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1. Basic Human Pathology Lecture #5 Acute Inflammation / Wound ... 2. Overview: Tissue Responses to Damage Tufts OpenCourseWare © 2008 Tufts University Acute Inflammation/Wound Healing and Repair I OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1
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Page 1: Basic Human Pathology - Lecture 5

1. Basic Human Pathology Lecture #5 Acute Inflammation / Wound ...

2. Overview: Tissue Responses to Damage

Tufts OpenCourseWare © 2008 Tufts University

Acute Inflammation/Wound Healing and Repair I

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1

Page 2: Basic Human Pathology - Lecture 5

3. Acute Inflammatory Response

4. Acute Inflammatory Response

Tufts OpenCourseWare © 2008 Tufts University

Acute Inflammation/Wound Healing and Repair I

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 2

Page 3: Basic Human Pathology - Lecture 5

5. Acute Inflammatory Response

6. Acute Inflammatory Response

Tufts OpenCourseWare © 2008 Tufts University

Acute Inflammation/Wound Healing and Repair I

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 3

Page 4: Basic Human Pathology - Lecture 5

7. Formation of Acute Inflammatory Exudate

8. Formation of an Acute Inflammatory Exudate

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Acute Inflammation/Wound Healing and Repair I

OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 4

Page 5: Basic Human Pathology - Lecture 5

9. Clinical Effects of Acute Inflammation

10. “4 + 1” Cardinal Signs of Inflammation

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Acute Inflammation/Wound Healing and Repair I

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Page 6: Basic Human Pathology - Lecture 5

11. Acute Inflammatory Response

12. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 7: Basic Human Pathology - Lecture 5

13. Acute Inflammatory Response

14. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 8: Basic Human Pathology - Lecture 5

15. Acute Inflammatory Response

16. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 9: Basic Human Pathology - Lecture 5

17. Acute Inflammatory Response

18. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 10: Basic Human Pathology - Lecture 5

19. Acute Inflammatory Response

20. Key Facts - Neutrophils

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Acute Inflammation/Wound Healing and Repair I

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Page 11: Basic Human Pathology - Lecture 5

21. Acute Inflammatory Response

22. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 12: Basic Human Pathology - Lecture 5

23. Acute Inflammatory Response

24. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 13: Basic Human Pathology - Lecture 5

25. Acute Inflammatory Response

26. Neutrophil Granules and Their Contents

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Acute Inflammation/Wound Healing and Repair I

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Page 14: Basic Human Pathology - Lecture 5

27. Acute Inflammatory Response

28. Neutrophilic phagocytosis - cont’d

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Acute Inflammation/Wound Healing and Repair I

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Page 15: Basic Human Pathology - Lecture 5

29. Acute Inflammatory Response

30. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 16: Basic Human Pathology - Lecture 5

31. Acute Inflammatory Response

32. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 17: Basic Human Pathology - Lecture 5

33. White Blood Cells (a.k.a. leukocytes or WBC’s)

34. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 18: Basic Human Pathology - Lecture 5

35. Parulis (gum boil; abscess on the gingiva) = localized accum...

36. Pus draining from a fistula of an abscessed tooth

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Acute Inflammation/Wound Healing and Repair I

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Page 19: Basic Human Pathology - Lecture 5

37. Fibrinous Exudate – Pericardium

38. Purulent Exudate of the Brain

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Acute Inflammation/Wound Healing and Repair I

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Page 20: Basic Human Pathology - Lecture 5

39. Abscess in the Skin = Localized Accumulation of Neutrophils...

40. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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41. Acute Inflammatory Response

42. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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43. Acute Inflammatory Response

44. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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Page 23: Basic Human Pathology - Lecture 5

45. Acute Inflammatory Response

46. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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47. Cell Membrane Phospholipids

48. Endogenous Mediators:

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Acute Inflammation/Wound Healing and Repair I

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Page 25: Basic Human Pathology - Lecture 5

49. Acute Inflammatory Response

50. Biosynthesis of Leukotrienes and Lipoxins

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51. Acute Inflammation Mechanisms

52. Acute Inflammation Mechanisms

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53. Acute Inflammation Mechanisms

54. Acute Inflammation Mechanisms

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55. Acute Inflammation Mechanisms

56. Acute Inflammation Mechanisms

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57. Acute Inflammation Mechanisms

58. Acute Inflammation Mechanisms

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59. Acute Inflammation Mechanisms

60. Acute Inflammation Mechanisms

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61. Acute Inflammation Mechanisms

62. Acute Inflammation Mechanisms

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63. Acute Inflammation Mechanisms

64. Acute Inflammation Mechanisms

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65. Acute Inflammation Mechanisms

66. Acute Inflammation Mechanisms

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67. Overview of the Complement System

68. Acute Inflammation Mechanisms

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69. Acute Inflammation Mechanisms

70. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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71. Acute Inflammatory Response

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Acute Inflammation/Wound Healing and Repair I

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