Buerger’s Disease Prepared by: Alcantara, John Renefrank B. AdU-SN
Dec 01, 2015
Buerger’s Disease
Prepared by: Alcantara, John Renefrank B.
AdU-SN
What is Buerger’s Disease?Buerger's disease (thromboangiitis obliterans) is a
rare disease characterized by a combination of acute inflammation and thrombosis of the arteries and veins in the hands and feet. The obstruction of blood vessels in the hands and feet reduces the availability of blood to the tissues, causes pain and eventually damages or destroys the tissue. It often leads skin ulcerations and gangrene of fingers and toes. Rarely, in advanced stages of the disease, it may affect vessels in other parts of the body.
Buerger’s Disease:
AppearanceUlcers and Gangrene caused by Buerger’s Disease
Buerger’s Disease: Who It Affects?
Buerger's disease affects approximately six out of every 10,000 people. It almost always affects men, ages 20 to 40, who smoke or chew tobacco. Recently, however, more women and men over the age of 50 have been diagnosed with Buerger's disease. This disorder is still very uncommon in children, but it may occur in those with autoimmune diseases. Buerger's disease is most common in the Orient, Southeast Asia, India and the Middle East, but is rare among African-Americans.
Buerger’s Disease: Symptoms:
Enlarged, red, tender cord-like veins Pain or tenderness Numbness and tingling in the limbs Skin ulcers or gangrene of the digits
Discoloration Two or more limbs affected Pain may increase with activity such as walking and decrease with
rest Pulse may be decreased or absent in the affected extremity Symptoms may worsen with exposure to cold or with emotional
stress
Clinical Manifestations: Pain and weakness in your legs and feet or your arms and hands
Swelling in your feet and hands Fingers and toes that turn pale when exposed to cold (Raynaud’s
phenomenon) Open sores on your fingers and toes Pathognomonic sign: intermittent claudication (pain induced by
insufficient blood flow during exercise) in the feet and/or hands, or pain in these areas at rest.
Leg/foot numbness Leg/foot tingling Leg/foot burning Leg/foot paresthesia Leg/foot pain worse with exertion Insomnia Cold hyper sensibility Sudden sweating Weak/absent pulse posterior tibial and dorsalis pedis
Signs and symptoms:Pain- it is the most outstanding symptom - due to intermittent claudication.
Rest pain with persistent ischemia of 1 or more digits – due to occlusion of decreases blood flow. Paresthesia – due to diminished nerve sensation. Fingers and toes turn pale when exposed to cold (Raynaud’s phenomenon) – due to decreased blood flow as affected by cold temperature. Absent or weak tibial pulse Cyanosis - ( cyanosis bluish discoloration of the skin and mucous membrane due to lack of oxygen in the blood) a later manifestation. Ulcerations and gangrene – if there is prolonged insufficient blood supply.
PATHOPHYSIOLOGY
Precipitating Factor;
Gender: Male
Age: 20-60 y/o
History (HPN, Hyperlipidemia
GeneticsRace:
Southeast Asian
Predisposing Factors;
Lifestyle (Cigarette smoking, chewing of tobacco, sedentary lifestyle)
Environment: exposure to cold, stressful environment
Plaques/Deposits of Nicotine on the veins
Inflammation of the small and medium-sized arteries
and veins of the extremities
Thickened artery and
veins Platelets deposits on the thickened artery
Ffibrinoid occlusionImpaired
blood supply IschemiaInjury to
blood vesselsNecrosis
Early Signs and Symptoms
Claudication type of pain
Color Changes (Pallor)
Temperature changes Cold Sensitivity
(Reynaud’s phenomena)
Ulceration Gangrene
Advance/late Signs and Symptoms
Thrombophlebitis with
trauma Ulceration Gangrene Pulsation of the posterior
tibial and dorsalis pedis arteries are weak or absent.
Color Changes (Cyanotic)
How is Buerger’s disease
diagnosed?
Buerger’s disease can be mimicked by a wide variety of other diseases that cause diminished blood flow to the extremities. These other disorders must be ruled out with an aggressive evaluation, because their treatments differ substantially from that of Buerger’s Disease (for Buerger’s, there is only one treatment known to be effective: complete smoking cessation).
Diseases with which Buerger’s Disease may be confused include atherosclerosis (build–up of cholesterol plaques in the arteries), endocarditis (an infection of the lining of the heart), other types of vasculitis, severe Raynaud’s phenomenon associated with connective tissue disorders (e.g., lupus or scleroderma), clotting disorders of the blood, and others.
Angiograms of the upper and lower extremities can be helpful in making the diagnosis of Buerger’s disease. In the proper clinical setting, certain angiographic findings are diagnostic of Buerger’s. These findings include a “corkscrew” appearance of arteries that result from vascular damage, particularly the arteries in the region of the wrists and ankles. Angiograms may also show occlusions (blockages) or stenoses (narrowings) in multiple areas of both the arms and legs.
Pictured below on the left is a normal angiogram. On the right, is an abnormal angiogram of an arm demonstrating the classic “corkscrew” appearance of arteries to the hand. The changes are particularly apparent in the blood vessels in the lower right hand portion of the picture (the ulnar artery distribution).
Treatment and Course
of Buerger’s Disease
It is essential that patients with Buerger’s disease stop smoking immediately and completely. This is the only treatment known to be effective in Buerger’s disease. Patients who continue to smoke are generally the ones who require amputation of fingers and toes.
Despite the clear presence of inflammation in this disorder, anti-inflammatory agents such as steroids have not been shown to be beneficial. Similarly, strategies of anticoagulation (thinning of the blood with aspirin or other agents to prevent clots) have not proven effective. The only way to prevent the progression of the disease is to abstain from all tobacco products.
Diagnostics: Arteriography - may indicate a proximal
source of emboli. It is the most conclusive diagnostic procedure for peripheral vascular diseases.
Ultrasound - may indicate presence of distal extremity ischemia (indicated by claudication, pain at rest, ischemic ulcers or gangrene).
Medical Management Analgesics are used for pain relief associated with
Buerger’s disease and vasodilators to increase tissue perfusion.
If wound care is required, topical antibiotics are applied with dressing changes.
Enzymatic debridement agents may be used as a replacement to surgical debridement.
Sympathectomy which involves the interruption of selected section of the sympathetic nervous pathways is used to treat vasospasms.
Ulcerations may require debridement and possible skin grafting.
In extreme cases, disease progression of Buerger’s disease there is circulation impairment, and amputation of digits or extremity may be needed.
Nursing Diagnosis Ineffective peripheral tissue perfusion related to impaired
circulation.Pain related to diminished oxygen flow to the affected extremity.Fear and anxiety related to actual or potential serious
complications.
Nursing Management
Patient teaching, instruct the patient to do the following several times a day:
Lie flat on a bed with both legs elevated above the level of the heart for two to three minutes.
Next sit on the edge of the bed with the legs dependent for three minutes
Then exercise the feet and toes by moving them up, down, inward, then outward.
Lastly, return to the first position and hold for five minutes.
Provide for ulcer debridement and healing
Remove dead or damaged material from the wound, using wet-to-dry dressing with saline solution and coarse-mesh gauze filled with cotton.
Use whirlpool therapy to debride the ulcer bed.
Consider using an enzymatic debrider to aid removal of debris.
Provide additional intervention to promote venous return and healing, maximize comfort and provide client education for measures to prevent venous stasis ulcer.
Administer medications which may include antibiotics.
The patient is encouraged to make the lifestyle changes necessitated by the onset of a chronic disease, including pain management and modifications in diet, activity, and hygiene (skin care).
The nurse assists the patient in developing and implementing a plan to stop using tobacco- to prevent further occlusion of the blood vessels
Assessing for pain – to monitor if it being tolerated or needs medication to relieve pain.
obtaining blood pressure – serves as a baseline data for peripheral pulse
assessing for signs of ulcer formation assessing for signs of gangrene Foot care – to decrease the occurrence of infection
and gangrene. protect from trauma to avoid source of infection enough rest
Thank You!!!