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Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center for Neuroprosthetics, EPFL The BioRobotics Institute, Scuola Superiore Sant’Anna DISCLOSURE: Dr. Micera holds shares of Sensars Neuroprosthetics, a newco working to commercialize “bionic” limbs
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Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

May 26, 2020

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Page 1: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

Bridging the Innovation Gap:the “Bionic Hand” and FET

Silvestro MiceraBertarelli Foundation Chair in Translational NeuroEngineering, Center for Neuroprosthetics, EPFL

The BioRobotics Institute, Scuola Superiore Sant’Anna

DISCLOSURE: Dr. Micera holds shares of Sensars Neuroprosthetics, a newcoworking to commercialize “bionic” limbs

Page 2: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

2Translational Neural Engineering Bringing neurotechnology to clinical trials

OUR DREAM…

1. PHASE 1: Which kind of connection with the nervous system?2. PHASE 2: Which kind of hand prosthesis?3. PHASE 3: How much the patient is going to exploit this new

communication channel?4. PHASE 4: Is market exploitation possible?

Page 3: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

3Translational Neural Engineering Bringing neurotechnology to clinical trials

INTER EU

project

1994-1997

GRIP EU project

1997- 2000

Micera et al., IEEE T-NSRE, 2008

PHASE 1 - The building blocks…

Identification of the “optimal” neural interface

Page 4: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

4Translational Neural Engineering Bringing neurotechnology to clinical trials

INTER EU

project

1994-1997

GRIP EU project

1997- 2000

CYBERHANDNeuroboticsEU projects

2002- 2006

Sensorized hand prostheses

First implant in a patient

Intraneural electrodes (LIFE)

PHASE 2 – System integration…

1. Biomechatronic Hand

Analysis of the ENG signals recorded

2. Embedded Biomimetic sensors:

- within the structure

- within the glove

Different electrodes

6. Receiver

7. Transmitter

Stump

8. Decoding patient’s intentions and

Embedded closed-loop control of the artificial

hand

Page 5: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

5Translational Neural Engineering Bringing neurotechnology to clinical trials

NEBIAS EU project

2014- 2018

First patient with bidirectional control

PHASE 3 - The clinical challenge…

INTER EU

project

1994-1997

GRIP EU project

1997- 2000

CYBERHANDNeuroboticsEU projects

2002- 2006

First implant in a patient

Intraneural electrodes (LIFE)

Sensorized hand prostheses

Page 6: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

6Translational Neural Engineering Bringing neurotechnology to clinical trials

PHASE 4 - Towards market exploitation…

Clinical results(NEBIAS)

FET Launchpad

project

Which kind of market?

EIC Fast Track to Innovation

Page 7: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

Lessons learnt and some proposals

• Finding a path is NOT a linear process. It is often a MAZE. The EIC Pathfinder should take into consideration to allow innovative projects to go the next funding schemes

– Objectives of the projects could be updated (GRIP yellow flag…)

– Maybe partners could be changed during the project

– Failures should be “encouraged”

• The FET Progamme has been very flexible in the past thanks to the excellent attitude of the Officers but this flexibility should become “easier” to implement

Page 8: Bridging the Innovation Gap€¦ · Bridging the Innovation Gap: the “Bionic Hand” and FET Silvestro Micera Bertarelli Foundation Chair in Translational NeuroEngineering, Center

Lessons learnt and some proposals

• Finding the reviewers with the “right” attitude to increase the probability of success. Better to chose scientists already involved in previous similar projects

• EIC has to be a flexible “multi-port” “open” framework. Innovation means different things and all of them need to find opportunity under the EIC umbrella

• Coaching should be strongly encouraged as soon as possible during the project. It is not