Blood Typing

Blood Typing

Catalyst: In camels, having a large hump is

dominant over having a small hump. Create a Punnett square to show the

potential offspring of a heterozygous camel and a camel with a small hump.

Make sure to list the genotype and phenotype percentages!

Write in complete sentences!

Don’t talk during the Catalyst!

Have you ever wondered…

Why we have different types of blood?

Why could you die if you get a transfusion of the wrong type of blood?

Objectives

By the end of today, SWBAT…Identify blood type genotypes and phenotypes

Determine the correct type of blood to transfuse into a patient

Agenda

Catalyst/HW ReviewQuizTypes of bloodAre you a positive person?Whiteboards practiceVIDEO GAME PRACTICEExit Question

Catalyst/Homework Review

Blood Typing

Sometimes there are more than two alleles for a trait. The most important case for you to learn about is… blood type!

Key Point #1: Blood type has three alleles: IA, IB, and i. IA and IB are both dominant (co-dominant).

i is recessive.

Types of blood

IA and IB are co-dominant IA IA = Type A IB IB = Type B IA IB = Type AB

i is recessive IA i = Type A IB i = Type B i i = Type O

Since IA and IB are both

dominant, they are

expressed at the SAME

TIME

Since IA and IB are both

dominant, they are

expressed at the SAME

TIME

Antigens and Antibodies

Key Point #2: Antigens determine blood type. Antibodies attack antigens. If you receive the wrong type of blood, your

antibodies will attack the new antigens, causing blood cells to clump and crack.

Type A blood has A antigens, and B antibodies.

Type B blood has B antigens, and A antibodies.

Type AB blood has A and B antigens, and no antibodies

Type O blood has no antigens, and A and B antibodies

Positive or Negative

Key Point #3: Rhesus factor determines if your blood type is positive or negative If you have Rh factor, your blood is

positive If you lack the Rh factor, your blood is

negative

Whiteboards

For each problem… Determine the blood type Determine if the person can receive the transfusion

If the person CANNOT receive the transfusion, explain what will happen if the wrong type blood is given to them

It’s time to pretend that we’re…

Guided Practice

Bob Dylan’s blood is IAIA, and lacks Rh factor. What type blood does he have? Can he receive Type B blood? Can he receive Type O blood?

Guided Practice

D’Angelo’s blood is IBi, and has Rh factor. What type blood does he have? Can he receive Type AB blood? Can he receive Type B blood?

Guided Practice

Goapele’s blood is IAIB, and lacks Rh factor. What type blood does she have? Can she receive Type B Rh- blood? Can she receive Type A Rh+ blood?

Guided Practice

Dave Grohl’s blood is ii, and has Rh factor. What type blood does he have? Can he receive Type O Rh+ blood? Can he receive Type AB Rh- blood?

Guided Practice

Kid Cudi’s blood is IAIA, and lacks Rh factor. What type blood does he have? Can he receive Type O Rh- blood? Can he receive Type AB Rh+ blood?

Guided Practice

Nujabes’s blood is IBi, and has Rh factor. What type blood does he have? Can he receive Type B Rh- blood? Can he receive Type A Rh+ blood?

Guided Practice

Drake’s blood is IAIB, and lacks Rh factor. What type blood does he have? Can he receive Type A Rh- blood? Can he receive Type B Rh+ blood?

Guided Practice

Lady Gaga’s blood is ii, and has Rh factor. What type blood does she have? Can she receive Type AB Rh+

blood? Can she receive Type O Rh- blood?

SICK VIDEO GAME

http://nobelprize.org/educational_games/medicine/landsteiner/landsteiner.html

Exit Question

Lil’ Wayne’s blood is IAi, and has Rh factor. What type blood does he have? Can he receive Type A Rh- blood? What will happen if he donates

blood to someone who is Type AB Rh-?

Write in complete sentences!

Don’t talk during the Exit Question!