Advancing Science with DNA Sequence Response to BERAC Review • Overview of JGI • BERAC Recommendations – Managing multi-lab environment – Operation of user facility – LSP program • JGI Energy Portfolio QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture.
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Advancing Science with DNA Sequence Response to BERAC Review Overview of JGI BERAC Recommendations –Managing multi-lab environment –Operation of user facility.
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Advancing Science with DNA Sequence
Response to BERAC Review
• Overview of JGI
• BERAC Recommendations– Managing multi-lab environment– Operation of user facility– LSP program
• JGI Energy Portfolio
QuickTime™ and aTIFF (Uncompressed) decompressor
are needed to see this picture.
Advancing Science with DNA Sequence
JGI Mission
“User facility providing DNA sequencing & analysis in support of DOE missions in alternative energy, carbon cycling & bioremediation.”
JGI User Meeting, April 2006250 Users and potential usersSequence-based science talksTours of JGI facilityPoster sessionsUser Committee formed
Advancing Science with DNA Sequence
JGI Director
PGF LBNLLANL ORNL LLNL SHGCPNNL
The JGI Partnership
Managing in a multi-lab environment: Dual workforce at PGF
Succession planning at PGF
Coordination of partner tasks
Advancing Science with DNA Sequence
BERAC RecommendationsOperations and Management-1
• Management of LBL/LLNL workforce
– Coordination of safety training & tracking• EH&S MOU complete, waiting signatures• LBL has 1º responsibility for EH&S
– Cyber-security MOU• Committee configured, meets this month
Advancing Science with DNA Sequence
BERAC RecommendationsOperations and Management-2
• Succession planning for key JGI positions
– Hired production sequencing lead
– Senior managers identified “seconds”
– Seconds contribute to weekly mgmt meetings
Advancing Science with DNA Sequence
BERAC RecommendationsOperations and Management-3
Coordination of JGI partner lab tasks:
• Weekly genome management conference call• Monthly partners conference call• “Finishing in the future” meeting• Eukaryotic Genome Program summit
Advancing Science with DNA Sequence
BERAC RecommendationsUser Facility
Proposals
Sequencing
Annotation
UserAgreement
DNALibraries
Asssembly
Sequencingscales easily
Efficiency of the user facility:
Peer review
Project management
Assembly & annotation throughput
Advancing Science with DNA Sequence
BEERAC RecommendationsUser Facility-1
• Managing the User Facility:
– Peer review• MGP and CSP programs/review groups merged• Broadened geographical representation• Electronic proposal submission & review• Letter-of-intent process• User committee input on peer review committees
Advancing Science with DNA Sequence
BEERAC RecommendationsUser Facility-2
• Managing the User Facility:
– Formal project management• Appointed project management lead• Hired 2 new project managers• Launched Global Project Tracking System• End-of-project survey in draft form
Advancing Science with DNA Sequence
BERAC RecommendationsUser Facility-3
• Managing the User Facility:
– Improve large genome analysis throughput• JAZZ assembly program overhauled• 2 programmers hired into assembly group• 3 people hired into annotation group
Advancing Science with DNA Sequence
Lab Science Program
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• LSP created by new JGI MOU – Facilitate access to JGI for Natl. Lab
investigators– Fulfill programmatic sequencing
needs of DOE– Shape JGI products and services to
meet needs of the Natl. Labs
• BERAC concerns– Scientific vision for LSP– Implementation
Advancing Science with DNA Sequence
BERAC RecommendationsLSP Program
• LSP lead– Appointed Jerry Tuskan, ORNL, Jan ‘06– Focus on bioenergy– LSP lead now reports to JGI Director
• Implementation– Lab points-of-contact identified– Small-scale sequencing program
• 14 proposals received, 10 approved to date
– Large-scale sequencing program• Plant Genomes for Energy white paper• Fungal Genomes for Energy white paper