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ANALISA DATA DANPENYAJIAN

DR.dr Ika K Oktaviyanti,M.Kes,SpPA

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DATA Primer

Sekunder

Diambil sesuai dengan variabel yangdibutuhkan

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PenyajianDi paparkan agar menarik, dalam bentuk Tabel

diagram Gambar

Grafik

uraian

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Tabel 1.Faktor yang menyebabkan ekspresi VEGF (Dai & Rabie et al, 2007).

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Effects of indomethacin and rofecoxib

on the gastric mucosa of normal and H. pylori-infected

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Fig. 1. NO plasmaticlevel (NO, M). Measured as nitrite+nitrate in heparinized plasma. Statistical significance:

Group A vs. B, P

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Fig. 4. CD62P and I correlation in Group A. Pearson's r

(correlation coefficient)=.9521. R2=.9066. P

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Fig. 1. Comparison of the BAFMD results according to the clinical severity of the PAD.

*P

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Fig. 2.Gross appearances of the gastric mucosa in normal (A) and

H. pylori-infected M. gerbils (B), with and without indomethacin (2 mg/kg, s.c.) or

robecoxib (10 mg/kg, p.o.).

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Proposed mechanisms of VEGFNO relationship inactivation of angiogenic events in endothelial cells.Increased generation of NO by SMCs, obtainedeither by genetic augmentation (e.g. eNOS

transfection) or by induction of iNOS canenhance VEGF production in VSMCs. VEGFactivates its receptor(s) leading to the increasedeNOS activity and NO generation in ECs. Itremains to be elucidated whether NO exerts adirect pro-angiogenic effect in ECs, or whetherits activity is mediated by the autocrinestimulation of VEGF synthesis.

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Gambar 4. Signal aktivasi VEGF (Matsumoto, 2001)

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TARGETING ATHEROSCLEROSIS-ANEVIDENCE UPDATE

Supporting : Global Risk Reduction

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ATORVASTATIN SIGNIFICANTLY REDUCEDMMP 9 LEVELS IN A DOSE DEPENDENT MANNER

*P

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EFFECT OF ATORVASTATIN ON THE PRIMARY ENDPOINT: MAJOR CV EVENTS INCLUDING STROKE

Relative Risk Reduction 37% (95% CI: 17-52)

Years328305

694651

10741022

13611306

13921351

AtorvaPlacebo

14281410

Placebo

127 events

Atorvastatin

83 eventsCumulativehazard(%)

0

5

10

15

0 1 2 3 4 4.75

P=.001

Colhoun HM, Betteridge DJ, Durrington PN, et al. Lancet. 2004;364:685-696.

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ATHEROSCLEROSIS STARTS ATA YOUNG AGE

0%20%40%60%80%

100%

35Donor Age (yr)

22%

47%

70%

Nissen S. Am J Card io l .2001:87(suppl):15A-20A.

Determined by coronary intravascular ultrasound

Prevalenceo

f

A

therosclerosis

(%)

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CRP IS A PREDICTOR OF CARDIOVASCULAR DISEASE

Ridker PM. Circulation.2001;103:1813-1818; Libby P et al. Circulation. 2002;105:1135-1143.

1

2

3

4

5

1

2

3

4

5

1

2

3

4

5

6

7

8

9

8.7

7.2

6.0

6.0

5.1

4.2

3.0

2.2

1.7

2.5

3.5

4.2

2.9

2.1

1.4

5.0

3.5

2.5

1.7

1.2

1.0

1.4

2.0

2.9

4.2Relativerisk

. Circulation.2001;103:1813-1818; Libby P et al. Circulation. 2002;105:1135-1143

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Data yang dicantumkan hanyalahdata yg memberikan bukti terhadap

hipotesis atau menjawabpermasalahan.

Interpretasi data dikaitkan dengan

masalah, pertanyaan atau hipotesisyang disusun

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Penyajian data harus berurutan selarasdgn pengamatan / analisis yang ada padabagian Bahan dan Metode.

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