ANEXO Depósito iPSC-CoQ4mut-clone 14 · para marcadores de pluripotencia. iPSC CQ4 C14 36% 33% 41% 40%. Ectodermo Endodermo iPSC CQ4 ...

g p py secuenciación

iPSC CQ4 C14

g p

iPSC CQ4 C14

iPS

CC

Q4

C14

DAPI/OCT4/SSEA-4

DAPI/NANOG/TRA-1-60

Oct4 Sox2 Rex1 Nanog CRIPTO DNMT3b0.00

0.05

0.10

0.15

0.20

hESCiPSC HDF C30iPSC CQ4 C14iPSC CQ4 C34

para marcadores de pluripotencia

iPSC CQ4 C14

36% 33% 41% 40%

Ectodermo Endodermo

iPSC

CQ4 C14

DAPI/NESTIN/TUJ1

Ectodermo Mesodermo Endodermo

iPSC

CQ4 C14

Nanog y Oct-4

β-Actin expression

iPSC HDF C30

iPSC CQ4 C34iPSC CQ4 C14

HDF SeV 7D

SeV expression

iPSC HDF C30

iPSC CQ4 C34iPSC CQ4 C14

HDF SeV 7D