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3. INTRODUCTION:- 12 in number. Are part of the peripheral
nervous system All exit the cranial cavity through foramina or
fissures All originate from the brain except cranial nerve 11(
Accessory nerve) Contain sensory, motor or both components
4. ORIGIN:- The first and second cranial nerves derive from the
telencephalon and diencephalon respectively. olfactory nerve (CN I)
optic nerve (CN II) The third and fourth cranial nerves originate
from the midbrain. oculomotor nerve (CN III) trochlear nerve (CN
IV) The middle four cranial nerves originate from the pons
trigeminal nerve (CNV) abducens nerve (CNVI) facial nerve (CNVII)
vestibulocochlear nerve (CNVIII)
5. The final four cranial nerves originate from the medulla
oblongata glossopharyngeal nerve (CN IX) vagus nerve (CN X)
accessory nerve (CN XI) hypoglossal nerve (CN XII) In utero, 6
pharyngeal arches are designated but the 5th never develops. Each
pharyngeal arch is associated with a developing cranial nerve or
one of its branches. 1st arch-Trigeminal nerve(V3) 2nd arch- Facial
nerve 3rd arch- Glossopharyngeal nerve 4th arch- Superior Laryngeal
Branch ofVagus nerve 6th arch- Recurrent Laryngeal Branch ofVagus
nerve
6. Classification of cranial nerves Sensory cranial nerves:
contain only afferent (sensory) fibers Olfactory nerve Optic nerve
Vestibulocochlear nerve Motor cranial nerves: contain only efferent
(motor) fibers Oculomotor nerve Trochlear nerve Abducent nerve
Accessory nerv Hypoglossal nerve Mixed nerves: contain both sensory
and motor fibers--- Trigeminal nerve, Facial nerve,
Glossopharyngeal nerve Vagus nerve
7. Olfactory nerve-CN I Carries special afferents (SA) for
smell Peripheral processes act as receptors in the nasal mucosa
Receptors are located in the roof and upper parts of the nasal
cavity Central processes return information to the brain Central
processes enter cranial cavity through the Cribiform plate of the
ethmoid Terminate by synapsing with neurons in the olfactory bulb
Lesions result in ANOSMIA
9. Olfactory nerve. Axial (a) and coronal (b) 0.8-mm-thick SSFP
MR images show the olfactory nerve (white arrow) within the
CSF-filled olfactory groove . .
10. Olfactory nerve. Coronal 1.0-mm-thick SSFP MR image shows
the cisternal segment of the olfactory nerve (arrow), which is
located inferior to and between the gyrus rectus (r) and the medial
orbital gyrus (o).
11. Optic nerve-CN II Special afferents for vision Returns
information from photoreceptors in the retina to the brain Optic
nerve enter the cranial cavity through the optic canals Lesion
leads to blindness,visual field abnormalties and loss of light
reflex
12. Optic nerve. Axial oblique 0.8-mm-thick SSFP MR image shows
three of four segments of the optic nerve: the retinal (black
arrow), orbital (black arrowheads), and canalicular (white
arrowhead) segments. The infundibulum of the pituitary gland (white
arrow) also is seen
13. Oculomotor nerve- CN III Moves the eyeball in all
directions Adduction is the most important action Constricts pupil
(sphincter pupillae) Accomodates (ciliary muscle) Raises eyelids
(LPS) Carries 2 types of fibers GSE innervating most of the extra
ocular muscles (LPS,SR,IR,MR,IO) GVE part of the parasympathetic
part of Autonomic Nervous System -synapse in the ciliary ganglion
(pupillary constriction and accommodation) Exits the cranial cavity
via the lateral wall of the cavernous sinus through the superior
orbital fissure Lesion involves ptosis, external strabismus
etc
14. Oculomotor nerve. Axial oblique 0.8-mm-thick SSFP MR image
shows the nerve (small arrows) where it emerges from the
interpeduncular cistern (large arrow), which lies medial to the
cerebellar peduncle (p).
15. Oculomotor nerve. Coronal 0.8-mm-thick SSFP MR image shows
the oculomotor nerve (white arrow) in cross section between the
posterior cerebral artery (white arrowhead) and the superior
cerebellar artery (black arrowhead), which are distal branches of
the basilar artery (black arrow).
16. OCCULOMOTOR NERVE PALSY
17. Trochlear nerve CN IV GSE to Superior Oblique muscle Enters
the orbit via the lateral wall of the cavernous sinus Only cranial
nerve to exit from the posterior surface of the brainstem.
Inability to look inferiorly when the eye is adducted. Trochlear
nerve. Axial 0.8-mm-thick SSFP MR image shows both trochlear nerves
(arrows) where they emerge from the dorsal midbrain to cross the
ambient cisterns.The characteristic course of the trochlear nerves
allows their differentiation from the nearby superior cerebellar
artery (arrowheads).
18. Trigeminal nerve CNV Major general sensory nerve of the
head, motor innervation to muscles that move the lower jaw
GSA-sensory input from the face, the scalp, mucous membrane of oral
and nasal cavity ,PNS, part of theTM, eye and conjunctiva, dura
mater in the anterior and middle cranial fossa 2 roots- Large
sensory - small motor In middle cranial fossa sensory root expands
into theTrigeminal ganglion.(trigeminal depression) 3 divisions:-
V1- ophthalmic nerve V2- maxillary nerve V3- mandibular nerve
19. Trigeminal nerve. Axial 0.8-mm-thick SSFP MR image shows
the sensory (arrowhead) and motor (large arrow) roots of the
trigeminal nerve where they cross the prepontine cistern and enter
the Meckel cave (small arrows).
20. Ophthalmic nerve (V1) exits the cranial cavity into the
orbit via the lateral wall of the cavernous sinus and superior
orbital fissure Sensory from the eyes, conjunctiva and orbital
contents including the lacrimal gland Maxillary nerve(V2) Exits the
cranial through foramen rotundum Sensory branches from anterior and
middle cranial fossa, nasopharynx, palate, nasal cavity, teeth of
the upper jaw, maxillary sinus, skin of the side of the nose, lower
eyelid, cheek, upper lip Mandibular nerve(V3) Exits skull through
foramen ovale Motor root of CNS also exits through foramen ovale
and unites with the sensory component of V3 outside the skull Only
division that contains a motor component Motor fibers innervate
muscles of mastication, tensor tympani, anterior belly of
digastric
21. Sensory fibres from the skin of the lower face, cheek lower
lip, ear, external auditory meatus and temporal region, anterior
two thirds of the tongue, teeth of the lower jaw, mastoid air
cells, mucus membrane and dura in the middle cranial fossa Lesion
involves loss of sensation, weakness in chewing, Jaw deviation
towards the affected side, Trigeminal neuralgia Trigeminal nerve.
Coronal 0.8-mm-thick SSFP MR image at the level of the Meckel cave
shows the complex web of trigeminal nerve branches (arrows), which
coalesce anteriorly to form the gasserian ganglion.The temporal
horn of the lateral ventricle (arrowhead) is also shown.
22. Abducent nerve-CN VI GSE Lateral Rectus in orbit Crosses
the cavernous sinus as it enters the orbit through the superior
orbital fissure Lesion-internal strabismus
23. Abducens nerve. Axial 0.8-mm-thick SSFP MR image at the
level of the pontomedullary junction shows both abducens nerves
(arrows) where they traverse the prepontine cistern.The bottom of
the pons (p) and the top of the medulla (m) are visible in this
section, and the cerebellopontine angle (CPA) and basilar artery
(arrowhead) are important anatomic landmarks.
24. Abducens nerve. Axial 0.8-mm-thick SSFP MR image shows the
abducens nerve where it enters the Dorello canal (arrow) along the
posterior aspect of the clivus.Vascular landmarks include the
basilar artery (black arrowhead) and the anterior inferior
cerebellar artery (white arrowhead).
25. Facial nerve- CN VII Carries GSA,SA,GVE and BE GSA-sensory
input from external auditory meatus and small skin posterior to the
ear. SA-taste from anterior two thirds of the tongue
GVE-parasympathetic part of Autonomic Nervous System -stimulate
secretomotor activity in the lacrimal gland, submandibular and
sublingual glands, mucus membranes of the nasal cavity, hard and
soft palates BE-muscles of the face, scalp, stapedius, posterior
belly of the digastric and stylohyoid muscles 2 roots- Large motor
- Smaller sensory (the intermediate nerve)
26. Intermediate nerve contains SA (taste), GVE
(parasympathetic) and GSA Large motor root contains the BE fibres
Both roots exit the posterior cranial fossa through the internal
auditory meatus and fuse within the facial canal (petrous part of
the temporal bone) facial nerve Expands into the geniculate
ganglion Greater petrosal nerve preganglionic parasympathetic Nerve
to stapedius and chorda tympani in the facial canal Exits the
skulls through the stylomastoid foramen Chorda tympani carries
taste (SA) fibres from the anterior two thirds of the tongue and
preganglionic parasympathetic (GVE) to the submandibular
ganglion.
27. Axial 0.8-mm-thick SSFP MR image shows the parallel courses
of the facial (black arrowheads) and superior vestibular (white
arrowheads) nerves as they cross the cerebellopontine angle to
enter the internal auditory canal through the porus acusticus
(double arrow).
28. Vestibulocochlear nerve-CNVIII SA for hearing and balance 2
divisions -vestibular component for balance -cochlear component for
hearing
29. Glossopharyngeal nerve CN (IX) carries GVA, SA, GVE, and BE
fibers: GVA fibers provide sensory input from the carotid body and
sinus, posterior one-third of the tongue, palatine tonsils, upper
pharynx, and mucosa of the middle ear and pharyngotympanic tube; SA
fibers are for taste from the posterior one-third of the tongue;
GVE fibers are part of the parasympathetic part of the autonomic
division of the PNS and stimulate secretomotor activity in the
parotid salivary gland BE fibers innervate the muscle derived from
the third pharyngeal arch (the stylopharyngeus muscle)
30. Coronal oblique 0.8-mm-thick SSFP MR image through the
cerebellopontine angle shows the glossopharyngeal nerve (arrow)
just beneath the flocculus (f) of the cerebellum.The two roots of
the vagus nerve (arrowheads) are visible in the same plane, and the
superior and inferior vestibular nerves canbe seen above the
flocculus. Tympanic nerve: branch from CN IX within the jugular
foramen Forms part of the tympanic plexus within the middle ear
cavity Contributes GVE which leaves tympanic plexus in the lesser
petrosal nerve carrying preganlionic parasympathetic fibres to the
otic ganglion parotid
31. Vagus nerve- CN X carries GSA, GVA, SA, GVE, and BE fibers:
GSA fibers provide sensory input from the skin posterior to the ear
and the external acoustic meatus; GVA fibers provide sensory input
from the aortic body chemoreceptors and aortic arch baroreceptors,
and the mucous membranes of the pharynx, larynx, esophagus,
bronchi, lungs, heart, and abdominal viscera in the foregut and
midgut; SA fibers are for taste around the epiglottisGVE fibers are
part of the parasympathetic part of the autonomic division of the
PNS and stimulate smooth muscle and glands in the pharynx, larynx,
thoracic viscera, and abdominal viscera of the foregut and
midgut;
32. BE fibers innervate one muscle of the tongue
(palatoglossus), the muscles of the soft palate (except tensor veli
palatini), pharynx (except stylopharyngeus), and larynx. Lesion-
dysphagia, hoarseness, uvula points away from the affected side,
loss of gag and cough reflex, Horner's syndrome Axial oblique
0.8-mm-thick SSFP MR image shows the vagus nerve (arrow) where it
crosses the lateral cerebellomedullary cistern (LCM) and approaches
the jugular foramen.The vagus and glossopharyngeal nerves, which
are difficult to distinguish in this plane, are clearly
distinguishable in the coronal oblique plane
33. Accessory nerve-CN XI BE fibres to the sternocleidomastoid
and trapezius muscles Roots arise from the motor neurons in the
upper 5 segments of the cervical spinal cord Turns head to opposite
side/elevates and rotates scapula Lesion- shoulder droop, weakness
turning head to opposite side Axial 0.8 mm-thick SSFP MR image at
the level of the cervicomedullary junction (CMJ) shows the cranial
rootlets (arrowheads) of the accessory nerve
34. Hypoglossal nerve- CN XII GSE- Intrinsic and most extrinsic
muscles of the tongue Exits the cranial cavity through the
hypoglossal canal Supplies the hyoglossus, styloglossus,
genioglossus and all the extrinsic muscles of the tongue Lesion
causes tongue to point towards affected side Coronal oblique
0.8-mm-thick SSFP MR image shows multiple hypoglossal nerve roots
(arrows) converging toward the hypoglossal foramen (arrowhead).The
nerve roots are immediately posterior to the vertebral artery
(V).