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Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1
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Page 1: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Bio-Intro

Lisbeth N. FinkAdjunkt, Nutritional Immunology Group

CBS, DTU

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Page 2: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

DNA

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Page 3: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Eukaryot >< Prokaryot celle

Ingen introns

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Page 4: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

DNA sequences = summary of information

5’ AGCC 3’3’ TCGG 5’

5’ ATGGCCAGGTAA 3’DNA backbone: http://en.wikipedia.org/wiki/DNA(Deoxy)ribose: http://en.wikipedia.org/

Ribose

1

23

4

5

Deoxyribose

1

23

4

5

5’

3’

5’

3’4

Page 5: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Transkription - afskrivning

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Page 6: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

mRNA-processering

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Page 7: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Transkription og translation

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Page 8: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Translation - oversættelse

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Page 9: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Protein-ladninger

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Page 10: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Mutationer

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Page 11: Bio-Intro Lisbeth N. Fink Adjunkt, Nutritional Immunology Group CBS, DTU 1.

Signalering

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IL-10-signalering

• Cytokiner er proteiner der produceres af (bl.a.) immunceller og virker på (bl.a.) immunceller (leukocytter/hvide blodlegemer)

• IL-10 er et cytokin, der nedregulerer immunrespons, startet af f.eks. en bakterie

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