Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct by Uma Mahesh Gundra, Natasha.
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Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically
and functionally distinct
by Uma Mahesh Gundra, Natasha M. Girgis, Dominik Ruckerl, Stephen Jenkins, Lauren N. Ward, Zachary D. Kurtz, Kirsten E. Wiens, Mei San Tang, Upal Basu-Roy,
Gene expression profiling of monocyte-derived and tissue macrophage-derived AAMs. (A) Unsupervised hierarchical clustering of transcriptional profiles, displayed as a heat map of log-
transformed expression values, from FACS-purified (CD11b+F4/80+) macrophag...
GO analysis of transcriptional profiles from monocyte-derived and tissue resident macrophage-derived AAMs. (A) Biological processes (BPs) induced in IL-4c expanded AAM (IL-4c) relative to
resident macrophages (Res). x-axis indicates the amount of statistica...
AAMs derived from inflammatory monocytes express PD-L2, CD206, and MHC class II, but not tissue macrophage-derived AAMs. FACS analysis of (A) PD-L2, (B) CD206 and (C) MHC class II
from peritoneal macrophages of mice untreated (naïve/resident) or injected i....
Different helminth infections induce either monocyte-derived or tissue-derived AAMs. (A) Representative FACs plots of pleural cavity macrophages on day 12 after L sigmodontis
infection compared with pleural cavity macrophages of mice untreated (Res) or inje...
Ucp1 is a unique marker for tissue resident macrophage-derived AAMs. (A) Microarray data for Ucp1 from AAMs. (B) Real-time PCR measurement of Ucp1 expression (relative to GAPDH) in