1 High-containment Laboratory Design & Construction Part Two – Architectural Detailing and Construction Issues Presented by: Gary Zackowitz, R.A. Harvard School of Public Health Center for Continuing Professional Education July 14 - 25, 2008 Boston, Massachusetts Goals of This Course Understanding Containment The “containment barrier” Bio-safety Level comparison Components, Details, Systems Methods and materials Focus Issues Renovation for Containment Challenges in developing countries Maintaining Construction Quality Architectural Detailing and Architectural Detailing and Construction Issues Construction Issues
42
Embed
Architectural Detailing and Construction Issues · 1 High-containment Laboratory Design & Construction Part Two – Architectural Detailing and Construction Issues Presented by: Gary
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
1
High-containment LaboratoryDesign & Construction
Part Two – Architectural Detailing and Construction Issues
Presented by:Gary Zackowitz, R.A.
Harvard School of Public Health Center for Continuing Professional EducationJuly 14 - 25, 2008 Boston, Massachusetts
Goals of This Course
Understanding Containment The “containment barrier”
Bio-safety Level comparison
Components, Details, SystemsMethods and materials
Focus IssuesRenovation for Containment
Challenges in developing countries
Maintaining Construction Quality
Architectural Detailing and Architectural Detailing and Construction IssuesConstruction Issues
2
Goals of This CourseUnderstanding Major Components
Be able to make reasonable choices
Recognize good (and bad) work
Identify Potential Issues
Be an active member of the “Team”
Architectural Detailing and Architectural Detailing and Construction IssuesConstruction Issues
BMBL a. Laboratory Personnel must be able to verify directional air flow. A visual monitoring device which confirms directional air flow must be provided at the laboratory entry. Audible alarms should be considered to notify personnel of air flow disruption.
Monolithic (including base)Resistance to disinfectantsEpoxy resin systems (ABSL-3)Seamless vinyl systems (BSL-3/BSL-2)Slip resistanceSubstrate preparationMoisture testing and waterproof coatings
BSLBSL--3 / ABSL3 / ABSL--3 Floors3 Floors
Base Detailing
11
BSLBSL--3 / ABSL3 / ABSL--3 Doors, Windows & Hardware3 Doors, Windows & Hardware
Stainless steel or FRP construction (ABSL-3)
Hollow Metal Seamless construction
Grouted frames (in CMU)
Tight-fitting
Electronic hardware provisions
Sealed windows
BSLBSL--3 / ABSL3 / ABSL--3 Doors, Windows & Hardware3 Doors, Windows & Hardware
Details
12
BSLBSL--3 / ABSL3 / ABSL--3 Doors, Windows & Hardware3 Doors, Windows & Hardware
BSLBSL-- 4 / ABSL4 / ABSL-- 4 Special Features4 Special Features
Chemical decontamination showers
BSLBSL-- 4 / ABSL4 / ABSL-- 4 Special Features4 Special Features
29
Effluent decontamination systems
Double walled containment pipe
BSLBSL-- 4 / ABSL4 / ABSL-- 4 Special Features4 Special Features
Focus IssuesFocus Issues
-- Renovation for ContainmentRenovation for Containment
-- Challenges in Developing CountriesChallenges in Developing Countries
-- Maintaining Construction QualityMaintaining Construction Quality
30
Renovation For ContainmentRenovation For Containment
How does it compare to new construction
Client expectations = new constructionDesign criteria = new constructionBiosafety criteria = new constructionSecurity requirements = new constructionDesign objectives = new constructionSF costs often > new constructionConstraints often > new construction
Renovation For ContainmentRenovation For Containment
Part Two – Architectural Detailing and Construction
Questions?Questions?
42
AcknowledgementsAcknowledgements
Thanks to Thanks to Uri Yokel, Uri Yokel, R.A. with LSY Architects for contributing R.A. with LSY Architects for contributing material and support for this lecture.material and support for this lecture.