BSG Pathology Section Liver Slide Seminar, Birmingham, March 12 2008 Clinical Summaries - Stefan Hübscher Prof. Stefan Hubscher Case 1 Male, age 52. Recent onset of jaundice and abnormal LFTs. AST 793 (normal 5-43), ALP 655 (70-330), bilirubin 172 (1 22). ANA positive (1:100), SMA positive, IgG 19.5 (normal 6- 16). Liver biopsy.
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BSG Pathology Section Liver Slide Seminar, Birmingham, March 12 2008 Clinical Summaries - Stefan Hübscher Prof. Stefan Hubscher Case 1 Male, age 52. Recent.
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BSG Pathology Section Liver Slide Seminar, Birmingham, March 12 2008Clinical Summaries - Stefan Hübscher
Prof. Stefan Hubscher Case 1Male, age 52.Recent onset of jaundice and abnormal LFTs.AST 793 (normal 5-43), ALP 655 (70-330), bilirubin 172 (1-22).ANA positive (1:100), SMA positive, IgG 19.5 (normal 6-16).Liver biopsy.
• Case 2
• Female, age 54
• Potential donor liver retrieved from another centre in the UK
• Died from subarachnoid haemorrhage. No history of alcohol.
• Liver not used because of macroscopic appearance - generally fatty, atrophy of segment 5 in right lobe
• Wedge biopsies taken from left lobe, segment 5 and segment 6. Slide submitted is from left lobe biopsy.
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• Dr Judy Wyatt
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• Case 3
• Female, age 3
• Developed ALL age 2½.
• Presented with acute veno-occlusive disease during 6TG treatment which settled with supportive treatment. Changed to 6MP.
• 1 year later, presented with haematemesis, due to bleeding oesophageal varicies.
• One year after that developed respiratory failure, requiring continuous oxygen.