Arterial blood gas analysis. Recording of respiratory + hemodynamic parameters. 0 NAVA level titration EMG-ENG, baseline pressure support ventilation (PSV) Stop sedation / NVET NVET standardized tests of neuro-ventilatory efficiency Clinical assessment according to the MRC Study enrolment Baseline measurements Follow up for 48 hrs 24 48 12 36 60 NAVAal NAVAal NAVAal NAVA level titration NAVA level titration NAVA level titration 48 hrs 72 hrs 48 hrs 24 bl EMG-ENG, follow up Stop sedation / NVET Stop sedation / NVET Stop sedation / NVET Figure E1