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Airway ManagementAirway Managementin the ICUin the ICU
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Objectives Recognise signs of threatened airway
Describe techniques of establishing airway
and for mask ventilation
Explain proper applications of airwayadjuncts
Describe preparation for endotracheal
intubation and difficult intubation
Describe alternative methods
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Global AssessmentGlobal Assessment
Assess underlying need for airway control Duration of intubation
- Nasal intubation less advantageous for potentially prolonged ventilator
requirements
Permanent support
- Underlying advanced intrinsic lung or neuromuscular disease Temporary support
Anesthesia
Presence of reversible intrinsic lung or neuromuscular disease
Protection of the airway due to depressed mental status
Presence of reversible upper airway pathology
Patient care needs (e.g., transport, CT scan, etc.)
Significant comorbidities
Aspiration potential or increased respiratory secretions
Hemodynamic issues such as cardiac disease or sepsis
Renal or liver failure
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Global AssessmentGlobal Assessment
Pathophysiology of the respiratoryfailure
Hypoxic respiratory failure
- In case of hypoxic respiratory failure, differentnoninvasive oxygen delivery devices can be used.
- The severity of hypoxia and presence or absence of
underlying disease (such as COPD) will dictate the
device of choice.
Hypercapnic respiratory failure
- The noninvasive device of choice for hypercapnic
respiratory failure is BIPAP.
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Global AssessmentGlobal Assessment
Oxygenation Respiratory rate and use of accessory muscles
- Is the patient in respiratory distress?
Amount of supplemental oxygen
- What is the patients oxygen demand?
Airway Anatomy
- Will this patient be difficult to intubate?
Patency
- Is there a reversible anatomical cause of respiratory failure
as opposed to intrinsic lung dysfunction?
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Oxygen Delivery DevicesOxygen Delivery Devices(In order of degree of support)
Nasal Cannula 4% increase in FiO2 for each 1 L of flow (e.g., 4 L flow = 37% or 6 L flow
= 45%)
Face tent At most delivers 40% at 10-15 L flow
Ventimask Small amount of rebreathing
8 L flow = 40%, 15 L flow = 60%
Nonrebreather mask Attached reservoir bag allows 100% oxygen to enter mask withinlet/outlet ports to allow exhalation to escape - does not guarantee
100% delivery.
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Degree of Respiratory DistressDegree of Respiratory Distress
Respiratory pattern Accessory muscle use is an indication of distress.
Rate > 30 can indicate need for more support by noninvasive positive
pressure or intubation
Need for artificial airway
Tongue and epiglottis fall back against posterior pharyngeal wall Nasopharyngeal airway better tolerated
Pulse oximetry
O2 saturation less than 92% on 60 - 100% oxygen can suggest the need
for intubation based on whether there is anything immediately reversible
which could improve ventilation.
Arterial blood gas
pH < 7.3 can indicate need for more support by noninvasive positive
pressure or intubation.
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Temporizing MeasuresTemporizing Measures
Naloxone for narcotic overdose 40 mcg every minute up to 200 mcg with:
- 45 minutes to one hour duration of action
0.4 - 2 mg of naloxone is indicated in patients with respiratory arrest and
history suggestive of narcotic overdose
- There is a potential for pulmonary edema, so large dose is reserved
for known overdose and respiratory arrest
Caution in patients with history of narcotic dependence
Naloxone drip can be titrated starting at half the bolus dose used to
obtain an effect
- Manufacturer recommended 2 mg in 500 ml of normal saline or D5gives 0.004 mg/ml concentration
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Temporizing MeasuresTemporizing Measures (cont'd)
Flumazenil for benzodiazepine overdose 0.2 mg every minute up to 1 mg
Caution in patients with history of benzodiazepine or alcohol dependence
Caution in patients with history of seizure disorder as it will decrease the
seizure threshold
Artificial airway for upper airway obstruction in patientswith oversedation May be necessary in patients with sleep apnea despite judicious sedation
100% oxygen and maintenance of spontaneous
ventilation in patients with pneumothorax Washout of nitrogen may decrease size of pneumothorax
Positive pressure may cause conversion to tension pneumothorax
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Airway Anatomy Suggesting DifficultAirway Anatomy Suggesting Difficult
IntubationIntubation
Length of upper incisors and overriding maxillary teeth
Interincisor (between front teeth) distance < 3 cm (two finger tips)
Thyromental distance < 7 cm
tip of mandible to hyoid bone (three finger breaths)
Neck extension < 35 degrees
Sternomental distance < 12.5 cm
With the head fully extended and mouth closed
Narrow palate (less than three finger breaths)
Mallampati score class III or IV
Stiff joint syndrome About one third of diabetics characterized by short stature, joint rigidity, and tight waxy skin
Positive prayer sign with an inability to oppose fingers
No sign is foolproof to indicate intubation difficulty
Erden V, et al. Brit J Anesth. 2003;91:159-160.
Prayer Sign
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Mallampati ScoreMallampati Score
Class I: Uvula/tonsillar pillars visible
Class II: Tip of uvula/pillars hidden by tongue
Class III: Only soft palate visible
Class IV: Only hard palate visible
Den Herder, et al. Laryngoscope. 2005;115(4):735-739.
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ComorbiditiesComorbidities
Potential for aspiration requires rapid sequence intubation withcricoid pressure
Clear liquids < 4 hours
Particulate or solids < 6hours
Potential for hypotension
Cardiac dysfunction, hypovolemia, and sepsis May need to consider awake intubation with topical anesthesia
(aerosolized lidocaine) as sedation may precipitate hemodynamic
compromise and even arrest.
Organ failure
Renal and hepatic failure will limit medication used.
Potential for preexisting pulmonary edema and airway bleeding from
manipulation
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Induction AgentsInduction Agents
Sodium Thiopental 3 - 5 mg/kg IV
Profound hypotension in patients with hypovolemia, histamine release, arteritis
Dose should be decreased in both renal and hepatic failure.
Propofol 2 - 3 mg/kg IV
Hypotension, especially in patients with systolic heart dysfunction, bradycardia,and even heart block
Unlikely to have prolonged effect in organ failure
Ketamine 1 - 4 mg/kg IV, 5 - 10 mg/kg IM
Stimulates sympathetic nervous system
Requires atropine due to stimulated salivation and midazolam for potential ofdysphoria
Avoid in patients with loss of autoregulation and closed head injury
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Neuromuscular BlockersNeuromuscular Blockers
Succinylcholine 1 - 2 mg/kg IV, 4 mg/kg IM
Avoid in patients with malignant hyperthermia, > 24 hours out from burn or
trauma injury, upper motor neuron injury, and preexisting hyperkalemia
Rocuronium
0.6 - 1.2 mg/kg, highest dose required for rapid sequence Hemodynamically stable, 10% renal elimination
Vecuronium 0.1 mg/kg
Hemodynamically stable, 10% renal elimination
Cisatricurium 0.2 mg/kg
Mild histamine release, Hoffman degradation, not prolonged in renal or
hepatic failure
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Rapid Sequence IntubationRapid Sequence Intubation
Preoxygenate for three to five minutes prior to induction Wash out nitrogen to avoid premature desaturation during intubation.
Cricoid pressure should be applied from prior to induction until
confirmation of appropriate placement.
Succinylcholine 1 - 2 mg/kg IV will achieve intubationconditions in 30 seconds; Rocuronium 1.2 mg/kg IV will
achieve intubation conditions in 45 seconds.
Other muscle relaxants do not produce intubation conditions in less than
60 seconds.
Avoid mask ventilation after induction. Potentially can inflate stomach
Use only if necessary to ensure appropriate oxygenation during
prolonged intubation.
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Y BAG PEOPLEY BAG PEOPLE (Reference #6)
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Cricoid PressureCricoid Pressure
Cricoid is circumferential
cartilage
Pressure obstructsesophagus to prevent
escape of gastric
contents
Maintains airway patency
Koziol C, et al. AORN. 2000;72(6):1018-1030.
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SniffingPositionSniffingPosition
Align oral, pharyngeal, and laryngeal axes to
bring epiglottis and vocal cords into view.
Hirsch N, et al. Anesthesiology. 2000;93(5):1366.
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Mask VentilationMask Ventilation
Mask ventilation crucial,especially in patients who are
difficult to intubate
Sniffing position with tight
mask fit optimal
May require two hands
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Oral/Nasal AirwaysOral/Nasal Airways
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Laryngoscope Blades and EndotrachealLaryngoscope Blades and Endotracheal
TubesTubes
Miller blade: End of blade should be under epiglottis
Mac blade: End of blade should be placed in front of epiglottis in valecula
ETT for Fastrach LMA
Pediatric uncuffed ETT
ETT for blind nasal
Standard ETT
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Graded Views on IntubationGraded Views on Intubation
Grade 1: Full glottis visible
Grade 2: Only posterior commissure
Grade 3: Only epiglottis
Grade 4: No glottis structures are visible
Yarnamoto K, et al. Anesthesiology. 1997;86(2):316.
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Confirmation ofPlacementConfirmation ofPlacement
Direct visualization
Humidity fogging the endotracheal tube
End tidal CO2 which is maintained after > 5 breaths
Low cardiac output results in decreased delivery of CO2
Refill in 5 seconds of self-inflating bulb at the end of the
endotracheal tube
Symmetrical chest wall movement
Bilateral breath soundsMaintenance of oxygenation by pulse oximetry
Absence of epigastric auscultation during ventilation
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Additional ConsiderationsAdditional Considerations
Always have additional personnel and an experiencedprovider as backup available for potential failed
intubation
Always have suction available
Never give a muscle relaxant if difficult mask ventilation
is demonstrated or expected
Awake intubation should be considered in the following: If patient is so hemodynamically unstable that induction drugs cannot be
tolerated (topicalize airway)
If patient has a history or an exam which suggests difficult mask
ventilation and/or direct laryngoscopy
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Alternative MethodsAlternative Methods
Blind nasal intubation
Bleeding may cause problems with subsequent attempts.
Contraindicated in patients with facial trauma due to cribiform plate disruption or
CSF leak
Avoid in immune suppressed (i.e., bone marrow transplant)
Eschmann stylet
Fiber optic bronchoscopic intubation Awake vs. asleep
Laryngeal mask airway
Allows ventilation while bridging to more definitive airway
Light wand
Retrograde intubation Through cricothyrotomy
Surgical tracheostomy
Combitube
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Eschman StyletEschman Stylet
Use especially if Grade IIIview achieved
Direct laryngoscopy isperformed
Place Eschman wheretrachea is anticipated
May feel tracheal ringsagainst stiffness of stylet
Thread 7.0 or 7.5 ETTover stylet with thelaryngoscope still in place
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The Laryngeal Mask Airway (LMA)The Laryngeal Mask Airway (LMA)
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LMA PlacementLMA Placement
Guide the LMA along the
palate
Eventual position should
be underneath the
epiglottis, in front of thetracheal opening, with the
tip in the esophagus
FOB placement through
LMA positions in front oftrachea
Martin S, et al. J Trauma Injury, Infection Crit Care.
1999;47(2):352-357.
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The FastrachThe FastrachTMTM LaryngealLaryngeal
Mask AirwayMask Airway
Reinforced LMA allows for
passage of ETT without
visualization of trachea.
10% failure rate in
experienced hands
20% failure rate in
inexperienced
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The Light WandThe Light Wand
Transillumination of tracheawith light at distal end
Trachea not visualizeddirectly
Should not be used with
tumors, trauma, or foreignbodies of upper airway
Minimal complicationexcept for mucosal bleed
10% failure rate on firstattempt in experiencedhands
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Retrograde IntubationRetrograde Intubation
Puncture of thecricothyroid membrane
with retrograde passage of
a wire to the trachea
Endotracheal tube guidedendoscopically over the
wire through the trachea
Catheter through the
cricothyroid can be usedfor jet ventilation if
necessary.
Wesler N, et al. Acta Anaes Scan. 2004;48(4):412-416.
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CombitubeCombitube (cont'd)
Should be changed to endotracheal tube (ETT) ortracheostomy to prevent progressive airway edema
If in esophagus, take down pharyngeal cuff and attempt direct
laryngoscopy (DL) or fiber optic bronchoscope (FOB)
placement around combitube
Failed exchange attempt can be solved with operative
tracheostomy
Placement of combitube can produce significant airway
trauma Removal prior to DL or FOB should be done with caution after thorough airway
evaluation
Cricoid pressure should be maintained and emergency tracheostomy equipment
available
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TracheostomyTracheostomy
Surgical airway throughthe cervical trachea
Emergent procedure
carries risk of bleedingdue to proximity ofinnominate artery
Can be difficult and timeconsuming in emergent
situations
SharpeM, et al. Laryngoscope. 2003;113(3):530-536.
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ReferencesReferences
1. Caplan RA
, et al. Practice guidelines for management of thedifficult airway.Anesthesiology. 1993;78:597-602.
2. Langeron O, et al. Predictors of difficult mask ventilation.
Anesthesiology. 2000;92:1229-36.
3. Frerk CM, et al. Predicting difficult intubation.Anaesthesia.
1991;46:1005-08.4. Tse JC, et al. Predicting difficult endotracheal intubation in
surgical patients scheduled for general anesthesia.
Anesthesia & Analgesia. 1995;81:254-8.
5. Benumof JL, et al. LMA and the ASA difficult airway
algorithm.Anesthesiology. 1996;84:686-99.
6. Reynolds S, Heffner J. Airway management of the critically
ill patient. Chest. 2005;127:1397-1412.