Autologous serum eye drops in severe post- LASIK dry eye. Alberto Arntz MD, Andrea Cruzat MD, Arturo Grau MD. Pontificia Universidad Católica de Chile The authors have no financial interest in the subject matter of this poster. Autologous serum eye drops are not FDA aproved.
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Autologous serum eye drops in severe post-LASIK dry eye.
Autologous serum eye drops in severe post-LASIK dry eye. Alberto Arntz MD, Andrea Cruzat MD, Arturo Grau MD. Pontificia Universidad Católica de Chile. The authors have no financial interest in the subject matter of this poster. Autologous serum eye drops are not FDA aproved. Purpose. - PowerPoint PPT Presentation
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Autologous serum eye drops in severe post-LASIK dry eye.
Alberto Arntz MD, Andrea Cruzat MD, Arturo Grau MD.Pontificia Universidad Católica de Chile
The authors have no financial interest in the subject matter of this poster.Autologous serum eye drops are not FDA aproved.
Purpose
To evaluate the efficacy and safety of Autologous Serum eye drops for the treatment of severe post-LASIK dry eye syndrome.
MethodsInclusion Criteria
• Patients with no previous dry eye history, who underwent uneventful LASIK and presented severe dry eye signs 4 weeks after surgery in spite of conventional unpreserved artificial tears therapy.
• Severe dry eye diagnosis was stablished when the patient met all three criteria:– 2 lines lost of best-spectacle corrected visual acuity (BSCVA).– Corneal fluorescein staining score (FSC) ≥ 1.– Residual astigmatism ≥ 1.0D
MethodsCorneal Fluorescein Staining Score (FSC)
Diffuse and complete corneal staining4
Confluent inferior 1/2 corneal surface staining3
Confluent inferior 1/3 corneal surface staining2
Isolated punctate staining1
No staining0
MethodsRecruitment and Follow-up
- Recruitment during one year period.- Patients who met inclusion criteria were enrolled after
informed consent.- Autologous serum was obtained and prescribed 6 times a
day for 1 month.- 3 months follow-up with monthly visits.- Parameters evaluated every visit:
Main outcome measures pre and post autologous serum treatment: BSCVA= best spectacle corrected visual acuity in snellen equivalent; Values presented as media ± standard deviation. P = statistical level of significance.
Conclusions• Our study suggests that autologous serum is a safe and
effective alternative that improves visual function and reduces ocular surface damage in severe post-LASIK dry eye unresponsive to conventional non-preserved artificial tears.
• A slight regression in the corneal epithelial fluorescein staining score after AS withdrawal suggests that treatment time should be longer than four weeks.
• Long prospective doble-blind studies are needed to confirm our study results.