Our funders: Automation of Genetic Design National Academy of Sciences Industrialization of Biology Workshop February 17, 2014 J. Christopher Anderson Assistant Professor, Bioengineering 512E EBB, UC Berkeley [email protected]http://andersonlab.qb3.berkeley.edu
15
Embed
Automation of Genetic Design - DELS Microsite Networknas-sites.org/synbioroadmap/files/2014/04/3.-Anderson-Chris.pdf · This tutorial will guide you through the basics of genetic
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Exhaustively compute the biosynthetically reachable space Enumerate all paths to each reachable chemical Rank those pathways for plausibility Provide linkage to the DNA sequences (parts) that encode each enzyme
True
The L0-L2 Reachable Space
Filtering the Reachable Space
Filtering the Reachable Space
Validation of an L2 target: Tylenol
Known Prediction Holes
Expression in foreign host Chemical modifications Multiple subunits Kinetic parameters Membrane/organellar localization Spontaneous reactions Volatile products