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0 Mismatched Disease : "Do You Want to Treat the Lesion or the Patient?" Bong Bong - - Ki Lee, MD, PhD Ki Lee, MD, PhD Division of Cardiology Division of Cardiology Kangwon National University Hospital Kangwon National University Hospital Chunchon, Korea Chunchon, Korea
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Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

Oct 08, 2020

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Page 1: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Mismatched Disease: "Do You Want to Treat the Lesion or the Patient?"

BongBong--Ki Lee, MD, PhDKi Lee, MD, PhD

Division of CardiologyDivision of CardiologyKangwon National University Hospital Kangwon National University Hospital

Chunchon, KoreaChunchon, Korea

Page 2: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Case #1

• 78/F

• CC: effort angina x 1 month (1 yr ago)

• Risk factors: old age

• Treadmill test

- not performed for s/p THR (Lt hip)

Page 3: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Coronary angiogram11 Nov, 2009

Page 4: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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PCI11 Nov, 2009

Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm)

Pre-dilatation Stenting

Page 5: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Final CAGSuccessful result

Page 6: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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8 months later…

• She complained recurred chest pain, but the pain character was atypical.

• We performed follow up CAG.

Page 7: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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F/U Coronary angiogram27 Aug, 2010

Page 8: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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We measured FFR

Then, deferred PCI…

Page 9: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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EndoscopyErosive gastritis & duodenal ulcers

Page 10: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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GI medication started

• Then the ‘chest pain’ had been improved.

Page 11: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Case #2

• 58/F

• CC: effort angina x 3 weeks

• Risk factors: Hypertension, T2DM

• Treadmill test

- Positive at stage 3

Page 12: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Treadmill test

Baseline

Angina at stage 3

Page 13: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Coronary angiogramRCA

Page 14: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Coronary angiogramLeft coronary system

Page 15: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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IVUS & FFR for RCA lesion

Deferred!

Page 16: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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IVUS & FFR for LAD lesion

Page 17: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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PCI for LAD Lesion

Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm)

Pre-dilatation Stenting

Page 18: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Final CAGSuccessful result

Page 19: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Treadmill test follow up

Baseline

Stage 4

Page 20: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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If I Did “Unnecessary PCI”……

• Might experienced PCI related complications- Restenosis

- Stent thrombosis

- No-reflow

- Coronary perforation

- Access site complication

• Anti-platelet therapy must be reinforced

• The patient must paid more money…

Page 21: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Summary & ConclusionSummary & Conclusion

• FFR can be useful as an alternative to stress test in the cath lab to have decision making-treat or not treat.

• “Start the procedure with FFR, finish the procedure with IVUS” rule seems quite feasible.

• FFR is a useful tool to avoid “unnecessary PCI”.

Page 22: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Page 23: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Page 24: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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Page 25: Bong-Ki Lee, MD, PhD · 3 PCI 11 Nov, 2009 Sapphire 3.0 x 15 mm (6 atm) PICO-Elite 3.0 x 18 mm (12 atm) Pre-dilatation Stenting

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