May 24, 2015
Topics
Transport systems functionally connect the organs of
exchange with the body cells
Most invertebrates have a gastrovascular cavity or a circulatory system for internal support
Vertebrate phylogeny reflected in adaptations of the
cardiovascular system
Topics
Double circulation in mammals depends on the anatomy and pumping cycle of the heart
Structural differences of arteries, veins and capillaries correlate with their different functions
Physical laws governing the movement of fluids through pipes affect blood flow and pressure
Topics
Transfer of substances between the blood and the interstitial fluid across the thin walls of capillaries
Components of blood Cardiovascular diseases are the
leading cause of death in the United States and other developed nations
Invertebrates circulatory system Gastrovascular cavity
Presence of 2-cell thick body wall Serves for digestion and circulation Both layers are bathed by fluid Inner layer- only exposed to food
Invertebrates circulatory system Planarians and other flatworms
Also have gastrovascular system Body shape ensures the efficient
transfer of food
Open vs Closed Circulatory System Gastrovascular cavity
Not suitable for animals with many cell layers
Open vs closed Overcomes the limits of diffusion Three basic components
Circulatory fluid (blood) Tubes (blood vessels) Pumping organ (heart)
Blood pressure- motive force for fluid movement
Open circulatory system
No distinction between blood and interstitial fluid hemolymph
Sinuses- interconnected spaces that surround organs
Heart contraction Pumps hemolymph
Heart relaxation Draws hemolymph through ostia
Closed Circulatory System Blood
Confined to vessels Blood is distinct from interstitial fluid
Movement of materials Larger vessels to smaller vessels Exchange of materials is through
diffusion
Vertebrate Phylogeny is reflected in adaptations of the cardiovascular system
• Cardiovascular system- presence of heart and vessels
• Atrium- receives blood• Ventricle- pumps blood• Vessels
• Arteries• Veins• Capillaries
Vertebrate Phylogeny Is Reflected in Adaptations of the Cardiovascular System
Venules Arterioles Capillary beds High metabolic rate- complex
cardiovascular system Low metabolic rate- less complex
Fish heart
Two main chambers Gill circulation Systemic circulation
Frogs and Other Amphibians Three-chambered heart Presence of forked artery
Pulmocutaneous circulation Systemic circulation
Double circulation- restores blood pressure
Mixing of blood Reptiles
Presence of ridge in the ventricle
Mammals, birds and crocodilians Four-chambered heart Left side- oxygen-rich Right side- oxygen poor No mixing of blood
Double Circulation in Mammals Depends on the Anatomy and Pumping Cycle of the Heart
The Human Heart
Cardiac cycle- complete pumping and filling
Systole- contraction Diastole- relaxation Cardiac output- vol of pumped blood
into systemic circuit per min Heart rate- no of beats per min Stroke volume- amount of blood pumped
per contraction
The Valves
Atrioventricular (AV) valve Close due to ventricular pressure
Semilunar valves Aorta Pulmonary artery Open due to ventricular pressure
Heart murmur- hissing sound Pulse- rhythmic stretching of arteries
The Valves
Lub dup sound Lub- recoil of blood against closed AV
valves Dup- recoil of blood against semilunar
valves
Maintaining the Heart’s Rhythmic Beat Heartbeat- maintained by specialized
heart cell Sinoatrial (SA) node- sets rhythmic
beat Also called the pacemaker Found in the wall of right atrium, superior
vena cava Atrioventricular (AV) node- relay point
Found bet right atrium and right ventricle Impulses are delayed at 0.1 s
Heart rate
Electrocardiogram (EKG or ECG) Record of impulse produced in the heart
Heart beat
P wave Atrial contraction
QRS complex Ventricular contraction
T wave Ventricularrecovery phase
Structural Differences of Blood Vessels Correlate with Their Different Functions
Capillaries- lack two outer layers Arteries- thicker outer layers than
veins Veins- presence of valves
Movement of Fluid Through Pipes Law of Continuity
Blood Pressure
Blood Pressure- highest in arteries during ventricular systole
Hydrostatic Pressure Peripheral Resistance
Impedance caused by arterioles
Blood pressure is influenced by different factors Nerves- slows, speed up Hormones Body temperature Exercise Gravity- large animals
Transfer of Substances through Capillaries Two mechanisms that control blood
flow Contraction of smooth muscle
Constricts the arteriole that decrease blood flow
Dilation increases blood flow Precapillary sphincters
Control blood flow
Capillary exchange
Takes place in the endothelial wall Maybe carried though bulk transport
(endocytosis and exocytosis) Diffusion (O2 and CO2) Diffusion or bulk flow through
intercellular clefts
Blood
Plasma Cellular component
RBC hemoglobin
WBC Platelets