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Psychophysiology of Stress and RelaxationPsychophysiology of Stress and Relaxation
By: Dr. Ernesto Sh. Korenman, MayBy: Dr. Ernesto Sh. Korenman, May 20092009
Take it easy.Take it easy.
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Various studies show thatVarious studies show that 6565%%--8080%%of all doctor visits have stress as aof all doctor visits have stress as asignificant componentsignificant component
heart diseaseheart disease
chronic fatiguechronic fatigue
anxiety attacksanxiety attacks
mood swingsmood swings
psychologicalpsychologicaldistressdistress
depressiondepressionsleep problemssleep problems
fluflu
virusesviruses
headachesheadaches
migrainesmigraines
alcoholismalcoholismsmokingsmoking--relatedrelated
respiratory alimentsrespiratory aliments
high bloodhigh blood
pressurepressure
eating disorderseating disorderspeptic ulcerspeptic ulcers
poor immunepoor immunefunctionfunction
chronic painchronic paincoldscolds
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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PerceptionPerception
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AwarenessAwareness
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ExpectationExpectation
What is Stress?What is Stress?6
A negative emotional experienceA negative emotional experience
accompanied by predictable:accompanied by predictable:
biochemical,biochemical,physiological,physiological,cognitive, andcognitive, and
behavioral changesbehavioral changes
that are directed either towardsthat are directed either towardsaltering the stressful event oraltering the stressful event or
accommodating to its effects.accommodating to its effects.Baum,Baum, 19901990
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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What is Stress?What is Stress?7
1.1. Emotional aspectEmotional aspect
2.2. Physiological aspectPhysiological aspect
3.3. BehaviouralBehavioural aspectaspect
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Sources of StressSources of Stress
PhysicalPhysical Actual physical illActual physical ill--health or harmhealth or harm
PsychologicalPsychological Anticipation of physical harmAnticipation of physical harm
Anticipation of damage to selfAnticipation of damage to self--esteem,esteem,social standing, important relationshipssocial standing, important relationships
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Stress responseStress response Aversive stimuli can elicit emotionalAversive stimuli can elicit emotional
responses:responses: Behavioral component: Fight or FlightBehavioral component: Fight or Flight
responseresponse
Autonomic component: SympatheticAutonomic component: Sympatheticactivationactivation
Endocrine component: secretion ofEndocrine component: secretion ofepinephrine, NEepinephrine, NE
Level of Stress is determined by personLevel of Stress is determined by person--environment fit:environment fit:
Depends upon how an event is appraised, and whether theDepends upon how an event is appraised, and whether the
person perceives themselves as possessing the resourcesperson perceives themselves as possessing the resourcesneeded to respond to the event successfully.needed to respond to the event successfully.
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Parts of the Nervous SystemParts of the Nervous System
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Parts of Nervous SystemParts of Nervous System
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Parts of Nervous SystemParts of Nervous System
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Autonomous Nervous SystemAutonomous Nervous System
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The Autonomic Nervous SystemThe Autonomic Nervous System
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Rest & DigestRest & Digest Fight or FlightFight or Flight
Resting HomeostasisResting Homeostasis Stress ResponderStress Responder
BrakesBrakes AcceleratorAccelerator
Point to pointPoint to point Systemic Fire AlarmSystemic Fire Alarm
ParasympatheticParasympathetic SympatheticSympathetic
Autonomic Nervous System BranchesAutonomic Nervous System Branches
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The Autonomic Nervous SystemThe Autonomic Nervous System
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The Autonomic Nervous SystemThe Autonomic Nervous System
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The Autonomic Nervous SystemThe Autonomic Nervous System
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The Autonomic Nervous SystemThe Autonomic Nervous System
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Central Autonomic CentersCentral Autonomic Centers
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HypothalamusHypothalamus
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HypothalamusHypothalamus
Blood PressureBlood Pressure
WaterWater balancebalance
ShiveringShivering
FeedingFeeding
SatietySatiety
Body TemperatureBody Temperature
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Autonomic neural pathwaysAutonomic neural pathways
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Visceral ReflexVisceral Reflex
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HomeostasisHomeostasis
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Physiology of Stress ResponsePhysiology of Stress Response
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ThalamusThalamusCortexCortex
HyppocampusHyppocampus
MedullaMedullaCerebellumCerebellum
HypothalamusHypothalamus
AmygdalaAmygdala
Emotional BrainEmotional Brain
1122
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The Brain and the Stress ResponseThe Brain and the Stress Response1.1. AAsensory nervesensory nerve registers aregisters a
stressful message.stressful message.
2.2. The message arrives to thalamusThe message arrives to thalamusand from there to the cortex (forand from there to the cortex (for
mental processing) and to themental processing) and to thelimbic systemlimbic system (for emotional(for emotionalassessment)assessment)..
3.3. TheThe thalamusthalamus then stimulates thethen stimulates thehypothalamus.hypothalamus.
4.4. TheThe hypothalamus,hypothalamus, in turn,in turn,activates theactivates the endocrine systemendocrine systemand theand the sympathetic nervoussympathetic nervoussystem.system. This action is what initiatesThis action is what initiatesthe stress reactivity.the stress reactivity.
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Stress ResponseStress Response
11 22
HYPAC axisHYPAC axis SAM systemSAM system
aa
bb
cc
bb
aa
cc
30
11
22
aa
bb
cc
aa
bb
cc
Stress ResponseStress Response
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Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
1.1. HYPACHYPAC activation ofactivation of
leading to release ofleading to release of
stress hormonesstress hormones
((cortisolcortisol))
2.2. SAMSAM activation whichactivation which
increases release ofincreases release of
norepinephrinenorepinephrine andand
epinephrineepinephrine
Physiology of Stress ResponsePhysiology of Stress Response
Triune Autonomic Nervous System Triune Autonomic Nervous System by Johnby John ChittyChitty
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Parasympathetic :Parasympathetic : TheThe PolyvagalPolyvagal TheoryTheoryTwo branches of theTwo branches of the vagusvagus forfor
different adaptive behavioraldifferent adaptive behavioral
strategies (facial expression,strategies (facial expression,
vocalization, listening, muscularvocalization, listening, muscular
posture)posture)
Mobilization systemMobilization system: promotes calm: promotes calmbehavioral states by inhibiting thebehavioral states by inhibiting the
sympathetic (fightsympathetic (fight--flight), Based onflight), Based on
modern mammalmodern mammal myelinatedmyelinated fibers.fibers.
Immobilization systemImmobilization system that producethat produce
a behavioral shut down (e.g.,a behavioral shut down (e.g.,
feigning death,feigning death, vasovaso--vagalvagal syncope,syncope,
etc. Based onetc. Based on phylophylo--geneticallygeneticallyprimitive system (primitive system (unmyelinatedunmyelinated
fibersorfibersor as in other vertebrates.as in other vertebrates.
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Short term effects of StressShort term effects of Stress
Release ofRelease of CatecholaminesCatecholamines::
Increase cardiovascular responseIncrease cardiovascular response
Increase respirationIncrease respiration
Increase perspirationIncrease perspiration
Release of Corticosteroids:Release of Corticosteroids:
Increase access to energy storageIncrease access to energy storage Increase of Protein and Fat mobilizationIncrease of Protein and Fat mobilization Decrease inflammationDecrease inflammation
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Long term effects of chronic stressLong term effects of chronic stress
Adrenal exhaustionAdrenal exhaustion
High blood pressure (High blood pressure (----> stroke, heart attacks)> stroke, heart attacks)
Loss of neurons in brain (e.g.Loss of neurons in brain (e.g. hippocampalhippocampal fieldfieldCACA11))
Suppression of the immune system (Suppression of the immune system (----> illness)> illness)
Suppression of the inflammatory system (delaysSuppression of the inflammatory system (delayshealing)healing)
Prolonged excess glucose availabilityProlonged excess glucose availability ----> diabetes> diabetes
(dysfunction in normal regulatory(dysfunction in normal regulatorymechanisms for stress)mechanisms for stress)
Panic disorderPanic disorder
Obsessive Compulsive DisorderObsessive Compulsive Disorder
Post traumatic stress disorderPost traumatic stress disorder
PhobiasPhobias
Generalized Anxiety DisorderGeneralized Anxiety Disorder
Collectively, effectCollectively, effect 1010--1515% of population.% of population.
Anxiety DisordersAnxiety Disorders
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Courtesy of the Erikson Institut e, ChicagoStress can be studied byStress can be studied by
measuring the stressmeasuring the stress
hormonehormone cortisolcortisol
Cortisone can be measured inCortisone can be measured insmall samples of childrenssmall samples of childrens
salivasaliva
Children dip cottonChildren dip cotton
dental rolls in a fewdental rolls in a few
grains of sweet crystalsgrains of sweet crystals
and lick off the sweet tasteand lick off the sweet taste
Like dip stick candyLike dip stick candy
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Coping Babysitters Who were:Coping Babysitters Who were:
Sensitive and ResponsiveSensitive and Responsive Cold and DistantCold and Distant
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008
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Sensitive/Response Care bySensitive/Response Care by BabysittersBabysitters BuffersBuffers
Stress Hormones inStress Hormones in 99--monthmonth--oldsolds
-0.1
-0.05
0
0.05
0.1
0.15
0.2
0.25
Sensitive/Responsive CareSensitive/Responsive CareHigh LowHigh Low
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The EndThe End
Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008