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Antepartum Haemorrhage Antepartum Hemorrhage
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Ante Partum

Mar 06, 2016

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Baso Agusofyang

Pendarahan Ante partum
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Antepartum Haemorrhage

Antepartum Hemorrhage

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Antepartum Haemorrhage

Objectives

• Definitions and Incidence

• Etiology and Risk Factors

• Diagnosis

• Management

- maternal and fetal assessment

- appropriate resuscitation- no vaginal exam prior to determining

 placental location

• Individual Causes

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Antepartum Haemorrhage

Definition

• vaginal bleeding between 20 weeks and delivery

Incidence

• 2% to 5% of all pregnancies• various causes of antepartum haemorrhage

- abruptio placenta 40% - 1% of pregnancie

- unclassified 35%

- placenta previa 20% - ½% of pregnancie

- lower genital tract lesion 5%- other 

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Antepartum Haemorrhage

Etiology of APH

• Cervical – contact bleeding (e.g. intercourse, pap, neoplasia, examination

 – inflammation (e.g. infection)

 – effacement and dilatation (e.g. labour, cervical incompetence

• Placental – abruptio

 – previa – marginal sinus rupture

• Vasa previa

• Other - abnormal coagulation

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Antepartum Haemorrhage

Diagnostic Procedures

• History and physical - No digital pelvic exam• Ultrasound 

 – definitive test for previa

 – less useful in abruptio

• Electronic Fetal Monitoring

 – for fetal compromise and uterine tone• Speculum

 – do ultrasound first if possible

 – No digital pelvic exam

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Antepartum Haemorrhage

Keep your bloody fingers

off the cervix!

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Antepartum Haemorrhage

Laboratory

• CBC, blood type, Rh, Coombs• coagulation status

 – INR, PTT, fibrinogen or TCT

• 2-4 units of PRBC cross matched as appropriate

• bedside clot test

• Kleihauer-Betke or Neirhaus test

 – vaginal and/or maternal blood 

• fetal lung maturity indices if appropriate

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Antepartum Haemorrhage

Hemodynamic Resuscitation

Risk Factors Tests (No vaginal exam)

Fetal / Maternal Assessment

Mother or fetus unstable Mother and fetus stable

Labs / Fetal Monitoring

U/S ± vaginal exam

Delivery

Vaginal Bleeding

Mother or fetus unstableExpectant

consider ongoing loss, etiology, gestation

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Antepartum Haemorrhage

Management - ABC ’s

• talk to and observe mother and fetus

• large bore IV access

• crystalloid (N/S)

• CBC and coagulation status

• cross-match and type

• get HELP!

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Antepartum Haemorrhage

Hemodynamic Resuscitation

• early aggressive resuscitation to protect fetus and

maternal organs from hypoperfusion and to prevent DIC

• stabilize vital signs• large bore IV crystalloid infusion

• follow hemoglobin and coagulation status• oxygen consumption is up 20% in pregnancy

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Antepartum Haemorrhage

Fetal Considerations

• lateral position increases cardiac output up to 30%

• consider amniocentesis for lung indices

• external fetal and labor monitoring

• Kleihauer-Betke if suspected abruption

• post-trauma monitor at least 4 hours for evidence of

fetal insult, abruptio, fetal maternal transfusion

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Antepartum Haemorrhage

Abruptio Placenta Definition

• premature separation of normally implanted placenta

Abruptio Placenta Classification

• Total - fetal death• Partial - fetus may tolerate up to 30-50% abruption

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Antepartum Haemorrhage

Risk Factors for Abruption

• hypertension: gestational and pre-existing

• abdominal trauma

• cocaine or crack abuse

• previous abruption

• overdistended uterus – multiple gestation, polyhydramnios

• smoking, especially >1 pack/day

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Antepartum Haemorrhage

Clinical Presentation of Abruption

• vaginal bleeding usually painful, unremitting

• presence of risk factor 

• hemodynamic status may not correlate with

amount of vaginal blood loss - concealed abruptio

• may be evidence of fetal compromise

• uterus - tender, irritable, contracting or tetanic

• ultrasound rules out previa and may show clot

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Antepartum Haemorrhage

ABRUPTION

Live Fetus Dead Fetus± coagulopathy

Delivery

(watch for DIC)

Assess Maturity

Maturity Immaturity

Vaginal delivery or C/S Steroids plus expectancy

Transfusion? Transfer?

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Antepartum Haemorrhage

Placenta Previa Definition

• placenta covers or lies near the cervix

Placenta Previa Classification

• total - entirely covers the os

• partial - partially covers the os

• marginal - close enough to the os to increase riskof bleeding as cervical effacement and 

dilatation occur 

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Antepartum Haemorrhage

Risk Factors for Previa

• previous placenta previa

• previous caesarean section or uterine surgery

• multiparity (5% in grand multiparous patients)

• advanced maternal age

• multiple gestation

• smoking

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Antepartum Haemorrhage

Clinical Presentation of Previa

• vaginal bleeding usually painless (unless in labour)

• maternal hemodynamic status corresponds to

amount of vaginal blood loss

• well tolerated by fetus unless maternal instability

• uterus - non-tender, not irritable, soft• may have abnormal lie

• ultrasound shows previa

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Antepartum Haemorrhage

PREVIA

Assess maturity

Maturity Immaturity

Delivery by C/S (consider accreta) Steroids plus expectancy

May try vaginal if marginal Transfusion? Transfer?

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Antepartum Haemorrhage

Vasa Previa Definition

• blood vessels in the membranes run across the cervix

• requires a vellamentous insertion or succenturiate lobe

Complication

• exsanguination following amniotomy or ROM

Diagnosis

• Apt test or Kleihauer test on vaginal blood • terminal fetal bradycardia ± initial tachycardia or sinusoidal F

Prognosis• fetal mortality as high as 50-70%

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