Keith Johnston Research Group Nanotechnology/Colloid Science [email protected]CPE 5.414 512-471-4617 Biomedical and Pharmaceutical Nanotechnology: Imaging and Therapeutics – Magnetic/optical/therapeutic nanoparticles -cancer and atherosclerosis – Protein drug delivery (oral, depot, pulmonary, parenteral) Nanotechnology for Energy: Fundamentals and Applications – Nanocrystal/Mesoporous composites • Supercapacitors and batteries • Catalysis- fuel cells, water oxidation – Nanotechnology for Enhanced Oil Recovery and CO 2 Sequestration • Electromagnetic imaging • Emulsions/foams for mobility control
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Biomedical and Pharmaceutical Nanotechnology: Imaging and Therapeutics
Keith Johnston Research Group Nanotechnology/Colloid Science [email protected] CPE 5.414 512-471-4617. Biomedical and Pharmaceutical Nanotechnology: Imaging and Therapeutics Magnetic/optical/therapeutic nanoparticles -cancer and atherosclerosis - PowerPoint PPT Presentation
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Keith Johnston Research GroupNanotechnology/Colloid Science
Biomedical and Pharmaceutical Nanotechnology: Imaging and Therapeutics– Magnetic/optical/therapeutic nanoparticles -cancer and atherosclerosis– Protein drug delivery (oral, depot, pulmonary, parenteral)
Nanotechnology for Energy: Fundamentals and Applications
– Nanocrystal/Mesoporous composites• Supercapacitors and batteries• Catalysis- fuel cells, water oxidation
– Nanotechnology for Enhanced Oil Recovery and CO2 Sequestration• Electromagnetic imaging• Emulsions/foams for mobility control
Novel concept: build nanoclusters from nanoparticles
30 nm end-to-end
Antibodies,siRNA
Small size (20 to 50 nm): challenging to synthesize* permeation of cell membranes, leaky vasculature in cancers* prolonged circulation in bloodstream* modulate biological pathways including apoptosis
Nanoclusters of nanoparticles* pack intense and variable functionality (like viral capscids)* optical(gold), and magnetic(iron oxide) : imaging* targeting agents (Abs, siRNA)* drugs for delivery