Phospholipid Antibody Syndrome Myriad Presentation Dr.Anita Dr.K.S.V.Chalam,Dr.A.Lalitha,D r.A.P.Naveen Kumar,Dr.D.V.N.Sharma, Dr. M.K.Tripathy
Welcome message from author
This document is posted to help you gain knowledge. Please leave a comment to let me know what you think about it! Share it to your friends and learn new things together.
Transcript
APLA SYNDROME - Anti Phospholipid Antibody Syndrome
Myriad PresentationDr.Anita
Dr.K.S.V.Chalam,Dr.A.Lalitha,Dr.A.P.Naveen Kumar,Dr.D.V.N.Sharma, Dr. M.K.Tripathy
• Polyarthritis and rash• Gangrene of tips of fingers• Treated with LMWH and then acitrom• Recovered completely• ANA , DsDNA , Anti Cardiolipin positive• On follow up
• 28 yr. female• Recurrent abortions• Anti cardiolipin antibodies positive• Started on anticoagulants• Delivered a female baby with LMWH
ACA SYNDROME
• 34 yr. female• Polyarthritis and skin rash• Developed swelling of leg• Doppler showed DVT• ANA,DsDNA,Smith and Anti cardiolipin Ab.
positive
• Presented with septicemia and MODS• Recovered completely except for thrombocytopenia• ANA positive – treated with steroids• After 1 yr. developed swelling of abdomen• U/S s/o Budd Chiari• Investigations confirmed APLA
• 12 yr. girl• Recurrent abdominal pain• Confirmed as pancreatitis• Later symptoms of rash and arthritis• Investigations for SLE and APLA positive• On immunomodulants and acitrom• Developed CNS lupus and recovered
• Presented with convulsions• MRI brain – large bleed• Thrombocytopenia• MR Venogram – Sup. Saggital sinus thrombosis• APLA workup positive
Related Documents
