Bacteriophage Project @Hackuarium

Bacteriophage Project@Hackuarium

By Jonathan Sobel

3D modeling

• Small molecules• Protein• Virus• Other biological structures (root of Arabidopsis)

3D Printing Technology

Plastic laser-sintering system

Fused deposition modeling

• Educational purpose• Ergonomic• Buildable• Low-cost• Open Source

Bacteriophage Project

• In house competence for 3D model development

• Phage model available• Development of a bacterial model • Model usable for educational purpose • Phage therapy represents an alternative to

antibiotics (especially for multi-resistant bacteria)

• Phages are extensively used in research (antibody engineering)

Conclusions

Bacteriophage Biology

Phage T7 genome 40Kbp dsDNA55 proteins encoded

Bacteriophage Biology

Phage Display

Antibody engineering

Phage Therapy

3D Printing Working Group

• Hackuarium: Guy, Jonathan S., Anne-Laure, Marco

• Fab Lab Chêne 20: Richard, Jonathan F., Olivier• L’Eprouvette: Severine, Mathilde• Musée de la main: Roxanne • STI EPFL: Roland