Slide 1
Why animals need a large surface area to volume area:oxygen must
be supplied for respirationheat generated by metabolism must be
lostwaste i.e. CO2 and urea needs to be removedcells need to be
supplied with nutrients i.e. Glucose, amino acids and mineral
ionsFeatures of specialised exchange surfaces:large surface area to
volume ratio speeds up the rate of exchangevery thin barrier allows
materials to cross quickly reduce diffusion timePartially permeable
to allow selected materials to crossMovement of the environmental
medium e.g. Air to maintain a diffusion gradientmovement of the
internal medium e.g. blood to maintain a diffusion gradient
Biology: mrs searles 1revision cardsTobi Ojo12.3Large organisms
are multicellular: many cells so a greater surface areaLarge
organisms develop specialised exchange surfacesThe bigger the ratio
of surface area to volume the faster the rate of diffusionAmoeba:
simple diffusion across outer surface since it has a large
sa:vInsects: simple diffusion through spiracles in its exoskeleton.
Sa:v gets smallHuman beings: sa:v is very small. The outer surface
isn't big enough to allow enough gases to enter the body.Large
organisms develop mass flow transport systems Respiration- when
CO2, energy and H2O is made. If it's aerobic it takes place in
mitochondria. Forms energy in the form of
ATP.Glucose+oxygen>CO2+H2O+energy
Trachea- supported tube that connects the lungs to the
outsideRib cage- protects the lungs in a bony boxIntercostal
muscles- muscles that move the ribsAlveoli- air sacsBronchi- two
smaller tubes that the trachea divides intoBronchioles- smaller
tubes going to the alveoli Larger organisms need a larger area to
exchange more substances. Often this is combined with a transport
system to move substances around the body. Surface areas
are adapted to make it easier for molecules to cots from one
side to another.
Examples of specialised exchange surfaces:walls of alveoli in
the lungssmall intestines nutrients absorbedliver levels of sugar
adjustedroot hairs of plants minerals absorbedhyphae of fungi
Inhalation (inspiration):Diaphragm contracts to become flatter
and pushes digestive organs downExternal intercostal muscles
contract to raise ribsVolume of chest cavity increasesPressure in
cavity drops below atmospheric pressure then air moves into the
lungs Exhalation (exportation):diaphragm relaxes and is pushed up
by displaced organs underneathInternal intercostal muscles relax
and ribs fallVolume of chest cavity decreasesPressure in cavity
increases and raises above atmospheric pressure air moves out of
lungsThorax- chest cavityThe lungs:The trachea, bronchi and
bronchioles are airways that allow air in and out of the lungs.
They must: Large enough to allow enough air slowDivide into smaller
airways to reach the alveoliStrong enough so they don't collapse
Flexible to allow movementAbel to recoil as pressure is
changingTrachea and bronchi:Have similar structures. Both have
thick walls bronchi is narrower. Walls mostly cartilageCartilage
forms c-ring in trachea less I bronchiCartilage- glandular tissue,
connective tissue, elastic fibres, smooth muscle, blood
vesselsContains ciliates epithelium and goblet cells secrete
mucusRoles of tissue:Cartilage- structural role supports the
trachea and bronchi holding them open.Smooth muscle- can constrict
thus controlling the flow of air in/out of the alveoli.
Smooth muscle- Useful if there are harmful substances in the
air.Elastic fibres- as the smooth muscle relaxes the elastic fibres
coils to their original size and shape. Dilates the airways.Goblet
cells & glandular tissue- secretes and traps mucus.Ciliated
epithelium- hair like structures called cilia which wafts mucus up
the airway into the throat. Adaption of alveoli:large surface
areaextremely thinlined with squamous epitheliumkept moist by fluid
from epithelial cells- helps diffusion
Atrial systole- valves are fully open, atrium is contracting
blood flows into left ventricle, semilunar valves still closed.
Ventricle systole- av valves are closed, semilunar valves are
open, ventricles are contacting
Valves prevent back flowCardiac muscle:Contracts without fatigue
Appears a striped under microscopeContains actin & myosin
proteinsLots of mitochondria Cavity of alveolus:Low co2
concentration, high O2 concentrationEndothelial cell of
capillary:High co2 concentration, low O2 concentration inside red
blood cells
Spirometers:wear a nose clip- so they don't breathe through nose
and make results invalidair right seal around mouth piecedisinfect
mount piecefresh air in chamberVolume in spirometer drops in first
minute because oxygen I'd being used by respiration and co2 being
breathed out is absorbed by the sodalime. So overall volume goes
down.Inspiration reserve volume- Is how much air can be breathed in
I've and above normal tidal wave volume when you take in a big
breathInspiratory reserve volume- is how much more air can be
breathed out over and above the amount that is breathed in a tidal
volume breath.A person breathes onto the mouthpiece and the volume
of air in the air chamber changes. The movement caused by this
change is recorded by the recording pen. Tidal volume- is the
volume of air when a person is breathing quietly.Vital capacity- is
the maximum volume of air exchanged from full expiration to full
inspiration.Residual volume- is the volume of air that always
remains in the lungs even after the biggest possible exhalationDead
Slavs if the air in the bronchioles, bronchi and trachea.
Histamine:A drug for allergy. Stops the symptoms of an allergic
reaction. Histamine is released by cells as part of an allergic
reaction. Histamine binds to the receptors on the membrane of
target cell as it has a complimentary shape. This triggers a
response inside of the cell it also increases permeability of
capillary. Histamine suppresses body's natural responses. Single
circulatory systems:1 path to the heart, 1 circuit, closed system
(blood travels in blood vessels) Blood pressure reduced Does not
flow quicklyLimits rate at which oxygen and nutrients
deliveredDouble circulatory systems: 2 paths to the heart, 2
circuits, lungs, closed system, blood flows through the heat twice
in a single cycle. Humans have a higher demand for oxygen.Heart can
increase blood pressureOpen circulatory system- blood not always in
vesselsClosed circulatory system- blood always remains in
vessels
Factors that affect the need for transport system:Size, sa:v
ratio, how active organism is Structure of heart:covered by tough
membrane- pericardiumencloses the pericardial fluidneeded to
lubricate the movement of heart in pericardiumleft- oxygenated
blood, right- deoxygenated bloodStructure of cardiac
muscle;epicardium is outer layer of the heart wallendocardium is
inner layermade if epithelial cells and connective tissuemyocardium
is middle layer
Atrium is thin walled and elastic pumps blood a short distance
to the ventricle, small amount of muscleVentricle is thicker
muscular walls pumps blood further to lungs or bodyDiastole- the
ventricle are relaxed, the av valves aren't fully open, semilunar
valves are closed
Heart is myogenic- initiate its own contractionAtria and
ventricles have own natural frequency of contractionAtrial muscles
contract at higher frequency than ventricles. Inefficient pumping
Red blood cells- transports oxygen around the bodyCapillaries- acts
as a passage where oxygen and nutrient in blood are delivered to
tissue.Sino atrial node(SAN) generates electrical activity. Wave of
excitation spreads through walls of both atria causes muscles to
contract. - atrial systole
Atrioventricular node (AVN) wave of excitation goes down purkyne
tissue. At base of septum(apex) excitation spreads out across
ventricles causing contraction.ECG- electrocardiogramUsed to
measure electrical activity in heart. Electrical activity in the
heart spread through other surrounding tissues and can be picked up
using sensors on the skin.
(fibrillation) could be caused if all 4 chambers are not
synchronised.The SA node is a patch of tissue located in the heart
which generates electrical activity. The wave of excitation causes
the atria to contract. The excitation in the av node is delayed so
the atria can fully contract. Afterwards the wave of excitation
passes down the septum/apex and spreads up the walls of the
ventricle resulting in the ventricles contracting.
Arehythmias:A change in the rhythm of your heartbeat. When the
beady beats too fast, it's called tachycardia. When it beats too
slow, it's called bradycardia. Beats can be irregular.Atrial
fibrillation:This causes the ventricles to contract faster than
normal. When this happens the ventricles don't have enough time to
fill completely with blood to pump to the lungs and body.Artery and
related function:thick walk- stops bursting/withstands
pressurenarrow lumen- to maintain pressureelastic tissue- allows
stretchingelastic recoil- it can maintain its shape under high
pressurecollagen- structure and supportsmooth muscle- maintain
pressuresmooth endothelium- reduce friction, allows blood to flow
easilyArtery, aorta, arteries, arterioles, capillariesVein:Similar
to arteries but transport blood at a lower pressure so they aren't
as strong.They have three layers, each layer is
thinner.Capillaries:Smallest blood vessels they distribute
oxygenated blood from the arteries out to tissue of your body then
move deoxygenated blood from tissues back to veins.Tissue
fluid:Colourless fluid (no red blood cells) that is formed from
blood plasma by pressure filtration through capillary walls
(forcing the liquid out needs to get buried a to cell)Only small
molecules get filteredSurround all the cells of the body and all
exchanges between blood and cells occur through it.Blood cells: red
blood cells (erythrocytes), white blood cells (leucocytes),
platelets (cell fragments) help blood clot.Plasma- fluid that
carries around all the water, glucose, amino acids, urea and some
of the co2Blood - carries materials around the body: plasma 55%,
blood cells 45%Phagocytes/ neutrophil-Engulf bacteria by
phagocytosis.Lymphocyte- the release of antibodies.Human Lymphatic
system:System of thin tubes that run throughout body called lymph
vessels. Lymphatic systems jobs: drains fluid into bloodstream from
tissue, filters lymph, filters blood, fights infections
Lymph flows through lymphatic vessels passes through lymph nodes
where it gains white blood cells and antibodies. Excess fluid
returns to blood ensures that tissue do not fill with too much.
Tissue fluid build up is a result of a blockage. This occurs when
the fluid can't get to the lymph and be drained.Partial pressure of
oxygen- the concentration of oxygen available.Percentage
saturation- represents the amount of oxygen being carried by
oxyhemoglobin i.e. Low saturation haemoglobin has been used in
other cells.Picks up ions. Shape changes after 1st molecule because
picking up oxygen making it easier to pick up more. Oxygen uptake:
Oxygen diffuses into blood plasma in the lungs. It enters the red
blood cells. Then it is taken up by haemoglobin which takes it out
of solution thereby maintains concentration gradient allowing
further oxygen to enter the cell. 1. At low pO2 it is hard for
oxygen molecules to attach2. As pO2 rises and some oxygen molecules
attach to haemoglobin it becomes easier to attach. Explains shape
of curve.3. As it becomes saturated it becomes more difficult for
oxygen to attach to haemoglobin.Foetal haemoglobin has more
Myoglobin found in muscles. The speciation curve well to left of
haemoglobin. It is an oxygen store which enables the muscle to
continue contracting. It only releases oxygen at a vet low partial
pressure of oxygen.Bohr shift:This is whenCO2 level increases
(pCOs) the haemoglobin dissociation curve shifts to the
right.Haemoglobin is more efficient at releasing oxygen since
tissue becomes more active and the rate of respiration increase.
Tissue receives more oxygen . When CO2 decreases oxygen is picked
up by haemoglobin more efficiently. CO2 transport:blood carries CO2
partly in plasmacombined with haemoglobin in rbcs forming
carbaminohaemoglobinpartly as hydgencarbonate HCO3 ions
oxygen than normal haemoglobin (have high affinity for oxygen)
in order to survive and receive oxygen from the placenta. After
baby is born haemoglobin goes to normal. If women and baby both
have foetal haemoglobin the baby wouldn't get enough oxygen.
Dissociation curve is to the left if maternal.
Haemoglobin: globular protein. Contains 4 polypeptide chains.
Contains 4 harm groups for binging O2. Hydrostatic pressure is
generated in the heart by the ventricle muscles contracting.
Hydrostatic pressure drops as blood moves away from the heart
because the surface area of the capillaries are much larger than
the arteries since there are more and smaller vessels. This means
the pressure is spread and less.Training at Altitude:Long-distance
races are dominated by African athletes who spend most of their
lives at altitude and whose bodies get used to making the most of
the oxygen. When the body has to make a limited supply of oxygen it
produces more rbcs. Oxygen is delivered to muscles.Haemoglobin
consists 4 subunits (haem group- Fe2+ & polytides) The haem
group can hold oxygen it attracts it. If theres a low partial
pressure/oxygen tension (pO2) it hard to associate with O2 (1st
molecule) but after the molecule it causes a slight change in the
shape of haemoglobin which makes it easier to attract 2 more O2.
when it comes to the 4th subunit its hard to reach 100%How is CO2
transported?CO2 diffuses into the red blood cells and combines with
water with the help of carbonic anhydrase (enzyme). The product of
this reaction is carbonic acid which dissociates releasing
hydrocarbonate ions out of the blood cell. And CL enter the cell
(maintains charge/CL shift) Haemoglobonic acid is formed.
Additionally oxyhaemoglobin enters cell and dissociates releasing
o2 to blood plasma.Carbon monoxide:Carbon monoxide can combine with
haemoglobin meaning O2 will no longer be able to this is cause
carbon monoxide has a higher affinity. This can cause problems with
the transport of oxygen.The air pressure is lower at high altitudes
than at sea level. This causes shortness of breath. To compensate
more rbcs are made from 45% to 70%. This acclimatisation takes
about a week. People living permanently at altitudes have
adaptations: broader chests, larger lung capacity, larger heart,
more haemoglobin.Functions in plants:Leaves: trapping sunlight and
converting it into energy. Key role in photosynthesis . Controls
the entry of gaseous exchange.Stems: transport system move things
around. Support/structure. Xylem and phloem.Roots: absorb water/
dissolved minerals. Roots anchor plant. Transport in multicellular
plants:Theres two distinct parts: leaves site to photosynthesis,
roots absorb water. They need to be connected this is done by the
vascular bundle which goes through the roots up the stem into the
leaves. Strength/ support.Vascular tissue in stem: Vascular bundles
found at edge of stem. Xylem are found towards the inside. Phloem
towards the outside. Cambium between it.Parenchyma- living tissue
made of thin walled prenchyma cells, the most abundant type of cell
in plant body. Function is to heal and regenerate new cells also
for photosynthesis storage.Collenchyma- tissue for strengthening
plants.Solmenchyma- tissue for strengthening, often described as
fibres and can be long and tapered. Structure: Xylem tissueTubes-
water dissolved minerals carrying tissue in the vascular bundle
these are vessel elements (verticle chain of dead cells) /
tracheids.Fibres- to help support plantLiving parenchyma cells.Has
perforation plates.Cell walls impregnated with lignin.Pits/ no
content.
Structure: PhloemHas sieve tube elements, elongated structures,
cells are living contain small amount of cytoplasm within membrane,
cells have some mitochondria, no nucleus, golgi, ribosomes. Each
have perforated end walls sieve plates.Companion cells carry out
functions which sieve tubes cant cause of lack of
organelles.Materials pass through plasmodesmata, link two
cells.Xylem functions:Narrow lumen increase height, water rises
(capillary action)Long cells arranged continuos columnCell walls
thickened(lignin) dont collapseDead cells no
cytoplasm/nucleusAnnular, spiral thickening allows elongation/
bending.
saturation but it eventually does. When oxygen attached its
called oxyheamoglobin. Cells need oxygen for respiration so when
its need o2 is released from oxyhaemoglobin this is dissociation.
Also to maintain a steep diffusion gradient haemoglobin takes up o2
so more oxygen can diffuse into the blood. Fetal haemoglobin needs
to be higher so it can pick o2 from envirome
Vascular tissue in root: vas tissue distributed throughout
plant. Xylem are phloem found together in vascular bundles. `vas
bundle in the centre, structure gives strength.Vascular tissue in
leaf: form midrib and veins in leaves. Two major groups:
dicotyledons, monocotyledons. Xylem on top of the phloem.
In the arteries the blood plasma moves out of the blood and
forms tissue fluid. The hydrostatic pressure is greater than water
potential. This is why the relative pressure is higher at the
arteries than the veins.Mass flow:Movement of water into phloem.
Pressure forces phloem sap to move toward the sink.Mass flow
carries substances along the phloem it can occur in either
direction but goes down hydrostatic pressure gradient.Source-
builds pressureSink reduces pressureTranslocation:Phloem transport
more sugars and other chemicals made by plant (assimilates).
Transported in live cells ex. Sieve & companion cells. Source:
sugar production site photosynthesis, starch breakdown in storage
area where sucrose is released.Sink: sugars uptake site, growing
areas, storage areas, fruits+seeds where sucrose is removed and
sent to xylem.Phloem structure: nucleus & many organelles in
Ccells allows spaceCellulose walls- strength/ burstingElements
elongated and arranged continuous columnPeforated walls allows
water flowCompanion cells many mitochondria ATP for
translocation.Can flow either wayWater uptake: Epidermis has root
hairs, minerals absorbed by active transport using ATP. Minerals
reduce WP of cytoplasm. WP in cell was lower than soil. Water is
taken up across membrane by osmosis. 3 pathways for water in cells:
apoplast, symplast and vacuolar. Before water gets into the xylem
it travels through the cortex and central structure.Endodermis has
a waterproof strip called casparian strip. This blocks apoplast
pathway forcing water to go through symplast pathway. Endodermis
moves minerals into xylem by active transport. WP in xylem
decreases and water moves in (osmosis). Casparian strip controls
substance by forcing water into cytoplasm, creates water potential
in xylem, stops back flow (via apoplast pathway)Apoplast: water
between cellulose in cell walls. Water moves through spaces. Water
doesnt pass through plasma membrane. Dissolved mineral ions &
salt can be carried.Symplast: water enters cytoplasm through plasma
membrane. Passes between cells through plasmodesmata. Water can
flow through linked cells. 3 explanations to move water up the
stem: root pressureBecause the xylem has a lower water potential
water is pushed up by metres. However its not enough if push water
to the top of a large plant.Capillary action: forces also attract
the water molecules to the side of the xylem adhesion. The
narrowness of xylem means that this can pull water up the
xylem.Transpiration pull: water molecules are attracted to each
other by forces of cohesion. Molecules leave the leaf by
evaporation and the molecules are held together is pulled up like a
chain causing tension. Water evaporates from guard cells so water
moves in from neighbouring cells.Transpiration: the loss of water
by evaporation from the upper parts of the plant. Stomata occurs
mainly in leaves & accounts for 90% water lost.Cuticle waxy
external layer limits water loss account 10%Lenticils loosely
packed cells on surface through water is lost.Factors affecting
transpiration rate:Number of leavesNumber, size, position of
stomataPresence of cuticleLightTemperature: rate of evaporation,
diffusionRelative humidityAir movement + water availabilityPlants
living in dry, arid places have adaptations to reduce water loss.
These are called xerophytes.Adaptations: hairs limit air
movementLeaf rolled reduction in surface area.Thick waxy cuticle
reduces water loss through cuticles.Stomata in pits moist air
trapped close to the area of water loss reducing rate of water
loss. Stamatas' closed during light.Reduced no. stomata reduces no.
of pores through which water loss occurs.Deep root roots tap into
lower water.Phloem loading at source: ATP is used by companion
cells to actively transport H+ ions out of cytoplasm into tissue.
This sets up a diffusion gradient and the H+ ions diffuse back in.
Proteins enable H+ ions to bring sucrose molecules into companion
cells (co transporter proteins). As the sucrose builds it diffuses
into sieve elements through plasmodesmata.Leaf structure:
Phototropism is a growth response which allows shoots to grow
towards light. Large leaf surface area is held perpendicular to the
light source.Leaves are thin so there's few cell layers to absorb
light.Leaf mosaic is arrangement of leaves in a pattern which
minimises overlapping.Shoot system holds leaves in optimum
positionEtiolation causes rapid elongation of internodes.