Basic Cardiopulmonary Interactions Melvin C. Almodovar MD Divisions of Pediatric Cardiology and Pediatric Critical Care Children’s Heart Center University of Miami Miller School of Medicine/Holtz Children’s Hospital PCICS Preconference: Simulation and Cardiopulmonary Interactions, December 13, 2018
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Basic Cardiopulmonary InteractionsBasic Cardiopulmonary Interactions • O 2 uptake and CO 2 elimination in the lungs • Determined by: –Alveolar ventilation (minute ventilation
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Basic Cardiopulmonary Interactions
Melvin C. Almodovar MD
Divisions of Pediatric Cardiology and Pediatric Critical Care
Children’s Heart Center
University of Miami Miller School of Medicine/Holtz Children’s Hospital
PCICS Preconference: Simulation and Cardiopulmonary Interactions, December 13, 2018
No Disclosures
Cardiopulmonary interactions
Overview of heart-lung interactions
• Individual structural & dynamic properties
• Anatomically & physiologically interconnected
• Occupy the same physical space, therefore mechanical interactions
• Interactions are amplified in disease
Basic Cardiopulmonary Interactions
The ubiquitous & pervasive nature of heart-lung interactions
Basic Cardiopulmonary Interactions
Fetal life, postnatal transition
Normal, healthy activity
Critical Ilness
Cardiopulmonary Interactions
Outline of Talk #1
• Review basic principles of respiratory function
• Review basic principles of cardiac function
• Discuss the effects of respiration on CV function under normal circumstances
– Spontaneous breathing
– Positive pressure ventilation
Reference literature on CP interactions
Cardiopulmonary interactions in healthy children and children after simple cardiac
surgery: the effects of positive and negative pressure ventilation.
Shekerdemian LS, Bush A, Lincoln C, Shore DF, Petros AJ, Redington AN.
Heart. 1997 Dec;78(6):587-93.
Cardiovascular effects of mechanical ventilation.
Shekerdemian L, Bohn D.
Arch Dis Child. 1999 May;80(5):475-80
Cardiopulmonary Interactions.
Bronicki RA, Penny DJ, Anas NG, Fuhrman B.
Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S182-93.
Cardiopulmonary Interactions in Children with Heart Failure.
Bronicki RA.
Curr Cardiol Rev. 2016;12(2):104-6
Heart-lung interactions during mechanical ventilation: the basics.