AP BIOLOGY DNA History & Structure
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AP BIOLOGYDNA History & Structure
Nucleic Acid Structure
Complimentary Base Pairing
Frederick Griffith
FREDERICK GRIFFITH EXPERIMENT
Living S cells(control)
Living R cells(control)
Heat-killedS cells (control)
Mixture of heat-killedS cells and livingR cells
Mouse dies
Living S cellsare found in blood sample
Mouse healthy Mouse healthy Mouse dies
RESULTS
Oswald Avery
Avery and group identified the transforming substance was DNA. His colleagues were McCarty and MacLeod.
Alfred Hershey & Martha Chase
Bacteriophage injecting its DNA into a bacterial cell
Electron Microscope View
Hershey – Chase Experiment
Erwin Chargaff
CHARGAFF’S RULE
Adenine = Thymine (DNA) or Uracil (RNA)&Guanine = CytosineIf you know the % composition of 1, you can find the % composition of the other 3.
Rosalind Franklin
DNA from a top view
DNA from a side view
James Watson & Francis Crick with their DNA model
See the HYDROGEN bonds?
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