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Launch of the Alexandrite Laser for the JOULE Sciton International March 17, 2010 © 2010 Sciton, Inc. All rights reserved. 1
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Alex launch presentation intl dist 0317

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Page 1: Alex launch presentation intl dist 0317

Launch of the Alexandrite Laser for

the JOULE

Sciton International March 17, 2010

© 2010 Sciton, Inc. All rights reserved.1

Page 2: Alex launch presentation intl dist 0317

Table of Contents

2 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 3: Alex launch presentation intl dist 0317

Introduction – Laser Hair Removal

• Epilation by laser was used experimentally for 20 years before it became commercially available in the mid 1990s.

• Soon laser hair removal became common, Food and Drug Administration (FDA) approved its use as "permanent hair reduction" in 1997.

• Laser and light-based hair reduction are now most commonly referred to collectively as "laser hair removal".

• Hair removal is commonly done on lip, chin, ear lobe, shoulders, back, underarm, abdomen, buttocks, pubic area, bikini lines, thighs, face, neck, cleavage, chest, arms, legs, hands, and toes.

• Laser works best with dark coarse hair. Light skin and dark hair are an ideal combination, but new lasers are now able to target dark black hair even in patients with dark skin.

3 © 2010 Sciton, Inc. All rights reserved.

Page 4: Alex launch presentation intl dist 0317

Technologies

• Several wavelengths of laser energy have been used for hair removal, from visible light to near-infrared radiation.

• According to the history of laser hair removal, these technologies were once used and some are still being used

• Argon: 488 or 514.5 nm (no longer used for hair removal)

• Ruby: 694 nm (no longer used for hair removal; some articles claimed that it is not safe on most skin types and caused pigmentation changes, especially on lighter skin type)

• Alexandrite: 755 nm (most effective and safest on light skin types)

• Pulsed diode array: 810 nm (for light to medium type skin)

• Nd:YAG: 1064 nm (for all six skin colors, even tanned skin)

4 © 2010 Sciton, Inc. All rights reserved.

Page 5: Alex launch presentation intl dist 0317

Table of Contents

5 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 6: Alex launch presentation intl dist 0317

Total Nonsurgical, Minimally-Invasive Aesthetic Procedures in the US: 2002 – 2008: Over 10 Million in 2008

6 © 2010 Sciton, Inc. All rights reserved.

Source: American Society for Aesthetic Plastic Surgery

Page 7: Alex launch presentation intl dist 0317

Laser Hair Removal - #2 for ALL Cosmetic Procedures (Including Surgical and Nonsurgical)

7 © 2010 Sciton, Inc. All rights reserved.

Source: ASAPS

Page 8: Alex launch presentation intl dist 0317

Laser Hair Removal Ranked as the Second Most Performed Nonsurgical Procedure in 2008 by ASAPS

8 © 2010 Sciton, Inc. All rights reserved.

Page 9: Alex launch presentation intl dist 0317

American Society of Plastic Surgeons Ranked LHR as the 4th Most Performed Minimally-Invasive Procedure in 2008

9 © 2010 Sciton, Inc. All rights reserved.

Laser hair removal remains, and is expected to remain, an extremely popular procedure!

Page 10: Alex launch presentation intl dist 0317

ASAPS and ASPS 2008 Rankings for LHR in Men and Women: LHR Is a Top Procedure for Both

Top 5 nonsurgical cosmetic procedures for women in 2008

1. Botox - 2,239,024

2. Hyaluronic acid - 1,200,420

3. Laser hair removal - 1,101,255

4. Chemical peel - 554,492

5. Laser skin resurfacing - 532,008

10 © 2010 Sciton, Inc. All rights reserved.

Top 5 nonsurgical cosmetic procedures for men in 2008

1. Botox injection - 255,099

2. Laser hair removal - 179,708

3. Hyaluronic acid - 62,428

4. IPL laser treatment - 46,887

5. Microdermabrasion - 39,824

Source: American Society for Aesthetic Plastic Surgery

Source: American Society of Plastic Surgeons

Page 11: Alex launch presentation intl dist 0317

ASAPS Estimates the Average Procedure Fee for LHR is $326

11 © 2010 Sciton, Inc. All rights reserved. Source: ASAPS

In 2008, ASAPS estimated the total US LHR market to be $417M

Page 12: Alex launch presentation intl dist 0317

The ASPS Estimated the Average Fee for LHR is $456

12 © 2010 Sciton, Inc. All rights reserved.

In 2008, ASPS estimated the total US LHR market to be $406M

The 2008 US LHR Market Was $406 - $417M

Page 13: Alex launch presentation intl dist 0317

13 © 2010 Sciton, Inc. All rights reserved.

How Big Is the Laser Market for Hair Removal?

Page 14: Alex launch presentation intl dist 0317

Medical Insight Estimated the 2008 Worldwide Laser and Light Aesthetic Devices Market to be $280M

Sciton estimates the worldwide 2009 laser & light hair removal market was$168M.

14 © 2010 Sciton, Inc. All rights reserved.

Source: Emerging Market for Aesthetic Technologies, Medical Insight, Sciton Est.

Source: Medical Insight, Sciton estimates.

Page 15: Alex launch presentation intl dist 0317

Table of Contents

15 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 16: Alex launch presentation intl dist 0317

Introducing ClearScan ALX

16 © 2010 Sciton, Inc. All rights reserved.

510K – FDA Cleared Indications for Use for 755 nm

The 755 nm is indicated for stable long-term, or permanent hair reduction for all skin types (Fitzpatrick I - VI) including tanned skin. It is also indicated for the treatment of vascular lesions, benign pigmented lesions and wrinkles.

Obtaining CE Mark and regulatory clearance worldwide is in progress.

Page 17: Alex launch presentation intl dist 0317

ClearScan ALX Specifications

17 © 2010 Sciton, Inc. All rights reserved.

Page 18: Alex launch presentation intl dist 0317

ClearScan ALX ConfigurationsConfigurations – New Systems

• ClearScan ALX Single Module• ClearScan ALX with ClearScan YAG, delivered separately• ClearScan ALX with ClearScan YAG, multiplexed

• Two Separate Scanners• Integrated Scanner: for 755 nm ClearScan ALX™ or lower fluence 1064 nm ClearScan YAG™ applications (6 mm spot)• HighFluence Integrated Scanner: for 1064 nm ClearScan YAG™ or 1319 nm ThermaScan™ applications (5 mm spot)

• 3 and 6 mm Single Spot Hand pieces

Upgrades: Upgrades will be available in June

18 © 2010 Sciton, Inc. All rights reserved.

Page 19: Alex launch presentation intl dist 0317

ClearScan ALX, Single Module

19 © 2010 Sciton, Inc. All rights reserved.

• Joule, Single-Laser Wavelength Modular Platform

• Arm Delivery

• Single 755 nm Module-Alexandrite Laser

• Integrated Scanner: for 755 nm ClearScan ALX™ or lower fluence 1064 nm ClearScan YAG™ applications (6 mm spot)

• 3 and 6 mm single spot handpiece

• 250 Watt Thermoelectric Cooling System

• 3 Goggles

Page 20: Alex launch presentation intl dist 0317

ClearScan ALX + ClearScan YAG

20 © 2010 Sciton, Inc. All rights reserved.

• Joule, Multi-Laser Wavelength Modular Platform

• Arm Delivery

• Single 755 nm Module: Alexandrite Laser• Single 1064 nm Module: Nd:YAG Laser

• Integrated Scanner: for 755 nm ClearScan ALX™ or lower fluence 1064 nm ClearScan YAG™ applications (6 mm spot)

• 3 and 6 mm single spot handpiece

• 250 Watt Thermoelectric Cooling System

• 3 Goggles

• OPTIONAL: HighFluence Integrated Scanner: for 1064 nm ClearScan YAG™ or 1319 nm ThermaScan™ applications (5 mm spot)

• OPTIONAL: MULTIPLEXING

Page 21: Alex launch presentation intl dist 0317

ClearScan ALX and ClearScan YAG User Interface

21 © 2010 Sciton, Inc. All rights reserved.

Page 22: Alex launch presentation intl dist 0317

Table of Contents

22 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 23: Alex launch presentation intl dist 0317

23 © 2010 Sciton, Inc. All rights reserved.

EFFECTIVE AND TRUSTED RESULTS

SUPERIOR COMFORT

FAST

EXPANDABLE PLATFORM

The New Era in Alexandrite Laser Hair Removal!

Page 24: Alex launch presentation intl dist 0317

24 © 2010 Sciton, Inc. All rights reserved.

Page 25: Alex launch presentation intl dist 0317

MYTH #1: A 6mm Spot Will Not Work

“But You Only Have a 7 mm Spot; This Will Not Work.”

Customers have been indoctrinated to believe that a large spot size is• Required to achieve efficacy

THIS IS NOT TRUE

• Necessary for fast treatmentTHIS IS NOT TRUE

25 © 2010 Sciton, Inc. All rights reserved.

Page 26: Alex launch presentation intl dist 0317

It’s The Energy at the Target That Makes a Difference

• Gaussian beam versus Top Hat

• Depth of Penetration

26 © 2010 Sciton, Inc. All rights reserved.

Page 27: Alex launch presentation intl dist 0317

Gaussian vs Top Hat: Beam Shape Influences Treatment Uniformity and Efficacy

27 © 2010 Sciton, Inc. All rights reserved.

Sciton delivers a top hat beam. A 10 mm Gaussian single spot has an effective diameter of ~6.5 mm. A top hat 6 mm spot has an effective diameter of 6 mm.

Page 28: Alex launch presentation intl dist 0317

Top Hat Beam: Increased Effective Spot Size Relative to Gaussian Beam

A 6 mm top hat beam retains effective spot size as it penetrates. A 10 mm Gaussian beam loses effective spot size as it penetrates.

7 mmTop Hat

10 mmGaussian

Page 29: Alex launch presentation intl dist 0317

A 6 mm Spot IS EFFICACIOUS: Spot Size vs Depth of Penetration

3mm 6mm 12mm

Spot size will allow the wavelength to realize its maximum penetration depth, but not exceed its inherent potential.

To be efficacious, the spot size must exceed the depth of penetration for 755 nm by four fold.1

755 nm penetrates ~1 mm deep; therefore a minimum spot size needed is 4 mm.

1. Source: “THEORETICAL CONSIDERATIONS IN LASER HAIR REMOVAL”, Ross et. al, 1999

Page 30: Alex launch presentation intl dist 0317

1.5 mm 3 mm 6 mm

For 755 nm, a 6 mm Spot Penetrates to the Necessary Depth to Remove Hair Effectively

A 6 mm spot size penetrates to the necessary depth to remove hair effectively.

Page 31: Alex launch presentation intl dist 0317

Drawbacks of Large Spot Sizes

Large spot size means lower fluence. Harder to treat patients who require higher fluence, have to use smaller spot size.

• Try placing smaller spots in a reliable pattern• How fast are you now with a smaller spot size?

Hard to track where you’ve been with single spots. Scanner offers capability of higher fluence with better control of coverage.

• Single spot and reliably holding at right angle to tissue• Avoid the crescent moon-shaped blistering pattern seen with single spots

31 © 2010 Sciton, Inc. All rights reserved.

Competitors focus on large spot size only because they don’t have a scanner.

Scanner is more versatile, offering different patterns and different shapes.

Page 32: Alex launch presentation intl dist 0317

Myth: You must have a large spot size to be efficacious.

32 © 2010 Sciton, Inc. All rights reserved.

BUSTE

D

Page 33: Alex launch presentation intl dist 0317

Myth #2: “A 6 mm Spot Size Will Be Too Slow.”

Sciton’s scanner technology is FAST• We deliver 50W of Power• Treat a patient at 2.5 cm2/sec, as fast or faster than our major competitors

• Will they tell you their clearing rate? NO.

33 © 2010 Sciton, Inc. All rights reserved.

Page 34: Alex launch presentation intl dist 0317

Nomogram To Determine Speed

A Nomogram is a graphical calculating device and can be used as a quick reference.

Bottom Line: Maximum Average Power determines Speed. Power = Watts = The number of Joules delivered per second.

34 © 2010 Sciton, Inc. All rights reserved.

Page 35: Alex launch presentation intl dist 0317

The Truth About Speed, Power and Clearing Rate

Nomogram Demonstrating Relationship Between Speed, Power, Clearing Rate, Fluence, Energy and Beam Diameter (spot size)

If you keep the fluence the same, to achieve a higher clearing rate, you need higher power. Conversely, lower power will yield a lower clearing rate.

If you keep the power the same and increase fluence, you will decrease the clearing rate.

35 © 2010 Sciton, Inc. All rights reserved.

Page 36: Alex launch presentation intl dist 0317

POWER Determines Speed, Independent of Spot SizeExample: Fluence is 20 J/cm2

Cynosure typical parameters:• 15 mm spot• 20 J/cm2

• 1 Hz • Clearing rate is ~1.8 cm2/sec.• The Power is 35 Watts

Sciton at 20 J/cm2

• 6 mm spot• Clearing rate is 2.5 cm2/sec• ~8.5 Hz• The Power is 50 Watts

36 © 2010 Sciton, Inc. All rights reserved.

Page 37: Alex launch presentation intl dist 0317

Myth: A 6 mm spot will be too slow.

37 © 2010 Sciton, Inc. All rights reserved.

BUSTE

D

Page 38: Alex launch presentation intl dist 0317

38 © 2010 Sciton, Inc. All rights reserved.

EFFECTIVE AND TRUSTED RESULTS

SUPERIOR COMFORT

FAST

EXPANDABLE PLATFORM

The New Era in Alexandrite Laser Hair Removal!

Advantages and Benefits of Sciton’s ClearScan ALX

Page 39: Alex launch presentation intl dist 0317

ClearScan ALX Offers Superior Comfort

• Pre, post, parallel and bulk cooling• Non-sequential scanning• Pressure (Pain Gate theory)

39 © 2010 Sciton, Inc. All rights reserved.

Page 40: Alex launch presentation intl dist 0317

Hierarchy of Cooling

Hierarchy of Cooling

Pre-coolingPost-cooling and pre-cooling

Parallel, post-cooling and pre-coolingBulk, parallel, post-cooling and pre-cooling

40 © 2010 Sciton, Inc. All rights reserved.

Incr

easi

ng C

omfo

rt

Page 41: Alex launch presentation intl dist 0317

The Integrated Cooling Provides Pre-, Post-, Parallel and Bulk Cooling

More aggressive epidermal cooling allows SUPERIOR COMFORT with the benefit of an efficacious treatment

• Ability to deliver more fluence with a smaller spot

Large sapphire provides ability to promote bulk cooling and the ability to apply pressure

41 © 2010 Sciton, Inc. All rights reserved.

Page 42: Alex launch presentation intl dist 0317

Contact Cooling & Advantages of Sapphire Plate

42 © 2010 Sciton, Inc. All rights reserved.

CONCLUSION:

Sapphire contact cooling is significantly more effective than cryogen spray cooling in protecting the epidermis from unwanted thermal damage during laser hair removal……In addition to being more effective, sapphire contact cooling provides protection of the epidermis at significantly lower cost, with no risk of freezing and maximum comfort for the patient by cooling before, during, and after the treatment pulse.

Source: “Epidermal Protection: A Comparative Analysis of Sapphire Contact and Cryogen Spray Cooling’,” Klavuhn, K.G., Laser Hair Removal Technical Note No. 1: January 2000: 1-8,

Page 43: Alex launch presentation intl dist 0317

Contact Cooling & Advantages of Sapphire Plate, cont.

43 © 2010 Sciton, Inc. All rights reserved.

CONCLUSION:

Cryogen Spray Cooling can create an ice film on the epidermis that scatters the laser light and reduces efficacy.

Page 44: Alex launch presentation intl dist 0317

Pain Gate Theory

Pain is controlled by multiple pathways within the central nervous system. (Ronald Melzack and Patrick Wall,1962)

44 © 2010 Sciton, Inc. All rights reserved.

Pain is Controlled by three factors:

1.Activity in the pain fibers - opens the gate

2.Activity in other sensory nerves - closes the gate

3.Messages from the brain - concentrating on the pain or trying not to think about it

The pressure applied with the handpiece provides sensory stimuli to close the pain gate, leading to minimization of pain.

Page 45: Alex launch presentation intl dist 0317

Variation of overlap during hand delivery and placement of sequential adjacent pulses may overheat the

dermal/epidermal junction

Pulse Stacking During Hand Delivery of Pulses

Pulse stacking occurs when subsurface temperature rise produced by an earlier pulse has not dissipated before an adjacent pulse arrives.

45 © 2009 Sciton, Inc. All rights reserved.

Page 46: Alex launch presentation intl dist 0317

Stacked Pulses Cause Blistering and VERY Unhappy Patients

46 © 2010 Sciton, Inc. All rights reserved.

OUCH!Click on image for animation

Page 47: Alex launch presentation intl dist 0317

Non-Sequential Scanning Gives Safe, Comfortable and Uniform Coverage

• Maximizes the time interval between adjacent spots • Minimizes subsurface heat build up• High speed, uniform coverage• Improved efficacy

Easy Fast Accurate

47

Page 48: Alex launch presentation intl dist 0317

Non-sequential scanning -- Better Cooling and Pain Toleration

• Larger spots mean– much more total energy per shot (pain stimulus)– longer cooling time (pain duration)

• Sciton scanner chill plate ensures that heat flows quickly away from body– quicker cooling– higher fluences tolerable with successive pulses widely spaced– maintain high hair clearing rate while minimizing pain

Top view of skin

Sciton scanned pattern of treatment areas cool quicklyLarge spots hit hard, cool

slowly

Page 49: Alex launch presentation intl dist 0317

ClearScan ALX Provides Effective and Trusted Results

• 755 nm is efficacious

• LAPG Scanner• Treatment uniformity

• High Power

49 © 2010 Sciton, Inc. All rights reserved.

Page 50: Alex launch presentation intl dist 0317

ClearScan ALX Offers Treatment Uniformity

Ideal beam shapeComputerized treatment

Complete uniform coverage

50

Page 51: Alex launch presentation intl dist 0317

Candela Single Spot – Tedious and Extremely Difficult to Achieve 100% Uniform Coverage

51 © 2010 Sciton, Inc. All rights reserved.

Click on image for animation

Page 52: Alex launch presentation intl dist 0317

100% Coverage Versus Incomplete Coverage and Lack of Treatment

100% coverage ensures a complete treatment!

52 © 2010 Sciton, Inc. All rights reserved.

Sciton ClearScan ALX Competitor’s single spot hand piece

Page 53: Alex launch presentation intl dist 0317

53 © 2010 Sciton, Inc. All rights reserved.

Additional Benefits of Sapphire Plate Include Decreasing Distance to Dermal Target

CONCLUSION:

…sapphire cools the epidermis before, during, and after the laser pulse, permits beam coupling into the skin, and can provide a convergent beam that maximizes light penetration to the depper dermis. With gentle pressure, such contact devices can also be used to compress the skin, thereby decreasing the distance light must travel to reach dermal targets such as hair follicles.

Source: “Recent Developments in Cutaneous Lasers,” Alora et al, , Lasers in Surgery and Medicine 26: 108-118 (2000)

Page 54: Alex launch presentation intl dist 0317

Summary of ClearScan ALX Advantages

54 © 2010 Sciton, Inc. All rights reserved.

SUPERIOR COMFORT

•Pre, post, parallel and bulk cooling•Ability to apply pressure/pain gate theory•Non-sequential scanning

EFFECTIVE AND TRUSTED RESULTS

•Top-hat Beam•Non-sequential scanning•755 nm works•Uniform Treatment•Maximum coverage

•Pre, post, parallel and bulk cooling

FAST•50 W of high power means fast•Non-sequential scanning

EXPANDABLE PLATFORM

Page 55: Alex launch presentation intl dist 0317

55 © 2010 Sciton, Inc. All rights reserved.

EFFECTIVE AND TRUSTED RESULTS

SUPERIOR COMFORT

FAST

EXPANDABLE PLATFORM

The New Era in Alexandrite Laser Hair Removal!

Advantages and Benefits of Sciton’s ClearScan ALX: How To Sell ClearScan ALX

Page 56: Alex launch presentation intl dist 0317

You Have Three Hair Removal Systems, Which One Should I Buy?

Start by asking:

• Which wavelength do you like?

• Which do you think is best?

• Which one do you prefer?

• What is your patient population?

• Which applications will you be using this for?

56 © 2010 Sciton, Inc. All rights reserved.

Page 57: Alex launch presentation intl dist 0317

You Have Three Hair Removal Systems, Which One Should I Buy? (Cont.)

A busy HR clinic will want both ALX and YAG: There is a perception that ALX is better for lighter skin and YAG for darker skin; however, this is not always the case. This will also vary by country.

A cost-conscious clinic can get by with BBL.

Clinics with many dark skinned (IV-VI) patients need YAG; however, this is not a universal statement.

High vascular will want YAG and may add on ALX.

Most practices need BBL in their office – it’s a staple. Can get good results but operator dependent, not to be used on skin type VI.

ALX is for those who have convinced themselves this is the wavelength they must have.

57 © 2010 Sciton, Inc. All rights reserved.

Page 58: Alex launch presentation intl dist 0317

Why Sciton?

• ClearScan ALX and YAG• Efficacious Treatment for All Skin Types• Rapid Permanent Hair Reduction• No Consumables• Integrated Continuous Contact Cooling• Complete Solution for Any Vascular Lesion

• BBL• Fast• No Consumables• Powerful Cooling• Interchangeable Smart Filters for Personalized Treatment• Predictable & Consistent Results

58 © 2010 Sciton, Inc. All rights reserved.

Page 59: Alex launch presentation intl dist 0317

Table of Contents

59 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 60: Alex launch presentation intl dist 0317

Materials for ClearScan ALX

60 © 2010 Sciton, Inc. All rights reserved.

Marketing Materials Anticipated Date

Product Brochure Mar 5

Website Mar 5

Online Hair Removal Challenge Mar 12

Pricing Quoter Mar 5

Letter to Install Base Mar 5

Physician Testimonials Available

Lifetime Data and Economics of System Available

Supporting Journal Articles Now and ongoing

Print Ads (Aesthetic Buyers Guide) Mar/Apr 2010

eBlast Mar 8

Clinical Studies

OUCH TEST One study completed Feb 2010

SPEED TEST March 2010

Training Webinars

US Mar 3

EMEA/LATAM Mar 16

APAC Mar 17/18

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ClearScan ALX Product Brochure

61 © 2010 Sciton, Inc. All rights reserved.

Page 62: Alex launch presentation intl dist 0317

ClearScan ALX Press Release: March 5th

62 © 2010 Sciton, Inc. All rights reserved.

Page 63: Alex launch presentation intl dist 0317

Hair Removal Challenge

63 © 2010 Sciton, Inc. All rights reserved.

Click on image for animation

Page 64: Alex launch presentation intl dist 0317

ClearScan ALX ConfigurationsConfigurations – New Systems

• ClearScan ALX Single Module• ClearScan ALX with ClearScan YAG, delivered separately• ClearScan ALX with ClearScan YAG multiplexed

• Two Separate Scanners• Integrated Scanner: for 755 nm ClearScan ALX™ or lower fluence 1064 nm ClearScan YAG™ applications (6 mm spot)• HighFluence Integrated Scanner: for 1064 nm ClearScan YAG™ or 1319 nm ThermaScan™ applications (5 mm spot)

• 3 and 6 mm Single Spot Hand pieces

Upgrades: Upgrades will be available in June

64 © 2010 Sciton, Inc. All rights reserved.

Page 65: Alex launch presentation intl dist 0317

Table of Contents

65 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 66: Alex launch presentation intl dist 0317

Four Popular Light Based Methods to Remove Hair

66 © 2010 Sciton, Inc. All rights reserved.

Nd:YAG• 1064 nm• Treats skin types I-VI• Can be painful

Pulsed Light• 590 to 1200 nm• Treats skin types I-V; effective

for light skin/dark hair• Least painful• Result highly dependent on

technique

Alexandrite• 755 nm• Recommended for skin types I-

III but used thru V; standard for HR for skin types I-IV

• Moderate pain

Diode• 800 or 810 nm• Recommended for skin types I-III

and possibly IV & V• Somewhat painful• Difficult to see treatment area

Page 67: Alex launch presentation intl dist 0317

Hair Removal: Competitive Snapshot

67 © 2010 Sciton, Inc. All rights reserved.

Company Model Multi-function Platform Up-gradable System type Wavelength

Sciton

ClearScan YAG Yes Yes Nd: YAG 1064 nm

BBL and BBLs No Yes, if BBL on JOULE Pulsed Light 590 nm, 640 nm, 695 nm

ClearScan ALX Yes Yes Alexandrite 755 nm

AlmaSoprano XL No No Diode 810 nm

Harmony XL No No Pulsed Light 650 nm - 950 nm

CandelaGentleLASE Yes, on GentleMAX n/a Alexandrite 755 nm

GentleYAG Yes, on GentleMAX No Nd:YAG 1064 nm

CuteraCoolGlide Yes, on Xeo platform No Nd:YAG 1064 nm

ProWave 770 Yes, on Solera Opus Platform No Pulsed Light 770 nm – 1100 nm

Cynosure

Cynosure PL No No Pulsed Light 560 nm – 950 nm

Acclaim Yes No Nd:YAG 1064 m

Apogee No No Alexandrite 755 nm

Lumenis

LightSheer Yes, on Lumenis One No Diode 800 nm

IPL Quantum Yes No Pulsed Light 690 nm – 1200 nm

Elora Yes No Pulsed Light 570 – 1200 nm

Palomar LuxG Yes, on StarLux 500 No Pulsed Light 525 nm – 1200 nm

Syneron

eMax/ eLaser DSL No No Diode/ RF Electrical Energy 810 nm

eMax/eLight DS No No Optical Energy/ RF Electrical Energy 600 nm - 980 nm

LightAge LP and LPX No No Alexandrite 755nm

Page 68: Alex launch presentation intl dist 0317

Product Images

68 © 2010 Sciton, Inc. All rights reserved.

Technology

Laser Pulsed Light RFNd:YAG DiodeAlexandrite

ScitonClearScan &

BBL

Sciton BBLs

AlmaSoprano XL

AlmaHarmony XL

CandelaGentleLASE

CandelaGentleYAG Sciton

ALEX

CuteraCoolGlide

CuteraProWave 770

Cynosure PLCynosureAcclaim

CynosureApogee

LumenisLightSheer

LumenisIPL Quantum

LumenisElora

PalomarStarLux 500 Syneron

eMax/ eLaser DSL

ScitonBBL on JOULE

Page 69: Alex launch presentation intl dist 0317

Table of Contents

69 © 2010 Sciton, Inc. All rights reserved.

Introduction to Laser Hair Removal

LHR - Market Overview

Introducing ClearScan ALX

Positioning ClearScan ALX

Marketing Materials Available for ClearScan ALX

Competitive Landscape for Hair Removal

Major ClearScan ALX Competitors

Page 70: Alex launch presentation intl dist 0317

Candela GentleMax and GentleLase: Alexandrite Competitor

70 © 2010 Sciton, Inc. All rights reserved.

Company CANDELA - Note No IPL system  GentleMAX GentleLASELaser Type Alexandrite Nd:YAG AlexandriteWavelength 755 nm 1064 nm 755 nmExpandable? No No NoMax Peak Power 26,400 watts  Max Average Power Not reported    Clearing rate at 20 J/cm2      Fluence up to 600 J/cm² up to 100 J/cm2Pulse Width 0.25-0.50, 3, 5, 10-300 ms 3 ms (fixed pulsed duration)

Single Spot Size-Max Fluence

1.5mm-600 J/cm² 1.5mm-600 J/cm²  3mm-460 J/cm² 3mm-460 J/cm²  

6mm-150 J/cm² (10 Hz but not for hair) 6mm-200 J/cm²

6 mm

8mm-100 J/cm² 8mm-150 J/cm² 8 mm10mm-60 J/cm² 10mm-100 J/cm² 10 mm12mm-40 J/cm² 12mm-70 J/cm² 12 mm – 40 J/cm2

15mm-30 J/cm² (2 Hz) 15mm-44 J/cm² 15 mm – 30 J/cm218mm-20 J/cm² (2 Hz) 18mm-30 J/cm² 18 mm – 20 J/cm2

Repetition Rateup to 10 Hz (only when turn cryogen off, and pulse duration to 0.25 and Joules to 8-10, smaller spots) 1.5 Hz

Scanner No NoScanner spot size NA NA NAAiming Beam Yes Yes Yes

Epidermal Cooling DCD or AirOptional Dynamic Cooling - Cryogen

sprayList Pricing $134,000-200,000 $79,999-98,500 Applications Hair Removal Hair Removal Hair Removal  Pigmented Lesions Leg & Facial Veins Leg & Facial Veins      Wrinkle Reduction  Vascular Lesions Skin Tightening Pigmented LesionsOther claims     Half the size  The hand pieces are considered consumables and run from $2500 to $3000 brand new

Page 71: Alex launch presentation intl dist 0317

Candela Product Positioning

71 © 2010 Sciton, Inc. All rights reserved.

Page 72: Alex launch presentation intl dist 0317

Candela Promotional Materials

Candela has offered hair removal with Alexandrite for several years. They have • Before and After photos• Webinars• Clinical Bulletins• Procedure Videos

Candela heavily promotes that larger spot size means efficacy and speed.

72 © 2010 Sciton, Inc. All rights reserved.

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ClearScan ALX vs Candela

• Candela is a single spot and provides cryogen cooling.• Overlap may result in blisters• Cumbersome to place hundreds of spots over large areas• Uneven treatment coverage• Risk of delivering treatment unevenly if hold handpiece at wrong angle, creating ‘crescent moon’ pattern• Cryogen cooling is inferior to contact cooling

• Simply, it is not as comfortable and can never be as comfortable as the Sciton system

• Sciton offers• Superior comfort• Effective and trusted results with better coverage• Fast• Expandable platform

73 © 2010 Sciton, Inc. All rights reserved.

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Cynosure

Cynosure offers

• Apogee• Elite• Apogee Elite MPX

74 © 2010 Sciton, Inc. All rights reserved.

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Cynosure Apogee and Elite: Alexandrite Competitor

75 © 2010 Sciton, Inc. All rights reserved.

Company CYNOSURE  Apogee EliteLaser Type Alexandrite Alexandrite Nd:YAGWavelength 755 nm 755 nm 1064 nm

Expandable?Yes, can add 1064 and upgrade

to the Elite NoMax Peak Power      Max Average Power Not reported  Not reported  Clearing rate at 20 J/cm2      Fluence    Pulse Width 0.5 - 300 ms 0.5 - 300 ms 0.4 - 300 ms

Single Spot Size-Max Fluence

    1.5 - 600 J/cm2    3 - 300 J/cm2

5 mm - 25 J/cm2 5 - 50 J/cm2 (2 Hz, 5 ms) 5 - 240 J/cm2  7 - 50 J/cm2 (2 Hz, 5 ms) 7 - 160 J/cm2

10 mm - 50 J/cm2 10 - 50 J/cm2 (1 Hz, 5 ms) 10 - 80 J/cm212 mm - 35 J/cm2 12 - 35 J/cm2 (1 Hz, 5 ms) 12 - 50 J/cm215 mm - 25 J/cm2 15 - 25 J/cm2 (1 Hz, 5 ms) 15 - 35 J/cm2

     Repetition Rate 3 Hz 3 Hz 5 Hz

Scanner No No NoScanner spot size NA NA NAAiming Beam Yes Yes Yes

Epidermal Cooling Integrated Zimmer Cold airList Pricing $89,000    Applications Hair Removal Hair removal Hair Removal  Leg and Facial Veins Pigmented Lesions Leg and Facial Veins  Pigmented lesions           Other claims      

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Cynosure Apogee Elite MPX: Alexandrite Competitor

76 © 2010 Sciton, Inc. All rights reserved.

Company CYNOSURE  Apogee Elite MPX*Laser Type Alexandrite Nd:YAG Alexandrite + Nd:YAG XPL2 **

Wavelength755 nm 1064 nm

755 + 1064 nm Multiplexed

Xenon Pulsed Light (530-1200 nm)

Expandable? YES for the Elite MPXMax Peak Power        Max Average Power      Clearing rate at 20 J/cm2        Fluence up to 40 J/cm2 up to 600 J/cm2 up to 200 J/cm2 up to 40 J/cm2Pulse Width 0.5 - 300 ms 0.5 - 300 ms 10 - 40 ms 5-35 ms

Single Spot Size-Max Fluence

  1.5 - 600 J/cm2      3 - 300 J/cm2    5 - 25 J/cm2 5 - 240 J/cm2 5 - 200 J/cm2    7 - 160 J/cm2 7 - 100 J/cm2 1 X 5 cm10 - 50 J/cm2 10 - 90 J/cm2 10 - 70 J/cm2  12 - 40 J/cm2 12 - 60 J/cm2 12 - 50 J/cm2  15 - 30 J/cm2 15 - 40 J/cm2 15 - 32 J/cm2  18 - 22 J/cm2 18 - 27 J/cm2    

Repetition Rate 10 Hz 10 Hz 1.5 Hz 1 HzScanner No No No  Scanner spot size NA NA NA  Aiming Beam Yes Yes Yes  Epidermal Cooling Cold air (`10 deg C @ 350l/min)  List Pricing $120,000-$160,000  Applications Hair Removal Hair Removal   Sun damaged skin  Pigmented Lesions Leg and Facial Veins   Dyschromia        Pigmented lesions

        Diffuse redness, rosaceaOther claims        

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Apogee Elite MPX

Cynosure Product Positioning

77 © 2010 Sciton, Inc. All rights reserved.

Apogee

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Cynosure Promotional Materials

Cynosure’s promotional materials include:• Video• Brochures• Articles in Aesthetic Buyers Guide• Online revenue calculator• Before and After Photos• Clinical Studies cited on their website:

• Analytical Report, Apogee Elite - David M. Cauger – Aesthetic Trends and Technologies, Summer 2004• “Optimized Laser Hair Removal” - Brooke Jackson, MD, Director, Skin Wellness Center of Chicago, Clinical Assistant Professor at Northwestern University• “Customizing Photoepiliation - Caution urged on tanned and light-haired patients” - Beth Kapes - Dermatology Times January 2004

• Their webinars and seminars appear to promote SmartLipo heavily, less emphasis on hair removal

78 © 2010 Sciton, Inc. All rights reserved.

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ClearScan ALX vs Cynosure

• Cynosure is a single spot and requires Zimmer chiller• Overlap may result in blisters• Cumbersome to place hundreds of spots over large areas• Uneven treatment coverage• Risk of delivering treatment unevenly if hold handpiece at wrong angle, creating ‘crescent moon’ pattern• Extra Zimmer chiller

• Simply, it is not as comfortable and can never be as comfortable as the Sciton system

• Sciton offers• Superior comfort• Effective and trusted results with better coverage• Fast• Expandable platform

79 © 2010 Sciton, Inc. All rights reserved.

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Light Age

Light Age Website offers very limited information on system.

Does provide patient videos and testimonials

Single SpotForced Air chiller

80 © 2010 Sciton, Inc. All rights reserved.

Company Light AGEName Epicare LP Epicare LPXLaser Type Alexandrite AlexandriteWavelength 755 nm 755 nmExpandable?    Max Peak Power    Max Average Power 65 W 100 WClearing rate at 20 J/cm2 2.8 cm2 per sec 4.8 cm2 per secPulse Width 3-300 ms 3-300 ms

Single Spot Size-Max Fluence

7 - 40 J/cm2 7 - 40 J/cm29 - 40 J/cm2 9 - 40 J/cm212 - 35 J/cm2 12 - 40 J/cm215 - 22 J/cm2 15 - 35 J/cm2

Repetition Rate 1-3 Hz 1-3 HzScanner No NoAiming Beam Yes YesEpidermal Cooling Integrated cooling Integrated coolingElectrical    Dimensions         Weight    List Pricing $69,000 $89,000 Applications              

Other claims or Notes  

You tube video claims can treat back in 10-20 minutes

     

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BUST THE SPOT SIZE MYTH!

81 © 2010 Sciton, Inc. All rights reserved.

Myth: You must have a large spot size to be efficacious.

Myth: A 6 mm spot will be too slow./You must have a large spot to be fast.

BUSTE

D

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82 © 2010 Sciton, Inc. All rights reserved.

EFFECTIVE AND TRUSTED RESULTS

SUPERIOR COMFORT

FAST

EXPANDABLE PLATFORM

The New Era in Alexandrite Laser Hair Removal!

Key ClearScan ALX Messages

Page 83: Alex launch presentation intl dist 0317

THANK YOU!

Cheryl Deguara, PhD

Product Manager

Office: 650.493.9155, ext. 141

[email protected]

83 © 2010 Sciton, Inc. All rights reserved.