Beef diseases directory
Beef diseases directory
1
The technical information in this booklet was supplied by NADIS, Jonathan Statham, Bishopton Vets/RAFT solutions Ltd (a member of XL Vets) and compiled by Katie Brian, AHDB Beef & Lamb.
AHDB Beef & Lamb Better Returns Programme is grateful to all those who have commented and contributed to this publication.
Photography: Jonathan Statham, MSD Animal Health, NADIS, and Zoetis.
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Contents The costs of diseaseDiseasesintheUKcattleindustryaccountforhugelossesandareamajorwelfareconcern.Ateamapproachtofarmhealthplanning,involvingthefarm’svet,performancerecordingandidentifyingareasforimprovement,canincreasereturnsforbeefproducers.
Diseasescauseproductionlossesthroughforexample,reduceddailyliveweightgain(DLWG),orincreasedcostssuchasfeed–eventhoughanimalsmaynotappeartobeill.Withoutattentiontoherdperformance‘sub-clinical’lossescansoonaddup.
Inthispublication,wehighlightever-presentandsignificantconditionsaffectingthebeefindustry.Weprovideinsightintothemainsymptomsandriskfactors–alongsidethemosteffectivepreventionandtreatmentprotocols.However,werecommendproducersshouldalwaysconsulttheirvetforclinicaldiagnosisandtodiscusseffectivetreatments.
Discussingafarmhealthplanwiththevetprovidestheidealopportunitytosetoutastrategicapproachtodiseasepreventionandmanagementintheherd.
KatieBrianBRPProjectManager
1
2 Abortion
4 Bovine Viral Diarrhoea
6 Diarrhoea
8 Eye conditions
10 Hypomagnesaemia
12 Johne’s disease
14 Lameness
16 Liver fluke
18 Lungworm
20 Midge-borne diseases
22 Parasitic gastroenteritis
24 Plant poisoning
26 Respiratory disease
28 Septicaemia
30 Skin conditions
32 Summer mastitis
34 Best practice
Officiallyrecordedcasesofabortionincattlearerelativelylowbutthisisalmostcertainlyduetounder-reportingbyfarmers.Abortioncoversallformsofinfertilityfromtheloss(re-absorption)ofaveryyoungfoetustoprematurebirth,butisusuallydefinedastheproductionofoneormorecalvesbetween50and270daysofgestation.
Abortionisusuallycausedbyoneofanumberofinfectiousagentsandmayaffectoneortwoindividualanimals,butitcanoftencausewidespreadproblemsinaherd.Diagnosisofbovineabortioncanbechallenging.Failuretoidentifythecauseofanabortionquicklyandtakeactioncanresultinaproblemleadingtosignificantfinancialloss.
Costs and implications
Evenasinglecaseofabortionrepresentsasubstantiallossinabeefsucklerherd,astheaffectedcowiseffectivelyrenderedunproductivefortheyear.Purchasingareplacementcalftofosterontoacowthathasabortedpresentsnewriskstotheherd.
Abortionsmayoftenbeanindicationoffarwiderdiseaseproblemsandasinglecasecanquicklybecomemoresignificant.
Manycausesofabortionarezoonoticdiseaseswhichmeanstheycanbetransmittedtohumans.Youngchildren,pregnantwomenandtheelderlyareespeciallyvulnerable.
IntheUK,allabortionsandprematurebirths(beforeday271ofgestation)mustbereportedtoDefrawhowillthendeterminethenecessarycourseofaction.
Common causes and consequences
Viral:• InfectiousBovineRhinotracheitis(IBR,page26)
• BovineVirusDiarrhoea/MucosalDisease(BVD/MD, page4)Bacterial:
• Leptospirosis Abortionoftenoccurssixtotwelveweeksafter infection,usuallyinlatepregnancy.Alsoassociated withreducedfertilityandthebirthofweakcalves.
• Campylobacter foetus venerealis Abortionandretentionofdiseasedfoetalmembranes atfourtosevenmonthsofpregnancy,typicallyfirst recognisedbyreturnstooestrusfollowingservicebya carrierbull.CattlebredbyAIarenotaffected.
• Brucella abortus ThelastoutbreakinGreatBritainwasin2004,despite beingofficiallyeradicatedin1983.Veryhighlevelsof abortionoccurinnewlyinfectedherds.
• Salmonella Abortiontypicallyoccursinlatepregnancy.Byfarthe commonestcauseisS.dublininfection(whenabortion
oftenoccursinlatesummer),followedbyS.typhimurium.Ingestiontoabortiontypicallytakessixtoeightweeks.
• Listeria monocytogenes Sporadicabortionduringthewintermonths,linkedto verypoorqualitysilage.
• Bacillus licheniformis Sporadicabortionusuallyinlatepregnancy,most
commonlyoccurringinnorthwestEnglandandScotlandandduetothepresenceofBacillusbacteriainmouldyhay,straw,silageandotherfeedstuffs.
Protozoal:
• Neospora caninum Themostcommonlydiagnosedcauseofbovineabortion
(12.5%ofinvestigatedcases),mostcommonatfivetosixmonthsofpregnancy.Infectioniscarriedbydogsandhoundpacksandispassedonintheirfaeces.
Abortion
2 3
Fungal:
• Mycotic (fungal) abortion Sporadicabortiontypicallyinthewintermonthsand
mostcommonlyinthewestcountryfollowingharvestingconditionsthatpromotefungalgrowthonhay,silageorstraw.Typicallyaffectscowsinmid-latepregnancy,eveniftheinfectionispickedupearlier.Mayaffectupto10%oftheherdinsomecircumstances.
Early identification
Lossofthefoetusbeforethreemonthsmaynotbedetecteduntilthecowunexpectedlyreturnstooestrus.
Ifabortionoccurslaterthanthreemonthsthefoetusmaybefound,especiallywhencattlearehoused,butretainedfoetalmembranesmaybetheonlyevidence,particularlyifwildanimalshavedisposedofthefoetus.
Prevention and control
• Biosecurity and disease-free status Strictbiosecuritytomaintaindisease-freestatusisthe
firstpriorityinminimisingtheriskofabortion.
Abortionsmustbereportedanditisimportantto isolateabortedcowsanddisposeoftheproductsof abortionwhereverpossibletoavoidpotentialvector
animalsgainingaccess;itmaybeadvisabletokeepsamplesforanalysis.
InthecaseofBrucella,UKcontrolmeasuresinclude thetestingofallbreedingstockover24months.
• Vaccination Vaccinationshouldbeusedtomaintaintheherd’s
disease-freestatuswhereappropriate.IBR,BVD/MDandS.dublincanallbecontrolledthroughvaccination.
• Feed quality Severaloftheorganismscausingabortionoriginatein poorqualityfeed(egListeria,Bacillusandahostof
fungalorganismsandmycotoxins).Itisthereforeessentialtoapplythehigheststandardsatalltimestoharvestingandfeedstorageprocedures.Ifcontaminationhasoccurred–bevigilantandremovepotentiallyharmfulfeeds.
Anabortedfoetusatthreetofourmonths.
Retainedfoetalmembranesmaybetheonlyevidenceofabortion.
Mouldysilagemaybeaprecursortoabortion,butriskassessmentisdifficult.
Thisin-calfcowdrinkingsurfacewaterclosetoadungmiddencouldbeatriskofpickingupaninfectionthatcouldcauseabortion.
AbortionA
bortion
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BovineViralDiarrhoeaisawidespreadinfectiousdiseaseofcattlethatisusuallytransmittedthoughdirectcattle-to-cattlecontact.ItiscausedbyavirusandlingersinherdsthroughPersistentlyInfected(PI)animals(whichcanappearclinicallynormal).Itcanalsodevelopintoanacuteformasatemporaryinfection,orfollowingchangesintheviruswithinPIanimals,asthefatalconditionmucosaldisease(MD).
NaturalvaccinationwithexposuretoPIanimalsisunreliableandriskscreatingfreshPIswithexposuretopregnantfemales.Goodvaccinesareavailableandshouldbeused.
BVDTypeIIisanemergingriskfortheUK.Althoughnotcurrentlyconfirmedaspresent,ithasbeenresponsibleforsevereoutbreaksofdiseaseinEurope,particularlytheNetherlands,Germanyandneighbouringstates.
Itismoresevereintheacuteformandcancausedeathinadultcattle.VaccineswithBVDTypeIIprotectionareemergingontotheUKmarketandcontrolshouldbediscussedwiththevet.
Costs and implications
BVDcanleadtosignificantlossesresultingfromreducedfertility,poorproductionandincreasedsusceptibilitytootherinfections,especiallyinyoungcalves.Lossesareparticularlyseverewherethevirusisintroducedtogroupsofsusceptiblebreedingcattle.
Mucosaldiseasetypicallycausesthedeathoftheanimalwithinfivetotendays,socasesshouldbeculledondiagnosis.Calvesbornwitheyeandbraindefectsduetovirusinfectionduringdevelopmentshouldalsobeculled.
Risk factors and susceptibility
AllcattlearepotentiallysusceptibletoinfectionwiththeBVDvirus.Theviruscanbespreadinthesemenofpersistentlyinfectedbulls(orbullswithatemporaryinfection).
High risk situations:
• Introductionofpersistentlyinfectedcattleintoa naïveandunprotectedherd
• Introductionofnaïve(uninfectedcattle)intoan infectedherd
Early identification
• Non-pregnantcattleexposuretotheBVDvirus causesatemporaryinfectionbeforeprotective
antibodiesareproducedwithinthreetofourweeks.Thisinfectionmaytemporarilylowerimmunitytootherinfectiousdiseases,suchassalmonella,respiratoryinfectionsandcoccidiosis,leadingtomoreseveresymptomsorillthriftparticularlyinyoungcalves
• ForcattleinearlypregnancyexposuretotheBVD virusduringthefirst110dayscancausethe
followingproblems:
• Lowpregnancyrates
• Embryodeathandreturntoheat
• Foetaldeath/abortion
• Mummifiedfoetuses
• Birthdefectsofnervoussystemandeyes
• Weak/prematurecalves
• Livepersistentlyinfectedcalves
• MucosaldiseaseoccurswhentheBVDvirusin persistentlyinfectedanimalschangestoacytopathic
(cellkilling)virus,typicallyin6-12montholdcalves,causingthesesymptoms:
• Depression,salivationandfever
• Anorexia
• Mouthandmuzzleulcers
• Pusdischargesfromeyesandnostrils
• Severediarrhoeawithbloodandshredsof gutlining
Bovine Viral Diarrhoea(BVD)
4 5
Prevention and control
• ‘Naturalvaccination’–whereinfectionispresentand persistentlyinfectedcalvesactas‘naturalvaccinators’ andadultcattleareimmune,meansthediseasecanbe presentinaherdwithminimalclinicaldisease symptomsorobviouslosses.Introductionofnaïve breedingfemalestosuchaherdwill,however,resultin significantlosses
• Vaccination–whereallbreedingfemalesarevaccinated, thediseaseiscontrolledbypreventingBVDinfectionof
developingfoetusesduringpregnancyandstoppingtheproductionofpersistentlyinfectedcalves.BVDvaccinestypicallyinvolvetwodoses,threetofourweeksapartbeforefirstservicefollowedbyannualboostervaccinations
• Eradication–wholeherdbloodtestingandelimination ofallpersistentlyinfectedcarrieranimalscaneffectively
eradicateBVDfromtheherd.Thismustbebackedupbystrictbiosecuritymeasurestopreventre-introductiontothenaïveandfullysusceptibleherd
Diagnosis and treatment
• Testscanbecarriedoutforthevirus,forexample polymerasechainreaction(PCR)orantigenELISA.Itcan beusefultoperformserologyonagroupoffivetoten, eightmontholdhomebredanimalsasachecktestto classifyaherdascurrentlyactivelychallengedbyBVDor currentlyfree.SeeCattleHealthCertificationStandards (CHeCS)formoreinformationatwww.checs.co.uk
• Persistentlyinfectedcalvesmayappearclinically normalbutarecommonlystuntedorthinduetotheir susceptibilitytobacterialinfectionsuchaspneumonia. Twopositivebloodsamplestakenthreetofourweeks apartarerequiredtoconfirmpersistentvirusinfection. Thesecattlehaveoftenbeentreatedseveraltimes fordigestiveandrespiratoryinfectionsandshouldbe disposedofastheyactasasourceofBVDinfection
CalvesbornofinfecteddamsmaybepersistentlyinfectedwithBVD.
YearlingcalvesmayappearpoorlythrivenincomparisonwiththeirherdmatesduetopersistentinfectionwithBVD.
Calvesmaybebornwithdefectsofthenervoussystem,typifiedbyalowheadcarriageandwidestance.
CowsintroducedtoaherdfromoutsidemaypresentaBVDrisk.Stringentbiosecurityisessentialtopreventinfection.
Bovine Viral Diarrhoea(BVD) Bovine V
iral Diarrhoea (BVD
)
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Severediarrhoeaorcalfscoursisoneofthemostcostlydiseaseissuesaffectingbeefenterprises.Itisamajorcauseofcalfmortalityandleadstosignificantfinanciallossesduetotheseveregrowthcheckinrecoveringcalves.
Thefollowingarethemorecommonandimportantvariantsofcalfscours:
• Rotavirus infection (most common) Infectioncancauseacompleterangeofclinical
signs,fromnoobservedabnormalitytoseverediarrhoeaanddehydrationwithhighmortality.
• Coronavirus diarrhoea Infectioncanprogressrapidlytoweakness,
recumbency,severedehydrationanddeath.
• Enterotoxigenic E. coli Incidenceislow(1%ofscouringcalves)butlosses canbehigh.Suddenonsetofscourisaccompanied
byabloatedappearance.
• Cryptosporidiosis Diarrhoeaiscausedbythephysicallossofabsorptive
areafromthesmallintestineandincreasestheseverityofotherpotentialinfections.Dehydrationtendstobemild,butcalvesloseconditionovertwotofivedaysandhaveadulltucked-upappearance.
• Coccidiosis Causedbysingle-celledparasites,calledcoccidia.
Coccidialspeciesthatcausediseasedamagethecellliningofthelargeintestine,resultingindiarrhoea.
• Salmonella MostcommonlyS.dublinisassociatedwith
producingacuteorsub-acuteillnessincalves.
Costs and implications
Financiallossesfromcalfscourscanbecrippling.Mortalityratescanbeveryhighwithcertaininfections,butalsosignificantisthecostoftreatment(labour,drugs,etc),andtheimpactofseveregrowthchecksoncalvesthatsurvive.
Risk factors and susceptibility
Allyoungcalvesarepotentiallyatriskofinfection,butthefollowingwillincreasethelikelihoodofdiseaseoccurring:
• Historyofspecificinfectionontheunit
• Replacementsfromanotherunit
• Inadequatecolostrum
• Poorstandardsofhygiene
• Rotavirusmostcommonlyaffectscalvesat 8-14days
• Coronaviruscausesdiarrhoeaincalvesupto 20daysold
• EnterotoxigenicE.colitypicallyaffectscalves agedonetothreedays
• Cryptosporidiosisismostcommonincalves 10-21daysold
• Coccidiosisisparticularlycommonincalves betweenthreeweeksandsixmonthsold
• Salmonellausuallyaffectscalvestwotosix weeksofage
Early identification
Earlysignsareasfollowsforthemaindiseases:
• Rotavirus Reluctancetostandandsuck,milddepression,
salivation,quicklyfollowedbyacuteonsetofdiarrhoea(wateryyellow/greenfaeces).
• Coronavirus Depression,reluctancetosuckandfaeces
containingmucusandmilkcurds.
• Enterotoxigenic E. coli Profuseyellow/whitediarrhoeacausingrapid
andseveredehydration.Calvesquicklybecomerecumbentandbloated.
• Cryptosporidiosis Profuseyellow/greendiarrhoeawithmucuspresent.
• Coccidiosis Awaterydiarrhoeaoftenaccompaniedby
straining,mucusandblood,depression,lackofappetiteandweightloss.
Diarrhoea (calf scours)
6 7
• Salmonella Apastydiarrhoeaoftenwithbloodandshredsofmucus
fromtheintestinewithanoffensiveodour.Calvescanrapidlybecomedehydrated,collapseanddie.
Prevention and control
• Management Theriskofallformsofcalfscourscanbeminimised
byensuringcalvingareasarecleanandwell-bedded,preferablymucked-outbetweencalvings.
Calvesshouldhaveatleast10%oftheir bodyweight(usuallyaboutthreelitres)as colostrumideallywithinsixhoursofbirth.
Inthecaseofcryptosporidiosis,wheretheparasite canremainintheenvironmentformonths,itis
importanttoavoidusingthesamefieldsforcalvingandtomovenewbornanimalsimmediatelytocleanpasture.
• Vaccination Annualvaccinationofpregnantcowswitha
combinedrotavirus,coronavirusandE.coliK99vaccineprovidesvaluableinsurance.Protectiveantibodiesarepassedoninthecolostrum.
Diagnosis and treatment
Diagnosisfromsymptomsoutlinedaboveand/orthroughlaboratoryanalysisoffaecesshouldbecarriedoutbythevettodeterminethecause(s)ofdiarrhoea.
Treatment of severely scouring calves:
• Isolateinawell-beddedpen
• Feedonetotwolitresoforalelectrolytetwotofourtimes aday(stomachtubeonceandconsultvetifcalveswill notsuckthroughateatwithintwotofourhours)
• Ifdehydratedcalvescannotstandunaided,intravenous fluidsshouldbeadministeredbythevet
• Antibioticinjectionsshouldbeusedfor concurrentinfections(egnavelill)
• Ascalvesrecover,alternatemilkandelectrolyte solutioneverytwotofourhours
• Offerfluidsbyteatasactivesuckingisanindicator ofimprovement
Milddiarrhoeaorcalfscour.
Moderatediarrhoearequiresoralrehydrationsolutiontocorrectdehydration.
Severediarrhoea.
Affectedcalvesrapidlybecomedehydratedandrecumbent.
Diarrhoea (calf scours)D
iarrhoea (calf scours)
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InfectiousBovineKeratoconjunctivitis(IBK),alsoknownasPinkEyeorNewForestDisease,isahighlycontagiousdiseasecausedbythebacteriaMoraxellabovis.Itspreadsrapidlyduringthesummerandismorecommonlyseeninyoungstockthanadults.
BovineIritis,alsoknownas‘SilageEye’,isacommoncauseofinflammationofthemiddlelayeroftheeye.Itcanoccurincattleofallagesfedbaledsilage/haylage.
CancerEye(OcularSquamousCellCarcinoma)isuncommoninnorthernEurope.Thesecancerousgrowthstypicallydevelopfromthethirdeyelid(themembraneofthelowereyelid)followingprolongedexposuretosunlight.
Costs and implications
Lesionsinandaroundtheeyeareverypainfulandwilldisruptgrazing,causingpoorperformanceandweightloss.Theycanalsocausetemporaryblindnesswithaffectedanimalswanderingaboutaimlessly.
Risk factors and susceptibility
FliesactasmechanicalvectorsforM.bovis.Foreignbodiessuchasdust,grassawnsorsmallbitsofensiledgrassstalk,cancauseBovineIritis.
Early identification
• IBK ThefirstsignsofIBKareobvioustearstainingof thefacewithpusmattingthelashesandhair belowtheaffectedeye.Animalsfinditpainfulto beindirectsunlight.
Spontaneousrecoverymayoccurinmildcases afterthreetofivedaysandtheanimalswillbe betteraftertwoweeks.Inseverecases, ulcerationmayleadtoperforationofthesurface oftheeye(cornea).
• Bovine Iritis Initialsignsincludeexcessivetear-staining, blinkingandforcedclosureoftheeyelids.
Abluish-whiteopacityisusuallyseenonthe corneawithintwoorthreedays.Thiscanturn yellowaspusaccumulatesbeneath.These lesionscantakeseveralweekstoclearwithout treatment.
• Cancer Eye Cancerousgrowthsmayirritatetheeyesurface
leadingtosecondarycornealulcerationandinfectionleadingtoeyelidclosure.Thereisusuallyadischargeduetomechanicalirritationoftheeye.
Eye conditions
8 9
Bovineiritisischaracterisedbyabluish-whiteopacityonthesurfaceoftheeyeball.
Prevention and control
• IBK OutbreaksofIBKcanoccurafterthe introductionofpurchasedstock.Allnewcattle shouldbeinitiallymanagedseparatelyasone groupawayfromthemainherd.
Flycontrol,usingeartagsandpour-on insecticides,isneverabsoluteandrepeated treatmentsarecostly.Developmentofimmunity followinginfectionisvariable.
Injectionofallat-riskcattlewithasingle intramuscularinjectionoflong-actingantibiotic couldbeconsideredinsevereepidemics.Discuss theoptionswiththevet.
• Bovine Iritis Rollingoutbig-balesilageratherthanplacingin ringfeederswillpreventcattleburrowingtheir headsintothebale,butthismaybe impractical.
Attentiontodetailwhenbalingandwrapping andensuringgoodconditionsforfermentation, shouldlimitcontaminationwithListeria monocytogenes,thebacteriawhichcausethe problem.
However,abaleleftexposedtotheairfor severaldaysbeforebeingeatenup,providesan idealenvironmentforL.monocytogenesto multiply.Goodbalemanagementatfeedout isvital.
• Cancer Eye Selectcattlewithpigmentedskinsurrounding theeyelidsasthesearelesslikelytosuccumbto cancereye.
Lashesmattedwithpusindicateaneyeinfection.
YellowpusaccumulatesintheeyewithBovineiritis.
Cattleeatingsilagefromringfeedersareatriskofeyeinjuryleadingtoinfection.
Whiteheadedcattlearemoreatriskofcontractingcancereye.
Eye conditionsEye conditions
9
Hypomagnesaemiaisacommonmetabolic/feedingrelateddiseaseofolderbeefcows(fourthcalvingorolder),butoccasionallycanaffectyoungercattle.Itisoftenfatalifnotdetectedwithinhoursandtreatedcorrectly,soshouldbeconsideredaveterinaryemergency.
Theconditioniscausedbylowbloodmagnesiumconcentrationsresultingfromseasonaldeficienciesingrazedgrassandismostcommonincowsthathavebeencalvedforonetothreemonths.Drycowscanalsobeaffectedifnotreceivingsupplementaryfeed.Hypomagnesaemiacanpotentiallyaffectnumerouscowsinaherdorgroup.Stressfactorssuchasbadweatherorhandlingcancauseclinicalcaseswherethereisanunderlyingproblem.
Affectedcowsaretypicallyfoundlyingwiththeheadthrownbackandmaybethrashingwildly.Cowsmayappearquietattimes,buthandlingusuallyleadstofitting.
Costs and implications
Thelossofasucklercowexceeds£1000.
AllsuddendeathsinadultcattlemustbereportedtothelocalAnimalHealthOfficeandtestedforanthrax.Oncetestsprovenegative,furthertestingiscarriedouttoestablishmagnesiumconcentration.Bloodsamplingofothercowsinthegroupisrecommendedtoestablishherdstatus.
Risk factors and susceptibility
• Lushspringgrazingparticularlyinrecently turned-outspringcalvers
• Autumngrazingforautumncalversparticularly afterstormyweather
• Cowsonetothreemonthspostcalving(fourth calvingonwards)
• Drycowsnotonsupplementaryfeeding
Early identification
Cowswithlowbloodmagnesiumconcentrationsmayappearnormaluntilstressfactorscausetherapidonsetof‘staggers’.
However,thefollowingsignsmayprovideanearlywarninginsomecases:
• Restlessnessandexcitability
• Unsteadiness
• Tremorsoftheskinovertheshoulders
• Eyelidtremors
Hypomagnesaemia (grass staggers, grass tetany)
Feedingmineralsad-libisnotareliablewaytoensureallcowsinagroupreceiveadequatemagnesium.
10 11
Prevention and control
• Daily intake of magnesium
Thisisessentialascowsareunabletostoremagnesiuminthebody.
Feedingcattleconcentratescontaininganappropriatemagnesium,supplement(1-2kg/cow/day)isthemostreliablemethod.
Home-mixedrationsshouldbesupplementedwithmagnesiumasmanystraightsaretypicallydeficient.
Ad-libmineralsarenotareliablesourceofdailymagnesiumforallcowsinagroup.Themostreliablemethodofcontrolistogiveamagnesiumbolus.
• Supplement grazing with straw
Goodqualitybarleystrawfedad-libhelpsslowtheflowoflushgrassthroughthegutandaidsmagnesiumabsorption.
• Avoid potassium fertilisers
Potassiuminterfereswithmagnesiumabsorptionandshouldnotbeincludedincompoundfertilisersspreadontograsslandduringriskperiods.
Diagnosis and treatment
Diagnosisisbasedonclinicalsignsandcanbeconfirmedthroughbloodsampling.
Symptomsofhypomagnesaemiashouldbetreatedasaveterinaryemergency.Fittingcowscanbesedatedfirstbytheattendingvet.Treatmentwilltypicallyinvolveintravenousinjection(byvet)administeredslowly,followedbyfurtherinjectionsatseveralsitesusingamixturecontainingsmallamountsofmagnesiuminacalciumsolution.
Itisessentialtodealwiththeriskofhypomagnesaemiaintheremainderofthegroup(seeabove).
Hypomagnesaemia (grass staggers, grass tetany)
Ifnotdetectedwithinhoursofonset,hypomagnesaemiaisoftenfatal.
Adverseweatherisoneofthestressfactorsthatcanleadtohypomagnesaemia.
Hypomagnesaemiaisaveterinaryemergency.
Turn-outontolushpastureisacommonfactorinvolvedinhypomagnesaemia.
Hypom
agnesaemia (grass staggers, grass tetany)
11
Johne’sdiseaseisaslowlyprogressinggutinflammationinadultcattlecausedbyasubspecies(paratuberculosis)oftheorganismMycobacteriumavium(MAP).Itischaracterisedbyprogressiveweightlossandchronicdiarrhoea,butdiagnosisandcontrolareparticularlydifficult.
Costs and implications
Infectedherdsmaysufferannualcullingormortalityratesof1-5%.
Lossesduetosub-clinicaldisease,includingweightlossandpoorfertility,arealsosubstantial.
Thereisnoeffectivetreatmentandanimalsmustbeculledassoonasadiagnosisisconfirmed.
Risk factors and susceptibility
ClinicalcasesofJohne’sdiseasearenotusuallyseenincattleuntiltheyarethreetofiveyearsold,althoughyoungercasesarepossible.Theorganismispassedontoyoungercattlebyolderinfectedcattleandthereisthenalongincubationperiod.
Thediseasecanbetransmittedinthefollowingways:
• Pickedupfrominfectedfaecesfoundon contaminatedteats,feedstuffsorwatertroughs
• Passedtonewborncalvesinthecolostrumof infecteddams
• Passedfromheavilyinfecteddamstodeveloping calvesintheuterus
Infectedanimalsmayshedcausativeorganismsintheirfaecesforoverayearbeforeclinicalsignsappear.
Early identification
• Diarrhoeaandweightlossincattlethreeto fiveyearsold,despitenolossofappetiteandan absenceoffever
• Signscanappearfollowingastressfulevent,such ascalvingortransportation
Prevention and control
Johne’sdiseaseisdifficulttocontrolduetothelongincubationperiodandthefactthatanimalswillpassinfectiononlongbeforetheyshowclinicalsigns.Diagnosisisalsounrelieable,particularlyintheearlystagesofthedisease.
Practicalcontrolmeasurestolimitlossesinclude:
• Rapidcullingofdiseasedanimals
• Reducingtherisksoffaecalcontaminationof food,waterandpastureeg,raisefeedorwater
troughs,avoiduseofsurfaceorpondwaterfordrinking,avoidspreadingfarmyardmanureonpastures
• Notusingcalvesfrominfecteddamsas replacements
• Onlyrestockingfromaccreditedherds especiallywhenrestockingbulls
Johne’s disease (paratuberculosis)
12 13
Johne’s disease in cattle 1997-2009
• Vaccination–maybeacosteffectiveoption forcommercialbeefherdsrearingtheirown replacements,asitdoesreduceclinicalcasesand overalllosses.However,itwillnoteradicatethe diseaseandavaccinewouldneedtobeimported intotheUKunderlicence.
Keypoints:
• Inoculationmusttakeplacebeforecalvesare onemontholdandpreferablyinthefirstweek
• Inoculationisgiveninthebrisketareaanddoes produceaconsiderablelocalreaction
• Vaccinationisnotanoptionforherdsthatare buyinginreplacements
• VaccinationcomplicatesreadingoftheTBskintest
• Monitored-freeherd–thisrequiressubstantial commitmentbythefarmer,vetandlocal laboratory.
• Strategyisbasedontheidentificationandremoval ofinfectedanimals
• Bloodtestingand/orfaecalexaminationisdone everysixtotwelvemonthswithslaughterof
positivecases
• Twoconsecutiveherdnegativeswillindicate monitored-free
• Strictbiosecuritymeasuresarerequiredtoprevent re-introductionofthedisease
Diagnosis and treatment
ThereisnosinglereliabletestforconfirmingJohne’sdiseaseduringitsearlystages.Inpracticaltermsdiagnosisisbestachievedthroughacombinationofbloodtestsandfaecalexamination.
Thereisnoeffectivetreatmentandanimalsmustbeculledassoonasadiagnosisisconfirmed.Itisrecommendedthattheprogenyofinfectedcowsarenotkeptasbreedingreplacements.
Contaminationofdrinkingwaterwiththefaecesofinfectedanimalsaidsspreadofthedisease.
ProgressiveweightlossandchronicdiarrhoeaarethemainsignsofJohne’sdisease.
Grosslyinfectedenvironmentsshouldbeavoided.
AcleancalvingenvironmentisakeypointincontrollingthespreadofJohne’sdisease.
Johne’s disease (paratuberculosis)Johne’s disease (paratuberculosis)
13
Lamenessresultingfrompainand/orincapacityinthefeetcanresultfromanumberofinteractingfactorsintheenvironmentofcattle.Itismostproblematicalwhenaffectingastudbullorbreedingcowsduringthebreedingseasonandisaseriouswelfareissueinalllivestock.
Footlamenessisusuallyduetoanyofthefollowingconditions:
• ‘Foulofthefoot’anddigitaldermatitis(bacterial infectionbetweentheclaws)
• Hyperplasia(excessskingrowthbetweenthe claws,whichishereditary)
• Soleabscesses/whitelinedisease/solarulceration (impactionbydirt,smallstones,foreignbodies)
• Sandcrack(verticalfractureofthehoofwall)
• Overgrowth(elongationofthefoot)
• Corkscrewclaw(hereditary)
Costs and implications
Lamecattleareunproductivecattle,whetherbreedinganimalsorfatteningstock.
Weightlossisacommonconsequenceingrazingcattle,withdelayedheatandpoorconceptionapossibilityinsucklercows.
Infertilityislikelytobethesinglebiggestcostimplication.
Common causes and consequences
• Foul of the foot/digital dermatitis Thistypicallyoccursasasuddenonsetof lamenessandtheanimalonly‘toes’itsfoot totheground.Itisusuallytheresultofwetdung andmudsofteningtheinterdigitaltissueand sharpstonescausingwoundsthatallowbacteria toinfectthedeepertissues.Reservoirsofinfection cansurviveinwetareasaroundgateways.
Thelesionappearsasawideningofthe interdigitalspacewithswellingprogressingup thelegasfarasthefetlockjoint.Thereisusually abreakoftheskinwithdamageoftissue betweentheclaws.
Digitaldermatitisisthoughttobecausedby atypeofbacteriacalledatreponeme.Ittypically producesaredswollenlesionbetweentheclaws oftheheel,(‘hairyheelwarts’)butcaninfect andcomplicatethehealingofmanyothertypes oflameness.Itisamajorprobleminthedairy industryandalsoisemerginginbeefherds.
• Hyperplasia Thishereditaryconditionappearsasexcessskin growthatthefrontoftheinterdigitalspaceand
ismostcommonlyseeninthehindlegsofbulls.Lamenesscanresultfromsuperficialinfection.
• Sole abscesses/white line disease/solar ulcer Anysharpobjectcanpenetratethesoleand
causeanabscessthatistypicallyrecognisedasablackmarkoverlyingthepus.
Impactionofdirtandsmallstonesinthewhite linecanresultinwhitelineabscesses.Lesions areusuallyfoundintheouterclawofthehind foot,ontheoutsideborderclosetothejunction withtheheel,asthisiswherethereismost physicalstress.
Ifleftuntreated,infectioncanextendupthe hoofwallanderuptatthecoronaryband.
Soleulcerscanbecausedbyexcessivestanding onconcreteespeciallyinthepost-calvingperiod. Althoughmoreofanissueinthedairyindustry itcanbeanissueincubicle-housedbeefcattle.
• Sandcrack Thisisaverticalfractureofthehoofwallof
variabledegreesbetweenthecoronarybandandthebottomofthewall.Thedepthofthelesionvariesandpusmayormaynotbepresent.
Excessivedryingoutofthehoofhornduring summermonthsisthoughttobethecauseofthis condition,thoughthisisuncertain.
• Overgrowth Thisisanelongationofthefoot,especially
affectingthehindfeet.Theconditionreducestheweight-bearingsurfaceofthefootandinthelaterstagesthetoebendsupwardsandnolongertouchestheground.
Lameness
14 15
Lameness
15
Overgrowthistypicallycausedbyalackofnatural wearwhencattlearehousedinstrawyards.
• Corkscrew claw Aheritableconditiontypicallycausingtheouter
clawofthehindlegtobetwisted.
Treatment
Alllamecowsshouldbeattendedtopromptly,withveterinarytreatmentrequiredwhenthecauseofthelamenesscannotbedeterminedand/orwhenthelamenesspersistsaftertreatment.
• Foul of the foot/digital dermatitis Itisessentialtolifttheanimal’sfoottocheckfor
impactedforeignbodies,cleanthefootandspraythewoundwithoxytetracyclineaerosol.Aninjectionwithstandardpenicillinwillusuallycuretheinfection.
Preventionisbyregularfootbathingandimproved hygiene.Disinfectionofhoofknivesby foot-trimmerstopreventinter-herdspreadis importantandfootbathingofpurchasedanimals.
• Hyperplasia Treattheinfectionwithoxytetracyclineandif
necessary,injectableantibiotics.Surgicallyremovethegrowthsasalastresort.
• Abscesses/white line disease/solar ulcer Paredownwithahoofknifetoreleasethepus
andremoveallunder-runhorn–thereshouldbenobleeding.Avoiddamagetothesensitivecorium,asthiswilldelaythehealingprocess.Antibiotictreatmentshouldnotbenecessary.Ashoeblockmaybeusedtorelieveweightfromthesensitiveclawwherealargeareaofthesolehasbeenparedoff.
• Sandcrack Removeallaffectedhornbyparingoutashallow‘V’.
Antibiotictreatmentisnotnecessary.
• Overgrowth / Corkscrew claw Correctivefoottrimmingisrequired.
Incasesoffoulofthefoot,theswellingcanprogressupthelegasfarasthefetlockjoint.
Abreakintheinterdigitalskincausedbytheimpactofasharpstone.
Water-loggedgatewayswitholdbricksandstoneprovideanidealenvironmentforbacteriaanddamageanimals’feet,leadingtofoulofthefoot.
Whenabscessesarecorrectlyparedoutthereshouldbepus,butnoblood.
Lameness
Thisdiseaseisacommonanddevastatingconditioncommonlyfoundinwetgrazingland.ItresultsfromtheinfestationoftheliverbytheflatwormFasciolahepatica(liverfluke).
1. Eggspasstopastureviathedung
2. Eggshatchintowater-bornelarvae,whichinfect watersnails
3. Larvaedevelopintoyoungflukebeforeleaving thesnailwhilststillinthewater
4. Youngflukeareeatenbylivestockgrazing wetlands
Costs and implications
Severelyaffectedcattlebecomeweakandemaciatedandunabletostand,withsuddendeathapossibility.
Eveninlessseverecases,weaknesscausedbyliverdamagemayleadtoanincreasedincidenceofmetabolicandinfectiousdiseases,particularlyincowsinlatepregnancy.Birthofweakcalvesislikely,particularlyincowsonmarginalwinterrations.
Risk factors and susceptibility
• Allgrazingcattlearesusceptibletoliverfluke
• Eggsfromaninfectedanimalcancompletethe lifecycleandre-infectgrazinganimalsina
minimumof20weeks
• Risktendstobeassociatedwithwetpastures, wherethereissufficientmoistureorstanding
watertosupportthesnail
• Exceptionallywetweather,orsuccessivewet summers,canincreasetheriskinpasturesnot
previouslyidentifiedwiththedisease
• Infestedsheepbroughtontoafarmforover-winter grazingwillcontaminatepastureandincrease
therisktocattleduringthefollowingsummer/autumn
Early identification
Thefollowingsignsmayindicateliverflukeinfection:
• Persistentdiarrhoea
• Chronicweightlossdespiteadequatefeeding
• Anaemiainseverecases
Liverflukeiscommonlyconfusedwith:
• Poornutrition(whereitisawholeherdorgroup problem)
• Johne’sdisease(severalcowsinagrouporherd)
• Salmonellosis(severalcowsinthegroupor herd)
• Parasiticgastroenteritis(wholeherdorgroup problem)
Liver fluke (Fasciolosis)
1.4.
2.3.
Abovineliverwithenlargedbileductsduetoflukeinfection.
16 17
Prevention and control
Fencingoffwetareaorcarryingoutdrainagetorestrictsnailhabitatsaretwosolutions,butthismaybeimpractical–particularlyinextensivelyfarmedareas.Itmayalsobepreventedbyenvironmentalstewardshipprotocols.
Controlusingeffectiveflukicidetreatmentsmaythereforebethebestsolution.Inareaswhereliverflukeisendemic,strategicflukicidetreatmentsshouldbegiveninaccordancewiththeveterinaryherdhealthplan.
• Inhighriskyearstreatat-riskcattleinJanuaryand againinOctober/November
• InlowriskyearsasingleannualtreatmentinJanuary shouldbesufficient
Diagnosis and treatment
Diagnosisintheearlystagesmaybecarriedoutifhighriskconditionsareprevalentandisbasedonraisedliverenzymesinbloodsamplesanalysedbythevet.
Thechronicconditionisidentifiedfromsymptomsoutlinedaboveandmaybeconfirmedthroughtheidentificationofflukeeggsindungsamples,thoughthesemaybescarceanddifficulttofind.Specificantibodytestsforliverflukecanbecarriedout,buttendtobeexpensive.
Effectivetreatmentofallstagesofflukeisachievedwithtrichlabendazole.Nitroxynilandoxyclosanidearelesseffectiveagainstyoungflukesandshouldbeusedinthetreatmentofadultflukes(chronicdisease).Resistancetotriclabendazoleisemergingandsorepeateddoseswithadultflukicidesisoftenmoreappropriateforstrategiccontrolofflukeinbeefcattle.
Improvednutritionofaffectedcattleisessential.
Liverflukeismorecommonlyencounteredinbeefcowsgrazingpoorwetpasture.
Diagnosisofliverflukeisnotsimple.Doesthisbullhaveliverfluke,Johne’sdisease,orsomethingelse?Consultthevet.
Persistentdiarrhoeaisamajorvisiblesymptomofliverfluke.
Chronicweightlossandverypoorbodycondition,despiteanadequateration,isacommonindicationofliverfluke.
Liver fluke (Fasciolosis)Liver fluke (Fasciolosis)
17
Youngcattlegrazingforthefirsttimeareatriskfromlungworm.
Husk(orhoose)iscausedbyinfestationofthebronchialtubesbywhitethreadlikewormsknownaslungworm(Dictyocaulusviviparous).Theconditionischaracterisedbypersistentcoughingandbreathingdifficulties,withlungdamagepotentiallydevelopingintosecondarypneumonia.
Cattlebecomeinfectedbyingestinglungwormlarvaewhilstgrazing.Theseinfectivelarvaepenetratetheintestinalwallandpassviathelymphaticsystemandbloodstreamintothelungs.Inthelungs,theselarvaedevelopintoadultswhichcausetheproblem.Femalelungwormslayvastnumbersofeggsthatdevelopintominutelarvae;thesearecarriedinmucusupthewindpipeandareswallowedandpassoutontothepasture,wherethecyclebeginsagain.
Costs and implications
Initsmostsevereform,lungwormcanresultinsuddendeath.Moretypically,affectedcattlewillsuffermarkedlossofbodycondition(upto10%ofbodyweight),withgrowingcattlelosing20-40kgspotentially.Withlongrecoveryperiodsandthepossibilityofsecondarypneumoniarequiringantibiotictreatment,lossesfromasevereoutbreakingrowingcattlecanaverage£50perhead.
Risk factors and susceptibility
• Allyoungcattle(firstgrazing)
• Adultcattlenotpreviouslyexposedtoinfection andthereforewithoutnaturalimmunity
• Young(firstgrazing)cattleareatgreatestriskif grazingpastureshavebeenrecentlystockedwith
oldercattle
• Autumngrazingconditionsaretypicallymost favourabletothedevelopmentandsurvivalof heavylungwormlarvaeinfestationsonpasture
Early identification
Thefollowingsignsmayindicatelungworminfection:
• Panting
• Frequentcoughing,especiallyaftershortperiods ofexercise
• Reluctancetomove
• Standingwithheaddownandneckextended, oftengaspingforbreath
Lungworm (husk or hoose)
18 19
Prevention and control
• Immunitythroughnaturalexposure–cattleexposed tolunginfectionthroughgrazingmoderately infestedpasturesallowstheanimaltodevelop immunity.Thismustbecombinedwithstrategic wormingtreatmentduringthegrazingperiodto preventthediseasedeveloping
• Immunitythroughvaccination–vaccinationpriorto firstgrazingshouldprovideimmunityforsixmonths. Thiscosts£5-£7peranimalandincombination withgoodmanagementpracticeisthebest insuranceagainstlungworm.
Itreliesonalowdoseearlyinseasonwhich stimulatesimmunityafresheachyear.Avoid overworrmingearlyintheseasonaslungwormcan alsostrikeduringlategrazing.Discussastrategy withtheveteachyear.Diagnosis and treatment
Diagnosisisbasedonclinicalsignsoutlinedaboveandmayalsobeconfirmedthroughlaboratoryanalysisofdungshowingthepresenceoflarvae.
Whenthediseaseisidentified,promptwormingtreatmentisessential,usingaproductrecommendedbythevet.Antibiotictreatmentmayberequiredwheresecondaryinfectionhasoccurred.
Severelungworminfection.Notetheextendedneckandpainfulexpression.
Severelungworminfectionandsecondarypneumonia.
Respiratorydistressisawelfareconcernincasesofseverelungworminfection.
Notetheabsenceofdischargefromtheeyesandnostrilsincasesoflungworminfection.Frequentcoughingisthemostimportantclinicalsign.
Lungworm (husk or hoose)
Whitethreadlikewormsinfestingthelung.
Lungworm
(husk or hoose)
19
Overrecentyears,severalvirusestransmittedbyCulicoidesmidgeshaveemergedinEuropeanlivestock,perhapsassociatedwithclimatechange,leadingtosignificanteconomiclosses.Thetwomaindiseasestoaffectbeefcattleare:
Bluetongue virus (BTV)andmorerecently
Schmallenberg virus (SBV)
Allcattlearesusceptibletothediseaseiftheycomeintocontactwiththebitingmidgeresponsibleforcarryingthevirus.Actionstopreventboththesediseaseshaveshownlittleimpact.However,thefollowingaresuggestedoptions:
• Identifyanddestroymidgebreedingsites(dungheaps,dampareas,etc)
• Usemesh(impregnatedwithinsecticide)topreventmidgesenteringbuildings
• Applypour-oninsecticidestocattle
• Strictbiosecurityandquarantineofallcattleandsheepbroughtontothefarmareessentialelementsinthecontrolandpreventionofalldiseasesincludingbluetongue
Bluetongue virus (BTV)
Bluetonguevirusisaviraldiseaseofsheepandcattlethatischaracterisedbylamenessandfeverandcanresultinseriousproductionlossesandmortality.SpreadofthediseaseisdependentuponthepresenceoftheCulicoidesmidgehost.
BluetongueisnowalsowidespreadintheUSAandoutbreaksarebeingreportedinEurope,asfarnorthastheNetherlands.ThefirstincidenceofBTVstereotype8wasreportedintheUKinSeptember2007,inEastAnglia.ThisisconsistentwiththetheorythattransportofmidgesonaircurrentsfromcontinentalEuropeisapotentialthreat.Thereareseveraldifferentstrainsglobally.
Costs and implications
BluetongueisanotifiablediseaseintheUKandsuspectedcasesmustbereportedimmediatelytothelocalanimalhealthoffice.
Thesymptoms,delayedrecovery,susceptibilitytosecondarybacterialinfectionsandpotentialmortalityofcattlemeanthatsignificantproductionlossesareinevitable.
Diseasecostshavebeenestimatedatupto£19/sheepand£17/cowonaffectedfarmsfrom:
• Deaths
• Lossofproduction
• Costofdisposal
• Veterinaryandmedicines
• Labour
Early identification
Thefollowingsymptomsaremostlikelytooccurinaffectedcattle:
• Fever(temperaturesupto40ºC)
• Stiffnessandreluctancetomove,duetoswellingofthecoronarybandatthetopofthehooves
• Nasaldischargeandulcerationsofthemuzzle
• Lacrimation(dischargefromthetearducts)butnoobviouseyelesions
Prevention and control
Vaccinesareavailablethroughthevet.Alwaysfollowmanufacturer’sguidelines.Inthecaseofanoutbreak,Defraprotocolswouldcomeintofocusontheinfectedpremises.
Diagnosis and treatment
• Diagnosisisbaseduponclinicalsignsand/orisolationofthebluetonguevirus
• Thereisnofullyeffectivetreatmentforclinicallyaffectedanimals.Treatmentislimitedtoantibiotictherapytocontrolsecondarybacterialinfections
Midge-borne diseases
20 21
BTV – a continuing threat
WhiletheBTV8virusemergedinBelgiumandtheNetherlandsin2006andspreadrapidlytocentralandwesternEuropeancountriesincludingtheUK,waswellcontrolledbystrategicuseofvaccination,otherstrainsofBTVcontinuetorepresentathreat.Forexamplein2007,BTV1spreadfromtheMaghrebtoSpainandwassubsequentlydetectedinFranceandPortugal.
Schmallenberg virus
Morerecently,Schmallenbergvirus(SBV)wasidentifiedinGermanyinNovember2011.
Schmallenbergvirusprimarilyinfectsdomesticandwildruminantsandcausesclinicalsignsincludingdiarrhoea,moderatehypothermia,decreaseinmilkproductionandanorexiainadultcattle.Sheepandgoatscanbemildlyaffected.Infectionofbovine,foetusesbySBVisassociatedwithabortions,prematurebirthsandstillbirths,diversecongenitalmalformationsandabnormalitiesofthecentralnervoussystem.SchmallenbergvirushasspreadveryrapidlyfromGermanyandtheNetherlandstotheUK,FranceandotherEuropeancountries.
AlthoughSBViscurrentlylessapparentintheUK,thereisevidenceofcontinuedviruscirculationandsuccessfuloverwintering.ItisnotknownhowlongnaturalimmunitytoSBVmaylast,butitappearsthatimmunityinherdsispatchywithsomeanimalsremainingvulnerable.
AcommercialvaccineisavailableanddiscussionwiththevetisimportanttomanagetheongoingriskofSBV.
Bluetonguevirus:Extensiveteatdamagemayoccur.
Bluetonguevirus:Nasaldischargeandsoresmaybevisible.
Bluetonguevirus:Mouthsoresmaybepresentinsomecattle.
Schmallenbergvirus:Calfaffectedbybraindeformities.
Midge-borne diseasesM
idge-borne diseases
21
TheUKiscurrentlydeclaredBTVfree.Anysuspectedcasesofbluetonguevirusmustbereportedquickly.TelephonethelocalAnimalPlantHealthAgency(APHA)Officeimmediately.CalltheDefrahelplinetoobtainthelocalofficenumberon08459335577,orvisitwww.defra.gov.uk.
Parasiticgastroenteritis(PGE)iscausedbythematurationofOstertagiaostertagilarvaeintheabomasum(fourthstomach)andusuallyaffectsgrowingcattleduringtheirfirstsummeratgrass.PGEisnotusuallyseeninadultcattle.
1. Adultnematodesindigestivetract
2. Eggsarelaidindigestivetract
3. Eggsinfaeces
4. Eggshatch,larvaedevelopsintoinfectivestage
5. Hostingestsinfectedlarvae
6. Larvaematuretoadult
Thediseasecanbedividedintotwoforms:
Type I Ostertagiosis
Typicallyseeninsusceptiblecalvesoryearlingsduringthelatesummer/earlyautumnandiscausedbytheingestionandimmediatematurationoflargenumbersofinfectivelarvae.
Type II Ostertagiosis
Resultsfromtheingestionofinfectivelarvaefromautumnonwards,withdiseasebeingcausedlaterinthewintermonthsfollowingdelayedemergenceoftheadultworms.
Costs and implications
Lossesfromasevereoutbreakofparasiticgastroenteritisingrowingcattlecouldreach£50perhead.Thisresultsfrommarkedlossofbodycondition(upto10%)andprotractedconvalescenceresultinginextendedfatteningperiods(uptothreemonths).
Lowcostpreventativeprogrammesareavailabletoallproducers.
Risk factors and susceptibility
Anycattle(usuallygrowingcattleintheirfirstgrazingseason)aresusceptibletoparasiticgastroenteritis,iftheyareexposedtocontaminatedpasturebeforetheyhavedevelopednaturalimmunity.
Circumstancesthatincreasetherisk:
• Whenyoungcalvesaregrazedforthefirsttime onpasturesthathavebeenrepeatedlygrazed
byotheryoungcalves,soabuildupofinfectivelarvaehasresulted
• Whenweanedbeefcalvesaregrazedon contaminatedpastureduringtheirsecondseason
whentheyhavenothadsufficientexposureintheirfirstgrazingseason
• Whenadryearlysummerisfollowedbywet weatherduringAugustandSeptember,resulting
inmassemergenceoflarvaeandingestionbygrazingcattle(TypeI)
Early identification
Type I
• Characterisedbylossofappetiteandsuddenandprofucegreendiarroheainthelatesummer/earlyautumnperiod.Symptomscanaffectmostanimalsinagroupwithinafewdays
Type II
• Diseasesymptomsaresuddenandsevere.Theyareseenduringthelatewintermonthsfollowingdelayedmaturationofthelarvae
Parasitic gastroenteritis (PGE or gut worms)
3.6. 1.
2.5.
4.
22 23
Inspring-calvingbeefherds,earlyseasonpasturecontaminationisingestedbyimmuneadultcows.
SymptomsofPGEincludealossofappetitewithsuddenandprofusegreendiarrhoea.
ItisimportanttokeepdetailedrecordsofgrazingpatternsandpastanthelminticproblemsinordertotailorthebestPGEandlungwormcontrolprogrammeforagivensituation.
ProblemswithPGEcanariseinbeefcattlewhenweanedcalvesgrazecontaminatedpastureduringtheirsecondseason.
Parasitic gastroenteritis (PGE or gut w
orms)
23
Treatment and prevention
Preventionisfarmorecosteffectivethantreatment;planningwormcontrolcansavesignificantamountsofmoney.Formostfarms,wormerswillstillbeanessentialpartofeconomicstockproduction,andstrategicwormeruseneedstobebuiltintothewormcontrolplan.Eachfarmshouldhaveitsownindividualwormplan,basedonfarmmanagement,previouswormhistoryandtypeofstock.
Thereareseveralfactorstobearinmindwhendevelopingtheplan:
• Usepastureeffectivelysothatcattleavoidgrazingcontaminatedpastureduringthepeakseason.Thiscanbeassimpleasmovingcattleontofresh,ungrazedpasture(suchassilageaftermath)justbeforethesummerriseinlarvalnumbers
• Reduceroutinewormingbymonitoring,particularlyfaecaleggcounts(FEC)andandanimalgrowthrates.Thiswillsavemoneyandreducetheriskofresistancedevelopingonthefarm
• Wormathousinginstocksusceptibletohibernatinglarvae
• Donotforgetlungwormcontrol;thisisanincreasingproblemonmanyfarms.Controlmeasuressuchaspasturemanagementarelesseffectiveforlungwormthangutworms,sousevaccinationtocontrollungworms
Larvaematuretoadultinthedigestivetract.
Mostplantsarenotpoisonoustocattle,butafewnotableexceptionswillcauseseriousproblemsifingested.
Ragwort
HighawarenessandcarefulmanagementofpasturesmeansragwortpoisoningisrelativelyrareintheUK.Incidencesusuallyoccurfollowingingestionofthewilted/driedplantinhayorsilage.
Yew
Acommonornamentaltreeoftenfoundinchurchyards.Ingestionusuallyleadstorapiddeath.
Bracken
Ingestionofbrackenoverseveralweekswhenpastureissparsecanbefataltocattle.Deathresultsfrombonemarrowsuppressioncausinglossofbloodcellsandclottingfactors.
Ingestionofbrackenovermanymonths,particularlywhenusedasbeddingmaterialcanleadtotumoursinthebladder,oesophagusandrumen.
Acorns
Thesecanpresentaseriousproblemonpastureswhichhaveoaktreesinthemafterautumnstorms.Tanninsintheacornscauseserious,oftenfatal,kidneydamage.
Water dropwort
Dry,hotweathercandrivecattletograzemarginalareasinsearchoffoodwheretheyencountertoxicplantstheywouldnormallyleavealone.
OneofthemostimportantisWaterdropwort,whichisverycommoninthewestandsouthofEngland.
Cattleareparticularlyatriskafterditcheshavebeenclearedoutwhichexposesthepoisonousroots,oftenreferredtoas‘deadman’sfingers’.
Costs and implications
Plantpoisoningincattleisusuallyfatalincurringthelossofproductiveanimalsandtheassociatedcostsofbringinginorrearingreplacements.
Risk factors and susceptibility
Pasturemanagementshouldreducetherisksofplantpoisoningasmuchaspossible,egbydiggingoutragwort,sprayingbracken,ensuringaplentifulsupplyofnutritiousgrasses.
Early identification
Ragwort
• Chronicweightlossanddiarrhoea• Jaundice• Accumulationoffluidunderthejawandbrisket causedbyliverdisease
Yew
• Noearlysigns.Deathrapidlyfollowsingestion
Bracken
• Weightlossandweakness• Bloodhaemorrhagingfromthenasalpassages andvagina• Deathwithinseveraldays
Acorns
• Constipation/strainingtodefecate• Diarrhoea• Anorexia• Bloatduetotherumennotworking• Renalfailure• Deathwithinfourtosevendays
Water dropwort
• Salivationanddilatedpupils• Breathingdifficulty• Collapseandspasmodicconvulsions• Mostaffectedcattledie
Prevention and control
Ragwort
Controlragwortonpasturebysprayingwithselectiveherbicides,orbydiggingoutthewholeplant.
Yew
Preventaccessbycattlebyfencingoffyewtreesandmaintainingperimeterfencessotheycannotescape.
Plant poisoning
24 25
Bracken
Manyhillfarmshavesubstantialareasofbrackenwherefencing,burningorherbicidetreatmentswouldbeuneconomic.Adequatefeedingshouldensurecattledonotgrazebracken.
Acorns
Removecattlefrompasturewithoaktreesinthemespeciallyafterautumnstormsorheavyacornfalls.
Water dropwort
Supplementcattleonbarepasturesduringdroughttopreventthemgrazingmarginalareas.Movecattleoutoffieldswhereditcheshavebeencleared.
Diagnosis and treatmentRagwort
Diagnosisisbaseduponclinicalevidenceofliverdiseasewithknownexposuretoragwort.
Thereisnoeffectivetreatmentonceclinicalsignsappear.Removecontaminatedfeedanddestroy.
Yew
Causeofdeathcanonlybeconfirmedbyexaminingrumencontentsatpostmortem.
Thereisnotreatment.
Bracken
Inacutecasestreatmentwithbroadspectrumantibioticsisgenerallyunsuccessful.
Acorns
Diagnosisisbaseduponclinicalsignsandexposuretoacorns.Confirmationbypostmortem.
Thereisnospecifictreatmenttocuretheproblem.Supportivetreatmentincludesgivinglargevolumesofintravenousfluidswhichareprohibitivelyexpensive.
Water dropwort
Diagnosisisbaseduponevidenceofplantshavingbeengrazedorrootsexposedbyditching.Confirmationbypostmortem.Thereisnospecifictreatment.Ifpoisoningissuspectedremoveallcattlefromareaswheretheplantgrows.
Cattlethateatragwort,brackenoracornswillsufferexcessiveweightloss.
Diarrhoeaisasignofpossibleragwortpoisoning.
Removecattlefrompastureswithoaktreesintheautumn.
Longtermingestionofbrackencanbefataltocattle.
Plant poisoning
25
Respiratorydiseaseincattleisaninteractionbetweentheinfectiousagentoragents(bacteria,virusorboth),theenvironmentandtheimmunestatusoftheindividualanimal.Diseasecanresultfromprimaryviralinfection,orfromsecondarybacterialinfectionthatresultsfromviraldamagetothedefencemechanismsoftheupperrespiratorytract.Therearealsobacteriathatcauserespiratorydiseasethroughprimaryinfection,suchasmannheimiacausing‘pasteurellosis’whichcanbeassociatedwithsuddendeath.
Themainpredisposingviralcausesofrespiratorydiseaseincattleare:
• IBR(InfectiousBovineRhinotracheitis)
• BRSV(BovineRespiratorySyncytialVirus)
• PI3(Parainfluenza3Virus)
Costs and implications
RespiratorydiseaseisestimatedconservativelytocosttheUKcattleindustry£60millioneachyear.Thisiscalculatedonthebasisof£30formildcasesrisingto£500whentheanimaldies.
Lossesresultfrommortalityandtreatmentcosts,butmostimportantlyfromweightlossduringillnessandoftenthroughdelayedrecovery.
Risk factors and susceptibility
Respiratorydiseasecanaffectallagesofcattlebutismostcommonlyseeninyoungeranimals.
Factorspredisposingcattletorespiratorydiseaseincludethefollowing:
• Poorventilationand/ordraughtsinbuildings
• Extremesoftemperature
• Stresscausedbymovement,mixingofstock, housingorexcessivehandling
• Generalpoormanagement,poornutrition, poorhygiene
Early identification
Increasedrectaltemperatureisveryoftenthequickestandmostaccuratemethodofidentifyingaffectedcattlewithinagroup.
IBRClinicalsignstypicallyappeartwotothreeweeksafterhousingorotherstressfuleventssuchascalving.Affectedanimalsdonoteat,areverydepressed,slowtoriseandstandwiththeirheadlowered.Apusdischargeiscommonlyproducedfromtheeyesandnostrils.
BRSVClinicalsignsarehighlyvariable.Insevereoutbreaksanimalsmaybefoundstrugglingtobreatheandcanrapidlydeteriorateanddie.Infectionmayoccurwithnosignsofrespiratorydistress.
Respiratory disease (pneumonia)
26 27
Prevention and control
• Husbandry Attentiontogeneralhusbandryisthefirstimportant
controlmeasureinrelationtorespiratorydisease,especiallyensuringbuildingventilationdesignprovidesasuitableenvironment.Reducingstockingdensitywillusuallyreducethediseasepressurewhenanoutbreakoccurs.
• Vaccination VaccinesareavailabletopreventIBRandBRSV.
Allbeefunitsshouldseekveterinaryadviceonthestrategicuseofvaccinationaspartoftheirherdhealthprogrammes.Laboratoryconfirmationofcause(s)maybenecessarybeforeembarkingonavaccinationprotocol.
Diagnosis and treatment
Rapidandaccuratediagnosisofthecause(s)ofrespiratorydiseaseisessentialsothatstepscanbetakentopreventfurtherandfutureincidence.
Choiceofantibiotictreatmentiscriticalandwillbedeterminedbythevet.
Aswellasantibiotictreatmentitisimportanttominimiselongtermlungdamagethroughtheuseofanti-inflammatorydrugs.
AcalfsufferingfromrespiratorydiseasecausedbyBRSV;itappearednormal12hoursearlier.
Selectingcattlefortreatmentonthebasisofraisedrectaltemperatureisoftenthemostcosteffectivewaytodealwitharespiratorydiseaseoutbreak.
Lungdamagecommonlyimpairsfutureperformanceinnon-fatalcases.
Inadequateventilationincattlebuildingsiscommonandincreasestherisksofrespiratorydisease.
Respiratory disease (pneumonia)Respiratory disease (pneum
onia)
27
PrimarybacterialrespiratorydiseasecausedbyHistophilussomniandMycoplasmabovisisemergingasamajorproblemintheUK.Therearenovaccinescurrentlylicensedagainstthesepathogensandgoodhygieneandmanagementregardingventilationandstockingratesareimportant.
Septicaemiaisabacterialinfectionthatthreatensbeefcalveswithinthefirstsixdaysoflife.Jointilloftendevelopslaterincalvesthatsurvivetheinitialinfection.
Calvesarevulnerablewhenbornintoacontaminatedenvironment.Bacteriatypicallyinfectthecalfviathetonsil,upperairwayorgutand,althoughthenavelisnotamajorentrypointforbacteria,localinfectionwillcausenavelill,whichmaydevelopintoperitonitis(widespreadabomasuminfection).Thereisanincubationperiodofaround24hoursbetweenfirstinfectionandoutwardsignsandthediseasecanleadtodeathwithinaslittleaseighthours.
Costs and implications
Thelossofyoungcalveswillpotentiallyunderminetheprofitabilityofanybeefenterprise.Avoidance,byensuringadequatecolostrumintake,isthereforehighlycosteffectiveuseoftime.
Newborncalfinfectionssuchasjointillandnavelillareextremelypainfulandareeasilyprevented.
Risk factors and susceptibility
Therisksofinfectionareheightenedbypoorhygienearoundcalvingtimeandfailuretoensurethecalfreceivesadequatecolostrumwithinthefirstsixhoursoflife.
• Poorhygiene
• Insufficientcolostrumintakewhichmayresult fromanyofthefollowing:
• Small,weakandsicklycalveseg,premature, twins
• Calvesrenderedweakfollowingadifficult calving
• Cowswithinsufficientorpoorquality colostrumduetopoornutritionordisease
• Downercowsaftercalvingeg,milkfever
Early identification
Thefollowingsignsareanindicationthatcalvesmaybeinfected:
• Calvesareinitiallydullandlethargic
• Calveshavefailedtosuckandcowsbecome anxious(bellowing,udderfullwithmilk)
• Coldextremities
• Salivationandyellowmucoiddiarrhoea
Prevention and control
Calvesmustingest10%oftheirbodyweightofcolostrum(usuallyaboutthreelitres)withinthefirstsixhoursoflife,otherwisetheyaresusceptibletoinfection.
• Ensureadequatecolostrumintakethrough:
• Addedvigilancearoundcalvingtime,including athoroughcheckthatnewborncalveshave suckedwell
Septicaemia(blood poisoning)
28 29
• Keepingasupplyoffrozencolostrumforuse whennecessary.Ifusingcolostrumfrom
anothercow,besuresheisnotasourceofotherdiseasessuchasJohne’sdisease.Colostrumshouldideallybefedwithabottleandteat,inpreferencetoastomachtube
• Testingforcolostrumintake:
• Theveterinarysurgeonmaybeabletooffertests forpassiveantibodyingestion(colostrumintake)
throughthepracticelaboratory
Stricthygienearoundcalvingisanessentialmanagementfactorinthecontrolandpreventionofsepticaemiaandassociatedconditions.
• Maintainthehighestlevelsofhygieneby:
• Regularlycleaningoutcalvingboxesandusing sufficientcleanbeddingstraw
• Avoidingoutdoorcalvinginpotentiallywetand muddyconditions
• Fullyimmersecalves’navelsinstrongveterinary iodinesolutionsoonafterbirthandagainafter fourtosixhourswhencheckingcolostrumintake
• Movingcowsandnewborncalvesawayfrom heavilyusedcalvingpaddocksassoonaspossible
Diagnosis and treatment
Septicaemiacanbediagnosedbythevetuponclinicalexamination.
Jointillappearsasahot,painful,swollenjoint(s)withobviouslamenessaffectingoneormorelegs.Calvesmaybeunwillingtostandwhenmorethanonelegisaffected.
Rapiddetectionandearlyveterinaryattentionisvitaliftreatmentistobeeffective.Antibiotictherapywilldependonthelikelybacterialcause.Anti-inflammatorydrugsmayalsobeprescribed.
Allcalvesmustsucksufficientgoodqualitycolostrumwithinthefirstsixhoursoflife.
Largeuddersorteatsoftenbecomecontaminatedandcanbeasourceofbacterialinfectiontoanewborncalf.
Ifcalvesrequireartificialfeeding,abottleandteatispreferabletoastomachtube(oesophagealfeeder).
Jointillisoneofthepotentialconsequencesifcalvesdonotreceiveadequatecolostrum.
Septicaemia(blood poisoning)Septicaem
ia (blood poisoning)
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Skinconditionsareusuallycausedbyectoparasites.Producersneedtoidentifythespecificectoparasiteinfectionaffectingtheircattletotreatitappropriately.
TheparasiteswhichcausemostdamagetocattleareLice(Pediculosis),Sarcopticmange,Psoropticmange,Choriopticmange,ticksandmidges.
Therearefivespeciesoflousewhichinfestcattle,classifiedaseitherbitingorsucking.
SarcopticandPsoropticmangeoccurworldwidebutarerareintheUK.Since2007therehavebeenafewcasesofthelatterreportedhere,whereinfestationshavebeenbroughtinonimportedcattle.
VigilanceisimportantasnewcasesareoccurringintheUKandtreatmentsarenotveryeffective.
Choriopticmange,causedbyinfestationwithChorioptesbovis,iscommonlyseeninadultcattleintheUK,towardstheendofwinterhousing.
Ticks(Ixodesricinus)arenotasignificantproblemintheUK,althoughtheycanactasvectorsfortheoccasionalcaseofredwater(Babesiaspp)andtick-bornefever(Ehrlichiaphagocytophila).
Costs and implications
Ectoparasitescauseproductionlossesduetoreducedordisruptedfeedingcausedbyirritationanddamagedhides.
Sarcopticmangecanleadtoweightlossprogressingtoweaknessandincapacityinneglectedcattle.Itcanbetransferredtohumanbeings.Risk factors and susceptibility
Lousepopulationsarehighestincattlekeptindoorsduringwinterandthoseinpoorbodycondition.Spreadoccursbydirectcontact.Thelifecycle–egg,threenymphstagesandadult,takesthreeweeksandallstagesoccuronthehost.Early identification
Heavyinfestationsoflicecauseirritation,causingcattletorubagainstfencesandfeedbarrierstoscratchthemselves,resultinginhairlossusuallyovertheneckandshoulders.
Mangescauseoozingofliquidserumfromthebloodandthickeningoftheskin.
Sarcopticmangethickensovertheneckandcancausesevereirritationsaroundtheanus.InPsoropticmange,theskinthickensovertheneckandalongthemid-lineoftheback.
Choriopticmangeinfestationscharacteristicallyoccuratthebaseofthetail,butinfestationmayspreadtotheudder,scrotumandlimbs.
Skin conditions
30 31
Heavyinfestationsoflicecauseanimalstorubthemselvestorelievetheirritation.
Prevention and control
Biosecuritymeasuresshouldpreventtheintroductionofparasitesoninfestedcattle.Diagnosis and treatment
Carefulinspectionoftheskinusingamagnifyingglasswillidentifyadultlousepopulationsandeggsstickingtohairs.Furtherexaminationunderamicroscopeatx100willdifferentiatetheparticularlicespeciespresent.
Mangecanbeidentifiedviaskinscrapingsunderamicroscope
Choriopticmangeisoftenobservedinfemalecattlebyvetsduringpregnancydiagnosis.
Treatmentusingapour-onsyntheticpyrethroidpreparationsuchasdeltamethrinwillremovealllice.
AninjectableGroup3anthelminticwillremoveallsuckingliceandmorethan98%ofbitinglice.Allcattleindirectcontactwitheachothermustbetreated.
TreatmentforChoriopticmangeisrarelynecessaryaslesionshealspontaneouslywhencattleareturnedouttopastureinthespring.
Skinconditionsareworsewhencattlearehoused–buttheeffectscanalsobeseenwhentheyareturned-outtograss.
Choriopticmangeusuallyoccursatthebaseofthetail.
Mangecausesoozingofliquidserumscabsandthickeningoftheskin.
Thelicelifecyclefromeggtoadulttakesthreeweeks.
Skin conditionsSkin conditions
31
Summermastitisusuallyoccursinnon-lactatingcowsandheifersduringsummer.Itoccasionallyappearsintherudimentaryuddersofyoungheifers,bullsandsteers.
Inbeefcows,summermastitisisoftenseenwherebarrenspringcalvingcowsarekeptforbreedinglaterintheyear,ietransferredfromaspringtoautumn-calvingherd.
Thediseasecanbepresentinbeefcowsthathavestoppedlactatingbeforetheircalfhasbeenremoved.
ThereiswideregionalvariationinincidenceacrosstheUK.
ArangeofbacteriacausetheinfectionincludingArcanobacteriumpyogenes,PeptostreptococcusindolicusandStreptococcusdysgalactiae.
Infectionistransmittedbyheadflies(Hydroteairritans),whichliveinbushesandtrees.Theyonlyflyduringmild,humidconditionsandinlowwindspeeds.Casesofsummermastitistendtobeassociatedwith‘problemfields’nexttowoodsandhighhedges.
Costs and implications
Lossofanaffectedquarteroftheudderreducesfuturemilkproductionbyaround10%,sothesucklingcalfwillsufferandwillnotgrowaswellasexpected.Affectedcowsmayloseupto100kgliveweightandgenerallycommandpoorsalepriceswhensold.
Risk factors and susceptibility
Riskfactorsinclude:
• Grazingpermanentpasturewheremoreflies tendtohatch
• Low-lyingfieldssurroundedbytrees
• Geneticsusceptibilityoftheanimal
Early identification
Supervisionofmaidenandin-calfheifersanddrycowsatpasturemaybesporadicduringsummerandmastitiscanbewelladvancedbeforeclinicalsignsarenoted.
Duringtheearlystagesthereisgradualenlargement,bothinlengthanddiameteroftheteatsoftheaffectedquartersbeforetheheifer/cowbecomessick.Oftenlargenumbersoffliesclusteraroundtheaffectedteatorificecausingconsiderableirritationandtheanimalwillkickfrequently.
Obviousswellingaccompaniesmoregeneralisedsignsofillness,includingisolationfromthegroup,stiffnessandreluctancetowalk,lackofgrazingandrapidlossofbodycondition.
Theaffectedquarterisswollen,hard,painfulandhot.Theuddersecretionisthickandclottedwithfoul-smellinggreen/yellowpus.Affectedanimalscanabortandmaydiewithoutprompttreatment.
Theaffectedquarterisusuallypermanentlydamagedandthecowsoftengivebirthtoweaklycalveswhichoftendie.Thosethatsurviveshouldbegivencolostrumfromanothercow.
Summer mastitis
32 33
Itisimportanttostripoutthelumpymilkifpossible.
Prevention and control
Reduceexposuretofliesbygrazingcowsawayfromsusceptiblefieldsinsummer.Movethemtohigher,moreexposedgroundawayfromclumpsoftreesorhighhedges.
Employflycontrolmeasures(usuallysyntheticpyrethroids),suchasimpregnatedflytags,pour-onpreparationsandsprays.
Drycowtherapyremainsthemosteffectivemeansofpreventingsummermastitisincowsatweaningandinsusceptiblepregnantheifers.
Uselongdurationdrycowantibioticpreparationswithveterinaryadvice.
Takecarewheninfusingintramammaryantibioticpreparationsinheiferstopreventteatdamage.Cattleshouldnotbetubedinwetweatherorinunhygienicconditions.
Sealingtheteatcanal,usingphysicalbarrierssuchmicropore/adhesivetapeandexternalteatsealants,canbeusedtogoodeffect.
Removeanyaffectedcowsfromothercowstopreventthespreadofinfection.
Diagnosis and treatment
Diagnosisisbasedonspottingswollenuddersassoonaspossible.
Veterinarydrugsincludingantibioticsgivenasinjectionsandintra-mammarytubesarerequiredtotreattheinfection.
Strippingthelumpymilkoutoftheaffectedquartershouldbeundertakenasoftenasispractical,butmayberesentedbytheanimalduetothepain,sothereisahighriskofbeingkicked.
Obviousswellingaccompaniesmoregeneralsignsofdistress.
Largenumbersoffliesoftenclusteraroundtheaffectedteat.
Thecalvesofdamswithmastitismayhavetobebottlefedtoensuretheyreceiveenoughmilk.
Drycowtherapy,includingadministeringantibiotictubesisthemosteffectivewaytopreventsummermastitis.
Summer mastitisSum
mer m
astitis
33
Subcutaneous and intramuscular injections
Subcutaneousinjectionsareadministeredinareaswheretheskinisloose,mainlytheneckorbehindtheshoulder.Graspafoldofskinandslidetheneedlethroughtheskinparalleltotheanimal’sneckortrunk.Thismethodwillavoidpenetrationofunderlyingmuscle.Theneedleshouldbeinsertedseveralinchesfromtheoperator’shandtoavoidaccidentalself-injection.Theplungerofthesyringeshouldalwaysbepulledbacktoensurethattheneedleisnotlocatedwithinabloodvessel.
Themainsiteforintramuscularinjectionisthemusclemassoftheneckforwhichtheanimalmustbeadequatelyrestrainedtoavoidhead-buttingorkicking.Alternatively,themusclesofthehindlimbcanbeused.Drawupthesolutionforinjectionintothesyringe.Disconnecttheneedleandholdthehubfirmlybetweenthumbandmiddlefinger.Inserttheneedleintothemuscletothehubwithasharpslapaction.Connectthesyringetotheneedle,drawbacktocheckfortheabsenceofbloodandthenslowlyinjectthecontentsofthesyringeovertenseconds.Donotinjecttooquicklyasthismaycausepaintotheanimal.
Neverinserttheneedlewhenconnectedtothesyringe,asthismakesitmoredifficulttoinserttothecorrectdepthwithasinglemovement.Thesyringehubistheweakestpointandwilloftensnapiftheanimalmoves,renderingthecontentsofthesyringeuselessandcreatingpotentialanimalwelfareandmeatsafetyissues.
Intravenous injection
Thisisthefastestroutefordrugadministration,bypassingabsorption.However,thisisavetprocedureonly.Drugsadministeredintravenouslyincludesomeantimicrobials,nonsteroidalanti-inflammatorydrugsandmineralsolutionsincludingcalcium,magnesiumandphosphorus.
Drenching
Smallvolumesofliquid(lessthan50ml)canbeadministeredbymouthusingadrenchinggun.Theanimalissuitablyrestrainedincattlestocks(notnecessaryforcalves).Theanimal’sheadisheldwiththechinupandtheliquidslowlysquirtedintothemouth.Theanimal’sheadisreleasedonceithasswallowedtheliquid.
Largervolumescanbeadministeredbystomachtube,mostoftenincalvestoadministercolostrumororalrehydrationsolutionbyoesophagealfeeder.Thesefeedersaredesignedsothatthebulbousendcannotbemistakenlypassedintothewindpipe.Thetubeispassedslowlythroughtheanimal’smouthandadvancedwhenthecalfswallows.Donotforcethetube.Afterrepeatedusetheplastictubemaybecomekinkedanditisnecessarytopassitthroughhotwatertosoftentheplasticandenablepassage.
Inadultcattle,restraintincattlestocksorheadyokeisnecessary.Selectthecorrectdiameterstomachtubeforthecow.Anarrowgaugetubemayincreasetheriskofpassageintothewindpipe.Measurethestomachtubeagainstthesideofthecowfollowingthecontourofthelowernecktoapoint30cmbehindthepointofthecow’selbowwhichistheentrypointintotherumen.Facethesamewayasthecowandplaceyourbackagainstthecow’schinwithonearmoverthecow’snosewithyourhandatthemouth.Withyourotherhandpassthestomachtubeintothemouthandguidethetipoverthecow’stonguewithyourotherhandadvancingthetubeintotherumen.Gasisoftenreleasedasthetubeenters.Theanimalshouldnotstrugglevigorouslyandrarelycoughs–suchreactionmayindicatethatthetubehasenteredthewindpipe.Amouthgagoranouterprotectivemetaltubewillpreventthecowchewingthestomachtube.
Best practice
34 35
Further information
• Thevolumeinjectedatasinglesitemustnotexceed thatstatedinthedatasheet
• Onlyadministermedicinesbythestatedroute(s)
• Anaccurateliveweightmeasurementmustbeused eitherbyweighcrateorweighband.Underestimates
ofbodyweightmayleadtounder-dosingandthemedicinenotbeingwhollyeffective.Thiscanpotentiallyalsoleadtothebuild-upofresistance.Thissituationismostlikelywhentreatingagroupofanimalswithawiderangeofweights,wheretheaveragebodyweightisselectedeg,drenchinggrowinganimalswithananthelmintic
• Whenusingmedicineswhicharesuspensions, thoroughmixingisessentialbeforeadministration
• Whenusingthesamebottleofmedicinemultiple times,aneedleshouldbeinsertedthroughtherubber
stopperandleftinplacewithsyringesattachedtothisneedle
Storage of veterinary medicines
Storage
• Storeinaccordancewiththemanufacturer’s instructions
• Refrigerationmustbeavailableandmaintained between2°Cand8°C.Refrigeratorsshouldbefitted
withamax/minthermometertoallowmonitoringofthetemperature
• Thedesignatedstorageareashouldnotbe accessibletothepublic
• Storageareasshouldbecleanandwellventilated witheating/drinkingforbidden
• Datesofdeliveryshouldbeloggedandmarked onproducts.Formulti-useproductsdateoffirstuse
shouldbemarkedontheproduct
Handling
• Directcontactbetweentheskinoftheperson dispensingthedrugandthedrugitselfshouldbe
avoided.Thiscanbeachievedthroughwearingprotectiveclothing,suchasdisposablegloves
• Thedatasheetshouldalwaysbeconsulted
Themainsiteforintramuscularinjectionisthemusclemassoftheneck.Foranintramuscularinjection,inserttheneedleintothemuscletothehubwithasharpslapactionandthenconnectthesyringetotheneedle;drawbacktocheckforabsenceofblood.
Weighcattletoadministratorcorrectdosageofmedicines.
Correctdrenchingprocedureinvolvesfacingthesamewayasthecowandplacingyourbackagainstthecow’schinwithonearmoverthecow’snose.
Amouthgagwillhelppassastomachtubeinanadultcow.
Best practiceBest practice
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Disease prevention and biosecurity
Livestockmovementsareoneofthebiggestfactorsinthespreadofinfectiousdisease.Alwaysknowthehealthstatusofanimalsbeingboughtandmovedandensureadequatequarantineperiodsapply.
Biosecurityreduces/preventstheintroductionofnewdiseasesontoafarmfromoutsidesourcesandisthefirstlineofdefence.
Biocontainmentmeasuresaimtolimitthespreadofdiseasewithinaherdifbiosecurityhasbeenbreachedandanewdiseasehasbeeninadvertentlyintroducedontotheproperty.Disease spreadInfectiousdiseasescanbeintroducedby:
• Diseasedanimals
• Animalsincubatingdisease
• Apparentlyhealthyanimalsthathaverecovered fromdiseasebutarenowcarriers
• Vehicles,equipment,clothingandfootwearof peoplesuchasvets,contractors,otherfarmers, salesmenetc,whomovebetweenherds
• Feedstuffs,especiallyfeedstuffswhichcouldbe contaminatedwithfaeces
• Contaminatedwaterfromsurfacewater, streamsandriversetc
• Manurehandling,especiallybyoutside contractors
• Otherspeciessuchasdogs,cats,wildlife, rodents,birdsandinsects
Biosecurity principles
Biosecuritycontrolhasfourmajorcomponents:
• Selection
• Isolation
• Movementcontrol
• Sanitation
Selection
Selectallnecessarypurchasedanimalsfromknownsourceswhichhaveahealthstatusequalto,orhigherthantheexistingherd.
• Knowthehealthhistoryoftheherdsfromwhich cattlearepurchased
• Knowthehealthstatusofanimalsbroughtonto thefarm
• Neverbringinanimalswithoutknowingtheir vaccinationhistory
• Limitpurchasestomaidenheifersandbulls
Isolation
Strictisolationpreventscontactbetweenanimalsafterarrivalonfarmtoreducetheriskofspreadofinfectiousagents.
• Quarantineallnewarrivalsforatleast30days
• Cattlemustnotsharecommunity pastures/commongrazings
• Cattlemustnotsharefencelineswitha neighbour’scattle
• Donotusehirebullsfromotherfarms.
Movement control
Thisincludesallvehicle,animalsandpeopletrafficthatcouldintroduceinfectionontothefarm.
• Recordallvisitorstothefarmbothhumanand domesticanimals
Best practice continued
36 37
Keepcattleseparatebetweenneighbouringfarmswithadequatefencing.
Sanitation
Thisaddressesthedisinfectionofmaterials,peopleandequipmententeringthefarmandthecleanlinessofthepeopleandequipmentonfarm.
• Preventmanurecontaminationoffeedand feedingequipment
• Usedifferentequipmenttofeedandmuckout pensordisinfectbetweenuse
• Neverstepinthefeedbunker
• Transportanimalsincleanvehiclesonly
• Sitethelorryloadingareaattheperimeterof thefarm
Other steps to maintain biosecurity
• Maintainaclosedherdwhereverpossibleusing artificialinseminationtointroducenewgenetics. Oestrussynchronisationprogrammescanbe verysuccessfulingroupsofbeefcattle especiallyheifers
• Controldiseasesbyvaccination
• Maintainperimeterfences
• Donotimpulsebuyanimalsfromunknown sourcesatmarketordispersalsales.Theymay bringnewanddevastatingdiseaseontothefarm
Discuss the herd health plan, disease surveillance programme and disease response actions with the vet on a regular basis.
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Diseasecanbespreadbymanurebroughtinfromotherfarms.Donotunloadmuckwherecattlewillgraze.
Best practice
Top herd health tips 1. Maintainbiosecurity–donotbuyindisease.
2. Monitorherdhealthstatus.Checkwhatdiseasesarepresentbybloodsamplingyoungstock.
3. Cullinfectedanimalseg,animalspersistentlyinfectedwithBVDorcarryingIBRorJohne’sdisease.
4. Controldiseasesthatcannotbeeradicated.Vaccinationpoliciessavemanytimestheircost.
5. Implementeffectivetreatmentprotocolswherediseasecannotbecompletelyprevented.Limitdamagebytreatingthediseaseasquicklyandeffectivelyaspossible.
6. Improvemanagementpracticeseg,batchcalving,allin/alloutpolicies.
7. Improvetheenvironmenteg,improveventilationinstockbuildings.
8. Recordreproductiveperformance.Beefproductionstartswiththebirthoflivecalves.
9. Recordgrowthrates.Findoutiftheanimalsarerespondingtotheirfeedinput.
10. Takeateamapproachtoreducingdiseaseandthecostsassociatedwithpreventing,managingandtreatingit.Involvestockmen,vetsandotheradvisors.
For more information contact:Better Returns ProgrammeAHDBBeef&LambStoneleighParkKenilworthWarwickshireCV82TL
Tel: 024 7647 8834Email: [email protected]
AHDB Beef & Lamb is a division of the Agriculture and Horticulture Development Board (AHDB)
© Agriculture and Horticulture Development Board 2015 All rights reserved.