder volume calculation and bladder catheterization;17. Lumbar puncture;18. Soft tissue;19. Orthopedics;20. Nerve blocks;21. Thoracentesis/paracentesis;22. Bedside ultrasound in the NICU;Index.


September 2012 276 x 219 mm 450pp 525 colour illus. 25 tables 978-0-521-18825-8 Paperback c. £65.00



41Surgery

Medical Management of the Surgical PatientA Textbook of Perioperative MedicineFifth edition

Edited by Michael LubinEmory University, Atlanta

Thomas DodsonEmory University, Atlanta

and Neil WinawerEmory University, Atlanta

DescriptionNow in its fifth edition, Medical Management of the Surgical Patient: A Textbook of Perioperative Medicine has been fully revised and updated and continues to provide an authoritative account of all aspects of perioperative care for surgical patients . Including recommended plans which aid accurate treatment of patients, it provides an evidence-based approach for consulting physicians to care for patients with underlying medical conditions that will affect their surgical management . The latest minimally invasive surgical techniques are included, with new chapters on thoracic aortic disease, reconstruction after cancer ablation, lung transplantation, esophagomyotomy, vasectomy and thyroid malignancies, amongst others . With detailed descriptions of nearly one-hundred operations, highlighting their usual course as well as their common complications, the book encourages learning from experience . This definitive account includes numerous contributions from leading experts at national centers of excellence . It will continue to serve as a significant reference work for internists, hospitalists, anesthesiologists and surgeons .

Key Features

• Definitiveaccountofperioperativecareforawiderangeofsurgicalpatients

• Asignificantreferenceworkforallhealthcareprofessionalsdealingwithsurgicalpatients

• Newminimallyinvasivesurgicalproceduresarecovered–highlightingtheirusualcourseandcommoncomplications



42 Surgery

ContentsPreface;Introduction;Part I. Medical Management:1. Anesthesia management of the surgical patient;2. Specialized nutrition support in the surgical patient;3. Preoperative testing;4. Medication safety for surgical patients;5. Informed consent and decision-making capacity;6. Ethical considerations in the surgical patient;7. Perioperative pain management;8. The medical consult;Section 1. Cardiology:9. Cardiovascular disease;10. Postoperative chest pain and shortness of breath;Section 2. Hypertension:11. Preoperative and postoperative hypertension;Section 3. Pulmonary:12. Perioperative pulmonary risk evaluation and management for non-cardiothoracic surgery;13. Perioperative management of the asthma patient;14. Acute lung injury and the acute respiratory distress syndrome;15. Postoperative pulmonary complications;Section 4. Gastroenterology:16. Peptic ulcer disease;17. Liver disease;18. Inflammatory bowel disease;19. Postoperative gastrointestinal complications;Section 5. Hematology:20. Disorders of red cells;21. Assessment of bleeding risk in patients with no history of hemostatic problems;22. Prophylaxis for deep-vein thrombosis and pulmonary embolism;23. Blood transfusion: preoperative considerations and complications;Section 6. Infectious Disease:24. Preventive antibiotics in surgery;25. HIV disease;26. Fever and infection in the postoperative setting;Section 7. Renal Disease:27. Surgery in the patient with renal disease;28. Postoperative electrolyte disturbances;Section 8. Endocrinology:29. Diabetes mellitus;30. Disorders of the thyroid;31. Disorders of the adrenal cortex;32. Disorders of calcium metabolism;33. Pheochromocytoma;Section 9. Rheumatology:34. Rheumatologic disorders;Section 10. Neurology:35. Cerebrovascular disease;

Section 13. Transplantation:42. Transplantation;Section 14. Psychiatric Disorders:43. Psychological and emotional reactions to illness and surgery;44. Depression and the surgical patient;45. Substance abuse;Section 15. Peripartum Patients:46. Care of the peripartum patient;Part II. Surgical Procedures and their Complications;Section 1. General Surgery:47. Tracheostomy;48. Thyroidectomy;49. Parathyroidectomy;50. Lumpectomy and mastectomy;51. Gastric procedures;52. Small bowel resection;53. Appendectomy;54. Colon resection;55. Abdominoperineal resection/coloanal or ileoanal anastomoses;56. Anal operations;57. Cholecystectomy;58. Common bile duct exploration;59. Major hepatic resection;60. Splenectomy;61. Pancreaticoduodenal resection;62. Adrenal surgery;63. Lysis of adhesions;64. Ventral hernia repair;65. Inguinal hernia repair;66. Laparotomy in patients with human immunodeficiency virus infection;67. Abdominal trauma;Section 2. Cardiothoracic Surgery:68. Coronary artery bypass;69. Cardiac rhythm management;70. Aortic valve surgery;71. Mitral valve surgery;72. Ventricular assist devices and cardiac transplant;73. Thoracic aortic disease;74. Pulmonary lobectomy;75. Pneumonectomy;76. Lung transplantation;77. Hiatal hernia repair;78. Esophagomyotomy;79. Esophagogastrectomy;80. Colon interposition for esophageal bypass;Section 3. Vascular Surgery:81. Carotid endarterectomy;82. Abdominal aortic aneurysm repair: open;83. Abdominal aortic aneurysm repair:

91. Facial rejuvenation;92. Liposuction;93. Facial fractures;94. Flap coverage for pressure ulcers;95. Muscle flap coverage for sternal wound infection;96. Skin grafting for burns;Section 5. Gynecologic Surgery:97. Abdominal hysterectomy;98. Vaginal hysterectomy;99. Uterine curettage;100. Radical hysterectomy;101. Vulvectomy;Section 6. Neurologic Surgery: 102. Craniotomy for brain tumor;103. Intracranial aneurysm surgery;104. Evacuation of subdural hematomas;105. Stereotactic procedures;106. Transphenoidal surgery;107. Treatment of herniated disc;Section 7. Ophthalmic Surgery: 108. General considerations in ophthalmic surgery;109. Cataract surgery;110. Corneal transplantation;111. Vitreoretinal surgery;112. Glaucoma surgery;113. Refractive surgery;114. Strabismus surgery;115. Enucleation, evisceration and exenteration;Section 8. Orthopedic Surgery: 116. Arthroscopic knee surgery;117. Total knee replacement;118. Total hip replacement;119. Fractures of the femoral shaft;120. Hip fractures;121. Lumbar spine surgery;122. Surgery for adult spinal deformity (scoliosis or kyphosis);123. Cervical spine surgery;124. Surgery of the foot and ankle;125. Lower extremity amputations;126. Surgical procedures for rheumatoid arthritis;Section 9. Otolaryngologic Surgery: 127. Otologic surgery;128. Tympanotomy tubes;129. Tonsillectomy and adenoidectomy;130. Surgery for obstructive sleep apnea;131. Endoscopic sinus surgery;132. Aesthetic facial plastic surgery;133. Surgical management of head and neck cancer;134. Reconstruction after cancer ablation;135. Surgical management of thyroid malignancies;136. Anterior cranial base surgery;137. Acute airway emergencies;Section 10. Urologic Surgery: 138. Management of


January 2013 276 x 219 mm 840pp 30 b/w illus. 978-1-107-00916-5 Hardback c. £120.00


43Surgery

Postgraduate OrthopaedicsViva Guide for the FRCS (Tr & Orth) Examination

Edited by Paul A. BanaszkiewiczDepartment of Orthopaedic Surgery, Queen Elizabeth Hospital, Gateshead

and Deiary F. KaderDepartment of Orthopaedic Surgery, Queen Elizabeth Hospital, Gateshead

DescriptionThisbookhasbeenwrittenspecificallyforcandidatessittingtheoralpartoftheFRCS(Tr& Orth) examination . It presents a selection of questions arising from common clinical scenarios along with detailed model answers . The emphasis is on current concepts, evidence-based medicine and major exam topics . Edited by the team behind the successful Candidate’sGuidetotheFRCS(Tr&Orth)Examination, the book is structured according to the four major sections of the examination; adult elective orthopaedics, trauma, children’s/hands and upper limb and applied basic science . An introductory section gives general exam guidance and end section covers common diagrams that you may be asked to draw out . Each chapter is written by a recent (successful) examination candidate and the style of each reflects the author’s experience and their opinions on the best tactics for first-time success . If you are facing the FRCS(Tr&Orth)youneedthisbook.

Key Features

• Carefullyanalysesthemarkingsystemsocandidatescanmorefullyappreciatethestandardandlevelofperformancerequiredtopass the exam

• Examiner/candidatediscussionshelpwithpreparation,highlightingthepossiblepitfallsandconsequencesofparticularanswers

• Drawsonreal-lifecandidateexperienceasalearningtoolforothers

ContentsForeword;Preface;List of abbreviations;Part I. The FRCS (Tr & Orth) Oral Examination:1. General oral guidance;Part II. Adult Elective Orthopaedics and Spine:2. Hip structured oral questions;3. Knee structured oral questions;4. Foot and ankle structured oral questions;

5. Spine structured oral questions;6. Shoulder and elbow structured oral questions;7. Orthopaedic oncology;Part III. Trauma:8. Lower limb;9. Upper limb;10. Pelvic and spinal trauma;Part IV. Children’s Orthopaedics/Hand and Upper Limb:11. Hand and upper limb;12. Children’s orthopaedics;

Part V. Applied Basic Sciences:13. Anatomy and surgical approaches;14. Pathology;15. Biomaterials and biomechanics;16. Tissues of the musculoskeletal system;17. Evidence based practice;18. Imaging and investigative techniques;Part VI. Diagrams for the FRCS (Tr & Orth): 19. Diagrams for the FRCS (Tr & Orth);Index.

Additional InformationLevel: specialist medical trainees, medical students

August 2012 246 x 189 mm 304pp 314 b/w illus. 24 colour illus. 978-1-107-62736-9 Paperback c. £45.00



44 Index

A Abdelmalak, Basem ...............................11Amor, Sandra ........................................30Analgesia, Anaesthesia and Pregnancy ....7Anesthesia for Otolaryngologic Surgery ..11Arulkumaran, Sabaratnam .....................37Atkins, Gregory .....................................30Aygun, Nafi ...........................................19

B Banaszkiewicz, Paul A. ...........................43Banerjee, Sube ......................................26Basner, Robert C. ...................................33Behavioral and Cognitive Neurology of

Stroke, The ..........................................34Behavioral Emergencies for the

Emergency Physician...........................14Berrettini, Wade ....................................24Biology of Multiple Sclerosis, The ...........30Bourgeois, James A. ...............................28Bracken, Julie ..........................................5Broome, Matthew .................................23

C Case Studies in Neurological Pain ..........29Case Studies in Polysomnography

Interpretation .....................................33Chandraharan, Edwin ............................37Chanmugam, Arjun ...............................12Chapman, Audrey ..................................21Chepenik, Lara G. ..................................14Clinical Information Systems in Critical

Care .....................................................5Cognitive Impairment in Schizophrenia ..27Comprehensive Care for Complex

Patients ..............................................28Comstock, Gary .....................................20Coward, Kevin .......................................36Culebras, Antonio ..................................35

D Digital Mammography ...........................16Dodson, Thomas ....................................42Doniger, Stephanie ................................40Doyle, John ...........................................11

E Emergency Psychiatry ............................12Erdberg, Philip .......................................28Essential Pain Pharmacology ....................4

F Fetal Therapy .........................................39Fletcher, Jean ........................................30Fox, Charles ..........................................10Frankel, Steven A. ..................................28

G Gadsden, Jeff ..........................................8Gandhi, Dheeraj ....................................19Genetic Research on Addiction ..............21Godefroy, Olivier ...................................34Gunn, Martin L. .....................................18

H Halliday, Graeme ...................................26Harland, Robert .....................................23Harvey, Philip ........................................27Haygood, Tamara Milner ........................16

J Johnson, Anthony ..................................39Jones, Matthew R. ...................................5

K Kader, Deiary F. ......................................43Kaye, Alan .............................................10Kelen, Gabor .........................................12Kilby, Mark D. ........................................39

L Lubin, Michael .......................................42

M Malhotra, Surbhi .....................................7Mallory, Mary Nan S. .............................14Maudsley Reader in Phenomenological

Psychiatry, The ....................................23Medical Management of the Surgical

Patient ...............................................42Mills, Kingston ......................................30Morrison, Cecily ......................................5

N Nurnberger, Jr, John I. ............................24

O Obstetric and Intrapartum Emergencies ..37Oepkes, Dick .........................................39Operating Room Leadership and

Management ......................................10Owen, Gareth S. ....................................23

P Pappagallo, Marco...................................4Pearls and Pitfalls in Emergency

Radiology ...........................................18Pearls and Pitfalls in Head and Neck

and Neuroimaging ..............................19Pediatric Emergency and Critical Care

Ultrasound .........................................40Postgraduate Orthopaedics ....................43Poyurovsky, Michael ..............................25Principles of Psychiatric Genetics ...........24

R Regional Anesthesia in Trauma ................8Research Ethics .....................................20

S Schizo-Obsessive Disorder .....................25Severe Domestic Squalor .......................26Shah, Gaurang ......................................19Sleep Deprivation, Stimulant

Medications, and Cognition ................31Sleep, Stroke and Cardiovascular

Disease ..............................................35Smith, Howard S. .....................................4

Snowdon, John......................................26Sommer, Claudia ...................................29Stringaris, Argyris...................................23

T Textbook of Clinical Embryology ............36Thistlethwaite, Jill E. ..............................15Triplett, Patrick ......................................12

U Urman, Richard .....................................10

V Values-Based Interprofessional

Collaborative Practice .........................15

W Wells, Dagan .........................................36Wesensten, Nancy J. ..............................31Whitman, Gary J. ...................................16Winawer, Neil ........................................42

Y Yentis, Steve ............................................7

Z Zochodne, Douglas ................................29Zun, Leslie .............................................14

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