BROOKLYN 3 STUDENTS Adam ROSCOE Samuel THOMAS Fri 30 th Aug 2013 Session 2 / Talk 5 11:25 – 11:35 ABSTRACT A short presentation on Gouty arthritis, to help further our understanding of a common indication seen on Xray requests. In our presentation we are going to cover the basics of Gout, including a definition, pathological classification, history and nature of this joint pathology, and also clinical management of patients suffering from Gout. Gout is a type of arthritis that results from an inflammatory response to a build up of uric acid in the vascular system progressing to erosion of the articulating surfaces of bones. It is an inherited metabolic disease and is classed either as an acute or chronic condition. Gout is more prevalent in males and can be influenced by diet and lifestyle. The pathogenesis of Gout involves the metabolism of Purines, a type of nucleic acid found in beer, fish, and mushrooms. This results in a waste product called Uric acid, which if not regulated by the Kidney, will crystallize and lead to bone erosion. Clinicians suspecting Gouty arthritis in their patient are likely to consider the patient’s history, and send for tests such as Xray or synovial joint aspirations.
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BROOKLYN 3
STUDENTS
Adam ROSCOE Samuel THOMAS
Fri 30th Aug 2013
Session 2 / Talk 5
11:25 – 11:35
ABSTRACTA short presentation on Gouty arthritis, to help further our understanding of a common indication seen on Xray requests. In our presentation we are going to cover the basics of Gout, including a definition, pathological classification, history and nature of this joint pathology, and also clinical management of patients suffering from Gout.Gout is a type of arthritis that results from an inflammatory response to a build up of uric acid in the vascular system progressing to erosion of the articulating surfaces of bones. It is an inherited metabolic disease and is classed either as an acute or chronic condition. Gout is more prevalent in males and can be influenced by diet and lifestyle. The pathogenesis of Gout involves the metabolism of Purines, a type of nucleic acid found in beer, fish, and mushrooms. This results in a waste product called Uric acid, which if not regulated by the Kidney, will crystallize and lead to bone erosion. Clinicians suspecting Gouty arthritis in their patient are likely to consider the patient’s history, and send for tests such as Xray or synovial joint aspirations.
Gouty ArthritisAdam RoscoeSam Thomas
Year 3 Medical Imaging Unitec
OverviewDefinition of Gout
Pathological classification
History of Gout
Gout Aetiology & Pathogenesis
Clinical management of Gout patients
DefinitionGout is a type of arthritis
Gout results from an inflammatory response to build up of Uric acid in blood
Progresses to Urate crystals in joints
Urate crystals erode articulating surfaces of bone
Clinical tests: Blood/UrinePerformed to assess uric acid levels
when Gout diagnosis is unclear
Clinical tests: XrayPerformed mainly in later stages of
Gout
Case studyPatient had pain, swelling, deformities
of 1st MTP joints.
Swelling around 3rd MCP joint in both hands
Case study
ConclusionMRT contact with Gout patients is
usually in later stages of disease
Be mindful positioning as the patient may be in pain
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Zare, F., Magnusson, M., Bregstrom, T., Brisslert, M., Josefsson, E., Karlsson, A., Tarkowski, A. (2006). Uric Acid, a nucleic acid degredation product, down-regulates dsRNA-triggered arthritis. Journal of Leukocyte Biology, 79(3), 482-4. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16387838