Anatomy & Neurobiology ANA 812 Urinary System: Kidney, Ureter & Urinary Bladder Kelly Chewning Emily Furlow Phil Keeley Laura Ross.

Anatomy & Neurobiology

ANA 812Urinary System:

Kidney, Ureter & Urinary Bladder

Kelly ChewningEmily FurlowPhil KeeleyLaura Ross

Anatomy & Neurobiology

Slide #126 Kidney- Human (H&E) – 2X

Minor Calyces

Renal Papilla

Papillary Duct

Collecting Ducts

Anatomy & Neurobiology

Slide #126 Kidney- Human (H&E) – 4X

Medullary Rays

Cortex

Renal Corpuscles

Anatomy & Neurobiology

Slide #126 Kidney- Human (H&E) – 40X

Renal Corpuscle

Proximal Convoluted

Tubule

Distal Convoluted

Tubule

Macula Densa

PCT

DCT

Anatomy & Neurobiology

Slide #127 Kidney – Monkey (H&E) – 2X

Medulla

Cortex

Anatomy & Neurobiology

Slide #127 Kidney – Monkey (H&E) – 4X

Arcuate

artery

Interlobular artery

Cortex – Medullar

y Junction

Anatomy & Neurobiology

Slide #126 Kidney – Human (H&E) – 40X

Bowman’s

(Filtration) Space

Visceral Layer (Podocyte Layer)

Bowman’s Capsule = Visceral +

Parietal Layers

Parietal Layer

Vascular Pole Urinary

Pole

Anatomy & Neurobiology

Slide #126 Kidney – Human (H&E) – 40X

Extraglomerular

mesangial cells

Afferent Arteriol

e

Region of Juxtaglomeru

lar Cells

(line afferent arteriole)

Anatomy & Neurobiology

Slide #128 Kidney – Monkey (H&E) – 40X

Bowman’s (Filtration)

Space

Macula Densa

Basement Membrane

Anatomy & Neurobiology

Slide #127 Kidney – Monkey (H&E) – 60X

Thin Loop of Henle

Collecting Ducts

Anatomy & Neurobiology

Slide #126 Kidney – Human (H&E) – 4X/40X

Transitional epithelium

Anatomy & Neurobiology

Slide #126 Kidney – Human (H&E) – 10X/40X

Papillary Ducts

Simple columnar epithelium

Anatomy & Neurobiology

Slide #131 Ureter- Monkey (H&E) – 4X

Transitional epithelium

Lamina propria (fibroelastic CT)

Smooth Muscle

Adventitia (loose areolar CT)

Anatomy & Neurobiology

Slide # 131 Ureter- Monkey (H&E) – 10X

Smooth muscle:

Inner layer longitudinal

Outer layer circular

(reverse of GIT)

•No distinct submucosa present in any ureter.

•Mucosa forms longitudinal folds

Anatomy & Neurobiology

Slide #131 Ureter- Monkey (H&E) - 40X

Why ureter transitional epithelium is so special:

Its basal cells are columnar in shape, however…

Most superficial cells are large and broad with dome-shaped surface facing the lumen.

Anatomy & Neurobiology

Slide # 133 Urinary Bladder- Monkey (H&E) - 4X

Detrusor

Lamina propria (fibroelastic CT)

Transitional Epithelium

Adventitia (loose areolar CT) (except for fundus: serosa)

Anatomy & Neurobiology

Slide # 133 Urinary Bladder- Monkey (H&E) – 4X

Detrusor smooth muscle:

Outer longitudinal

Circular

Inner longitudinal

Anatomy & Neurobiology

Slide # 133 Urinary bladder- monkey (H&E) – 40X

Like the ureter- the Transitional Epithelium is unique:

Its basal cells are columnar in shape, however…

Most superficial cells are large and broad with dome-shaped surface facing the lumen.

Anatomy & Neurobiology

Slide # 133 Urinary Bladder- Monkey (H&E) – 10X

Bladder is empty- mucous lining in folds.

* The bladder has no distinct submucosa

Anatomy & Neurobiology

Slide # 132 Female Urethra- Monkey (H&E) - 4X

Adventitia (loose areolar CT)

Smooth muscleLamina propria (fibroelastic CT)

Epithelial lining

Anatomy & Neurobiology

Slide # 132 Female Urethra- Monkey (H&E) - 40 X

Transitional epithelium Pseudostratified columnar Stratified squamous epithelium