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AR 2009 Psycho Physiology of Stress SYMP- PARASYMP

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  • 8/2/2019 AR 2009 Psycho Physiology of Stress SYMP- PARASYMP

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    Psychophysiology of Stress and RelaxationPsychophysiology of Stress and Relaxation

    By: Dr. Ernesto Sh. Korenman, MayBy: Dr. Ernesto Sh. Korenman, May 20092009

    Take it easy.Take it easy.

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    2

    Various studies show thatVarious studies show that 6565%%--8080%%of all doctor visits have stress as aof all doctor visits have stress as asignificant componentsignificant component

    heart diseaseheart disease

    chronic fatiguechronic fatigue

    anxiety attacksanxiety attacks

    mood swingsmood swings

    psychologicalpsychologicaldistressdistress

    depressiondepressionsleep problemssleep problems

    fluflu

    virusesviruses

    headachesheadaches

    migrainesmigraines

    alcoholismalcoholismsmokingsmoking--relatedrelated

    respiratory alimentsrespiratory aliments

    high bloodhigh blood

    pressurepressure

    eating disorderseating disorderspeptic ulcerspeptic ulcers

    poor immunepoor immunefunctionfunction

    chronic painchronic paincoldscolds

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    3

    PerceptionPerception

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    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    AwarenessAwareness

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    5

    ExpectationExpectation

    What is Stress?What is Stress?6

    A negative emotional experienceA negative emotional experience

    accompanied by predictable:accompanied by predictable:

    biochemical,biochemical,physiological,physiological,cognitive, andcognitive, and

    behavioral changesbehavioral changes

    that are directed either towardsthat are directed either towardsaltering the stressful event oraltering the stressful event or

    accommodating to its effects.accommodating to its effects.Baum,Baum, 19901990

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    What is Stress?What is Stress?7

    1.1. Emotional aspectEmotional aspect

    2.2. Physiological aspectPhysiological aspect

    3.3. BehaviouralBehavioural aspectaspect

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    8

    Sources of StressSources of Stress

    PhysicalPhysical Actual physical illActual physical ill--health or harmhealth or harm

    PsychologicalPsychological Anticipation of physical harmAnticipation of physical harm

    Anticipation of damage to selfAnticipation of damage to self--esteem,esteem,social standing, important relationshipssocial standing, important relationships

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    9

    Stress responseStress response Aversive stimuli can elicit emotionalAversive stimuli can elicit emotional

    responses:responses: Behavioral component: Fight or FlightBehavioral component: Fight or Flight

    responseresponse

    Autonomic component: SympatheticAutonomic component: Sympatheticactivationactivation

    Endocrine component: secretion ofEndocrine component: secretion ofepinephrine, NEepinephrine, NE

    Level of Stress is determined by personLevel of Stress is determined by person--environment fit:environment fit:

    Depends upon how an event is appraised, and whether theDepends upon how an event is appraised, and whether the

    person perceives themselves as possessing the resourcesperson perceives themselves as possessing the resourcesneeded to respond to the event successfully.needed to respond to the event successfully.

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Parts of the Nervous SystemParts of the Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    11

    Parts of Nervous SystemParts of Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    12

    Parts of Nervous SystemParts of Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Autonomous Nervous SystemAutonomous Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    14

    The Autonomic Nervous SystemThe Autonomic Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Rest & DigestRest & Digest Fight or FlightFight or Flight

    Resting HomeostasisResting Homeostasis Stress ResponderStress Responder

    BrakesBrakes AcceleratorAccelerator

    Point to pointPoint to point Systemic Fire AlarmSystemic Fire Alarm

    ParasympatheticParasympathetic SympatheticSympathetic

    Autonomic Nervous System BranchesAutonomic Nervous System Branches

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    The Autonomic Nervous SystemThe Autonomic Nervous System

    17

    The Autonomic Nervous SystemThe Autonomic Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    18

    The Autonomic Nervous SystemThe Autonomic Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    The Autonomic Nervous SystemThe Autonomic Nervous System

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    20

    Central Autonomic CentersCentral Autonomic Centers

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    HypothalamusHypothalamus

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    HypothalamusHypothalamus

    Blood PressureBlood Pressure

    WaterWater balancebalance

    ShiveringShivering

    FeedingFeeding

    SatietySatiety

    Body TemperatureBody Temperature

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Autonomic neural pathwaysAutonomic neural pathways

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Visceral ReflexVisceral Reflex

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    HomeostasisHomeostasis

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Physiology of Stress ResponsePhysiology of Stress Response

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    27

    ThalamusThalamusCortexCortex

    HyppocampusHyppocampus

    MedullaMedullaCerebellumCerebellum

    HypothalamusHypothalamus

    AmygdalaAmygdala

    Emotional BrainEmotional Brain

    1122

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    The Brain and the Stress ResponseThe Brain and the Stress Response1.1. AAsensory nervesensory nerve registers aregisters a

    stressful message.stressful message.

    2.2. The message arrives to thalamusThe message arrives to thalamusand from there to the cortex (forand from there to the cortex (for

    mental processing) and to themental processing) and to thelimbic systemlimbic system (for emotional(for emotionalassessment)assessment)..

    3.3. TheThe thalamusthalamus then stimulates thethen stimulates thehypothalamus.hypothalamus.

    4.4. TheThe hypothalamus,hypothalamus, in turn,in turn,activates theactivates the endocrine systemendocrine systemand theand the sympathetic nervoussympathetic nervoussystem.system. This action is what initiatesThis action is what initiatesthe stress reactivity.the stress reactivity.

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    29

    Stress ResponseStress Response

    11 22

    HYPAC axisHYPAC axis SAM systemSAM system

    aa

    bb

    cc

    bb

    aa

    cc

    30

    11

    22

    aa

    bb

    cc

    aa

    bb

    cc

    Stress ResponseStress Response

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    1.1. HYPACHYPAC activation ofactivation of

    leading to release ofleading to release of

    stress hormonesstress hormones

    ((cortisolcortisol))

    2.2. SAMSAM activation whichactivation which

    increases release ofincreases release of

    norepinephrinenorepinephrine andand

    epinephrineepinephrine

    Physiology of Stress ResponsePhysiology of Stress Response

    Triune Autonomic Nervous System Triune Autonomic Nervous System by Johnby John ChittyChitty

    32

    Parasympathetic :Parasympathetic : TheThe PolyvagalPolyvagal TheoryTheoryTwo branches of theTwo branches of the vagusvagus forfor

    different adaptive behavioraldifferent adaptive behavioral

    strategies (facial expression,strategies (facial expression,

    vocalization, listening, muscularvocalization, listening, muscular

    posture)posture)

    Mobilization systemMobilization system: promotes calm: promotes calmbehavioral states by inhibiting thebehavioral states by inhibiting the

    sympathetic (fightsympathetic (fight--flight), Based onflight), Based on

    modern mammalmodern mammal myelinatedmyelinated fibers.fibers.

    Immobilization systemImmobilization system that producethat produce

    a behavioral shut down (e.g.,a behavioral shut down (e.g.,

    feigning death,feigning death, vasovaso--vagalvagal syncope,syncope,

    etc. Based onetc. Based on phylophylo--geneticallygeneticallyprimitive system (primitive system (unmyelinatedunmyelinated

    fibersorfibersor as in other vertebrates.as in other vertebrates.

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    33

    Short term effects of StressShort term effects of Stress

    Release ofRelease of CatecholaminesCatecholamines::

    Increase cardiovascular responseIncrease cardiovascular response

    Increase respirationIncrease respiration

    Increase perspirationIncrease perspiration

    Release of Corticosteroids:Release of Corticosteroids:

    Increase access to energy storageIncrease access to energy storage Increase of Protein and Fat mobilizationIncrease of Protein and Fat mobilization Decrease inflammationDecrease inflammation

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    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Long term effects of chronic stressLong term effects of chronic stress

    Adrenal exhaustionAdrenal exhaustion

    High blood pressure (High blood pressure (----> stroke, heart attacks)> stroke, heart attacks)

    Loss of neurons in brain (e.g.Loss of neurons in brain (e.g. hippocampalhippocampal fieldfieldCACA11))

    Suppression of the immune system (Suppression of the immune system (----> illness)> illness)

    Suppression of the inflammatory system (delaysSuppression of the inflammatory system (delayshealing)healing)

    Prolonged excess glucose availabilityProlonged excess glucose availability ----> diabetes> diabetes

    (dysfunction in normal regulatory(dysfunction in normal regulatorymechanisms for stress)mechanisms for stress)

    Panic disorderPanic disorder

    Obsessive Compulsive DisorderObsessive Compulsive Disorder

    Post traumatic stress disorderPost traumatic stress disorder

    PhobiasPhobias

    Generalized Anxiety DisorderGeneralized Anxiety Disorder

    Collectively, effectCollectively, effect 1010--1515% of population.% of population.

    Anxiety DisordersAnxiety Disorders

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

    36

    Courtesy of the Erikson Institut e, ChicagoStress can be studied byStress can be studied by

    measuring the stressmeasuring the stress

    hormonehormone cortisolcortisol

    Cortisone can be measured inCortisone can be measured insmall samples of childrenssmall samples of childrens

    salivasaliva

    Children dip cottonChildren dip cotton

    dental rolls in a fewdental rolls in a few

    grains of sweet crystalsgrains of sweet crystals

    and lick off the sweet tasteand lick off the sweet taste

    Like dip stick candyLike dip stick candy

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Coping Babysitters Who were:Coping Babysitters Who were:

    Sensitive and ResponsiveSensitive and Responsive Cold and DistantCold and Distant

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    Sensitive/Response Care bySensitive/Response Care by BabysittersBabysitters BuffersBuffers

    Stress Hormones inStress Hormones in 99--monthmonth--oldsolds

    -0.1

    -0.05

    0

    0.05

    0.1

    0.15

    0.2

    0.25

    Sensitive/Responsive CareSensitive/Responsive CareHigh LowHigh Low

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008

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    The EndThe End

    Dr. Ernesto Sh. Korenman,Dr. Ernesto Sh. Korenman, 20082008