biology

BIOL 102

21 January 2015

I have performed biological research since I was an undergraduate

B.A. Biochemistry, University of Oregon

Studying how proteins read DNA and cause RNA to be produced

and research technician

Studying olfactory receptor (OR) genes in mice

and research technician

Young et al. (2002) Human Molecular Gene0cs

Restrooms at Pike Place Market

My graduate career: studying sex chromosomes in SeaOle (Ph.D. in Molecular and Cell Biology)

Sex chromosomes are often heteromorphic; autosomes are not

Human male karyogram

Y Chromosome DegeneraTon

Human X and Y chromosomes

The demise of sex chromosomes?

Might a sex chromosome completely erode? What happens then?

STckleback Fish Sex Chromosome GeneTc Diversity

Ross and Peichel (2008) Gene0cs; Ross, et al. (2009) PLoS Gene0cs

Y chromosomes do not always shrink!

Caenorhabdi0s briggsae

Self-ferTle hermaphrodites and males Small (~ 1 mm) Large brood sizes (150 +) Short generaTon Tme (3 days)

not shown actual size

My post-doctoral career: sh to shbait University of Maryland, College Park

Why study C. briggsae? Diversity

AF16 average self-brood size: 220 HK104 average self-brood size: 190 AF16-HK104 hybrid average self-brood size: 175

Why are sick hybrids interesTng?

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Darwins birthplace, Shrewsbury UK

At Fresno:

Agenda

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