Supplementary Information Enhanced tendon restoration effects of anti-inflammatory lactoferrin-immobilized heparin-polymeric nanoparticles on Achilles tendinitis rat model Hong Joon Choi a,b,1 , Somang Choi c,1 , Jae Gyoon Kim d,1 , Mi Hyun Song e , Kyu-Sik Shim e , Youn-Mook Lim f , Hak-Jun Kim e,* , Kyeongsoon Park g,* , Sung Eun Kim e,* a Department of Orthopedic Surgery, College of Medicine Korea University, Anam-dong, Seongbuk-gu, Seoul 02841, Korea b Yonsei gunwoo Hospital, #1814, Nambusunhwan-ro, Gwanak-gu, Seoul 08787, Korea c Department of Biomedical Science, College of Medicine Korea University, Anam-dong, Seongbuk-gu, Seoul 02841, Korea d Department of Orthopedic Surgery, Korea University, College of Medicine, Korea University Ansan Hospital 123, Jeokgeum-ro, Danwon- gu, Ansan-si, Gyeonggi-do, 15355, Korea e Department of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #80, Guro-dong, Guro-gu, Seoul 08308, Korea f Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-dong, Jeongeup-si, Jeollabuk-do 56212, Republic of Korea g Department of Systems Biotechnology, Chung-Ang University, Anseong, Gyeonggi 17546, Korea 1
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ars.els-cdn.com · Web vieweDepartment of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #80, Guro-dong, Guro-gu, Seoul 08308, Korea fAdvanced Radiation
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Supplementary Information
Enhanced tendon restoration effects of anti-inflammatory lactoferrin-immobilized
heparin-polymeric nanoparticles on Achilles tendinitis rat model
Hong Joon Choia,b,1, Somang Choic,1, Jae Gyoon Kimd,1, Mi Hyun Songe, Kyu-Sik Shime,
aDepartment of Orthopedic Surgery, College of Medicine Korea University, Anam-dong, Seongbuk-
gu, Seoul 02841, KoreabYonsei gunwoo Hospital, #1814, Nambusunhwan-ro, Gwanak-gu, Seoul 08787, Korea cDepartment of Biomedical Science, College of Medicine Korea University, Anam-dong, Seongbuk-
gu, Seoul 02841, KoreadDepartment of Orthopedic Surgery, Korea University, College of Medicine, Korea University Ansan
Hospital 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, KoreaeDepartment of Orthopedic Surgery and Rare Diseases Institute, Korea University Guro Hospital, #80,
Guro-dong, Guro-gu, Seoul 08308, KoreafAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, 1266 Sinjeong-
dong, Jeongeup-si, Jeollabuk-do 56212, Republic of KoreagDepartment of Systems Biotechnology, Chung-Ang University, Anseong, Gyeonggi 17546, Korea
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Materials
PLGA (50:50; Resomer RG505) was supplied by Boehringer Ingelheim (Ingelheim,