central dogma -RNA chapter 7 central dogma • “central dogma of molecular biology” • originally coined by Francis Crick • not actually dogma • describes how DNA replicates and codes for proteins • protein coding • DNA unwinds • strands separate • transcription • translation amplification • transcription • many RNA copies can be made • translation • many polypeptide copies can be made from each mRNA transcription • initiation • strands separate • promoter region • elongation • RNA polymerase • termination
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“central dogma of molecular biology” central dogma -RNA · central dogma -RNA chapter 7 central dogma • “central dogma of molecular biology” • originally coined by Francis
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central dogma -RNA
chapter 7
central dogma• “central dogma of molecular biology”
• originally coined by Francis Crick• not actually dogma• describes how DNA replicates and codes for proteins
• protein coding• DNA unwinds
• strands separate• transcription• translation
amplification• transcription
• many RNA copies can be made• translation
• many polypeptide copies can be made from each mRNA
transcription• initiation
• strands separate• promoter region
• elongation• RNA polymerase
• termination
transcription• initiation
• strands separate• promoter region
• elongation• RNA polymerase
• termination
incoming nucleoside triphosphates
pre-mRNA transcript
RNA POLYMERASE
5’ 5’
3’
5’ 3’
eukaryotic transcription• more complex than prokaryotes
• 3 different polymerases• require general transcription factors• genes spread out along DNA