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SPINAL CORD
PROF DR NASARUDDIN ABDUL AZIZ
Management & Science [email protected]
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OBJECTIVES
describe the external structure of the spinalcord,
draw and describe the internal structure of
the spinal cord,
draw and describe the ascending and
descending tracts within the spinal cord,
describe the meninges surrounding the
spinal cord,
describe the blood supply of the spinal cord,
explain the clinical correlations of &
applications related to the spinal cord
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Gross Appearance
Cylindrical in shape
Foramen magnum L1/L2 (adult)
L3 (newborn)
Occupies upper of vertebral canal
Surrounded by 3 layers of meniges:
dura mater
arachnoid mater
pia mater
CSF in subarachnoid space
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Enlargements: cervical & lumbar
Conus medullaris
Filum termniale Anterior median fissure
Posterior median sulcus
31 pairs of spinal nerves attached to it bythe anterior roots & posterior roots
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Structure Of The Spinal Cord
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Gray Matter
H-shaped pillar with anterior& posterior gray
horns
United by gray commissure containing the
central canal Lateral gray column (horn) present in
thoracic & upper lumbar segments
Amount of gray matter related to the amountof muscle innervated
Consists of nerve cells, neuroglia, blood
vessels
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Nerve cells in the anterior gray columns Large & multipolar
Axons pass out in the anterior nerve roots
as -efferents Smaller nerve cells are multipolar
Axons pass out in anterior roots as -
efferents
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Nerve cells in the posterior gray columns 4 nerve cell groups
Substantia gelatinosa
situated at the apex throughout the length of spinal cord
composed mainly ofGolgi Type II neurons
receives afferent fibres concerning with pain,
temperature & touch from posterior root
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Nucleus proprius anterior to substantia gelatinosa
present throughout the whole length of spinal
cord main bulk of cells in posterior gray column
receives fibers from posterior white column
that are assoc with proprioception, 2-point
discrimination & vibration
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Nucleus dorsalis (Clarks column)
base of posterior column C8 L3 / L4
associated with proprioceptive endings
(neuromuscular spindles & tendon spindles)
Visceral afferent nucleus
lateral to nucleus dorsalis
T1 L3
receives visceral afferent info
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Nerve cells in the lateral gray columns Formed by the intermediolateral group of
cells
T1 L2 / L3 Cells give rise to preganglionic
sympathetic fibres
In S2, S3, S4; they give rise topreganglionic parasympathetic fibres
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The gray commissure & central canal connects the gray on each side
central canal in the centre
posterior gray commissure
anterior gray commissure
central canal present throughout
superiorly continuous with the central canal ofmedulla oblongata
inferiorly, expands as terminal ventricle
terminates within the root of filum terminale
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White Matter
Divided into
anterior white column
lateral white column posterior white column
Consists of nerve fibres, neuroglia, blood
vessels
White due to myelinated fibres
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Tracts
Ascending
Descending
Intersegmental
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Ascending Tracts
Fibres that ascend from spinal cord to
higher centres
Conduct afferent information which may ormay not reach consciousness
Information may be
exteroceptive (pain, T, touch)
proprioceptive (from muscles & joints)
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Organization
Ascending pathway that reach
consciousness consists of 3 neurons:
1st-order neuron
2nd-order neuron
3rd-order neuron
Branch to reticular formation
(wakefulness)
Branch to motor neurons (reflex activity)
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Lateral spinothalamic tract pain & T
Anterior spinothalamic tract
light (crude) touch & pressure
Fasciculus cuneatus
Fasciculus gracilis
discriminatory touch, vibration, info from muscles &
joints Anterior spinocerebellar tract
Posterior spinocerebellar tract
unconscious info from muscles, joints, skin, subcut
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Spinotectal tract
spinovisual reflexes
Spinoreticular tract info from muscles, joints & skin to reticular
formation
Spino-olivary tract
indirect pathway to cerebellum
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Lateral spinothalamic tract
Pain & temp pathways
1st-order neurons
Pain conducted by A-type fibres & C-type
fibres
2nd-order neurons
decussate to the opposite side
ends in thalamus (ventral posterolateral nucleus 3rd-order neurons
ends in sensory area in postcentral gyrus
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Anterior spinothalamic tracts
Light (crude) touch & pressure pathways
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Posterior white column
Discriminative touch, vibratory sense,
conscious muscle joint sense (conscious
proprioception)
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Posterior spinocerebellar tract
Muscle joint sense pathways tocerebellum
Unconscious proprioception
Muscle joint info from muscle spindles,GTO, joint receptors of the trunk & lowerlimbs
Info is used by the cerebellum in thecoordination of movements & maintenanceof posture
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Anterior spinocerebellar tract
Majority of 2nd-order neurons cross to the
opposite side
Enter cerebellum through superiorcerebellar peduncle
Info from trunk, upper & lower limbs
Also carries info from skin & subcut tissue
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Descending Tracts
Lower motor neurons
Upper motor neurons
Corticospinal tracts concerned with voluntary, discrete, skilled
movements
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Reticulospinal tract facilitates or inhibits voluntary movement or reflex
activity
Tectospinal tract
reflex postural movements in response to visualstimuli
Rubrospinal tract
facilitates activity of flexor muscles & inhibitsactivity of extensor muscles
Vestibulospinal tract
facilitates extensor muscles, inhibits flexor
muscles
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Meninges
Dura mater
Arachnoid mater
Pia mater
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Dura mater
Dense, strong fibrous membrane
Encloses the spinal cord & cauda equina
Continuous above with meningeal layer ofdura covering the brain
Ends at the level of S2
Separated from wall of vertebral canal bythe extradural space
Contains loose areolar tissue & internal
vertebral venous space
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Arachnoid mater
Delicate impermeable membrane
Lies between pia and dura mater
Separated from pia mater by subarachnoidspace
Continuous above with arachnoid mater
covering the brain Ends on filum terminale at level of S2
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Pia mater
Vascular membrane
Closely covers spinal cord
Thickened on either side between nerveroots to form the ligamentum denticulatum
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Blood supply
Arteries of the spinal cord
Anterior spinal artery
Posterior spinal artery Segmental spinal arteries
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Anterior spinal artery
Formed by the union of 2 arteries
From vertebral artery
Supply anterior of spinal cord
Posterior spinal arteries
Arise from vertebral artery or posterior
inferior cerebellar arteries (PICA)
Descend close to the posterior roots
Supply posterior of spinal cord
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Segmental spinal arteries
Branches of arteries outside the vertebralcolumn
Gives off the anterior & posterior radicular
arteries Great anterior medullary artery of
Adamkiewicz
Arise from lateral intercostal artery or
lumbar artery at any level from T8 L3
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Clinical correlations
Spinal shock Follows acute severe damage to the spinal
cord
All cord functions below the level of thelesion become depressed or lost
Sensory impairment and flaccid paralysis
occur Segmental spinal reflexes are depressed
Persists for less than 24 hours (may be as
long as 1 4 weeks)
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Poliomyelitis Acute viral infection of the neurones of
anterior gray column
Motor nuclei of cranial nerves Death of motor neurone cells paralysis
& wasting of muscles
Muscles of lower limb more often affected
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