Supplementary data MANUSCRIPT TITLE: Organophosphorus flame retardants and plasticizers: Sources, occurrence, toxicity and human exposure AUTHORS: Gao-Ling Wei, Ding-Qiang Li, Mu-Ning Zhuo, Yi-Shan Liao, Zhen-Yue Xie, Tai-Long Guo, Jun-Jie Li and Zhi-Quan Liang ADDRS: Guangdong Key Laboratory of Agricultural Environment Pollution Integrated Control, Guangdong Institute of Eco-Environmental and Soil Sciences, Guangzhou 510650, 1 1 1 2 3 4 5 6 7 8 9 10 11 2 3
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Supplementary dataMANUSCRIPT TITLE: Organophosphorus flame retardants and plasticizers: Sources,
Zhen-Yue Xie, Tai-Long Guo, Jun-Jie Li and Zhi-Quan Liang
ADDRS: Guangdong Key Laboratory of Agricultural Environment
Pollution Integrated Control, Guangdong Institute of Eco-
Environmental and Soil Sciences, Guangzhou 510650, China,
Guangzhou Branch, Chinese Academy of Sciences,
Guangzhou 510075, China and University of Chinese
Academy of Sciences, Beijing 100049, China
NO. OF TABLES: 13
NO. OF PAGES: 55
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Human exposure via dust ingestion
In order to make a preliminary evaluation of the human exposure to organophosphorus
(OPs) flame retardants and plasticizers via dust ingestion, we assume 100% absorption of
intake. Average dust ingestion rates are estimated at 20 and 50 mg/d for adults and toddlers,
respectively, while the corresponding high rates become 50 and 200 mg/d (Jones-Otazo et al.,
2005). The values of body weight (bw) are 70 (or 60 or 50) kg for adults and 12 (or 12.3 or
15) kg for toddlers, respectively. Dust ingestion is assumed to be pro-rata to the time spent in
a microenvironment category (Harrad et al., 2008), thus it is necessary to consider different
time-activity patterns for adults and toddlers in different types of microenvironments. Daily
intake of OPs via dust ingestion is estimated with the following equation (Ali et al., 2013;
Kim et al., 2013):
ΣExposure (ng/kg bw/d) = Σ[(CiFi)*Ir]/Body weight
where Ir is the dust ingestion rate (mg/d), Ci is the concentrations (μg/g) of OPs in dusts from
the microenvironment i, Fi is the percentage of daily time spent in the microenvironment i.
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Table S1Comparison of the concentrations (range; arithmetic mean/median; μg/g) of the total of organophosphates (ΣOP) and the predominant halogenated OPs in dusts from various indoor environments worldwide.
Location (no.)
Description of matrix
ΣOP TCEP TCIPP TDCPP Ref
Various indoor environments
Germany (983/436) a
Home, school and business building
–<0.10-121 2.37/0.61
<0.10-375 1.65/0.52
–(Ingerowski et al.,
2001)
Sweden (15)
Domestic, public, occupational site
22.0-5,500 466/59.0
0.19-94.0 11.3/1.40
0.47-73.0 11.0/2.40
0.20-67.0 9.54/1.10
(Marklund et al., 2003)
USA b
(110)Various indoor environments
– – –<0.03-326
4.43/–(Carignan et al.,
2013)HomeSweden(2)
PVC floor22.0-28.0
25.0/–0.19-0.23
0.23/–0.47-0.93
0.70/–0.39-1.10
0.75/–(Marklund et al.,
2003)Sweden(10)
Private home, floor7.00-79.0 36.9/38.0
nd-33.0 7.60/2.10
0.70-11.0 3.10/1.60
2.20-27.0 12.0/30.0
(Bergh et al., 2011)
Germany(6)
Home, floor0.80-6.00
3.00/–0.14-0.28
0.20/–0.37-0.96
0.74/–<0.08-0.11
<0.08/–(Brommer et al.,
2012)Spain(8)
Home, floor3.91-34.8 18.9/21.5
0.25-9.80 1.74/0.51
0.35-10.3 3.91/3.80
nq-1.10 0.38/0.23
(García et al., 2007)
Spain(5)
Home, floor –0.50-11.0
–/3.103.60-8.50
–/3.600.69-2.10
–/0.85(Cristale and Lacorte,
2013)Belgium(33)
Home, floor1.92-94.7 19.4/13.1
<0.08-2.65 0.49/0.23
0.19-73.7 4.82/1.38
<0.08-6.64 0.57/0.36
(Van de Eede et al., 2011)
Romania Home, floor up to 29.0 <0.02-1.16 <0.02-16.4 <0.02-0.46 (Dirtu et al., 2012)
Furniture (w/w) – – 0.5-2.2% 1-5%(Stapleton et al.,
2009)a A total of 983 and 436 samples were analyzed for TCEP and TCIPP, respectively.b Geometric mean value.c Stores including an electronics store, a mattress shop, a pharmacy, a furniture store, a second-hand shop, and a carpenter workshop.d Public places including four coffee shops, four restaurants and three supermarkets.The full names for the halogenated OPs are displayed in Table 1. –: data not available. nd: not detected. nq: not quantified.
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Table S2
Comparison of the concentrations (range; arithmetic mean/median; μg/g) of the predominant non-halogenated OPs among indoor dusts from various microenvironments worldwide.
Location (no.) a TEP TPP TNBP TIBP TMPP TPHP TBOEP TEHP EHDPP Ref
Various indoor environmentsSweden (15)
– –0.07-2.20 0.53/0.35
– –0.85-110 11.4/3.10
14.0-5,300 419/31.0
0.06-13.0 1.03/0.16
–(Marklund et al.,
2003)HomeSweden(2)
– –0.21-0.61
0.41/–– –
0.85-0.99 0.92/–
18.0-25.0 21.5/–
0.06-0.070.07/–
–(Marklund et al.,
2003)Sweden(10)
nd –nd-1.70
0.60/0.300.40-3.60 1.40/1.10
0.10-4.20 1.60/1.20
–0.60-30.0 8.50/4.00
nd-2.20 –(Bergh et al.,
2011)Germany(6)
– –<0.03-0.25
0.13/––
<0.04-0.24 0.09/–
0.18-1.30 0.38/–
<0.06-2.80 0.73/–
– –(Brommer et al.,
2012)Spain(8)
– –0.07-0.65 0.25/0.23
nq-0.27 0.21/0.22
–0.29-9.50 2.60/1.85
1.18-18.5 9.88/9.35
– –(García et al.,
2007)Spain(5)
– –0.05-0.08
–/0.070.09-0.22
–/0.100.35-0.71
–/0.490.80-4.70
–/1.10nd
0.30-0.86 –/0.69
–(Cristale and
Lacorte, 2013)Belgium(33)
<0.05 –0.03-2.70 0.25/0.13
0.70-15.6 4.20/2.99
<0.04-5.07 0.44/0.24
0.04-29.8 2.02/0.50
<0.36-67.6 6.58/2.03
– –(Van de Eede et
al., 2011)Romania(47)
<0.01-0.42 0.03/0.02
–<0.02-0.38 0.07/0.05
<0.10-2.39 0.40/0.39
<0.05-5.50 1.00/0.50
<0.02-22.6 1.60/0.50
<0.05-21.0 2.70/1.50
– –(Dirtu et al.,
2012)
New Zealand
– – –/0.08 – –/0.12 –/0.60 –/4.02 – – (Ali et al., 2012)
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18
36
37
38
19
(34)New Zealand(16)
– – –/0.07 – –/0.16 –/0.24 –/1.55 – – (Ali et al., 2012)
USA(50)
– – – – –<0.15-1,800
7.36/–– – –
(Stapleton et al., 2009)
USA(16)
<0.02-0.41–/0.03
–<0.08-1.80
–/0.03<0.08-0.18
–/0.080.33-4.40
–/1.00–
2.30-68.0 –/12.0
<0.20-3.70–/<0.20
0.18-3.00 –/0.61
(Dodson et al., 2012)
USA(16)
<0.02-0.25 –<0.08-1.80
–/<0.08<0.08-0.12
–/<0.080.18-10.0
–/0.68–
0.79-170 –/11.0
<0.20-0.34–/<0.20
0.14-1.50 –/0.56
(Dodson et al., 2012)
Japan(148)
<0.52-2.80 <0.49-1.13<0.73-133
–/1.03– <4.00-59.8
1.60-245 –/4.51
6.24-5,890 –/508
<1.34-51.0 –/2.07
–(Araki et al.,
2014)Japan(120)
<0.52-3.31 <0.49<0.73-42.8
–/1.15– <4.00-193
<1.60-889 –/11.5
5.29-14,100 –/111
<1.34-73.1 –/1.47
–(Araki et al.,
2014)Japan(41)
<0.52-2.10 –<0.73-15.6
–/1.40– <4.00-13.9
<1.60-78.4 –/5.40
61.8-5,890 –/1,570
<1.34-16.2 –/4.30
–(Kanazawa et al.,
2010)Japan(41)
<0.73-2.10 –<0.73-2.7
–/1.10– <4.00-102
<1.60-175 –/14.3
5.90-749 –/164
<1.34-6.6 –/2.10
–(Kanazawa et al.,
2010)Japan b
(50)– – – – –
<0.17-1,800 7.40/5.47
– – –(Meeker and
Stapleton, 2009)Philippines(17)
– –<0.006-0.08
0.02/0.02–
<0.003-0.25 0.04/0.02
0.008-2.10 0.35/0.09
–0.004-0.970.21/0.14
0.008-0.77 0.18/0.11
(Kim et al., 2013)
Philippines(20)
– –<0.006-0.28
0.04/0.02–
<0.003-0.14 0.03/0.009
0.01-0.44 0.13/0.07
–0.004-0.37 0.07/0.04
0.008-0.56 0.09/0.03
(Kim et al., 2013)
Pakistan(31)
– –<0.02-0.08 0.02/0.01
<0.40-2.18 0.71/0.68
–<0.002-0.63
0.11/0.09<0.02-2.85 0.05/0.03
– – (Ali et al., 2011)
Pakistan <0.005- <0.005-0.12 <0.02-0.02 <0.02-0.04 – <0.002-0.33 <0.02-0.15 <0.005-0.05 <0.002-0.36 (Ali et al., 2013)
a The arrangement and detailed descriptions of the matrices are in accordance with Table S1 without specification.b Geometric mean value.
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c Concentrations in ng/m2 for the dust samples collected from computer screens d Concentrations in ng/m2/h for the dust samples collected from the covers of computer (no. 7) and TV set (no. 8).e Concentrations in w/w for the dust samples collected from computer video display units.The full names for the non-halogenated OPs are summarized in Table 1. –: data not available. nd: not detected. nq: not quantified.
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Table S3
Comparison of the concentrations (range; arithmetic mean/median; ng/m3) of ΣOP and the predominant halogenated OPs in indoor air from various indoor environments around the world.
Location (no.)
Description of matrix ΣOP TCEP TCIPP TDCPP Ref
Various indoor environments
Sweden(30)
Private homes, workplaces, stores, health care facilities and transportation
9.00-2,320 378/102
1.00-870 75.8/11.5
1.00-2,300 273/31.0
–(Staaf and Östman,
2005)
Sweden(17)
Domestic, public and occupational environments
36.0-950 293/160
0.40-730 129/8.90
10.0-570 118/69.0
<0.20-150 36.1/6.00
(Marklund et al., 2005a)
Home
USA(16)
Multistorey apartments –<2.00-8.30 4.40/3.30
3.40-172 26.0/8.30
nd (Bergh et al., 2010)
Germany(50)
Home –up to 6,000
52.0/–– –
(Ingerowski et al., 2001)
Sweden(1)
Living room 230 0.40 210 <0.50(Marklund et al.,
2005a)Sweden(1)
Bedroom 160 3.00 38.0 <0.50(Marklund et al.,
2005a)
Sweden(10)
Apartment and private house, ordinary household equipment
22.0-190 89.0/78.0
1.00-115 16.6/4.00
7.00-160 36.9/27.0
–(Staaf and Östman,
2005)
Sweden(10)
Private home25.0-149 70.0/58.5
nd-28.0 8.30/4.80
2.40-64.0 15.0/5.60
nd-17.0 3.00/–
(Bergh et al., 2011)
15
30
45
46
47
31
Japan a
(25)Summer, tatami mat, carpet, wood and tile floor
–4.96-62.9
20.0/–– – (Takeshi et al., 2006)
Japan a
(21)Winter, wood, tile, tatami mat and carpet floor
–3.85-23.0
9.25/–– – (Takeshi et al., 2006)
Japan(18)
Living roomnd-1,507
–/11.4nd-136 –/1.30
nd-1,260 –/1.90
nd-0.60 (Saito et al., 2007)
Japan(41)
Residential detached house –<12.6-297
–/15.515.5-2,660
–/89.2<11.5-61.4
–/<11.5(Kanazawa et al.,
2010)
Japan(6)
Home450-1,120 763/735
– – – (Otake et al., 2001)
OfficeSweden(4)
Office building 101/– 11.0/– 44.4/– – (Carlsson et al., 1997)
Sweden(3)
Lecture room/office –3.00-12.06.33/4.00
91.0-850517/610
–(Björklund et al.,
2004)Sweden(1)
Linoleum floor, new photocopier
950 730 160 35.0(Marklund et al.,
2005a)Sweden(3)
Computer, desk, chair with polyurethane foam upholstery
65.0-922 380/154
6.00-870 300/25.0
41.0-120 72.0/55.0
–(Staaf and Östman,
2005)Sweden(10)
Office/mechanical workshop108-460 222/234
nd-140 21.0/10.0
16.0-240 110/100
nd-73.0 24.0/28.0
(Bergh et al., 2011)
Switzerland(4)
Office7.37-169 68.8/49.4
6.10-56.0 28.8/26.5
nd-130 –(Hartmann et al.,
2004)Norway(2)
Office building 2,410-36,000 2.70-23.0 10.0-21.0 <0.40-7.10 (Green et al., 2008)
Finland b Office/coffee room 50.0-150 <3.00-200 <9.00-40.0 <40.0 (Mäkinen et al., 2009)
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32
33
(4) 90.0/– 8.00/– 20.0/–Japan(14)
Office building0.90-260
–/20.1nd-42.1 –/3.30
nd-57.6 –/6.00
nd-8.70 (Saito et al., 2007)
China(90)
Common office furniture, not adjacent to industrial activity or main traffic roads
5.00-148 45.5/17.2
1.03-13.4 4.91/3.11
0.83-81.0 24.2/7.76
0.04-14.3 2.25/0.63
(Yang et al., 2014)
School buildingSweden(12)
School building 213/– 104/– 41.6/– – (Carlsson et al., 1997)
Sweden(1)
Laboratory, linoleum floor 36.0 0.70 31.0 <0.30(Marklund et al.,
2005a)Sweden(1)
University lobby, corridor with sofas
470 2.00 440 1.70(Marklund et al.,
2005a)Sweden(1)
Library, bookshelves, computer
640 590 40.0 <0.70(Marklund et al.,
2005a)Finland c
(3)Computer classroom
50.0-280 90.0/–
70.0-140 100/–
130-200 160/–
<40.0 (Mäkinen et al., 2009)
HotelSweden(1)
Wooden floor, bed, armchair 81.0 2.20 69.0 <0.60(Marklund et al.,
2005a)Day care centerSweden(4)
Day care center 233/– 144/– 52.9/– – (Carlsson et al., 1997)
Sweden(1)
PVC floor covering 96.0 2.50 28.0 59.0(Marklund et al.,
2005a)
Sweden Playroom area 110-580 7.80-230 1.30-72.0 nd-30.0 (Bergh et al., 2011)
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34
35
(10) 282/224 47.0/25.0 19.0/8.40 6.70/–Health care facility/hospitalSweden(3)
Health care facility, sparsely furnished
60.0-767 380/347
9.00-350 132/35.0
26.0-750 305/140
–(Staaf and Östman,
2005)Sweden(1)
Hospital ward, PVC floor covering, two beds
550 320 69.0 150(Marklund et al.,
2005a)StoreSwitzerland(5)
Electronic store4.30-40.0 25.7/26.5
2.20-22.0 11.8/8.20
nd –(Hartmann et al.,
2004)Switzerland(2)
Furniture store74.1-84.1
79.1/–6.30-11.9
9.10/–46.0-57.0
51.1/––
(Hartmann et al., 2004)
Sweden(1)
Radio shop, PVC floor covering
58.0 29.0 10.0 <0.40(Marklund et al.,
2005a)Sweden(1)
Textile shop, tiled floor 70.0 3.40 32.0 <0.20(Marklund et al.,
2005a)Sweden(1)
Furniture shop, wall-to-wall carpet, tiled floor
160 11.0 73.0 0.80(Marklund et al.,
2005a)Sweden(4)
Electronic equipment, bicycles, clothes and carpets
26.0-113 57.7/34.0
11.0-56.0 33.5/33.5
1.00-96.0 30.5/12.5
–(Staaf and Östman,
2005)Norway(2)
Sporting-goods shop 2,450-47,100 3.50-5.80 27.0-49.0 <0.40-18.0 (Green et al., 2008)
PrisonSweden(1)
Corridor, linoleum floor, no furniture
670 17.0 570 6.00(Marklund et al.,
2005a)Public recreation place
Switzerland Theater 136 36.0 63.0 – (Hartmann et al.,
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36
37
(1) 2004)Sweden(1)
Public dance hall, between dining area and dance floor
Finland e Dismantling and sorting 1,100-2,580 290-1,100 30.0-120 <60.0 (Mäkinen et al., 2009)
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38
39
(6) electronics 1,570/– 450/– 60.0/–
Finland c
(2)
Service of the crushing process, dismantling and sorting electronics
330-370 350/–
<3.00-20.0 6.00/–
<10.0 <40.0 (Mäkinen et al., 2009)
Finland e
(6)
Service of the crushing process, dismantling and sorting electronics
70.0-11,900 1,910/–
<3.00-520 40.0/–
<20.0-510 40.0/–
<30.0-450 90.0/–
(Mäkinen et al., 2009)
Vehicle
Switzerland(4)
Car12.8-270 133/124
nd-9.40 5.28/5.85
nd-260 118/107
–(Hartmann et al.,
2004)
Sweden(4)
Car, bus, subway car393-2,320
1,710/2,050nd-320 13.0/–
330-2,300 1,610/1,900
nd-5.00 1.25/–
(Staaf and Östman, 2005)
Garage
Sweden(3)
Car, bus, subway car9.00-354 148/81.0
nd-320 111/12.0
5.00-64.0 25.7/8.00
nd(Staaf and Östman,
2005)
Patch samples (ng/cm2) f
Finland(3)
Circuit board factory0.90-2.10
1.50/–<0.05-1.40
0.30/–<0.10 <0.60 (Mäkinen et al., 2009)
Finland(3)
Furniture workshop1.10-8.30
3.70/–<0.05-0.30
0.10/–<0.10 <0.60 (Mäkinen et al., 2009)
Finland(5)
Electronics recycling plant2.40-11.0
5.70/–0.20-1.50
0.40/–<0.10-1.30
0.20/–<0.60 (Mäkinen et al., 2009)
Finland(6)
Electronics recycling plant1.00-169
15.0/–<0.05-1.20
0.20/–<0.10 <0.60 (Mäkinen et al., 2009)
20
40
41
Hand wash sample (μg/hands) f
Finland(2)
Circuit board factory1.30-9.80
3.50/–<0.001 <0.004
<0.01-0.69 0.07/–
(Mäkinen et al., 2009)
Finland(2)
Furniture workshop27.0-43.0
34.0/–<0.001 <0.004 <0.01 (Mäkinen et al., 2009)
a Concentrations refer to 10th-90th range and geometric mean.b Geometric average concentrations for indoor air from three offices (a circuit board factory, a furniture workshop and an electronics dismantling facility) and one coffee room of an electronics dismantling facility.c Average concentrations for stationary air samples in geometric mean.d Workshops including a bakery, a newspaper printing press and an electronics dismantling facility.e Average concentrations for personal air samples in geometric mean.f Average concentrations in geometric mean.The full names for the halogenated OPs are obtained in Table 1. –: data not available. nd: not detected.
21
42
48
49
50
51
52
53
54
55
43
Table S4Comparison of the concentrations (range; arithmetic mean/median; ng/m3) of the predominant non-halogenated OPs in air from various indoor environments worldwide.
Location (no.) a TEP TPP TNBP TIBP TMPP TPHP TBOEP TEHP EHDPP Ref
a The arrangement and detailed descriptions of the matrices are in agreement with Table S3 without specification.b Concentrations refer to 10th-90th range and geometric mean.c Average concentrations for stationary air samples in geometric mean.d Average concentrations for personal air samples in geometric mean.
27
54
59
60
61
62
55
e Samples from workshops for recycling of printed circuit boards.f Average concentrations in geometric mean.The full names for the halogenated OPs are listed in Table 1. –: data not available. nd: not detected.
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56
63
64
65
57
Table S5Comparison of the concentrations (range; arithmetic mean/median; pg/m3) of ΣOP and the major halogenated OPs in outdoor air from different regions around the world.
Location (no.)Description of
matrixΣOP TCEP TCIPP TDCPP Ref
Urban area
Japan (25) aBack yard of the houses, summer
–4,570-58,400
14,300/–– – (Takeshi et al., 2006)
Japan (21) aBack yard of the houses, winter
–2,600-11,700
6,590/–– – (Takeshi et al., 2006)
Japan (8)Verandas and
below the eavesnd-8,300 – nd-3,100 – (Saito et al., 2007)
Norway (6) Near main roads1,370-20,300 6,970/3,120
510-6,200 2,390/1,450
240-3,700 1,320/490
<40.0-72.047.0/<40.0
(Green et al., 2008)
USA (27) Urban sites270-4,450
1,500/1,390180/120 530/410 120/79.0 (Salamova et al., 2014b)
USA (22) Urban sites110-8,100
2,100/1,310120/110 850/320 520/110 (Salamova et al., 2014b)
Remote area
Finland (1)Background air
from remote area13,000 2.00 810 20.0 (Marklund et al., 2005c)
Norway (7) Remote areas119-1,100 410/230
<200-270 124/<200
<200-330 133/<200
<40.0-250 124/<200
(Green et al., 2008)
Sturgeon Point, USA (16)
Rural and remote sites
30.0-1,100 34.0/21.0
130/150 170/72.0 28.0/28.0 (Salamova et al., 2014b)
Sleeping Bear Dunes, Rural and remote 22.0-27.0 11.0/8.00 25.0/27.0 nd (Salamova et al., 2014b)
29
58
66
67
68
59
USA (16) sites 12.0/11.0Eagle Harbor, USA (26)
Rural and remote sites
13.0-740 170/100
6.00/6.00 32.0/29.0 52.0/32.0 (Salamova et al., 2014b)
European Arctic (34)Atmospheric
particle33.0-1,450
426/3344.00-63.0 19.0/15.0
10.0-186 62.0/57.0
2.30-294 59.0/10.0
(Salamova et al., 2014a)
Sea areaGerman North Sea (20)
Marine atmosphere
109-1420 513/370
6.00-16342.9/30.5
38.0-1,200332/271
nd-78.06.05/–
(Möller et al., 2011)
The West Pacific, Ocean (11)
Marine aerosols –0.90-130
30.0/–0.20-9.00
1.20/–0.75-830
130/–(Cheng et al., 2013)
Southern Ocean near Antarctica (20)
Marine aerosols –0.70-40.0
6.00/–0.10-4.00
0.89/–0.80-78.0
11.0/–(Cheng et al., 2013)
The Pacific, Indian, Arctic, Southern Ocean (30)
Marine aerosols110-2,900 700/550
20.0-2,000 280/190
20.0-620 250/210
nd-780 80.0/40.0
(Mo ̈ller et al., 2012)
Arctic Ocean (6) Marine aerosols220-1,400 690/540
170-590 360/290
90.0-530 270/280
nd-7.00 (Mo ̈ller et al., 2012)
Northern Pacific Ocean (3)
Marine aerosols290-630 470/480
160-280 220/200
100-270 180/170
5.00-8.00 6.00/5.00
(Mo ̈ller et al., 2012)
Sea of Japan (2) Marine aerosols450-2,900
1,680/–240-1,960
1,100/–130-620
380/–20.0-50.0
30.0/–(Mo ̈ller et al., 2012)
Indian Ocean (15) Marine aerosols110-1,200 630/590
Black Sea (4) Marine aerosols1,720-6,170 2,970/2,010
308-2,420 928/492
539-2,720 1,230/820
nd-96.9 60.3/72.1
(Castro-Jimenez et al., 2014)
a Concentration refers to 10th-90th range and geometric mean.The full names for the halogenated OPs are obtained in Table 1. –: data not available. nd: not detected.
31
62
69
70
63
Table S6Comparison of the concentrations (range; arithmetic mean/median; pg/m3) of the predominant non-halogenated OPs in outdoor air from different regions worldwide.
Location (no.) a TEP TPP TNBP TIBP TPHP TBOEP TEHP RefUrban area
Japan (25) b – –6,000-33,000
13,700/–– – – – (Takeshi et al., 2006)
Japan (21) b – –6,000-24,100
9,270/–– – – – (Takeshi et al., 2006)
Japan (8) nd-1,400 – nd-1,700 – – nd-1,100 – (Saito et al., 2007)
Norway (6) – –300-3,700 1,270/570
320-4,400 1,250/410
<50.0-1,000132/<70.0
<100-340133/200
– (Green et al., 2008)
USA (27) – – 250/180 – 140/110 320/260 41.0/42.0 (Salamova et al., 2014b)
USA (22) – – 150/130 – 200/180 330/230 66.0/57.0 (Salamova et al., 2014b)
Remote area
Finland (1) – – 280 – 12,000 - – (Marklund et al., 2005c)
a The arrangement and detailed descriptions of the matrices are in line with Table S5 without specification.b Concentration refers to 10th-90th range and geometric mean.The full names for the non-halogenated OPs are obtained in Table 1. –: data not available. nd: not detected.
34
68
74
75
76
69
Table S7Comparison of the concentrations (range; arithmetic mean/median; ng/L) of ΣOP and the predominant halogenated OPs in waters and precipations available around the world.
Location (no.) Description of matrix ΣOP TCEP TCIPP TDCPP RefSewage treatment plant (STP) influent waste water Germany(1)
Municipal STP 38,900 21,100 – –(Fries and Püttmann,
Municipal STP 35,800 33,800 – –(Fries and Püttmann,
2001)Germany(3)
Municipal STP 2,030-7,510 3,930/2,250
214-557 352/286
– –(Fries and Püttmann,
2003)
35
70
77
78
79
71
Germany(1)
Industrial STP 397 nd – –(Fries and Püttmann,
2003)Germany(5)
Population equivalents: 300,000
– –230-610 380/330
– (Bester, 2005)
Germany(11)
Effluent – 5.00-130 50.0-400 20.0-120(Andresen et al.,
2004)Germany(18)
Population equivalents: 1,100,000
–up to 470
357/–680-6,600
2,270/–up to 310
137/–(Meyer and Bester,
2004)Austria(5)
Population equivalents <10,000
–43.0-1,600 391/74.0
350-1,000 560/460
23.0-260 85.0/53.0
(Martínez-Carballo et al., 2007)
Austria(7)
Population equivalents: 10,000-100,000
–80.0-150 110/100
310-960 730/580
27.0-160 81.0/74.0
(Martínez-Carballo et al., 2007)
Austria(4)
Population equivalents >1,000,000
–<8.80-140 67.0/61.0
270-1,400 733/630
19.0-1,400 387/65.0
(Martínez-Carballo et al., 2007)
Spain(11)
Population equivalents: 1,000-500,000
–81.0-810 380/382
100-4,800 810/812
9.20-81.0 44.0/46.0
(Rodil et al., 2012)
Sweden(3)
Municipal and industrial STP
–<500-36,000
22,700/32,000<500-4,000 2,330/3,000
<500-3,000 1,330/1,000
(Paxéus, 1996)
Sweden(8)
Population equivalents: 3,400-775,000
7,900-39,000 9,790/6,750
350-890 504/465
1,500-24,000 4,690/2,000
130-340 225/210
(Marklund et al., 2005b)
Western Europe(13)
Population equivalents: 3,400-1,600,000
– 200/– 600/– –(Reemtsma et al.,
2006)Norway(3)
Population equivalents: 45,000-290,000
–1,600-2,2001,800/1,600
1,700-2,100 1,900/1,900
86.0-740 499/670
(Green et al., 2008)
South Korea(7)
Industrial and Municipal STP
–92.0-2,620
537/–– – (Kim et al., 2007)
36
72
73
Raw water from sea-based solid waste disposal site
Japan(12)
Waste disposal site23,400-157,000 59,400/28,300
4,230-87,400 24,800/8,260
11,300-48,200
2,3500/16,200
680-6,180 2,290/1,180
(Kawagoshi et al., 1999)
Japan(12)
Surrounding sea50.0-8,750 2,420/1,570
up to 4,640 1,400/930
up to 3,060 872/510
up to 200 140/150
(Kawagoshi et al., 1999)
River waterJapan(–)
River and sea water – 14.0-347 16.0-176 –(Ishikawa et al.,
1985)USA(139)
Stream waterup to 540
–/100up to 160
–/100– – (Kolpin et al., 2002)
Germany(51)
Rhine, Elbe, Main, Oder, Nidda and Schwarzbach
River, river shores
519-1,870 932/665
17.0-220 84.6/36.0
– –(Fries and Püttmann,
2001)
Germany(14)
Oder River190-2,820
1,280/1,260nd-1,240 317/220
– –(Fries and Püttmann,
2003)Germany(26)
Ruhr River – 13.0-130 20.0-200 27.0-57.0(Andresen et al.,
2004)Germany(5)
Rhine River – – 80.0-100 13.0-36.0 (Andresen et al., 2004)
Germany(1)
Lippe River – – 100 17.0(Andresen et al.,
2004)USA(18)
Stream water –48.0-700
–/195–
100-400 –/200
(Haggard et al., 2006)
South Korea(8)
The Youngsan, the Nakdong and Han River
–14.0-81.0
42.0/–– – (Kim et al., 2007)
37
74
75
Austria(4)
Danube, Schwechat and Liesing River
141-922 438/345
13.0-130 50.8/30.0
33.0-170 89.0/76.5
<3.00-19 13.7/15.0
(Martínez-Carballo et al., 2007)
Italy(2)
Tiber River – nd-7.00 54.0-117 –(Bacaloni et al.,
2007)Spain(28)
Along the Mero river basin –up to 56.0 6.80/7.20
up to 720 65.0/69.0
nd (Rodil et al., 2012)
Germany(16)
Elbe, Weser, Ems, Rhine, Meuse and Scheldt River
58.3-1,090 402/381
3.29-69.9 22.9/18.7
24.3-570 146/128
5.30-67.0 22.5/18.9
(Bollmann et al., 2012)
Germany(53)
Elbe River85.4-511 227/214
–31.0-305 94.4/65.2
–(Bollmann et al.,
2012)UK(13)
Aire River113-26,300 6,030/2,760
119-316167/181
113-26,100 6,040/–2,500
62.0-14974.3/74.0
(Cristale et al., 2013b)
Spain(32)
Arga, Nolón and Besòs River, source to mouth
up to 7,200 1,490/110
<1.50-330 85.0/16.0
<7.20-1,800 445/69.0
<5.30-200 91.7/100
(Cristale et al., 2013a)
Marine waterMediterranean coast (6)
Coastal waternd-1,250 339/175
nd-400 117/–
– –(Barceló et al.,
1990)North Sea(15)
Marine water – –0.90-7.90 3.78/3.10
– (Weigel et al., 2005)
German Bight, North Sea (14)
Offshore water6.90-37.016.6/14.7
1.00-6.00 2.76/2.80
5.00-28.1 12.2/10.8
0.90-2.80 1.61/1.20
(Andresen et al., 2007)
Germany Bight(18)
Marine water from German Bight
5.00-50.0 – 3.00-28.0 –(Bollmann et al.,
2012)Pearl River Delta, China (23)
Coastal water, dry season2,040-3,120 2,620/2,750
400-640 504/495
470-1,150 761/750
– (Wang et al., 2014)
38
76
77
Pearl River Delta, China(23)
Coastal water, wet season 1,080-2,500 1,520/1,360
220-1,160 421/320
150-570 328/295
– (Wang et al., 2014)
China (13)
Seawater from Yellow Sea and East China Sea
91.9-1390 440/342
21.0-618 134/55.2
15.8-170 88.9/84.1
24.0-378 115/88.5
(Hu et al., 2014)
Lake waterGermany a
(42)Urban lentic surface water –
9.00-66.0 –/23.0
27.0-175 –/85.0
–(Regnery and
Püttmann, 2010a)Germany a
(41)Urban lentic surface water –
14.0-184 –/61.0
52.0-379 –/126
–(Regnery and
Püttmann, 2010a)Central Italy b
(13)Volcanic lakes, surrounded by houses and bath resorts
55.0-1,530 562/326
nd-27.010.5/9.00
6.00-62.024.0/19.0
5.00-67876.7/20.0
(Bacaloni et al., 2008)
Germany a
(2)Remote lentic surface water –
<3.00-15.0 –/3.00
<4.00-46.0 –/14.0
–(Regnery and
Püttmann, 2010a)Germany a
(20)Remote lentic surface water –
<3.00-9.00 –/3.00
<4.00-32.0 –/7.00
–(Regnery and
Püttmann, 2010a)Germany a
(20)Remote lentic surface water –
<3.00-27.0 –/3.00
<4.00-115 –/18.0
–(Regnery and
Püttmann, 2010a)Germany(2)
Montan lake – 6.00/– 31.0/– –(Regnery and
Püttmann, 2010a)Germany(2)
Montane reservoir, close to a road and a campground
– 33.0/– 312/– –(Regnery and Püttmann,
2010a)Central Italy b
(13)Volcanic lakes, unspoiled
environment33.0-134 61.5/48.0
nd-5.000.38/nd
nq-5.002.08/2.00
nd-23.05.23/2.00
(Bacaloni et al., 2008)
Drinking water sourceUSA Source water for drinking- – up to 120 – up to 110 (Stackelberg et al.,
39
78
79
(12) water treatment 95.0/– 102/– 2007)Germany(4)
Montane reservoir, drinking water supply
– 18.5/– 45.0/– –(Regnery and Püttmann,
2010a)
Central Italy b
(13)
Volcanic lakes, affected by agricultural and tourism
activities
22.0-2,110 401/167
nd-64.012.5/nd
2.00-27.011.8/10.0
nd-35.012.4/7.00
(Bacaloni et al., 2008)
South Korea(2)
Lake water near intake points for water supply of
Seoul and Gwangju– 14.0-25.0 – - (Kim et al., 2007)
Drinking waterUSA(4)
Finished water from drinking-water treatment
–70.0-99.086.0/87.5
–150-250190/181
(Stackelberg et al., 2004)
USA(12)
Finished water from drinking-water treatment
–up to 50.0
4.00/––
up to 70.0 12.0/–
(Stackelberg et al., 2007)
South Korea(2)
Finished water from drinking-water treatment
– <10.0 – – (Kim et al., 2007)
Spain(24)
Metropolitan area, private homes
–up to 47.0 7.20/<7.30
29.0-200 57.0/62.0
nd (Rodil et al., 2012)
China(39)
Tap water, inland/coastal and developed/less
developed cities
85.1-325 165/–
14.4-83.212.5/–
14.4-83.233.4/–
1.50-3.502.50/–
(Li et al., 2014)
Ground waterGermany (45)
Water from wells –1.00-754
–/50.0– –
(Fries and Püttmann, 2001)
Germany (76)
Water from wells154-1,770 747/620
nd-312 150/108
– –(Fries and Püttmann,
2003)
40
80
81
Italy(9)
Water from wells –nd-8.000.89/–
nd-12.02.33/–
nd(Bacaloni et al.,
2008)Rain waterGermany (1)
Rain water from urban area
1,390 79.0 – –(Fries and Püttmann,
2001)Germany(1)
Rain water from urban area
1,430 121 – –(Fries and Püttmann,
2003)Germany(2)
Roof runoff from urban area
869-1,500 80.0-148 – –(Fries and Püttmann,
2003)Germany(26)
Rain water from urban area
–up to338–/73.0
46.0-2,660 –/743
up to 32.0–/7.00
(Regnery and Püttmann, 2009)
Germany (90)
Rain water from urban area
–10.0-485
–/71.032.0-3,560
–/403<1.00-532
–/5.00(Regnery and
Püttmann, 2010b)Germany (42)
Storm water holding tank, urban area
–33.0-275
–/77.016.0-5,790
–/880<1.00-73.0
–/13.0(Regnery and
Püttmann, 2010b)Italy(2)
Rome, urban area1,440-1,650
1,550/–149-161
155/–633-739
686/–360-448
404/–(Bacaloni et al.,
2008)Germany(27)
Rain water from sparsely populated area
–up to 390
53.7/–up to 1150
139/–up to 53.0
–/17.0(Regnery and
Püttmann, 2009)Germany(29)
Rain water from rural area
–11.0-390
–/40.0<1.00-497
–/16.0<1.00-497
–/16.0(Regnery and
Püttmann, 2010b)Germany (48)
Rain water from small village
–<2.00-127
–/12.05.00-1,210
–/134<1.00-87.0
–/7.00(Regnery and
Püttmann, 2010b)Germany(10)
Storm water holding tank, small village
–23.0-131
–/78.0197-4,850
–/410<1.00-36.0
–/11.0(Regnery and
Püttmann, 2010b)Italy From a parking site near 234 19.0 28.0 108 (Bacaloni et al.,
41
82
83
(1) Martignano Lake 2008)Ireland(-)
Rain water from seashore in remote area
– 1.00-21.0 1.00-4.50 –(Laniewski et al.,
1998)Snow (ng/kg)Poland and Sweden (-)
Snow 1,000-4,500 – – –(Laniewski et al.,
1998)Finland(7)
Snow from remote areas130-26,000 9,300/430
7.00-39.0 20.0/12.0
70.0-210 130/120
4.00-230 40.0/10.0
(Marklund et al., 2005c)
Finland(3)
Snow from airport13,000-26,000 21,300/25,000
29.0-39.0 350/370
100-210 140/120
4.00-20.0 8.00/5.00
(Marklund et al., 2005c)
Finland(3)
Snow from road intersection150-430 330/400
7.00-10.0 9.00/8.00
110-170 140/130
8.00-230 80.0/10.0
(Marklund et al., 2005c)
Finland(1)
Snow from a forested area 130 7.00 70.0 30.0(Marklund et al.,
2005c)Germany d
(42)Snow from sparsely
populated area–
up to 488–/42.0
up to 385–/73.0
up to 113–/23.0
(Regnery and Püttmann, 2009)
Finland e
(1)Deposition from Pallas 1,300 550 510 –
(Marklund et al., 2005c)
a Concentration range for 5th-95th range.b Concentration ranges for mean values.c Concentration ranges refer to median levels.d Concentration in ng/L for deposition flux.e Concentration in ng/m2/d for deposition flux.The full names for the halogenated OPs are obtained in Table 1. –: data not available. nd: not detected. nq: not quantified.
42
84
80
81
82
83
84
85
85
Table S8
Comparison of the concentrations (range; arithmetic mean/median; ng/L) of the predominant non-halogenated OPs in waters and precipations from different regions around the world.
Location (no.) a TEP TPP TMPP TNBP TIBP TBOEP TPHP TEHP Ref
12.0 2.00 2.00 11.0 6.00 38.0 8.00 –(Bacaloni et al.,
2008)
48
96
97
Japan f
(8)– –
1.00-97.0 30.0/–
– – – – – (Cho et al., 1996)
Japan g
(–)– –
18,500-101,000 61,000/–
– – – – – (Cho et al., 1996)
Japan h
(4)– –
33.0-87.0 59.5/58.9
– – – – –(Takimoto et al.,
1999)Snow (ng/kg)Finland(7)
– –nd-9,900 3,650/430
10.0-25,000 7,170/20.0
–2.00-90.0 20.0/7.00
4.00-830 220/70.0
nd-130 60.0/50.0
(Marklund et al., 2005c)
Finland(3)
– –260-9,900 3,650/780
2,100-25,000 16,700/23,000
–7.00-90.0 40.0/30.0
120-830 500/540
1.00-100 30.0/8.00
(Marklund et al., 2005c)
Finland(3)
– – nd10.0-20.0 20.0/10.0
–4.00-10.0 7.00/6.00
4.00-70.0 30.0/7.00
nd-130(Marklund et al.,
2005c)Finland(1)
– – – 20.0 – 2.00 4.00 –(Marklund et al.,
2005c)Germany i
(42)– – –
up to 458–/64.0
up to 458–/100
up to 242–/17.0
– –(Regnery and
Püttmann, 2009)Finland j
(1)– – – 230 – – – –
(Marklund et al., 2005c)
Oil product (μg/g)Finland(14
– – <0.30-12,000 <0.50-190,000 – – <0.30-8.90 <0.30-4.20(Marklund et al.,
2005c)a The arrangement and detailed descriptions of the matrices are in accordance with Table S7 without specification.b River water collected from Kurose River, Japan.c Concentrations refer to 5th-95th range for lake water from urban areas. d Concentration ranges for mean values.
49
98
89
90
91
92
99
e Concentration ranges for median levels. f Rain water collected from rooftop on a campus in Hiroshima.g Rainfall drop from a greenhouse.h Rain water collected from Kurose river basin.i Concentration in ng/L for snow samples.j Concentration in ng/m2/d for deposition flux.The full names for the non-halogenated OPs are available in Table 1. –: data not available. nd: not detected. nq: not quantified.
50
100
93
94
95
96
97
98
99
101
Table S9
Comparison of the concentrations (range; arithmetic mean/median; ng/g) of ΣOP and the dominant halogenated OPs in sludge, sediment and soil samples from different regions around the world.
Location (no.) Description of matrix ΣOP TCEP TCIPP TDCPP RefSludge from sewage treatment plant
Norway (2)Population equivalents: 45000-290000
3,870-4,810 <9.00 650-944 110-330 (Green et al., 2008)
Sweden (17)Population equivalents: 3400-775000
620-6,900 4,240/4,400
6.60-110 40.9/36.0
61.0-1,900 874/790
3.00-260 79.8/41.0
(Marklund et al., 2005b)
Spain (5) Primary sludge – nd820-2,900
–/920300-600
–/310(Cristale and
Lacorte, 2013)
Spain (5) Biology sludge – nd600-950
–/81092.0-600
–/110(Cristale and
Lacorte, 2013)
Germany (20) Sludge – –1,000-21,000
5,100/–– (Bester, 2005)
South China (19) Sludge96.7-1,310
420/2666.90-17.1 11.8/11.4
6.30-54.4 20.5/15.9
11.8-64.0 23.4/18.9
(Zeng et al., 2014)
Sediment
Germany (37)Elbe River, highly industrialized areas
–<1.00-41.0
–/7.405.90-311
–/57.0<1.00-13.0
–/7.90(Stachel et al., 2005)
Austria (4) River sediment2.40-1,940
583/196nd-160
<0.61-1,300 472/95.0
nd(Martínez-Carballo
et al., 2007)
Spain (–)River and marine sediments
– 45.9/– 38.0/– –(García-López et al.,
2009a)Spain and USA (–)
River sediments – – 4.0-10 –(García-López et al.,
2009b)
51
102
100
101
102
103
Spain (21) River sediments3.80-824 151/79.0
<2.70-9.70 6.02/5.15
<4.50-365 116/85.0
<1.90-12.0 8.00/8.40
(Cristale et al., 2013a)
Spain (5) River sediments –6.80-10.0
–/7.2092.0-600
–/3503.80-8.50
–/7.20(Cristale and
Lacorte, 2013)
Norway (8) River sediments486-22,500 4,980/1,920
<63.0-1,600 566/475
63.0-16,000 2,860/655
63.0-870 320/215
(Green et al., 2008)
Norway (4) In pump pit at landfill7,460-17,900 11,200/9,660
27.0-380 191/179
490-1,300 838/780
1,500-4,100 2,980/3,150
(Green et al., 2008)
Norway (4)From automobile destruction sites
22,700-33,800 27,000/25,900
2,300-5,500 3,330/2,750
9,500-24,000 14,600/12,50
0
<250-8,800 5,430/5,300
(Green et al., 2008)
Japan (33)Bottom sediments from waste disposal site
up to 10,900 1,930/1,040
up to 7,400 780/145
up to 1,180 115/10.0
up to 709 52.4/–
(Kawagoshi et al., 1999)
Taiwan (5)River and marine sediments
1.00-12.6 7.38/9.00
nd-1.50 1.02/1.20
nd-9.50 4.52/4.70
nd-1.10 0.34/nd
(Chung and Ding, 2009)
China (28) From Taihu Lake3.38-14.3 7.88/7.99
0.62-3.17 1.75/1.66
0.40-2.27 1.41/1.47
<0.30-5.54 1.31/1.03
(Cao et al., 2012)
Soil
Germany (6)From the university campus in Osnabrueck
– 4.96/– 1.23/– <0.07(Mihajlović et al.,
2011)
The full names for the halogenated OPs are displayed in Table 1. –: data not available. nd: not detected.
52
104
103
105
Table S10
Comparison of the concentrations (range; arithmetic mean/median; ng/g) of the major non-halogenated OPs in sludge, sediment and soil samples from different regions around the world.
Location (no.) a TEP TPP TMPP TNBP TIBP TPHP TBOEP TEHP EHDPP Ref
a The arrangement and detailed descriptions of the matrices are in agreement with Table S9 without specification.b Sediments from Havel and Spree River.c Soil from Air Force Based Top soils around a greenhouse.The full names for the non-halogenated OPs are obtained in Table 1. –: data not available. nd: not detected.
55
110
107
108
109
110
111
111
Table S11Comparison of the concentrations (range; arithmetic mean/median; ng/g lipid weight) of ΣOP and the predominant halogenated OPs in biota samples from different regions.
Marine eelpout 15,000/– 59.0/– 310/– <8.10(Sundkvist et al.,
2010)Sweden (5)
Marine salmon 34.0/– 1.50/– 23.0/– <1.10(Sundkvist et al.,
2010)Sweden (60)
Freshwater perch, background350-1,000
–/720nd-83.0 –/51.0
220-750 –/535
<9.60-<16.0(Sundkvist et al.,
2010)Sweden(27)
Freshwater perch, close to sources
1,600-11,000 –/1,900
39.0-160 –/51.0
170-770 –/320
49.0-140 –/55.0
(Sundkvist et al., 2010)
Sweden(2)
Freshwater carp, close to sources
1,600/– 23.0/– 110/– 36.0/–(Sundkvist et al.,
2010)Philippines (31)
Demersal fishes230-1,900 784/680
– – – (Kim et al., 2011a)
Philippines (28)
Pelagic fishes110-760 394/370
– – – (Kim et al., 2011a)
PRD, China (14)
Fishes (catfish and grass carp) – 82.7-4,690 62.7-883 nd-251 (Ma et al., 2013)
56
112
112
113
114
113
PRD, China (12)
Domestic birds (chicken and duck)
– 33.7-162 3.89-21.4 nd-43.7 (Ma et al., 2013)
Sweden (286)
Human milk46.0-180
–/99.02.10-8.20
–/4.9022.0-82.0
–/45.01.60-5.30
–/4.30(Sundkvist et al.,
2010)USA (9)
Pine needles<2.50-2,600
654/43.2<2.50-1,950
324/14.6<2.50-863 107/<2.50
<2.50-1,320 223/<19.8
(Aston et al., 1998)
The full names for the halogenated OPs are obtained in Table 1. –: data not available. nd: not detected.
57
114
115
115
Table S12Comparison of the concentrations (range; arithmetic mean/median; ng/g lipid weight) of the main non-halogenated OPs in biota samples from different regions.
al., 2010)a The arrangement and detailed descriptions of the matrices are in line with Table S11 without specification.b Fishes including bluetail mullet, coral grouper and flathead grey mullet.c Fish tissues.The full names for the non-halogenated OPs are detailed in Table 1. –: data not available. nd: not detected.
59
118
119
120
121
122
119
Table S13Reference doses (RfD) values (ng/kg bw/d) and estimated exposure (ng/kg bw/d) under different scenarios to organophosphate compounds via
Human exposure were estimated based on mean (50 and 20 mg/d for toddler and adult, respectively) and high dust ingestion rates (200 and 50 mg/d for toddler and adult, respectively), and the minnum, P5, P50, P95 and maxium concentrations of OPs. –: data not available.
63
126
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127
127
ReferencesAbdallah, M.A., Covaci, A., 2014. Organophosphate flame retardants in indoor dust from
Egypt: Implications for human exposure. Environ. Sci. Technol. 48, 4782-4789.
Ali, N., Ali, L., Mehdi, T., Dirtu, A.C., Al-Shammari, F., Neels, H., Covaci, A., 2013. Levels and profiles of organochlorines and flame retardants in car and house dust from Kuwait and Pakistan: Implication for human exposure via dust ingestion. Environ. Int. 55, 62-70.
Ali, N., Dirtu, A.C., Van den Eede, N., Goosey, E., Harrad, S., Neels, H., Mannetje, A.t., Coakley, J., Douwes, J., Covaci, A., 2012. Occurrence of alternative flame retardants in indoor dust from New Zealand Indoor sources and human exposure assessment. Chemosphere 88, 1276-1282.
Ali, N., Van den Eede, N., Dirtu, A.C., Neels, H., Covaci, A., 2011. Assessment of human exposure to indoor organic contaminants via dust ingestion in Pakistan. Indoor Air.
Andresen, J.A., Grundmann, A., Bester, K., 2004. Organophosphorus flame retardants and plasticizers in surface waters. Sci. Total Environ. 332, 155-166.
Andresen, J.A., Muir, D., Ueno, D., Darling, C., Theobald, N., Bester, K., 2007. Emerging pollutants in the North Sea in comparison to Lake Ontario, Canada, data. Environ. Toxicol. Chem. 26, 1081-1089.
Araki, A., Saito, I., Kanazawa, A., Morimoto, K., Nakayama, K., Shibata, E., Tanaka, M., Takigawa, T., Yoshimura, T., Chikara, H., Saijo, Y., Kishi, R., 2014. Phosphorus flame retardants in indoor dust and their relation to asthma and allergies of inhabitants. Indoor Air 24, 3-15.
Aston, L.S., Noda, J., Seiber, J.N., Reece, C.A., 1998. Organophosphate flame retardants in needles of Pinus ponderosa in the Sierra Nevada foothills. Bull. Environ. Contam. Toxicol. 57, 859-866.
Bacaloni, A., Cavaliere, C., Foglia, P., Nazzari, M., Samperi, R., Laganà, A., 2007. Liquid chromatography/tandem mass spectrometry determination of organophosphorus flame retardants and plasticizers in drinking and surface waters. Rapid Commun. Mass Spectrom. 21, 1123-1130.
Bacaloni, A., Cucci, F., Guarino, C., Nazzari, M., Samperi, R., Lagana, A., 2008. Occurrence of organophosphorus flame retardant and plasticizers in three volcanic lakes of Central Italy. Environ. Sci. Technol. 42, 1898-1903.
Barceló, D., Porte, C., Cid, J., Albaigés, J., 1990. Determination of organophosphorus compounds in Mediterranean Coastal waters and biota samples using gas chromatography with nitrogen-phosphorus and chemical ionization mass spectrometric detection. Int. J. Environ. Anal. Chem. 38, 199-209.
Bergh, C., Torgrip, R., Emenius, G., Ostman, C., 2011. Organophosphate and phthalate esters in air and settled dust: A multi-location indoor study. Indoor Air 21, 67-76.
Bergh, C., Torgrip, R., Östman, C., 2010. Simultaneous selective detection of organophosphate and phthalate esters using gas chromatography with positive ion chemical ionization tandem mass spectrometry and its application to indoor air and dust. Rapid Commun. Mass Spectrom. 24, 2859-2867.
64
128
128
129130
131132133134
135136137138
139140
141142
143144145
146147148149
150151152
153154155156
157158159
160161162163
164165
166167168169
129
Bester, K., 2005. Comparison of TCPP concentrations in sludge and wastewater in a typical German sewage treatment plant–comparison of sewage sludge from 20 plants. J. Environ. Monit. 7, 509-513.
Bi, X.H., Simoneit, B.R.T., Wang, Z.Z., Wang, X.M., Sheng, G.Y., Fu, J.M., 2010. The major components of particles emitted during recycling of waste printed circuit boards in a typical e-waste workshop of South China. Atmosphere Environment 44, 4440-4445.
Björklund, J., Isetun, S., Nilsson, U., 2004. Selective determination of organophosphate flame retardants and plasticizers in indoor air by gas chromatography, positive-ion chemical ionization and collision-induced dissociation mass spectrometry. Rapid Commun. Mass Spectrom. 18, 3079-3083.
Bollmann, U.E., Moeler, A., Xie, Z.Y., Ebinghaus, R., Einax, J.W., 2012. Occurrence and fate of organophosphorus flame retardants and plasticizers in coastal and marine surface waters. Water Res. 46, 531-538.
Brommer, S., Harrad, S., Van den Eede, N., Covaci, A., 2012. Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples. J. Environ. Monit. 14, 2482-2487.
Campone, L., Piccinelli, A.L., Östman, C., Rastrelli, L., 2010. Determination of organophosphorous flame retardants in fish tissues by matrix solid-phase dispersion and gas chromatography. Anal. Bioanal. Chem. 397, 799-806.
Cao, S.X., Zeng, X.Y., Song, H., Li, H.R., Yu, Z.Q., Sheng, G.Y., Fu, J.M., 2012. Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China. Environ. Toxicol. Chem. 31, 1478-1484.
Carignan, C.C., McClean, M.D., Cooper, E.M., Watkins, D.J., Fraser, A.J., Heiger-Bernays, W., Stapleton, H.M., Webster, T.F., 2013. Predictors of tris(1,3-dichloro-2-propyl) phosphate metabolite in the urine of office workers. Environment International 55, 56-61.
Carlsson, H., Nilsson, U., Becker, G., Östman, C., 1997. Organophosphate ester flame retardants and plasticizers in the indoor environment: Analytical methodology and occurrence. Environ. Sci. Technol. 31, 2931-2936.
Carlsson, H., Nilsson, U., Östman, C., 2000. Video display units: An emission source of the contact allergenic flame retardant triphenyl phosphate in the indoor environment. Environ. Sci. Technol. 34, 3885-3889.
Castro-Jimenez, J., Berrojalbiz, N., Pizarro, M., Dachs, J., 2014. Organophosphate ester (OPE) flame retardants and plasticizers in the Open Mediterranean and Black Seas atmosphere. Environ. Sci. Technol. 48, 3203-3209.
Cheng, W.H., Xie, Z.Q., Blais, J.M., Zhang, P.F., Li, M., Yang, C.Y., Huang, W., Ding, R., Sun, L.G., 2013. Organophosphorus esters in the oceans and possible relation with ocean gyres. Environ. Pollut. 180, 159-164.
Cho, K.J., Hirakawa, T., Mukai, T., Takimoto, K., Okada, M., 1996. Origin and stormwater runoff of TCP (tricresyl phosphate) isomers. Water Res. 30, 1431-1438.
Cho, K.J., Takimoto, K., Okada, M., 1994. Fate of tricresyl phosphate isomers in Kurose River (Japan). Water Science Technology 30, 189-197.
65
130
170171172
173174175
176177178179
180181182
183184185
186187188
189190191
192193194195
196197198
199200201
202203204
205206207
208209
210211
131
Chung, H.-W., Ding, W.-H., 2009. Determination of organophosphate flame retardants in sediments by microwave-assisted extraction and gas chromatography-mass spectrometry with electron impact and chemical ionization. Anal. Chim. Acta 395, 2325-2334.
Cristale, J., García Vázquez, A., Barata, C., Lacorte, S., 2013a. Priority and emerging flame retardants in rivers: Occurrence in water and sediment, Daphnia magna toxicity and risk assessment. Environ. Int. 59, 232-243.
Cristale, J., Katsoyiannis, A., Sweetman, A.J., Jones, K.C., Lacorte, S., 2013b. Occurrence and risk assessment of organophosphorus and brominated flame retardants in the River Aire (UK). Environ. Pollut. 179, 194-200.
Cristale, J., Lacorte, S., 2013. Development and validation of a multiresidue method for the analysis of polybrominated diphenyl ethers, new brominated and organophosphorus flame retardants in sediment, sludge and dust. J. Chromatogr. A 1305, 267-275.
David, M.D., Seiber, J.N., 1999. Analysis of organophosphate hydraulic fluids in US Air Force base soils. Arch. Environ. Contam. Toxicol. 36, 235-241.
Dirtu, A.C., Ali, N., Van den Eede, N., Neels, H., Covaci, A., 2012. Country specific comparison for profile of chlorinated, brominated and phosphate organic contaminants in indoor dust. Case study for Eastern Romania, 2010. Environ. Int. 49, 1-8.
Dodson, R.E., Perovich, L.J., Covaci, A., Ionas, A.C., Dirtu, A.C., Brody, J.G., Rudel, R.A., 2012. After the PBDE phase-out: A broad suite of flame retardants in repeat house dust Samples from California. Environ. Sci. Technol. 46, 13056-13066.
Fries, E., Püttmann, W., 2001. Occurrence of organophosphate esters in surface water and ground water in Germany. J. Environ. Monit. 3, 621-626.
Fries, E., Püttmann, W., 2003. Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany). J. Environ. Monit. 5, 346-352.
García-López, M., Rodríguez, I., Cela, R., 2009a. Pressurized liquid extraction of organophosphate triesters from sediment samples using aqueous solutions. J. Chromatogr. A 1216, 6986-6993.
García-López, M., Rodríguez, I., Cela, R., Kroening, K.K., Caruso, J.A., 2009b. Determination of organophosphate flame retardants and plasticizers in sediment samples using microwave-assisted extraction and gas chromatography with inductively coupled plasma mass spectrometry. Talanta 79, 824-829.
García, M., Rodríguez, I., Cela, R., 2007. Microwave-assisted extraction of organophosphate flame retardants and plasticizers from indoor dust samples. J. Chromatogr. A 1152, 280-286.
Green, N., Schlabach, M., Bakke, T., Brevik, E.M., Dye, C., Herzke, D., Huber, S., Plosz, B., Remberger, M., Schoyen, M., Uggerud, H.T., Vogelsang, C., 2008. Screening of selected metals and new organic contaminants 2007, in: Norwegian Pollution Control Agency (Ed.).
Haggard, B.E., Galloway, J.M., Green, W.R., Meyer, M.T., 2006. Pharmaceuticals and other organic chemicals in selected north-central and northwestern Arkansas streams. J. Environ. Qual. 35, 1078-1087.
Harrad, S., Ibarra, C., Abdallah, M.A.E., Boon, R., Neels, H., Covaci, A., 2008. Concentrations of brominated flame retardants in dust from United Kingdom cars,
66
132
212213214
215216217
218219220
221222223
224225
226227228
229230231
232233
234235236
237238239
240241242243
244245246
247248249250
251252253
254255
133
houses and offices: causes of variability and implications for human exposure. Environ. Int. 34, 1170-1175.
Hartmann, P.C., Bürgi, D., Giger, W., 2004. Organophosphate flame retardants and plasticizers in indoor air. Chemosphere 57, 781-787.
Hu, M.Y., Li, J., Zhang, B.B., Cui, Q.L., Wei, S., Yu, H.X., 2014. Regional distribution of halogenated organophosphate flame retardants in seawater samples from three coastal cities in China. Mar. Pollut. Bull. In Press.
Ingerowski, G., Friedle, A., Thumulla, J., 2001. Chlorinated ethyl and isopropyl phosphoric acid triesters in the indoor environment - An inter-laboratory exposure study Indoor Air 11, 145-149.
Ishikawa, S., Taketomi, M., Shinohara, R., 1985. Determination of trialkyl and triaryl phosphates in environmental samples. Water Res. 19, 119-125.
Jones-Otazo, H.A., Clarke, J.P., Diamond, M.L., Archbold, J.A., Ferguson, G., Harner, T., Richardson, G.M., Ryan, J.J., Wilford, B., 2005. Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs. Environmental Science & Technology 39, 5121-5130.
Kanazawa, A., Saito, I., Araki, A., Takeda, M., Ma, M., Saijo, Y., Kishim, R., 2010. Association between indoor exposure to semi-volatile organic compounds and building-related symptoms among the occupants of residential dwellings. Indoor Air 20, 72-84.
Kawagoshi, Y., Fukunaga, I., Itoh, H., 1999. Distribution of organophosphoric acid trimesters between water and sediment at a sea-based solid waste disposal site. Journal of Material Cycles and Waste Management 1, 53-61.
Kim, J.-W., Isobe, T., Chang, K.-H., Amano, A., Maneja, R.H., Zamora, P.B., Siringan, F.P., Tanabe, S., 2011a. Levels and distribution of organophosphorus flame retardants and plasticizers in fishes from Manila Bay, the Philippines. Environ. Pollut. 159, 3653-3659.
Kim, J.-W., Isobe, T., Sudaryanto, A., Malarvannan, G., Chang, K.-H., Muto, M., Prudente, M., Tanabe, S., 2013. Organophosphorus flame retardants in house dust from the Philippines: occurrence and assessment of human exposure. Environ. Sci. Pollut. Res. 20, 812-822.
Kim, J.-W., Ramaswamy, B.R., Chang, K.-H., Isobe, T., Tanabe, S., 2011b. Multiresidue analytical method for the determination of antimicrobials, preservatives, benzotriazole UV stabilizers, flame retardants and plasticizers in fish using ultra high performance liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. A 1218, 3511-3520.
Kim, S.D., Cho, J., Kim, I.S., Vanderford, B.J., Snyder, S.A., 2007. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res. 41, 1013-1021.
Kolpin, D.W., Furlong, E.T., Meyer, M.T., Thurman, E.M., Zaugg, S.D., Barber, L.B., Buxton, H.T., 2002. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: A national reconnaissance. Environ. Sci. Technol. 36, 1202-1211.
Laniewski, K., Boren, H., Grimvall, A., 1998. Identification of volatile and extractable chloroorganics in rain and snow. Environ. Sci. Technol. 32, 3935-3940.
67
134
256257
258259
260261262
263264265
266267
268269270271
272273274
275276277
278279280
281282283284
285286287288289
290291292
293294295296
297298
135
Li, J., Yu, N.Y., Zhang, B.B., Jin, L., Li, M.Y., Hu, M.Y., Zhang, X.W., Wei, S., Yu, H.X., 2014. Occurrence of organophosphate flame retardants in drinking water from China. Water Res. 54, 53-61.
Mäkinen, M.S.E., Mäkinen, M.R.A., Koistinen, J.T.B., Pasanen, A.-L., Pasanen, P.O., Kalliokoski, P.I., Korpi, A.M., 2009. Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments. Environ. Sci. Technol. 43, 941-947.
Möller, A., Xie, Z.Y., Caba, A., Sturm, R., Ebinghaus, R., 2011. Organophosphorus flame retardants and plasticizers in the atmosphere of the North Sea. Environ. Pollut. 159, 3660-3665.
Ma, Y.Q., Cui, K.Y., Zeng, F., Wen, J.X., Liu, H., Zhu, F., Ouyang, G.F., Luan, T.G., Zeng, Z.X., 2013. Microwave-assisted extraction combined with gel permeation chromatography and silica gel cleanup followed by gas chromatography-mass spectrometry for the determination of organophosphorus flame retardants and plasticizers in biological samples. Anal. Chim. Acta 786, 47-53.
Marklund, A., Andersson, B., Haglund, P., 2003. Screening of organophosphorus compounds and their distribution in various indoor environments. Chemosphere 53, 1137-1146.
Marklund, A., Andersson, B., Haglund, P., 2005a. Organophosphorus flame retardants and plasticizers in air from various indoor environments. J. Environ. Monit. 7, 814-819.
Marklund, A., Andersson, B., Haglund, P., 2005b. Organophosphorus flame retardants and plasticizers in Swedish sewage treatment plants. Environ. Sci. Technol. 39, 7423-7429.
Marklund, A., Andersson, B., Haglund, P., 2005c. Traffic as a source of organophosphorus flame retardants and plasticizers in snow. Environ. Sci. Technol. 39, 3555-3562.
Martínez-Carballo, E., González-Barreiro, C., Sitka, A., Scharf, S., Gans, O., 2007. Determination of selected organophosphate esters in the aquatic environment of Austria. Sci. Total Environ. 388, 290-299.
Meeker, J.D., Stapleton, H.M., 2009. House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environmental Health Perspectives 118, 318-323.
Meyer, J., Bester, K., 2004. Organophosphate flame retardants and plasticisers in wastewater treatment plants. J. Environ. Monit. 6, 599-605.
Mihajlović, I., Vojinović Miloradov, M., Fries, E., 2011. Application of twisselmann extraction, SPME, and GC-MS to assess input sources for organophosphate esters into soil. Environ. Sci. Technol. 45, 2264-2269.
Mo ̈ller, A., Sturm, R., Xie, Z.Y., Cai, M.H., He, J.F., Ebinghaus, R., 2012. Organophosphorus flame retardants and plasticizers in airborne particles over the Northern Pacific and Indian Ocean toward the polar regions: Evidence for global occurrence. Environmental Science and Technology 46, 3127-3134.
Otake, T., Yoshinaga, J., Yanagisawa, Y., 2001. Analysis of organic esters of plasticizer in indoor air by GC-MS and GC-FPD. Environ. Sci. Technol. 35, 3099-3102.
Paxéus, N., 1996. Organic pollutants in the effluents of large wastewater treatment plants in Sweden. Water Res. 30, 1115-1122.
68
136
299300301
302303304305
306307308
309310311312313
314315
316317
318319
320321
322323324
325326327
328329
330331332
333334335336
337338
339340
137
Reemtsma, T., Weiss, S., Mueller, J., Petrović, M., González, S., Barceló, D., 2006. Polar pollutants entry into the water cycle by municipal wastewater: A European perspective. Environ. Sci. Technol. 40, 5451-5458.
Regnery, J., Püttmann, W., 2009. Organophosphorus flame retardants and plasticizers in rain and snow from Middle Germany. Clean-Soil, Air, Water 37, 334-342.
Regnery, J., Püttmann, W., 2010a. Occurrence and fate of organophosphorus flame retardants and plasticizers in urban and remote surface waters in Germany. Water Res. 44, 4097-4104.
Regnery, J., Püttmann, W., 2010b. Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff. Chemosphere 78, 958-964.
Ricking, M., Schwarzbauer, J., Franke, S., 2003. Molecular markers of anthropogenic activity in sediments of the Havel and Spree Rivers (Germany). Water Res. 37, 2607-2617.
Rodil, R., Benito Quintana, J., Concha-Graña, E., López-Mahía, P., Muniategui-Lorenzo, S., Prada-Rodríguez, D., 2012. Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain). Chemosphere 86, 1040-1049.
Saito, I., Onuki, A., Seto, H., 2007. Indoor organophosphate and polybrominated flame retardants in Tokyo. Indoor Air 17, 28-36.
Salamova, A., Hermanson, M.H., Hites, R.A., 2014a. Organophosphate and halogenated flame retardants in atmospheric particles from a European Arctic site. Environ. Sci. Technol. 48, 6133-6140.
Salamova, A., Ma, Y., Venier, M., Hites, R.A., 2014b. High levels of organophosphate flame retardants in the Great Lakes atmosphere. Environmental Science and Technology Letters 1, 8-14.
Sjo ̈din, A., Carlsson, H., Thuresson, K., Sjo ̈lin, S., Bergman, Å., Östman, C., 2001. Flame retardants in indoor air at an electronics recycling plant and at other work environments. Environ. Sci. Technol. 35, 448-454.
Staaf, T., Östman, C., 2005. Organophosphate triesters in indoor environments. J. Environ. Monit. 7, 883-887.
Stachel, B., Jantzen, E., Knoth, W., Kruger, F., Lepom, P., Oetken, M., Reincke, H., Sawal, G., Schwartz, R., Uhlig, S., 2005. The Elbe flood in August 2002-Organic contaminants in sediments samples taken after the flood event. Journal of Environmental Science and Health, Part A 40, 265-287.
Stackelberg, P.E., Furlong, E.T., Meyer, M.T., Zaugg, S.D., Henderson, A.K., Reissman, D.B., 2004. Persistence of pharmaceutical compounds and other organic wastewater contaminants in a conventional drinking-water-treatment plant. Sci. Total Environ. 329, 99-113.
Stackelberg, P.E., Gibs, J., Furlong, E.T., Meyer, M.T., Zaugg, S.D., Lippincott, R.L., 2007. Efficiency of conventional drinking-water-treatment processes in removal of pharmaceuticals and other organic compounds. Sci. Total Environ. 377, 255-272.
Stapleton, H.M., Klosterhaus, S., Eagle, S., Fuh, J., Meeker, J.D., Blum, A., Webster, T.F., 2009. Detection of organophosphate flame retardants in furniture foam and US house dust. Environmental Science and Technology 43, 7490-7495.
69
138
341342343
344345
346347348
349350
351352
353354355
356357
358359360
361362363
364365366
367368
369370371372
373374375376
377378379
380381382
139
Sundkvist, A.M., Olofssona, U., Haglunda, P., 2010. Organophosphorus flame retardants and plasticizers in marine and fresh water biota and in human milk. J. Environ. Monit. 12, 943-951.
Takeshi, O., Takashi, A., Yoshinori, S., Masahiro, F., 2006. Organic air pollutants inside and outside residences in Shimizu, Japan: Levels, sources and risks. Sci. Total Environ. 366, 485-499.
Takigami, H., Suzuki, G., Hirai, Y., Ishikawa, Y., Sunami, M., Sakai, S., 2009. Flame retardants in indoor dust and air of a hotel in Japan. Environ. Int. 35, 688-693.
Takimoto, K., Hirakawa, T., Ito, K., Mukai, T., Okada, M., 1999. Source and transport of tricresyl phosphate (TCP) isomers in Kurose river basin. Atmosphere Environment 33, 3191-3200.
Van de Eede, N., Dirtu, A., Neels, H., Covaci, A., 2011. Analytical developments and preliminary assessment of human exposure to organophosphate flame retardants from indoor dust. Environ. Int. 37, 454-461.
Wang, X.W., He, Y.Q., Lin, L., Zeng, F., Luan, T.G., 2014. Application of fully automatic hollow fiber liquid phase microextraction to assess the distribution of organophosphate esters in the Pearl River Estuaries. Sci. Total Environ. 470-471, 263-269.
Weigel, S., Bester, K., Hühnerfuss, H., 2005. Identification and quantification of pesticides, industrial chemicals, and organobromine compounds of medium to high polarity in the North Sea. Mar. Pollut. Bull. 50, 252-263.
Yang, F.X., Ding, J.J., Huang, W., Xie, W., Liu, W.P., 2014. Particle size-specific distributions and preliminary exposure assessments of organophosphate flame retardants in office air particulate matter. Environ. Sci. Technol. 48, 63-70.
Zeng, X.Y., He, L.X., Cao, S.X., Ma, S.T., Yu, Z.Q., Gui, H.Y., Sheng, G.Y., Fu, J.M., 2014. Occurrence and distribution of organophosphate flame retardants/plasticizers in wastewater treatment plant sludges from the Pearl River Delta, China. Environ. Toxicol. Chem. 33, 1720-1725.